JP2008536920A5 - - Google Patents
Download PDFInfo
- Publication number
- JP2008536920A5 JP2008536920A5 JP2008507693A JP2008507693A JP2008536920A5 JP 2008536920 A5 JP2008536920 A5 JP 2008536920A5 JP 2008507693 A JP2008507693 A JP 2008507693A JP 2008507693 A JP2008507693 A JP 2008507693A JP 2008536920 A5 JP2008536920 A5 JP 2008536920A5
- Authority
- JP
- Japan
- Prior art keywords
- autoantibody
- oxidizing agent
- autoantibodies
- fluid
- composition
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 238000000034 method Methods 0.000 claims 27
- 239000007800 oxidant agent Substances 0.000 claims 17
- 239000012530 fluid Substances 0.000 claims 10
- 235000013336 milk Nutrition 0.000 claims 9
- 239000008267 milk Substances 0.000 claims 9
- 210000004080 milk Anatomy 0.000 claims 9
- 239000000427 antigen Substances 0.000 claims 8
- 102000036639 antigens Human genes 0.000 claims 8
- 108091007433 antigens Proteins 0.000 claims 8
- 239000000203 mixture Substances 0.000 claims 8
- 239000013060 biological fluid Substances 0.000 claims 5
- 230000001590 oxidative effect Effects 0.000 claims 5
- 150000001923 cyclic compounds Chemical group 0.000 claims 4
- 125000001493 tyrosinyl group Chemical group [H]OC1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C([H])(N([H])[H])C(*)=O 0.000 claims 4
- XEEYBQQBJWHFJM-UHFFFAOYSA-N Iron Chemical group [Fe] XEEYBQQBJWHFJM-UHFFFAOYSA-N 0.000 claims 3
- 241000872931 Myoporum sandwicense Species 0.000 claims 2
- 230000003429 anti-cardiolipin effect Effects 0.000 claims 2
- 229930002875 chlorophyll Natural products 0.000 claims 2
- 235000019804 chlorophyll Nutrition 0.000 claims 2
- ATNHDLDRLWWWCB-AENOIHSZSA-M chlorophyll a Chemical group C1([C@@H](C(=O)OC)C(=O)C2=C3C)=C2N2C3=CC(C(CC)=C3C)=[N+]4C3=CC3=C(C=C)C(C)=C5N3[Mg-2]42[N+]2=C1[C@@H](CCC(=O)OC\C=C(/C)CCC[C@H](C)CCC[C@H](C)CCCC(C)C)[C@H](C)C2=C5 ATNHDLDRLWWWCB-AENOIHSZSA-M 0.000 claims 2
- BTIJJDXEELBZFS-QDUVMHSLSA-K hemin Chemical group CC1=C(CCC(O)=O)C(C=C2C(CCC(O)=O)=C(C)\C(N2[Fe](Cl)N23)=C\4)=N\C1=C/C2=C(C)C(C=C)=C3\C=C/1C(C)=C(C=C)C/4=N\1 BTIJJDXEELBZFS-QDUVMHSLSA-K 0.000 claims 2
- 229940025294 hemin Drugs 0.000 claims 2
- 229910052742 iron Inorganic materials 0.000 claims 2
- 239000003446 ligand Substances 0.000 claims 2
- 229910052751 metal Inorganic materials 0.000 claims 2
- 239000002184 metal Substances 0.000 claims 2
- 230000002441 reversible effect Effects 0.000 claims 2
- OUYCCCASQSFEME-UHFFFAOYSA-N tyrosine Natural products OC(=O)C(N)CC1=CC=C(O)C=C1 OUYCCCASQSFEME-UHFFFAOYSA-N 0.000 claims 2
- OUYCCCASQSFEME-QMMMGPOBSA-N L-tyrosine Chemical compound OC(=O)[C@@H](N)CC1=CC=C(O)C=C1 OUYCCCASQSFEME-QMMMGPOBSA-N 0.000 claims 1
- 238000003556 assay Methods 0.000 claims 1
- 230000009635 nitrosylation Effects 0.000 claims 1
- 230000001737 promoting effect Effects 0.000 claims 1
- 235000020185 raw untreated milk Nutrition 0.000 claims 1
- 238000000926 separation method Methods 0.000 claims 1
Images
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US11/108,826 US9557325B2 (en) | 2003-06-09 | 2005-04-19 | Method of altering the binding specificity of proteins by oxidation-reduction reactions |
| PCT/US2006/012802 WO2006113139A2 (en) | 2005-04-19 | 2006-04-06 | Method of altering the binding specificity of proteins by oxidation-reduction reactions |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2008536920A JP2008536920A (ja) | 2008-09-11 |
| JP2008536920A5 true JP2008536920A5 (enExample) | 2011-03-31 |
Family
ID=37115646
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2008507693A Pending JP2008536920A (ja) | 2005-04-19 | 2006-04-06 | 酸化還元反応によるタンパク質の結合特異性の改変方法 |
Country Status (9)
| Country | Link |
|---|---|
| US (1) | US9557325B2 (enExample) |
