JP2008535927A5 - - Google Patents
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- Publication number
- JP2008535927A5 JP2008535927A5 JP2008506677A JP2008506677A JP2008535927A5 JP 2008535927 A5 JP2008535927 A5 JP 2008535927A5 JP 2008506677 A JP2008506677 A JP 2008506677A JP 2008506677 A JP2008506677 A JP 2008506677A JP 2008535927 A5 JP2008535927 A5 JP 2008535927A5
- Authority
- JP
- Japan
- Prior art keywords
- demethoxygeldanamycin
- aminoethyl
- micelles
- loaded
- days
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 239000000693 micelle Substances 0.000 description 5
- JRZJKWGQFNTSRN-UHFFFAOYSA-N Geldanamycin Natural products C1C(C)CC(OC)C(O)C(C)C=C(C)C(OC(N)=O)C(OC)CCC=C(C)C(=O)NC2=CC(=O)C(OC)=C1C2=O JRZJKWGQFNTSRN-UHFFFAOYSA-N 0.000 description 2
- 229940079593 drug Drugs 0.000 description 2
- 239000003814 drug Substances 0.000 description 2
- QTQAWLPCGQOSGP-GBTDJJJQSA-N geldanamycin Chemical compound N1C(=O)\C(C)=C/C=C\[C@@H](OC)[C@H](OC(N)=O)\C(C)=C/[C@@H](C)[C@@H](O)[C@H](OC)C[C@@H](C)CC2=C(OC)C(=O)C=C1C2=O QTQAWLPCGQOSGP-GBTDJJJQSA-N 0.000 description 2
- 229940002612 prodrug Drugs 0.000 description 2
- 239000000651 prodrug Substances 0.000 description 2
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US67046005P | 2005-04-12 | 2005-04-12 | |
| US71600005P | 2005-09-09 | 2005-09-09 | |
| PCT/US2006/013800 WO2006110862A2 (en) | 2005-04-12 | 2006-04-12 | Micelle composition of polymer and passenger drug |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2008535927A JP2008535927A (ja) | 2008-09-04 |
| JP2008535927A5 true JP2008535927A5 (https=) | 2008-12-25 |
Family
ID=37011968
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2008506677A Pending JP2008535927A (ja) | 2005-04-12 | 2006-04-12 | ポリマー及びパッセンジャー薬のミセル組成物 |
Country Status (7)
| Country | Link |
|---|---|
| US (2) | US8173167B2 (https=) |
| EP (1) | EP1871343A2 (https=) |
| JP (1) | JP2008535927A (https=) |
| KR (1) | KR20080009196A (https=) |
| AU (1) | AU2006235538A1 (https=) |
| CA (1) | CA2603987A1 (https=) |
| WO (1) | WO2006110862A2 (https=) |
Families Citing this family (51)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU2003230761A1 (en) * | 2002-03-29 | 2003-10-13 | Abbott Laboratories | Polymeric micelle formulations of hydrophobic compounds and methods |
| US20080082036A1 (en) * | 2006-04-25 | 2008-04-03 | Medtronic, Inc. | Cerebrospinal fluid shunt having long term anti-occlusion agent delivery |
| US20100119529A1 (en) * | 2006-05-12 | 2010-05-13 | Furgeson Darin Y | Elastin-like polymer delivery vehicles |
| DE102006038233A1 (de) * | 2006-08-07 | 2008-02-14 | Biotronik Vi Patent Ag | Markerkomposit für medizinische Implantate |
| US20080102127A1 (en) * | 2006-10-26 | 2008-05-01 | Gao Hai Y | Hybrid lipid-polymer nanoparticulate delivery composition |
| EP2131814A4 (en) * | 2007-02-26 | 2011-08-03 | Wisconsin Alumni Res Found | POLYMIC MICROMS FOR THE RELEASE OF ACTIVE COMPOUNDS |
| WO2009006311A2 (en) * | 2007-06-29 | 2009-01-08 | Wisconsin Alumni Research Foundation | Structuring effect of cholesterol in peg-phospholipid micelles, drug delivery of amphotericin b, and combination antifungals |
| WO2009009067A2 (en) * | 2007-07-09 | 2009-01-15 | Kwon Glen S | Micelle encapsulation of theropeutic agents |
