JP2008543926A - 呼吸器系に影響を及ぼす炎症状態における活性化プロテインｃの気道投与 - Google Patents
呼吸器系に影響を及ぼす炎症状態における活性化プロテインｃの気道投与 Download PDFInfo
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/55—Protease inhibitors
- A61K38/57—Protease inhibitors from animals; from humans
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/43—Enzymes; Proenzymes; Derivatives thereof
- A61K38/46—Hydrolases (3)
- A61K38/48—Hydrolases (3) acting on peptide bonds (3.4)
- A61K38/482—Serine endopeptidases (3.4.21)
- A61K38/4866—Protein C (3.4.21.69)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/007—Pulmonary tract; Aromatherapy
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/007—Pulmonary tract; Aromatherapy
- A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
- A61K9/0075—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy for inhalation via a dry powder inhaler [DPI], e.g. comprising micronized drug mixed with lactose carrier particles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/007—Pulmonary tract; Aromatherapy
- A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
- A61K9/0078—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy for inhalation via a nebulizer such as a jet nebulizer, ultrasonic nebulizer, e.g. in the form of aqueous drug solutions or dispersions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/18—Drugs for disorders of the alimentary tract or the digestive system for pancreatic disorders, e.g. pancreatic enzymes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/16—Central respiratory analeptics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Pulmonology (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Immunology (AREA)
- Gastroenterology & Hepatology (AREA)
- Otolaryngology (AREA)
- Dispersion Chemistry (AREA)
- Zoology (AREA)
- Rheumatology (AREA)
- Pain & Pain Management (AREA)
- Communicable Diseases (AREA)
- Hematology (AREA)
- Diabetes (AREA)
- Oncology (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
- Medicinal Preparation (AREA)
- Enzymes And Modification Thereof (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US69396805P | 2005-06-24 | 2005-06-24 | |
| PCT/IB2006/002773 WO2007012976A2 (en) | 2005-06-24 | 2006-06-23 | Airway administration of activated protein c in inflammatory conditions affecting the respiratory tract |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2013037700A Division JP2013151510A (ja) | 2005-06-24 | 2013-02-27 | 呼吸器系に影響を及ぼす炎症状態における活性化プロテインｃの気道投与 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2008543926A true JP2008543926A (ja) | 2008-12-04 |
| JP2008543926A5 JP2008543926A5 (https=) | 2009-08-13 |
Family
ID=37570814
Family Applications (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2008517630A Pending JP2008543926A (ja) | 2005-06-24 | 2006-06-23 | 呼吸器系に影響を及ぼす炎症状態における活性化プロテインｃの気道投与 |
| JP2008517629A Pending JP2008543925A (ja) | 2005-06-24 | 2006-06-23 | 呼吸器系に影響を及ぼす炎症状態における組織因子系凝固インヒビターの気道投与 |
| JP2013037700A Pending JP2013151510A (ja) | 2005-06-24 | 2013-02-27 | 呼吸器系に影響を及ぼす炎症状態における活性化プロテインｃの気道投与 |
Family Applications After (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2008517629A Pending JP2008543925A (ja) | 2005-06-24 | 2006-06-23 | 呼吸器系に影響を及ぼす炎症状態における組織因子系凝固インヒビターの気道投与 |
| JP2013037700A Pending JP2013151510A (ja) | 2005-06-24 | 2013-02-27 | 呼吸器系に影響を及ぼす炎症状態における活性化プロテインｃの気道投与 |
Country Status (14)
| Country | Link |
|---|---|
| US (3) | US20100279925A1 (https=) |
| EP (3) | EP1896059B1 (https=) |
| JP (3) | JP2008543926A (https=) |
| KR (2) | KR20080074085A (https=) |
| CN (2) | CN101262880A (https=) |
| AU (2) | AU2006260599A1 (https=) |
| BR (2) | BRPI0611710A2 (https=) |
| CA (2) | CA2612597C (https=) |
| DK (3) | DK1898945T3 (https=) |
| IL (2) | IL188220A0 (https=) |
| NO (2) | NO20080434L (https=) |
| RU (2) | RU2496515C2 (https=) |
| WO (3) | WO2007012976A2 (https=) |
