JP2008545426A - 高親和性メラン−at細胞レセプター - Google Patents

高親和性メラン−at細胞レセプター Download PDF

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Publication number
JP2008545426A
JP2008545426A JP2008514187A JP2008514187A JP2008545426A JP 2008545426 A JP2008545426 A JP 2008545426A JP 2008514187 A JP2008514187 A JP 2008514187A JP 2008514187 A JP2008514187 A JP 2008514187A JP 2008545426 A JP2008545426 A JP 2008545426A
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JP
Japan
Prior art keywords
tcr
seq
chain
chain variable
variable region
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Pending
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JP2008514187A
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English (en)
Japanese (ja)
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JP2008545426A5 (enExample
Inventor
ヤコブセン,ベント,カルステン
リッディ,ナサニエル,ロス
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Medigene Ltd
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Medigene Ltd
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Application filed by Medigene Ltd filed Critical Medigene Ltd
Publication of JP2008545426A publication Critical patent/JP2008545426A/ja
Publication of JP2008545426A5 publication Critical patent/JP2008545426A5/ja
Pending legal-status Critical Current

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    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/70503Immunoglobulin superfamily
    • C07K14/7051T-cell receptor (TcR)-CD3 complex
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Biophysics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Genetics & Genomics (AREA)
  • Zoology (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Toxicology (AREA)
  • Cell Biology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Biochemistry (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Medicinal Preparation (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
JP2008514187A 2005-06-01 2006-05-31 高親和性メラン−at細胞レセプター Pending JP2008545426A (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB0511124.0A GB0511124D0 (en) 2005-06-01 2005-06-01 High affinity melan-a t cell receptors
PCT/GB2006/001980 WO2006129085A2 (en) 2005-06-01 2006-05-31 High affinity melan-a t cell receptors

Publications (2)

Publication Number Publication Date
JP2008545426A true JP2008545426A (ja) 2008-12-18
JP2008545426A5 JP2008545426A5 (enExample) 2009-07-09

Family

ID=34834931

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2008514187A Pending JP2008545426A (ja) 2005-06-01 2006-05-31 高親和性メラン−at細胞レセプター

Country Status (12)

Country Link
US (1) US8217144B2 (enExample)
EP (1) EP1893642A2 (enExample)
JP (1) JP2008545426A (enExample)
CN (1) CN101189261B (enExample)
AU (1) AU2006253941B2 (enExample)
BR (1) BRPI0611326A2 (enExample)
CA (1) CA2610786A1 (enExample)
EA (1) EA012507B1 (enExample)
GB (1) GB0511124D0 (enExample)
MX (1) MX2007014919A (enExample)
WO (1) WO2006129085A2 (enExample)
ZA (1) ZA200710009B (enExample)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2018527954A (ja) * 2015-09-15 2018-09-27 アダプティミューネ リミテッドAdaptimmune Limited Tcrライブラリ