| US9422234B2 (en) * | 2007-11-30 | 2016-08-23 | The Johns Hopkins University | Prostate specific membrane antigen (PSMA) targeted nanoparticles for therapy of prostate cancer |
| US20090209757A1 (en) * | 2008-01-10 | 2009-08-20 | Santiago Ini | Processes for the preparation and purification of paliperidone palmitate |
| US20090232762A1 (en) * | 2008-03-11 | 2009-09-17 | May Pang Xiong | Compositions for delivery of therapeutic agents |
| US9271929B2 (en) * | 2008-11-25 | 2016-03-01 | École Polytechnique Fédérale De Lausanne (Epfl) | Block copolymers and uses thereof |
| WO2010120599A2 (en) * | 2009-04-16 | 2010-10-21 | Merck Sharp & Dohme Corp. | Compositions and methods for treating cancer |
| US20120082717A1 (en) * | 2009-06-05 | 2012-04-05 | Snu R&Db Foundation | Complex, multilayer using the same, and device coated with the multilayer |
| EP2480207B1 (en) | 2009-09-25 | 2016-11-09 | Wisconsin Alumni Research Foundation | Micelle encapsulation of therapeutic agents |
| US9283211B1 (en) | 2009-11-11 | 2016-03-15 | Rapamycin Holdings, Llc | Oral rapamycin preparation and use for stomatitis |
| WO2015161139A1 (en) | 2014-04-16 | 2015-10-22 | Rapamycin Holdings, Llc | Oral rapamycin preparation and use for stomatitis |
| AU2016202636B2 (en) * | 2009-12-30 | 2017-06-08 | Caliber Therapeutics, Llc | Balloon catheter systems for delivery of dry drug delivery vesicles to a vessel in the body |
| ES2845398T3 (es) | 2009-12-30 | 2021-07-26 | Caliber Therapeutics Llc | Sistemas de catéter de balón para administración de vesículas de administración de fármacos secos a un vaso en el cuerpo |
| KR101267813B1 (ko) | 2009-12-30 | 2013-06-04 | 주식회사 삼양바이오팜 | 향상된 수용해도를 갖는 라파마이신 함유 고분자나노입자 주사제형 조성물 및 그 제조방법, 및 방사선 요법과 병용하기 위한 항암 조성물 |
| EP2382966A1 (en) * | 2010-03-12 | 2011-11-02 | DSM IP Assets B.V. | Micelle compositions and process for the preparation thereof |
| MX374963B (es) | 2011-04-29 | 2025-03-06 | Selecta Biosciences Inc | Nanoportadores sintéticos tolerogénicos para reducir las respuestas de anticuerpos. |
| US8945627B2 (en) * | 2011-05-05 | 2015-02-03 | Wisconsin Alumni Research Foundation | Micelles for the solubilization of gossypol |
| CN102293736B (zh) * | 2011-08-31 | 2013-06-05 | 兰州大学 | 紫杉醇-聚合物载药胶束制备工艺 |
| JP2013203680A (ja) * | 2012-03-28 | 2013-10-07 | Kobe Gakuin | ビタミンe誘導体を含有する血中滞留性薬物キャリアー粒子 |
| CN103845290A (zh) | 2012-12-03 | 2014-06-11 | 曼丽国际有限公司 | Umirolimus及其衍生物用于治疗癌症的用途 |
| WO2014093631A1 (en) * | 2012-12-12 | 2014-06-19 | University Of Pittsburgh - Of The Commonwealth System Of Higher Education | Formulations and carrier systems including compound interactive domains |
| CN103142479A (zh) * | 2013-03-29 | 2013-06-12 | 中国药科大学 | 一种磷脂-维生素e琥珀酸聚乙二醇酯胶束的应用 |
| BR122020023215B1 (pt) | 2013-05-03 | 2022-11-22 | Selecta Biosciences, Inc | Composição e kit de nanocarreadores sintéticos tolerogênicos para reduzir ou prevenir anafilaxia em resposta a um antígeno não alergênico |
| US10682415B2 (en) | 2013-07-22 | 2020-06-16 | Wisconsin Alumni Research Foundation | Thermogel formulation for combination drug delivery |
| WO2015013510A1 (en) | 2013-07-25 | 2015-01-29 | Ecole Polytechnique Federale De Lausanne Epfl | High aspect ratio nanofibril materials |
| EP3089737B1 (en) * | 2013-12-31 | 2021-11-03 | Rapamycin Holdings, LLC | Oral rapamycin nanoparticle preparations and use |
