JP2008536815A - チオエーテル架橋を含む巨大分子 - Google Patents

チオエーテル架橋を含む巨大分子 Download PDF

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Publication number
JP2008536815A
JP2008536815A JP2008501999A JP2008501999A JP2008536815A JP 2008536815 A JP2008536815 A JP 2008536815A JP 2008501999 A JP2008501999 A JP 2008501999A JP 2008501999 A JP2008501999 A JP 2008501999A JP 2008536815 A JP2008536815 A JP 2008536815A
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JP
Japan
Prior art keywords
antibody
composition
antibodies
thioether
thioether bridge
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Abandoned
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JP2008501999A
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English (en)
Japanese (ja)
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JP2008536815A5 (https=
Inventor
アイ． トウス グイルレルモ
スチェネルマン マルク
ウェイ ジピング
Original Assignee
メディミューン，エルエルシー
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Application filed by メディミューン，エルエルシー filed Critical メディミューン，エルエルシー
Publication of JP2008536815A publication Critical patent/JP2008536815A/ja
Publication of JP2008536815A5 publication Critical patent/JP2008536815A5/ja
Abandoned legal-status Critical Current

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/08—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from viruses
    • C07K16/10—RNA viruses
    • C07K16/11—Paramyxoviridae (F); Pneumoviridae (F), e.g. respiratory syncytial virus [RSV]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/24—Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/52—Constant or Fc region; Isotype
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/60—Immunoglobulins specific features characterized by non-natural combinations of immunoglobulin fragments
    • C07K2317/62—Immunoglobulins specific features characterized by non-natural combinations of immunoglobulin fragments comprising only variable region components
    • C07K2317/624—Disulfide-stabilized antibody (dsFv)

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Immunology (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Virology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
JP2008501999A 2005-03-14 2006-03-14 チオエーテル架橋を含む巨大分子 Abandoned JP2008536815A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US66172405P 2005-03-14 2005-03-14
US69913805P 2005-07-13 2005-07-13
PCT/US2006/009311 WO2006099481A2 (en) 2005-03-14 2006-03-14 Macromolecules comprising a thioether cross-link

Publications (2)

Publication Number Publication Date
JP2008536815A true JP2008536815A (ja) 2008-09-11
JP2008536815A5 JP2008536815A5 (https=) 2009-05-21

Family

ID=36992404

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2008501999A Abandoned JP2008536815A (ja) 2005-03-14 2006-03-14 チオエーテル架橋を含む巨大分子

Country Status (6)

Country Link
US (2) US20090030187A1 (https=)
EP (1) EP1858911A4 (https=)
JP (1) JP2008536815A (https=)
AU (1) AU2006223002A1 (https=)
CA (1) CA2600844A1 (https=)
WO (1) WO2006099481A2 (https=)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2019509483A (ja) * 2016-02-25 2019-04-04 ザ バインディング サイト グループ リミティド 質量分析キット

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2007245164A1 (en) * 2006-03-28 2007-11-08 Biogen Idec Ma Inc. Anti-IGF-IR antibodies and uses thereof
KR20100052545A (ko) * 2007-08-28 2010-05-19 바이오겐 아이덱 엠에이 인코포레이티드 Ｉｇｆ―１ｒ의 다중 에피토프에 결합하는 조성물
CA2697612A1 (en) * 2007-08-28 2009-03-12 Biogen Idec Ma Inc. Anti-igf-1r antibodies and uses thereof
BRPI0816094A2 (pt) 2007-08-30 2015-03-03 Daiichi Sankyo Co Ltd Anticorpo, polipeptídeo, hibridoma, composição farmacêutica, método para inibir o desenvolvimento de tumor em um mamífero, polinucleotídeo, célula hospedeira, e, método para produzir um anticorpo.
JP5615181B2 (ja) 2007-11-27 2014-10-29 ザ・ユニバーシティ・オブ・ブリティッシュ・コロンビア 関節炎の予防及び治療のための組成物及び方法
CN102065895A (zh) * 2008-04-11 2011-05-18 比奥根艾迪克Ma公司 抗-igf-1r抗体和其它化合物的治疗联合
AU2013337346A1 (en) * 2012-11-05 2015-05-14 Medimmune, Llc Method of isolating Synagis in the absence of benzonase
BR112017008383A2 (en) * 2014-10-31 2018-07-31 Medimmune, Llc improved production method
EP3420362B1 (en) * 2016-02-25 2023-03-22 The Binding Site Group Limited Antibodies
US11479600B2 (en) 2016-10-21 2022-10-25 Adimab, Llc Anti-respiratory syncytial virus antibodies, and methods of their generation and use
AU2017345786B2 (en) 2016-10-21 2024-08-01 Adimab, Llc Anti-respiratory syncytial virus antibodies, and methods of their generation and use
CN110035771B (zh) 2016-10-21 2024-03-08 阿迪马布有限责任公司 抗呼吸道合胞病毒抗体及其产生和使用方法
GB201708262D0 (en) 2017-05-23 2017-07-05 Binding Site Group Ltd Assay for plasma cell associated disease
CN108017717B (zh) * 2018-01-24 2019-08-16 首都医科大学宣武医院 一种用于体外高效定向扩增的嵌合抗原受体及其应用
JP7842564B2 (ja) * 2018-09-21 2026-04-08 ザ ユニバーシティ オブ ノース カロライナ アット チャペル ヒル 粘液を透過するのを制限するための合成結合剤
GB202007047D0 (en) 2020-05-13 2020-06-24 Binding Site Group Ltd Mass spectrometry controls
WO2022175728A1 (en) * 2021-02-19 2022-08-25 Waters Technologies Corporation Methods for peptide mapping of adeno-associated virus (aav) proteins
WO2025104604A1 (en) 2023-11-14 2025-05-22 Janssen Pharmaceuticals, Inc. Anti-respiratory syncytial virus antibodies and uses thereof

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1991003493A1 (en) 1989-08-29 1991-03-21 The University Of Southampton Bi-or trispecific (fab)3 or (fab)4 conjugates
US5091542A (en) 1990-03-09 1992-02-25 Hybritech Incorporated Tris-maleimido compounds as intermediates in trifunctional antibody synthesis
EP0597997B1 (en) * 1991-08-09 1998-05-20 KOLBECK, Winfried Lanthionine bridged peptides
US6897044B1 (en) 1999-01-28 2005-05-24 Biogen Idec, Inc. Production of tetravalent antibodies
KR100699059B1 (ko) * 1999-04-23 2007-03-23 미쯔비시 가가꾸 가부시끼가이샤 항체 및 폴리알킬렌글리콜 결합 리포좀
US20060123504A1 (en) * 2004-12-07 2006-06-08 Avigenics, Inc. Methods of producing polyclonal antibodies
US20060286548A1 (en) * 2005-06-16 2006-12-21 Gregory Liposky Method of making recombinant human antibodies for use in biosensor technology

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2019509483A (ja) * 2016-02-25 2019-04-04 ザ バインディング サイト グループ リミティド 質量分析キット

Also Published As

Publication number Publication date
EP1858911A4 (en) 2009-12-16
US20090030187A1 (en) 2009-01-29
WO2006099481A2 (en) 2006-09-21
WO2006099481A3 (en) 2007-04-19
US7786273B2 (en) 2010-08-31
EP1858911A2 (en) 2007-11-28
US20060216284A1 (en) 2006-09-28
CA2600844A1 (en) 2006-09-21
AU2006223002A1 (en) 2006-09-21

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