| ZA (2) | ZA200800251B (https=) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP2101787B1 (en) * | 2006-12-11 | 2013-09-18 | Drugrecure ApS | Methods for treating cystic fibrosis or pneumonia with bacterial infection via pulmonary administration of fosfomycin |
| AU2013286812B2 (en) | 2012-07-04 | 2017-04-20 | Zz Biotech Llc | Treatment of inflammatory skin disorders |
| PT3137102T (pt) * | 2014-04-16 | 2021-09-28 | Zz Biotech Llc | Apc para utilização no tratamento de cicatrização cutânea anormal |
| PL3131572T3 (pl) | 2014-04-16 | 2022-02-07 | Zz Biotech Llc | Analog apc do zastosowania w zaleczaniu rany |
| WO2018053029A1 (en) * | 2016-09-13 | 2018-03-22 | Prothera Biologics, Inc. | Methods for treating pulmonary disease using inter-alpha inhibitor proteins |
Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2003040797A (ja) * | 2001-07-06 | 2003-02-13 | Aventis Behring Gmbh | 抗炎症性肺疾患およびａｒｄｓにおける抗トロンビン吸入のための医薬製剤 |
Family Cites Families (32)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4235871A (en) * | 1978-02-24 | 1980-11-25 | Papahadjopoulos Demetrios P | Method of encapsulating biologically active materials in lipid vesicles |
| US4501728A (en) * | 1983-01-06 | 1985-02-26 | Technology Unlimited, Inc. | Masking of liposomes from RES recognition |
| US4775624A (en) * | 1985-02-08 | 1988-10-04 | Eli Lilly And Company | Vectors and compounds for expression of human protein C |
| GR860984B (en) * | 1985-04-17 | 1986-08-18 | Zymogenetics Inc | Expression of factor vii and ix activities in mammalian cells |
| US4837028A (en) * | 1986-12-24 | 1989-06-06 | Liposome Technology, Inc. | Liposomes with enhanced circulation time |
| US4966852A (en) * | 1987-07-23 | 1990-10-30 | Monsanto Company | DNA clone of human tissue factor inhibitor |
| US5106833A (en) * | 1987-07-23 | 1992-04-21 | Washington University | Coagulation inhibitors |
| US4992373A (en) * | 1987-12-04 | 1991-02-12 | Eli Lilly And Company | Vectors and compounds for direct expression of activated human protein C |
| US6013619A (en) * | 1988-01-06 | 2000-01-11 | The Scripps Research Institute | Pulmonary surfactants and therapeutic uses, including pulmonary lavage |
| US4981952A (en) * | 1988-10-04 | 1991-01-01 | Eli Lilly And Company | Method for the purification of vitamin K-dependent proteins |
| US5378614A (en) * | 1989-08-18 | 1995-01-03 | Novo Nordisk A/S | Vector and method for making tissue factor pathway inhibitor (TFPI) analogues in yeast |
| DK408089D0 (da) * | 1989-08-18 | 1989-08-18 | Novo Nordisk As | Proteiner |
| SE9200541D0 (sv) * | 1992-02-24 | 1992-02-24 | Kabi Pharmacia Ab | New usee of omega-3-fatty acids |
| US5212091A (en) * | 1992-03-02 | 1993-05-18 | Monsanto Company | Method of producing tissue factor pathway inhibitor |
| EP0946715B1 (en) * | 1996-11-08 | 2006-03-29 | Oklahoma Medical Research Foundation | Use of a modified protein c |
| WO1998032459A1 (en) * | 1997-01-29 | 1998-07-30 | University Technology Corporation | Plasminogen activator as an anti-inflammatory agent |
| HUP0001237A3 (en) * | 1997-10-20 | 2002-01-28 | Lilly Co Eli | Methods for treating vascular disorders |
| US6049577A (en) * | 1998-05-28 | 2000-04-11 | Glenayre Electronics, Inc. | Header synchronization detector |
| AR023819A1 (es) * | 1999-05-03 | 2002-09-04 | Astrazeneca Ab | FORMULACIoN FARMACEUTICA, KIT DE PARTES Y UTILIZACION DE DICHA FORMULACION |
| JP4848092B2 (ja) * | 2000-02-01 | 2011-12-28 | 石原産業株式会社 | ジアミノトリフルオロメチルピリジン誘導体を含有する肺不全の治療剤又は予防剤 |
| WO2001057193A2 (en) * | 2000-02-02 | 2001-08-09 | Eli Lilly And Company | Protein c derivatives |
| DE60138364D1 (de) * | 2000-02-11 | 2009-05-28 | Bayer Healthcare Llc | Gerinnungsfaktor vii oder viia konjugate |
| US6933367B2 (en) * | 2000-10-18 | 2005-08-23 | Maxygen Aps | Protein C or activated protein C-like molecules |
| AU2002338487A1 (en) * | 2001-05-02 | 2002-11-11 | Novo Nordisk A/S | Modified fvii in treatment of ards |