| EP (1) | EP1871171A4 (enExample) |
| JP (1) | JP2008536920A (enExample) |
| CN (1) | CN101262774A (enExample) |
| AU (1) | AU2006236928B2 (enExample) |
| BR (1) | BRPI0608373A2 (enExample) |
| CA (1) | CA2602635C (enExample) |
| MX (1) | MX2007013171A (enExample) |
| WO (1) | WO2006113139A2 (enExample) |
Families Citing this family (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP4662557B2 (ja) * | 2003-06-09 | 2011-03-30 | レドックス−リアクティブ リエイジェンツ リミテッド ライアビリティー カンパニー | 酸化還元反応による血漿タンパク質の結合特異性の改変方法 |
| US7892751B2 (en) * | 2003-06-09 | 2011-02-22 | Redox-Reactive Reagents Llc | Method of detecting or diagnosing of a neurodegenerative disease or condition |
| AU2005299716B2 (en) * | 2004-10-22 | 2012-09-06 | Amgen Inc. | Methods for refolding of recombinant antibodies |
| EP2150260A2 (en) * | 2007-04-05 | 2010-02-10 | Phrixus Pharmaceuticals, Inc. | Compositions and methods for the treatment of heart failure |
| MX2010002683A (es) * | 2007-09-14 | 2010-03-26 | Amgen Inc | Poblaciones de anticuerpos homogeneos. |
| US7989596B2 (en) * | 2007-09-19 | 2011-08-02 | Redox-Reactive Reagents Llc | Method of altering the binding specificity of monoclonal antibodies by oxidation-reduction reactions |
| AU2009289520B2 (en) * | 2008-09-04 | 2013-09-12 | Redox-Reactive Reagents, Llc | Biomarkers, kits, and method for diagnosing, monitoring, and/or staging Alzheimer's disease |
| US20120107841A1 (en) * | 2010-07-19 | 2012-05-03 | Mcintyre John A | Serum Diagnostic Method, Biomarker and Kit for Early Detection and Staging of Alzheimer's Disease |
| JP2012046470A (ja) * | 2010-08-30 | 2012-03-08 | Japan Science & Technology Agency | Ｇａｐｄｈの酵素活性阻害剤 |
| CN102818896B (zh) * | 2011-06-09 | 2014-12-17 | 北京华大蛋白质研发中心有限公司 | 一种基于特异抗体的硝基化修饰位点的检测方法及特异识别scot硝基化位点的抗体 |
| ES2684976T3 (es) | 2012-04-13 | 2018-10-05 | Diabetomics, Inc. | Biomarcadores maternos para diabetes gestacional |
| WO2016081413A1 (en) * | 2014-11-17 | 2016-05-26 | The Rockefeller University | Compositions and methods for use in diagnosis of alzheimer's disease |
| ES2748117T3 (es) * | 2015-04-22 | 2020-03-13 | Euroimmun Medizinische Labordiagnostika Ag | Diagnóstico de una nueva enfermedad autoinmune |
| JP7523039B2 (ja) * | 2019-05-29 | 2024-07-26 | パナソニックＩｐマネジメント株式会社 | 検出方法及び検出装置 |
| KR102576252B1 (ko) * | 2021-04-07 | 2023-09-11 | 아주대학교산학협력단 | 산화된 면역글로불린을 유효성분으로 포함하는 면역조절 기능 이상 관련 질환 예방 또는 치료용 약학적 조성물 |
| CN118526489B (zh) * | 2024-05-24 | 2025-04-01 | 南通大学 | 一种脱镁叶绿酸乙酯的用途 |
Family Cites Families (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4703001A (en) * | 1985-10-23 | 1987-10-27 | Synbiotics, Corporation | Immunoassay for the detection of serum analytes using pH dependent chastropic acids |
| US4950612A (en) | 1987-12-16 | 1990-08-21 | Microgenics Corporation | Peroxy acid pretreatment in vitamin B12 assay |
| US5061790A (en) * | 1989-07-10 | 1991-10-29 | Molecular Diagnostics, Inc. | Oxidative denaturation of protein analytes |
| US5980954A (en) * | 1992-02-07 | 1999-11-09 | Vasogen Ireland Limited | Treatment of autoimmune diseases |
| US6660267B1 (en) * | 1992-12-21 | 2003-12-09 | Promega Corporation | Prevention and treatment of sepsis |
| AU703814B2 (en) | 1995-12-04 | 1999-04-01 | Wyeth | Antioxidant |
| US5939394A (en) * | 1996-01-18 | 1999-08-17 | Fleming & Company | Methods and compositions for the prevention and treatment of immunological disorders, inflammatory diseases and infections |
| FR2794461B1 (fr) | 1999-06-07 | 2004-01-23 | Lab Francais Du Fractionnement | Procede de preparation de nouvelles fractions d'ig humaines possedant une activite immunomodulatrice |
| FR2822238B1 (fr) * | 2001-03-16 | 2003-08-29 | Gemac | Methode et trousse pour le suivi des maladies neurodegeneratives |