| US9700544B2 (en) * | 2013-12-31 | 2017-07-11 | Neal K Vail | Oral rapamycin nanoparticle preparations |
| HUP1400075A2 (hu) | 2014-02-14 | 2015-08-28 | Druggability Technologies Ip Holdco Jersey Ltd | Sirolimus és származékainak komplexei, elõállítása és gyógyszerészeti kompozíciói |
| US9855341B2 (en) | 2014-02-19 | 2018-01-02 | University of Pittsburgh—of the Commonwealth System of Higher Education | Formulations and carrier systems including farnesylthiosalycylic moities |
| CA2954064C (en) | 2014-07-02 | 2018-10-30 | The Research Foundation For The State University Of New York | Surfactant-stripped micelle compositions with high cargo to surfactant ratio |
| JP7242180B2 (ja) | 2014-09-07 | 2023-03-20 | セレクタ バイオサイエンシーズ インコーポレーテッド | 抗ウイルス導入ベクター免疫応答を減弱化するための方法および組成物 |
| US11633355B2 (en) | 2014-12-12 | 2023-04-25 | Clemson University Research Foundation | Multi-functional particles and methods of using the same |
| US10232050B1 (en) | 2014-12-12 | 2019-03-19 | Clemson University | Multi-functional particles and methods of using the same |
| BR112018000217A2 (pt) * | 2015-07-15 | 2018-09-04 | Celator Pharmaceuticals Inc | sistemas de distribuição de nanopartículas aperfeiçoados |
| CN105232459B (zh) * | 2015-09-24 | 2018-10-16 | 沈阳药科大学 | 一种复溶自组装的水难溶性药物聚合物胶束组合物及其制备方法 |
| ES3036482T3 (en) | 2017-03-11 | 2025-09-19 | Cartesian Therapeutics Inc | Methods and compositions related to combined treatment with anti-inflammatories and synthetic nanocarriers comprising an immunosuppressant |
| US20190029970A1 (en) * | 2017-07-31 | 2019-01-31 | The Chinese University Of Hong Kong | Fatty acid conjugated nanoparticles and uses thereof |
| US11857634B2 (en) | 2018-04-20 | 2024-01-02 | University of Pittsburgh—of the Commonwealth System of Higher Education | Cationic amphiphilic polymers for codelivery of hydrophobic agents and nucleic acids |
| WO2020077170A1 (en) | 2018-10-12 | 2020-04-16 | University Of Pittsburgh- Of The Commonwealth System Of Higher Education | Small polymeric carriers for delivery of agents |
| KR102051593B1 (ko) | 2018-11-15 | 2020-01-08 | 재단법인대구경북과학기술원 | 이중 반응형 양친매성 화합물, 이의 제조방법 및 이를 이용한 약물 전달체 |
| AU2020287627A1 (en) | 2019-06-04 | 2021-11-18 | Selecta Biosciences, Inc. | Formulations and doses of PEGylated uricase |
| CN111358754A (zh) * | 2020-03-13 | 2020-07-03 | 广州白云山汉方现代药业有限公司 | 一种大环内酯类抗生素长循环乳剂及其制备方法 |
| IT202000007228A1 (it) * | 2020-04-06 | 2021-10-06 | Diego Dolcetta | SOMMINISTRAZIONE DI INIBITORI DI mTOR NEL SISTEMA NERVOSO CENTRALE |
| KR102701406B1 (ko) * | 2021-10-18 | 2024-08-30 | 재단법인대구경북과학기술원 | 토코페롤을 포함하는 활성 산소 반응형 믹토암 양친매성 화합물, 이의 제조 방법, 및 이를 이용한 약물 전달체 |
| WO2025095862A1 (en) * | 2023-10-30 | 2025-05-08 | National University Of Singapore | A composition, a method of making the composition and its uses thereof |
Family Cites Families (22)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6090414A (en) * | 1970-05-20 | 2000-07-18 | Life Science Labs, Inc. | Method and composition to reduce cancer incidence |
| US4261989A (en) | 1979-02-19 | 1981-04-14 | Kaken Chemical Co. Ltd. | Geldanamycin derivatives and antitumor drug |
| US5536729A (en) * | 1993-09-30 | 1996-07-16 | American Home Products Corporation | Rapamycin formulations for oral administration |
| US5580899A (en) | 1995-01-09 | 1996-12-03 | The Liposome Company, Inc. | Hydrophobic taxane derivatives |