| EP1446140A4 (en) * | 2001-10-15 | 2007-03-07 | Novartis Vaccines & Diagnostic | TREATMENT OF HEAVY PNEUMONIA BY ADMINISTRATION OF TFPI (TISSUE FACTOR PATHWAY INHIBITOR) |
| KR100674315B1 (ko) * | 2002-02-08 | 2007-01-24 | 에스케이 주식회사 | 가열로 튜브 세척제 및 세척방법 |
| WO2003090682A2 (en) * | 2002-04-25 | 2003-11-06 | The Scripps Research Institute | Treatment and prevention of pulmonary conditions |
| DE602004019761D1 (de) | 2003-01-08 | 2009-04-16 | Novartis Vaccines & Diagnostic | Stabilisierte wässrige zusammensetzungen mit gewebefaktorinhibitor (tfpi) oder gewebefaktorinhibitor-variante |
| JPWO2004087148A1 (ja) * | 2003-03-31 | 2006-06-29 | 協和醗酵工業株式会社 | 肺疾患の治療および／または予防剤 |
| WO2005042011A1 (en) * | 2003-11-04 | 2005-05-12 | Novo Nordisk A/S | Pharmaceutical composition comprising a protein c polypeptide and a blood glucose regulator |
| DK1791555T3 (da) * | 2004-09-10 | 2013-06-10 | Pharmaorigin Aps | Fremgangsmåde til behandling af lokal tracheal, bronchial eller alveolær blødning eller hæmoptyse |
| US8563511B2 (en) | 2004-10-06 | 2013-10-22 | University Of Rochester | Treatment of pulmonary hypertension using an agent that inhibits a tissue factor pathway |
-
2006
- 2006-06-23 ZA ZA200800251A patent/ZA200800251B/xx unknown
- 2006-06-23 CN CNA2006800310726A patent/CN101262880A/zh active Pending
- 2006-06-23 US US11/993,264 patent/US20100279925A1/en not_active Abandoned
- 2006-06-23 ZA ZA200800255A patent/ZA200800255B/xx unknown
- 2006-06-23 CN CN2006800310622A patent/CN101262879B/zh not_active Expired - Fee Related
- 2006-06-23 DK DK06795540.1T patent/DK1898945T3/da active
- 2006-06-23 KR KR1020087001975A patent/KR20080074085A/ko not_active Withdrawn
- 2006-06-23 EP EP06795527A patent/EP1896059B1/en active Active
- 2006-06-23 BR BRPI0611710-4A patent/BRPI0611710A2/pt not_active Application Discontinuation
- 2006-06-23 AU AU2006260599A patent/AU2006260599A1/en not_active Abandoned
- 2006-06-23 WO PCT/IB2006/002773 patent/WO2007012976A2/en not_active Ceased
- 2006-06-23 CA CA2612597A patent/CA2612597C/en not_active Expired - Fee Related
- 2006-06-23 AU AU2006273696A patent/AU2006273696B2/en not_active Ceased
- 2006-06-23 JP JP2008517630A patent/JP2008543926A/ja active Pending
- 2006-06-23 DK DK06795527.8T patent/DK1896059T3/da active
- 2006-06-23 DK DK06808954.9T patent/DK1906994T3/da active
- 2006-06-23 US US11/993,253 patent/US8088728B2/en not_active Expired - Fee Related
- 2006-06-23 US US11/993,256 patent/US20100297099A1/en not_active Abandoned
- 2006-06-23 WO PCT/IB2006/002631 patent/WO2006136963A2/en not_active Ceased
- 2006-06-23 BR BRPI0613137-9A patent/BRPI0613137A2/pt not_active Application Discontinuation
- 2006-06-23 RU RU2008102656/15A patent/RU2496515C2/ru not_active IP Right Cessation
- 2006-06-23 EP EP06808954.9A patent/EP1906994B1/en active Active
- 2006-06-23 WO PCT/IB2006/002602 patent/WO2006136962A2/en not_active Ceased
- 2006-06-23 EP EP06795540A patent/EP1898945B1/en active Active
- 2006-06-23 KR KR1020087001976A patent/KR20080071116A/ko not_active Withdrawn
- 2006-06-23 JP JP2008517629A patent/JP2008543925A/ja active Pending
- 2006-06-23 RU RU2008102655/15A patent/RU2496516C2/ru not_active IP Right Cessation
- 2006-06-23 CA CA2612646A patent/CA2612646C/en not_active Expired - Fee Related
-
2007
- 2007-12-18 IL IL188220A patent/IL188220A0/en unknown
- 2007-12-18 IL IL188221A patent/IL188221A0/en unknown
-
2008
- 2008-01-23 NO NO20080434A patent/NO20080434L/no unknown
- 2008-01-23 NO NO20080433A patent/NO20080433L/no unknown
-
2013
- 2013-02-27 JP JP2013037700A patent/JP2013151510A/ja active Pending
Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2003040797A (ja) * | 2001-07-06 | 2003-02-13 | Aventis Behring Gmbh | 抗炎症性肺疾患およびａｒｄｓにおける抗トロンビン吸入のための医薬製剤 |
Non-Patent Citations (1)
| Title |
|---|
| JPN6011058396; 篠崎正博: '治療の展開 『呼吸・循環管理』' 日本臨床 Ｖｏｌ．６２，Ｎｏ．１２, 200412, Ｐ．２３０１-２３０７ * |
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