JP2008538315A5 - - Google Patents
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- JP2008538315A5 JP2008538315A5 JP2008507714A JP2008507714A JP2008538315A5 JP 2008538315 A5 JP2008538315 A5 JP 2008538315A5 JP 2008507714 A JP2008507714 A JP 2008507714A JP 2008507714 A JP2008507714 A JP 2008507714A JP 2008538315 A5 JP2008538315 A5 JP 2008538315A5
- Authority
- JP
- Japan
- Prior art keywords
- agent
- invasive
- implant
- disc
- arthrogenic
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
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- 230000001740 anti-invasion Effects 0.000 claims 21
- 239000003795 chemical substances by application Substances 0.000 claims 20
- 239000007943 implant Substances 0.000 claims 13
- 150000001875 compounds Chemical class 0.000 claims 6
- 239000003814 drug Substances 0.000 claims 4
- 229940079593 drugs Drugs 0.000 claims 4
- 238000002513 implantation Methods 0.000 claims 4
- 230000002188 osteogenic Effects 0.000 claims 4
- 239000003242 anti bacterial agent Substances 0.000 claims 2
- 230000000181 anti-adherence Effects 0.000 claims 2
- 239000002260 anti-inflammatory agent Substances 0.000 claims 2
- 239000004599 antimicrobial Substances 0.000 claims 2
- 239000006260 foam Substances 0.000 claims 2
- 230000002439 hemostatic Effects 0.000 claims 2
- 230000002401 inhibitory effect Effects 0.000 claims 2
- 239000000463 material Substances 0.000 claims 2
- 239000000203 mixture Substances 0.000 claims 2
- 230000002138 osteoinductive Effects 0.000 claims 2
- 239000000843 powder Substances 0.000 claims 2
- 239000010409 thin film Substances 0.000 claims 2
- 210000001519 tissues Anatomy 0.000 claims 2
- 230000003444 anaesthetic Effects 0.000 claims 1
- 230000000202 analgesic Effects 0.000 claims 1
- 239000000730 antalgic agent Substances 0.000 claims 1
- 229940121363 anti-inflammatory agents Drugs 0.000 claims 1
- 230000000259 anti-tumor Effects 0.000 claims 1
- 239000011248 coating agent Substances 0.000 claims 1
- 238000000576 coating method Methods 0.000 claims 1
- 239000000499 gel Substances 0.000 claims 1
- 239000003193 general anesthetic agent Substances 0.000 claims 1
- 239000000243 solution Substances 0.000 claims 1
Claims (19)
- 関節形成性人工円板の運動能力を保存する植込物であって、関節形成性表面および非関節形成性表面を有する人工デバイスを含み、ここにおいて、少なくとも一つの非関節形成性表面は、非関節形成性の植込物−骨界面を含み、そしてここにおいて、抗浸潤薬を、関節形成性表面上に塗布している、または関節形成性表面中に包含している植込物。
- 抗浸潤薬が、止血性化合物、抗癒着薬、一時的空間占有性バリア材料、骨形成阻害性化合物およびいずれかそれらの組合せから成る群より選択される、請求項１に記載の植込物。
- 抗炎症薬、鎮痛薬、麻酔薬、抗微生物薬および／または抗細菌薬の少なくとも一つを更に含む、請求項１または２に記載の植込物。
- 人工円板の植込物−骨界面の非関節形成性表面に、骨形成性または骨誘導性の少なくとも一つの化合物を更に含む、請求項１乃至３のいずれか１項に記載の植込物。
- 抗浸潤薬が、ゲル、薄膜、溶液、泡状物、海綿状物または粉末として製剤化されている、請求項１乃至４のいずれか１項に記載の植込物。
- 抗浸潤薬が関節形成性表面へ適用されたときに、人工円板の植込物−骨界面の非関節形成性表面における所望の組織成長を妨害しない、請求項１乃至５のいずれか１項に記載の植込物。
- 抗浸潤薬が、生体再吸収性（bioresorbable）である、請求項１乃至６のいずれか１項に記載の植込物。
- 植込物が患者の体内に植込まれたときに植込物内での運動能力を保存するための、請求項１乃至７のいずれか１項に記載の植込物の使用。
- 患者への人工円板の植込み前に、抗浸潤薬を、該円板の関節形成性表面上にコーティングとして適用する、または該表面中に包含させる、請求項１乃至７のいずれか１項に記載の植込物の使用。
- 患者への人工円板の外科的植込みの際に、抗浸潤薬を、該円板の関節形成性表面上またはその周囲に適用する、請求項１乃至７記載のいずれか１項に記載の植込物の使用。
