JP2008545756A - 癌化学療法剤として有用な１−メチル−１ｈ−ピラゾール−４−カルボキサミド類 - Google Patents

癌化学療法剤として有用な１−メチル−１ｈ−ピラゾール−４−カルボキサミド類 Download PDF

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Publication number
JP2008545756A
JP2008545756A JP2008514922A JP2008514922A JP2008545756A JP 2008545756 A JP2008545756 A JP 2008545756A JP 2008514922 A JP2008514922 A JP 2008514922A JP 2008514922 A JP2008514922 A JP 2008514922A JP 2008545756 A JP2008545756 A JP 2008545756A
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JP
Japan
Prior art keywords
alkyl
alkoxy
substituted
groups
halo
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2008514922A
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English (en)
Japanese (ja)
Inventor
フィリップ・ウィッケンズ
ハロルド・シー・イー・クルエンダー
ホン・チェンキウ
エララヘワゲ・サティアジト・クマラシンゲ
チャールズ・クレイマン
チャン・ミンバオ
イシュトヴァン・エンイェディ
チー−ユアン・チュアン
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Bayer AG
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Bayer Healthcare AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer Healthcare AG filed Critical Bayer Healthcare AG
Publication of JP2008545756A publication Critical patent/JP2008545756A/ja
Pending legal-status Critical Current

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/14—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
JP2008514922A 2005-06-03 2006-06-02 癌化学療法剤として有用な１−メチル−１ｈ−ピラゾール−４−カルボキサミド類 Pending JP2008545756A (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US68745405P 2005-06-03 2005-06-03
PCT/US2006/021550 WO2006133006A2 (fr) 2005-06-03 2006-06-02 1-methyl-1h-pyrazole-4-carboxamides utiles comme agents chimiotherapeutiques anticancereux

Publications (1)

Publication Number Publication Date
JP2008545756A true JP2008545756A (ja) 2008-12-18

Family

ID=37498955

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2008514922A Pending JP2008545756A (ja) 2005-06-03 2006-06-02 癌化学療法剤として有用な１−メチル−１ｈ−ピラゾール−４−カルボキサミド類

Country Status (4)

Country Link
EP (1) EP1891047A4 (fr)
JP (1) JP2008545756A (fr)
CA (1) CA2610509A1 (fr)
WO (1) WO2006133006A2 (fr)

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2013503901A (ja) * 2009-09-03 2013-02-04 アラーガン インコーポレイテッド チロシンキナーゼ調節剤としての化合物
JP2013506715A (ja) * 2009-10-06 2013-02-28 ミレニアム ファーマシューティカルズ， インコーポレイテッド Ｐｄｋ１インヒビターとして有用な複素環式化合物
WO2017043563A1 (fr) * 2015-09-08 2017-03-16 参天製薬株式会社 Procédé de production de pyridine-carboxamide

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9340555B2 (en) 2009-09-03 2016-05-17 Allergan, Inc. Compounds as tyrosine kinase modulators
EP2788349B1 (fr) 2011-12-09 2016-10-26 Chiesi Farmaceutici S.p.A. Inhibiteurs de kinase
JP6145849B2 (ja) 2011-12-09 2017-06-14 チエシ ファルマスーティシ エス．ピー．エー． キナーゼ阻害剤
KR20160018567A (ko) 2013-06-06 2016-02-17 키에시 파르마슈티시 엣스. 피. 에이. 키나아제 억제제
EP3692045A1 (fr) 2017-10-04 2020-08-12 Bayer Aktiengesellschaft Dérivés hétérocycliques utilisés comme pesticides
ES2929476T3 (es) 2018-03-12 2022-11-29 Bayer Ag Derivados heterocíclicos bicíclicos condensados como plaguicidas
JP2021522182A (ja) 2018-04-20 2021-08-30 バイエル・アクチエンゲゼルシヤフト 殺有害生物剤としてのヘテロシクレン誘導体

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6878714B2 (en) * 2001-01-12 2005-04-12 Amgen Inc. Substituted alkylamine derivatives and methods of use
WO2003037336A1 (fr) * 2001-11-02 2003-05-08 Pfizer Products Inc. Derives de 1-(5-sulfonyl-pyridin-2-yl)-5-(methylidene-cycloalkylmethoxy)-1h-pyrazole-4-carbonitrile et autres composes utilises en tant qu'inhibiteurs de la cyclooxygenase dans le traitement de l'arthrite, de la neurodegeneration et du cancer du colon

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2013503901A (ja) * 2009-09-03 2013-02-04 アラーガン インコーポレイテッド チロシンキナーゼ調節剤としての化合物
JP2013506715A (ja) * 2009-10-06 2013-02-28 ミレニアム ファーマシューティカルズ， インコーポレイテッド Ｐｄｋ１インヒビターとして有用な複素環式化合物
US10030016B2 (en) 2009-10-06 2018-07-24 Sunesis Pharmaceuticals, Inc. Heterocyclic compounds useful as PDK1 inhibitors
WO2017043563A1 (fr) * 2015-09-08 2017-03-16 参天製薬株式会社 Procédé de production de pyridine-carboxamide

Also Published As

Publication number Publication date
EP1891047A2 (fr) 2008-02-27
EP1891047A4 (fr) 2008-07-09
WO2006133006A2 (fr) 2006-12-14
WO2006133006A3 (fr) 2007-02-22
CA2610509A1 (fr) 2006-12-14

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