JP2008546422A5 - - Google Patents
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- Publication number
- JP2008546422A5 JP2008546422A5 JP2008519378A JP2008519378A JP2008546422A5 JP 2008546422 A5 JP2008546422 A5 JP 2008546422A5 JP 2008519378 A JP2008519378 A JP 2008519378A JP 2008519378 A JP2008519378 A JP 2008519378A JP 2008546422 A5 JP2008546422 A5 JP 2008546422A5
- Authority
- JP
- Japan
- Prior art keywords
- dna molecule
- dna
- synthesizing
- dideoxy
- deoxyribonucleotides
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 108020004414 DNA Proteins 0.000 description 5
- 102000053602 DNA Human genes 0.000 description 5
- 230000002194 synthesizing effect Effects 0.000 description 2
- 102000016928 DNA-directed DNA polymerase Human genes 0.000 description 1
- 108010014303 DNA-directed DNA polymerase Proteins 0.000 description 1
- 230000000295 complement effect Effects 0.000 description 1
- 239000005547 deoxyribonucleotide Substances 0.000 description 1
- 125000002637 deoxyribonucleotide group Chemical group 0.000 description 1
- 239000002342 ribonucleoside Substances 0.000 description 1
- -1 ribonucleoside triphosphates Chemical class 0.000 description 1
- 239000001226 triphosphate Substances 0.000 description 1
- 235000011178 triphosphate Nutrition 0.000 description 1
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US11/170,762 US20060292578A1 (en) | 2005-06-28 | 2005-06-28 | DNA polymerase blends and mutant DNA polymerases |
| PCT/US2006/023899 WO2007002031A2 (en) | 2005-06-28 | 2006-06-20 | Dna polymerase blends and mutant dna polymerases |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2008546422A JP2008546422A (ja) | 2008-12-25 |
| JP2008546422A5 true JP2008546422A5 (enExample) | 2012-07-12 |
Family
ID=37567925
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2008519378A Pending JP2008546422A (ja) | 2005-06-28 | 2006-06-20 | Dnaポリメラーゼブレンドおよび突然変異型dnaポリメラーゼ |
Country Status (6)
| Country | Link |
|---|---|
| US (3) | US20060292578A1 (enExample) |
| EP (2) | EP1904518B1 (enExample) |
| JP (1) | JP2008546422A (enExample) |
| AT (1) | ATE484515T1 (enExample) |
| DE (1) | DE602006017551D1 (enExample) |
| WO (1) | WO2007002031A2 (enExample) |
Families Citing this family (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20060292578A1 (en) * | 2005-06-28 | 2006-12-28 | Weidong Zheng | DNA polymerase blends and mutant DNA polymerases |
| US9617588B2 (en) | 2010-10-05 | 2017-04-11 | Thermo Fisher Scientific Baltics Uab | Enzyme mixture |
| US8932813B2 (en) | 2010-12-13 | 2015-01-13 | Life Technologies Corporation | Polymerization of nucleic acids using activation by polyphosphorolysis (APP) reactions |
| US9567628B2 (en) | 2011-06-08 | 2017-02-14 | Life Technologies Corporation | Polymerization of nucleic acids using proteins having low isoelectric points |
| FI3461807T3 (fi) | 2011-06-08 | 2023-09-07 | Life Technologies Corp | Uudenlaisten detergenttien suunnittelu ja kehitys pcr-järjestelmissä käyttöä varten |
| DK2914741T3 (da) | 2012-11-02 | 2017-11-20 | Life Technologies Corp | Hidtil ukendte sammensætninger og fremgangsmåder til forbedring af PCR-specificitet |