- 関節形成性人工円板の運動能力を保存するための、関節形成性人工円板の関節形成性表面に適用された抗浸潤薬の使用。
- 抗浸潤薬が、止血性化合物、抗癒着薬、一時的空間占有性バリア材料、骨形成阻害性化合物およびいずれかそれらの組合せから成る群より選択される、請求項１１に記載の抗浸潤薬の使用。
- 抗炎症薬、鎮痛薬、麻酔薬、抗微生物薬および／または抗細菌薬の少なくとも一つを更に含む、請求項１１または１２に記載の抗浸潤薬の使用。
- 人工円板の植込物−骨界面の非関節形成性表面に適用された骨形成性または骨誘導性の化合物を少なくとも一つ更に含む、請求項１１乃至１３のいずれか１項に記載の抗浸潤薬の使用。
- 抗浸潤薬が、ゲル、薄膜、溶液、泡状物、海綿状物または粉末として製剤化されている、請求項１１乃至１４のいずれか１項に記載の抗浸潤薬の使用。
- 関節形成性表面への抗浸潤薬の適用が、人工円板の植込物−骨界面の非関節形成性表面における所望の組織成長を妨害しない、請求項１１乃至１５のいずれか１項に記載の抗浸潤薬の使用。
- 抗浸潤薬が、生体再吸収性（bioresorbable）である、請求項１１乃至１６のいずれか１項に記載の抗浸潤薬の使用。
- 患者への人工円板の植込み前に、抗浸潤薬が該円板の関節形成性表面上に塗布されるか、または該表面中に包含される、請求項１１乃至１７のいずれか１項に記載の抗浸潤薬の使用。
- 患者への人工円板の外科的植込みの際に、抗浸潤薬が該円板の関節形成性表面上またはその周囲に適用される、請求項１１乃至１７のいずれか１項に記載の抗浸潤薬の使用。
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US11/104,297 US8257438B2 (en) | 2005-04-12 | 2005-04-12 | Methods and devices for preserving motion in an articulating prosthetic disc |
| PCT/US2006/013571 WO2006113249A2 (en) | 2005-04-12 | 2006-04-11 | Methods and devices for preserving motion in an articulating prosthetic disc |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2008538315A JP2008538315A (ja) | 2008-10-23 |
| JP2008538315A5 true JP2008538315A5 (ja) | 2009-03-19 |
Family
ID=37084088
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2008507714A Pending JP2008538315A (ja) | 2005-04-12 | 2006-04-11 | 関節形成性人工円板の運動能力を保存する方法およびデバイス |
Country Status (6)
| Country | Link |
|---|---|
| US (1) | US8257438B2 (ja) |
| EP (1) | EP1874368A2 (ja) |
| JP (1) | JP2008538315A (ja) |
| AU (1) | AU2006236849B2 (ja) |
| CA (1) | CA2604921A1 (ja) |
| WO (1) | WO2006113249A2 (ja) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US8092541B2 (en) | 2007-08-03 | 2012-01-10 | Warsaw Orthopedic, Inc. | Method of using an anti-growth matrix as a barrier for cell attachment and osteo-inductive factors |
| US9402863B2 (en) * | 2010-03-05 | 2016-08-02 | Endosat Nv | Methods and systems for conditioning in surgery |
Family Cites Families (28)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US1524528A (en) | 1922-09-23 | 1925-01-27 | Niles Bement Pond Co | Boring and facing machine |
| US5068225A (en) * | 1987-05-04 | 1991-11-26 | Mdr Group, Inc. | Viscoelastic fluid for use in surgery and other therapies and method of using same |
| US5702448A (en) * | 1990-09-17 | 1997-12-30 | Buechel; Frederick F. | Prosthesis with biologically inert wear resistant surface |
| US5192326A (en) * | 1990-12-21 | 1993-03-09 | Pfizer Hospital Products Group, Inc. | Hydrogel bead intervertebral disc nucleus |
| JP3007903B2 (ja) * | 1991-03-29 | 2000-02-14 | 京セラ株式会社 | 人工椎間板 |
| US5605938A (en) | 1991-05-31 | 1997-02-25 | Gliatech, Inc. | Methods and compositions for inhibition of cell invasion and fibrosis using dextran sulfate |
| JPH06135976A (ja) * | 1992-10-30 | 1994-05-17 | Toray Ind Inc | メタンジホスホン酸誘導体、その製造方法およびその医薬用途 |
| JPH0776523A (ja) * | 1993-07-21 | 1995-03-20 | Dai Ichi Seiyaku Co Ltd | 異所性骨化症予防・治療薬 |
| CA2142634C (en) * | 1994-02-18 | 2005-09-20 | Salvatore Caldarise | Self-lubricating implantable articulation member |