| US6107332A (en) * | 1995-09-12 | 2000-08-22 | The Liposome Company, Inc. | Hydrolysis-promoting hydrophobic taxane derivatives |
| ATE309235T1 (de) * | 1995-09-12 | 2005-11-15 | Zeneus Pharma Ltd | Hydrolyse-einleitende hydrophobe taxane derivate |
| US6284267B1 (en) * | 1996-08-14 | 2001-09-04 | Nutrimed Biotech | Amphiphilic materials and liposome formulations thereof |
| US6458373B1 (en) * | 1997-01-07 | 2002-10-01 | Sonus Pharmaceuticals, Inc. | Emulsion vehicle for poorly soluble drugs |
| US6322810B1 (en) | 1997-07-14 | 2001-11-27 | Hayat Alkan-Onyuksel | Materials and methods for making improved micelle compositions |
| US6217886B1 (en) * | 1997-07-14 | 2001-04-17 | The Board Of Trustees Of The University Of Illinois | Materials and methods for making improved micelle compositions |
| AU1678900A (en) * | 1998-08-11 | 2000-03-06 | All India Institute Of Medical Sciences | A novel liposomal formulation useful in treatment of cancer and other proliferation diseases |
| US6469132B1 (en) | 1999-05-05 | 2002-10-22 | Mcgill University | Diblock copolymer and use thereof in a micellar drug delivery system |
| CA2408548C (en) * | 2000-05-12 | 2008-03-11 | Samyang Corporation | Method for the preparation of polymeric micelle via phase separation of block copolymer |
| US6764507B2 (en) * | 2000-10-16 | 2004-07-20 | Conor Medsystems, Inc. | Expandable medical device with improved spatial distribution |
| US8067032B2 (en) * | 2000-12-22 | 2011-11-29 | Baxter International Inc. | Method for preparing submicron particles of antineoplastic agents |
| TWI246524B (en) * | 2001-01-19 | 2006-01-01 | Shearwater Corp | Multi-arm block copolymers as drug delivery vehicles |
| WO2003002096A1 (en) | 2001-06-28 | 2003-01-09 | Wisconsin Alumni Research Foundation | Methods and compositions for polyene antibiotics with reduced toxicity |
| US6872715B2 (en) | 2001-08-06 | 2005-03-29 | Kosan Biosciences, Inc. | Benzoquinone ansamycins |
| AU2003253645A1 (en) | 2002-06-12 | 2003-12-31 | The Board Of Trustees Of The University Of Illinois | Phospholipid micelles in liposomes as solubilizers for water-insoluble compounds |
| US20040116360A1 (en) | 2002-10-15 | 2004-06-17 | Kwon Glen S. | Encapsulation and deaggregation of polyene antibiotics using poly(ethylene glycol)-phospholipid micelles |
| US20050026893A1 (en) | 2003-05-30 | 2005-02-03 | Kosan Biosciences, Inc. | Method for treating diseases using HSP90-inhibiting agents in combination with immunosuppressants |
| AU2005269800B8 (en) | 2004-07-19 | 2011-12-01 | Jazz Pharmaceuticals Therapeutics, Inc. | Particulate constructs for release of active agents |
-
2006
- 2006-04-12 AU AU2006235538A patent/AU2006235538A1/en not_active Abandoned
- 2006-04-12 WO PCT/US2006/013800 patent/WO2006110862A2/en not_active Ceased
- 2006-04-12 CA CA002603987A patent/CA2603987A1/en not_active Abandoned
- 2006-04-12 US US11/402,639 patent/US8173167B2/en not_active Expired - Fee Related
- 2006-04-12 KR KR1020077025059A patent/KR20080009196A/ko not_active Withdrawn
- 2006-04-12 JP JP2008506677A patent/JP2008535927A/ja active Pending
- 2006-04-12 EP EP06758321A patent/EP1871343A2/en not_active Withdrawn
-
2012
- 2012-04-30 US US13/460,366 patent/US9107814B2/en not_active Expired - Fee Related
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