Families Citing this family (29)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7994298B2 (en) 2004-09-24 2011-08-09 Trustees Of Dartmouth College Chimeric NK receptor and methods for treating cancer
WO2008039818A2 (en) * 2006-09-26 2008-04-03 Government Of The United States Of America, Represented By The Secretary, Department Of Health And Human Services Modified t cell receptors and related materials and methods
EP2087000A2 (en) * 2006-09-29 2009-08-12 Immunocore Ltd. T cell therapies
US8119772B2 (en) 2006-09-29 2012-02-21 California Institute Of Technology MART-1 T cell receptors
GB0816096D0 (en) * 2008-09-04 2008-10-15 Medigene Ltd Diabetes t cell receptors
GB0911566D0 (en) 2009-07-03 2009-08-12 Immunocore Ltd T cell receptors
WO2011059836A2 (en) 2009-10-29 2011-05-19 Trustees Of Dartmouth College T cell receptor-deficient t cell compositions
US9273283B2 (en) 2009-10-29 2016-03-01 The Trustees Of Dartmouth College Method of producing T cell receptor-deficient T cells expressing a chimeric receptor
US12492376B2 (en) 2009-10-29 2025-12-09 The Trustees Of Dartmouth College T-cell receptor-deficient T cell compositions
CA3080181A1 (en) * 2011-03-04 2012-09-13 Shire Human Genetic Therapies, Inc. Peptide linkers for polypeptide compositions and methods for using same
US9833476B2 (en) 2011-08-31 2017-12-05 The Trustees Of Dartmouth College NKP30 receptor targeted therapeutics
RU2665548C2 (ru) * 2012-05-03 2018-08-30 Фред Хатчинсон Кансэр Рисёч Сентер Способ получения клеток, экспрессирующих т-клеточный рецептор
WO2013169691A1 (en) 2012-05-07 2013-11-14 Trustees Of Dartmouth College Anti-b7-h6 antibody, fusion proteins, and methods of using the same
AU2013308409A1 (en) 2012-08-31 2015-03-26 University Of Birmingham Target peptides for immunotherapy and diagnostics
EP2892544A4 (en) 2012-09-05 2016-11-02 Univ Virginia Patent Found TARGET PEPTIDES FOR THERAPY AND DIAGNOSIS OF COLORECTAL CARCINOMAS
EP3071594A4 (en) * 2013-11-22 2017-05-03 The Board of Trustees of the University of Illionis Engineered high-affinity human t cell receptors
EP3137100B1 (en) 2014-04-15 2023-12-20 University Of Virginia Patent Foundation Isolated t cell receptors and methods of use therefor
EP2944652A1 (en) * 2014-05-13 2015-11-18 Technische Universität München Glypican-3-specific T-cell receptors and their uses for immunotherapy of hepatocellular carcinoma
WO2016014725A1 (en) * 2014-07-22 2016-01-28 The University Of Notre Dame Du Lac Molecular constructs and uses thereof
GB201417803D0 (en) * 2014-10-08 2014-11-19 Adaptimmune Ltd T cell receptors
GB201506642D0 (en) 2015-04-20 2015-06-03 Ucl Business Plc T cell receptor
NL2014935B1 (en) 2015-06-08 2017-02-03 Applied Immune Tech Ltd T cell receptor like antibodies having fine specificity.
GB201516277D0 (en) 2015-09-15 2015-10-28 Adaptimmune Ltd And Immunocore Ltd TCR libraries
US11827688B2 (en) 2016-06-02 2023-11-28 Immunocore Limited Dosing regimen for GP100-specific TCR—anti-CD3 SCFV fusion protein
GB201617714D0 (en) 2016-10-19 2016-11-30 Ucl Business Plc T Cell receptor
BR112019018863A8 (pt) * 2017-03-15 2023-05-02 Hutchinson Fred Cancer Res Tcrs de alta afinidade específicos para mage-a1 e usos dos mesmos
EP4327819A3 (en) * 2017-06-30 2024-05-29 Academisch Ziekenhuis Leiden (H.O.D.N. Leids Universitair Medisch Centrum) Treatment of haematological malignancies
EP3692058A1 (en) 2017-10-06 2020-08-12 Oslo Universitetssykehus HF Chimeric antigen receptors
CN112646024B (zh) * 2019-10-10 2023-03-24 香雪生命科学技术(广东)有限公司 一种识别kras突变的t细胞受体及其编码序列

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2004044004A2 (en) * 2002-11-09 2004-05-27 Avidex Limited T cell receptor display

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP4317940B2 (ja) 2001-08-31 2009-08-19 イミュノコア・リミテッド 物質
US7751825B2 (en) 2002-06-27 2010-07-06 Qualcomm Incorporated Controlling geographic location information of devices operating in wireless communication systems
US7569664B2 (en) 2002-10-09 2009-08-04 Immunocore Limited Single chain recombinant T cell receptors
EP1567553A2 (en) * 2002-12-03 2005-08-31 Avidex Ltd. Complexes of receptors
WO2005114215A2 (en) * 2004-05-19 2005-12-01 Avidex Ltd Method of improving t cell receptors
DE602005011617D1 (de) 2004-05-19 2009-01-22 Medigene Ltd Hochaffiner ny-eso-t-zellen-rezeptor

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2004044004A2 (en) * 2002-11-09 2004-05-27 Avidex Limited T cell receptor display

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
JPN6011052937; Nat. Biotechnol. 23(3), 200503, 349-54 *
JPN6011052939; J. Immunol. 161, 1998, 6956-62 *

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2018527954A (ja) * 2015-09-15 2018-09-27 アダプティミューネ リミテッドAdaptimmune Limited Tcrライブラリ

Also Published As

Publication number Publication date
AU2006253941A2 (en) 2008-03-06
EP1893642A2 (en) 2008-03-05
MX2007014919A (es) 2009-02-16
US20080292549A1 (en) 2008-11-27
WO2006129085A3 (en) 2007-02-01
CA2610786A1 (en) 2006-12-07
ZA200710009B (en) 2008-09-25
US8217144B2 (en) 2012-07-10
WO2006129085A2 (en) 2006-12-07
EA012507B1 (ru) 2009-10-30
CN101189261A (zh) 2008-05-28
AU2006253941B2 (en) 2012-04-12
CN101189261B (zh) 2012-12-05
EA200702677A1 (ru) 2008-06-30
BRPI0611326A2 (pt) 2010-08-31
GB0511124D0 (en) 2005-07-06
AU2006253941A1 (en) 2006-12-07

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