| TWI487789B (zh) * | 2012-12-24 | 2015-06-11 | Ind Tech Res Inst | 單離的脫氧核糖核酸聚合酶、套組與其應用 |
| KR101417989B1 (ko) * | 2013-02-08 | 2014-07-09 | 주식회사 엔지노믹스 | 이중가닥 dna 말단의 단일가닥 길이 조절 방법 |
| EP2971095B1 (en) | 2013-03-12 | 2019-11-20 | Life Technologies Corporation | Universal reporter-based genotyping methods, reaction mixture and kit |
| EP3539944A1 (en) | 2013-10-25 | 2019-09-18 | Life Technologies Corporation | Novel compounds for use in pcr systems and applications thereof |
| EP3967768A1 (en) | 2015-03-13 | 2022-03-16 | Life Technologies Corporation | Compositions for small rna capture, detection and quantification |
| WO2025235589A1 (en) * | 2024-05-08 | 2025-11-13 | Codexis, Inc. | Dna polymerase variants |
Family Cites Families (38)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US599594A (en) | 1898-02-22 | Washing-machine | ||
| US4965188A (en) | 1986-08-22 | 1990-10-23 | Cetus Corporation | Process for amplifying, detecting, and/or cloning nucleic acid sequences using a thermostable enzyme |
| US5374553A (en) | 1986-08-22 | 1994-12-20 | Hoffmann-La Roche Inc. | DNA encoding a thermostable nucleic acid polymerase enzyme from thermotoga maritima |
| US5079352A (en) | 1986-08-22 | 1992-01-07 | Cetus Corporation | Purified thermostable enzyme |
| US4889818A (en) | 1986-08-22 | 1989-12-26 | Cetus Corporation | Purified thermostable enzyme |
| US4795699A (en) | 1987-01-14 | 1989-01-03 | President And Fellows Of Harvard College | T7 DNA polymerase |
| US5173411A (en) | 1987-01-14 | 1992-12-22 | President And Fellows Of Harvard College | Method for determining the nucleotide base sequence of a DNA molecule |
| US5244797B1 (en) | 1988-01-13 | 1998-08-25 | Life Technologies Inc | Cloned genes encoding reverse transcriptase lacking rnase h activity |
| US4962020A (en) | 1988-07-12 | 1990-10-09 | President And Fellows Of Harvard College | DNA sequencing |
| US5498523A (en) | 1988-07-12 | 1996-03-12 | President And Fellows Of Harvard College | DNA sequencing with pyrophosphatase |
| US5047342A (en) | 1989-08-10 | 1991-09-10 | Life Technologies, Inc. | Cloning and expression of T5 DNA polymerase |
| US5270179A (en) | 1989-08-10 | 1993-12-14 | Life Technologies, Inc. | Cloning and expression of T5 DNA polymerase reduced in 3'- to-5' exonuclease activity |
| US5210015A (en) | 1990-08-06 | 1993-05-11 | Hoffman-La Roche Inc. | Homogeneous assay system using the nuclease activity of a nucleic acid polymerase |
| JP2709311B2 (ja) | 1990-09-28 | 1998-02-04 | エフ.ホフマン−ラ ロシュ アクチェンゲゼルシャフト | 熱安定性dnaポリメラーゼの5→3′のエキソヌクレアーゼ突然変異 |
| AU8906091A (en) | 1990-10-05 | 1992-04-28 | Wayne M. Barnes | Thermostable dna polymerase |
| US5994056A (en) | 1991-05-02 | 1999-11-30 | Roche Molecular Systems, Inc. | Homogeneous methods for nucleic acid amplification and detection |
| US5436149A (en) | 1993-02-19 | 1995-07-25 | Barnes; Wayne M. | Thermostable DNA polymerase with enhanced thermostability and enhanced length and efficiency of primer extension |
| US5556772A (en) * | 1993-12-08 | 1996-09-17 | Stratagene | Polymerase compositions and uses thereof |
| US5512462A (en) | 1994-02-25 | 1996-04-30 | Hoffmann-La Roche Inc. | Methods and reagents for the polymerase chain reaction amplification of long DNA sequences |