| US7892751B2 (en) * | 2003-06-09 | 2011-02-22 | Redox-Reactive Reagents Llc | Method of detecting or diagnosing of a neurodegenerative disease or condition |
| JP4662557B2 (ja) | 2003-06-09 | 2011-03-30 | レドックス−リアクティブ リエイジェンツ リミテッド ライアビリティー カンパニー | 酸化還元反応による血漿タンパク質の結合特異性の改変方法 |
-
2005
- 2005-04-19 US US11/108,826 patent/US9557325B2/en not_active Expired - Fee Related
-
2006
- 2006-04-06 WO PCT/US2006/012802 patent/WO2006113139A2/en not_active Ceased
- 2006-04-06 AU AU2006236928A patent/AU2006236928B2/en not_active Ceased
- 2006-04-06 JP JP2008507693A patent/JP2008536920A/ja active Pending
- 2006-04-06 CA CA2602635A patent/CA2602635C/en not_active Expired - Fee Related
- 2006-04-06 EP EP06749407.0A patent/EP1871171A4/en not_active Withdrawn
- 2006-04-06 CN CNA2006800133026A patent/CN101262774A/zh active Pending
- 2006-04-06 BR BRPI0608373-0A patent/BRPI0608373A2/pt not_active Application Discontinuation
- 2006-04-06 MX MX2007013171A patent/MX2007013171A/es active IP Right Grant
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| JP2008536920A5 (enExample) | ||
| JP2006526027A5 (enExample) | ||
| Anderson et al. | Oriented immobilization of single-domain antibodies using SpyTag/SpyCatcher yields improved limits of detection | |
| Verma et al. | Liquid crystal based detection of Pb (II) ions using spinach RNA as recognition probe | |
| Kaur et al. | Bridged Rebar Graphene functionalized aptasensor for pathogenic E. coli O78: K80: H11 detection | |
| Dodev et al. | Inhibition of allergen‐dependent IgE activity by antibodies of the same specificity but different class | |
| Wang et al. | Isoelectric bovine serum albumin: robust blocking agent for enhanced performance in optical-fiber based DNA sensing | |
| Langston et al. | Action of CMG with strand-specific DNA blocks supports an internal unwinding mode for the eukaryotic replicative helicase | |
| JP2009531694A5 (enExample) | ||
| JP2011524740A5 (enExample) | ||
| Zhang et al. | Selection of a new Mycobacterium tuberculosis H37Rv aptamer and its application in the construction of a SWCNT/aptamer/Au-IDE MSPQC H37Rv sensor | |
| Eifler et al. | Development of a novel affinity chromatography resin for platform purification of lambda fabs | |
| IL184103A (en) | Synthetic immunoglobulin domains with binding properties engineered in regions of the molecule different from the complementarity determining regions | |
| Henry et al. | Identification of cross-reactive single-domain antibodies against serum albumin using next-generation DNA sequencing | |
| Krepper et al. | Temperature dependence of antibody adsorption in protein A affinity chromatography | |
| Liu et al. | Chemiluminescence detection of protein in capillary electrophoresis using aptamer-functionalized gold nanoparticles as biosensing platform | |
| WO2008008553A3 (en) | Genetic polymorphisms associated with alzheimer's disease, methods of detection and uses thereof | |
| WO2008020823A3 (en) | Cooperative reporter systems, components, and methods for analyte detection | |
| Palau et al. | Simulated single-cycle kinetics improves the design of surface plasmon resonance assays | |
| WO2012099949A3 (en) | Antibody purification via affinity chromatography | |
| Henry et al. | Formation and fate of oil-related aggregates (ORAs) in seawater at different temperatures | |
| Hanna et al. | Sorption of two naphthoic acids to goethite surface under flow through conditions | |
| WO2014081278A1 (en) | (method for detection of target analyte(s) | |
| Polonska et al. | Azocontaining polymers, in situ immobilized on the silica gel surface | |
| Yu et al. | Quantitative evaluation of biological reaction kinetics in confined nanospaces |