| JPH08176191A (ja) * | 1994-07-04 | 1996-07-09 | Hoechst Japan Ltd | 合成ペプチド誘導体または、その塩 |
| US20040111159A1 (en) * | 2000-01-30 | 2004-06-10 | Diamicron, Inc. | Modular bearing surfaces in prosthetic joints |
| US5846770A (en) | 1994-11-22 | 1998-12-08 | Genetics Institute, Inc. | DNA molecules encoding human chordin |
| US5811151A (en) | 1996-05-31 | 1998-09-22 | Medtronic, Inc. | Method of modifying the surface of a medical device |
| US6063061A (en) * | 1996-08-27 | 2000-05-16 | Fusion Medical Technologies, Inc. | Fragmented polymeric compositions and methods for their use |
| US6316522B1 (en) * | 1997-08-18 | 2001-11-13 | Scimed Life Systems, Inc. | Bioresorbable hydrogel compositions for implantable prostheses |
| JP2000119192A (ja) * | 1998-10-09 | 2000-04-25 | Aventis Pharma Ltd | 骨誘導因子アンタゴニスト活性を有する成熟型蛋白質 |
| AU3724900A (en) * | 1999-03-05 | 2000-09-21 | Louis R. Matson | Surface-modified bioactive surgical implants suppressing tissue growth |
| CA2376210A1 (en) | 1999-06-08 | 2000-12-14 | Lorantis Limited | Therapeutic use of an inhibitor of a hedgehog or a hedgehog-related signalling pathway |
| WO2002030446A2 (en) | 2000-10-13 | 2002-04-18 | Baxter International Inc. | Reduction or prevention of post-surgical adhesion formation with fibrinogen |
| US20020107185A1 (en) | 2000-12-09 | 2002-08-08 | Spencer E Martin | Human fibrotic responses to surgery and methods of treatment |
| US7182784B2 (en) | 2001-07-18 | 2007-02-27 | Smith & Nephew, Inc. | Prosthetic devices employing oxidized zirconium and other abrasion resistant surfaces contacting surfaces of cross-linked polyethylene |
| US7025787B2 (en) * | 2001-11-26 | 2006-04-11 | Sdgi Holdings, Inc. | Implantable joint prosthesis and associated instrumentation |
| US7156876B2 (en) * | 2002-10-09 | 2007-01-02 | Depuy Acromed, Inc. | Intervertebral motion disc having articulation and shock absorption |
| US6994727B2 (en) * | 2002-12-17 | 2006-02-07 | Amedica Corporation | Total disc implant |
| US7575599B2 (en) * | 2004-07-30 | 2009-08-18 | Spinalmotion, Inc. | Intervertebral prosthetic disc with metallic core |
| WO2005020955A1 (en) | 2003-09-03 | 2005-03-10 | Cell Center Cologne Gmbh | Compositions for preventing scars and fibrosis after injury or surgery |
| US20050074453A1 (en) | 2003-10-02 | 2005-04-07 | Ferree Bret A. | Methods of preventing adhesions following laminectomies and other surgical procedures |
| GB2410189A (en) * | 2004-01-23 | 2005-07-27 | Corin Ltd | Intervertebral disc prosthesis |
-
2005
- 2005-04-12 US US11/104,297 patent/US8257438B2/en active Active
-
2006
- 2006-04-11 EP EP06749824A patent/EP1874368A2/en not_active Withdrawn
- 2006-04-11 JP JP2008507714A patent/JP2008538315A/ja active Pending
- 2006-04-11 CA CA002604921A patent/CA2604921A1/en not_active Abandoned
- 2006-04-11 WO PCT/US2006/013571 patent/WO2006113249A2/en active Application Filing
- 2006-04-11 AU AU2006236849A patent/AU2006236849B2/en not_active Ceased
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