| US5912155A (en) | 1994-09-30 | 1999-06-15 | Life Technologies, Inc. | Cloned DNA polymerases from Thermotoga neapolitana |
| US5614365A (en) | 1994-10-17 | 1997-03-25 | President & Fellow Of Harvard College | DNA polymerase having modified nucleotide binding site for DNA sequencing |
| US6130364A (en) | 1995-03-29 | 2000-10-10 | Abgenix, Inc. | Production of antibodies using Cre-mediated site-specific recombination |
| WO1997009451A1 (en) | 1995-09-08 | 1997-03-13 | Life Technologies, Inc. | Cloned dna polymerases from thermotoga and mutants thereof |
| US5789166A (en) * | 1995-12-08 | 1998-08-04 | Stratagene | Circular site-directed mutagenesis |
| JP4540754B2 (ja) | 1996-06-04 | 2010-09-08 | ユニバーシティ オブ ユタ リサーチ ファウンデーション | Pcr中のハイブリダイゼーションのモニタリング |
| CZ293215B6 (cs) * | 1996-08-06 | 2004-03-17 | F. Hoffmann-La Roche Ag | Rekombinantní tepelně stálá DNA polymeráza, způsob její přípravy a prostředek, který ji obsahuje |
| EP2264045B1 (en) | 1996-08-14 | 2015-10-21 | Life Technologies Corporation | Stable compositions for nucleic acid amplification and sequencing |
| US5994076A (en) | 1997-05-21 | 1999-11-30 | Clontech Laboratories, Inc. | Methods of assaying differential expression |
| US6228628B1 (en) * | 1997-07-09 | 2001-05-08 | Roche Molecular Systems | Mutant chimeric DNA polymerase |
| ATE502043T1 (de) * | 1997-08-29 | 2011-04-15 | Life Technologies Corp | Hochempfindliche polymerasen und ihre verwendungen |
| WO2003004632A2 (en) * | 2001-07-06 | 2003-01-16 | Amersham Biosciences Corp | Novel dna polymerases having amino acid substitutions and homologs thereof |
| CA2459718A1 (en) * | 2001-09-14 | 2003-08-14 | Applera Corporation | Thermus scotoductus nucleic acid polymerases |
| US20070020622A1 (en) | 2001-09-14 | 2007-01-25 | Invitrogen Corporation | DNA Polymerases and mutants thereof |
| JP2005511043A (ja) * | 2001-11-30 | 2005-04-28 | アプレラ コーポレイション | Thermusthermophilus核酸ポリメラーゼ |
| CN100468638C (zh) | 2001-12-18 | 2009-03-11 | 松下电器产业株式会社 | 半导体元件的制造方法 |
| US7960157B2 (en) * | 2002-12-20 | 2011-06-14 | Agilent Technologies, Inc. | DNA polymerase blends and uses thereof |
| EP1641936B1 (en) * | 2003-06-17 | 2010-08-04 | Human Genetic Signatures PTY Ltd. | Methods for genome amplification |
| US20060292578A1 (en) | 2005-06-28 | 2006-12-28 | Weidong Zheng | DNA polymerase blends and mutant DNA polymerases |
-
2005
- 2005-06-28 US US11/170,762 patent/US20060292578A1/en not_active Abandoned
-
2006
- 2006-06-20 JP JP2008519378A patent/JP2008546422A/ja active Pending
- 2006-06-20 AT AT06799952T patent/ATE484515T1/de not_active IP Right Cessation
- 2006-06-20 EP EP06799952A patent/EP1904518B1/en active Active
- 2006-06-20 WO PCT/US2006/023899 patent/WO2007002031A2/en not_active Ceased
- 2006-06-20 DE DE602006017551T patent/DE602006017551D1/de active Active
- 2006-06-20 EP EP10174796.2A patent/EP2314596B1/en active Active
-
2008
- 2008-03-20 US US12/052,682 patent/US9376698B2/en active Active
-
2016
- 2016-06-03 US US15/173,439 patent/US20160272955A1/en not_active Abandoned
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