JP2008533988A - セネカバレーウイルスを基盤とする組成物及び疾患を治療する方法 - Google Patents

セネカバレーウイルスを基盤とする組成物及び疾患を治療する方法 Download PDF

Info

Publication number
JP2008533988A
JP2008533988A JP2008503027A JP2008503027A JP2008533988A JP 2008533988 A JP2008533988 A JP 2008533988A JP 2008503027 A JP2008503027 A JP 2008503027A JP 2008503027 A JP2008503027 A JP 2008503027A JP 2008533988 A JP2008533988 A JP 2008533988A
Authority
JP
Japan
Prior art keywords
svv
virus
seq
sequence
cells
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2008503027A
Other languages
English (en)
Japanese (ja)
Other versions
JP2008533988A5 (enExample
Inventor
ポール ハレンベック
セシダー レディー ポリス
ローラ エム ヘイルズ
Original Assignee
ネオトロピックス インコーポレイテッド
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by ネオトロピックス インコーポレイテッド filed Critical ネオトロピックス インコーポレイテッド
Publication of JP2008533988A publication Critical patent/JP2008533988A/ja
Publication of JP2008533988A5 publication Critical patent/JP2008533988A5/ja
Pending legal-status Critical Current

Links

Images

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/66—Microorganisms or materials therefrom
    • A61K35/76—Viruses; Subviral particles; Bacteriophages
    • A61K35/768—Oncolytic viruses not provided for in groups A61K35/761 - A61K35/766
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/08—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from viruses
    • C07K16/10—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from viruses from RNA viruses
    • C07K16/1009—Picornaviridae, e.g. hepatitis A virus
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N7/00—Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
    • G01N33/5008—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
    • G01N33/5011—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics for testing antineoplastic activity
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/525—Virus
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2770/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
    • C12N2770/00011—Details
    • C12N2770/32011—Picornaviridae
    • C12N2770/32021—Viruses as such, e.g. new isolates, mutants or their genomic sequences
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2770/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
    • C12N2770/00011—Details
    • C12N2770/32011—Picornaviridae
    • C12N2770/32022—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2770/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
    • C12N2770/00011—Details
    • C12N2770/32011—Picornaviridae
    • C12N2770/32032—Use of virus as therapeutic agent, other than vaccine, e.g. as cytolytic agent
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2770/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
    • C12N2770/00011—Details
    • C12N2770/32011—Picornaviridae
    • C12N2770/32033—Use of viral protein as therapeutic agent other than vaccine, e.g. apoptosis inducing or anti-inflammatory
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2770/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
    • C12N2770/00011—Details
    • C12N2770/32011—Picornaviridae
    • C12N2770/32061—Methods of inactivation or attenuation
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/005—Assays involving biological materials from specific organisms or of a specific nature from viruses
    • G01N2333/08—RNA viruses
    • G01N2333/085—Picornaviridae, e.g. coxsackie virus, echovirus, enterovirus

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Virology (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Microbiology (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • Biotechnology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • General Engineering & Computer Science (AREA)
  • Oncology (AREA)
  • Mycology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Epidemiology (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • General Physics & Mathematics (AREA)
  • Communicable Diseases (AREA)
  • Cell Biology (AREA)
  • Pathology (AREA)
  • Toxicology (AREA)
  • Food Science & Technology (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
JP2008503027A 2005-03-23 2006-03-13 セネカバレーウイルスを基盤とする組成物及び疾患を治療する方法 Pending JP2008533988A (ja)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US66444205P 2005-03-23 2005-03-23
US72631305P 2005-10-13 2005-10-13
US11/335,891 US7638318B2 (en) 2003-09-26 2006-01-19 Seneca Valley virus based compositions and methods for treating disease
PCT/US2006/009142 WO2006101841A2 (en) 2005-03-23 2006-03-13 Seneca valley virus based compositions and methods for treating disease

Publications (2)

Publication Number Publication Date
JP2008533988A true JP2008533988A (ja) 2008-08-28
JP2008533988A5 JP2008533988A5 (enExample) 2009-04-30

Family

ID=37024337

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2008503027A Pending JP2008533988A (ja) 2005-03-23 2006-03-13 セネカバレーウイルスを基盤とする組成物及び疾患を治療する方法

Country Status (5)

Country Link
US (4) US7638318B2 (enExample)
EP (1) EP1868654A4 (enExample)
JP (1) JP2008533988A (enExample)
CA (1) CA2602676A1 (enExample)
WO (1) WO2006101841A2 (enExample)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20200027479A (ko) * 2017-07-12 2020-03-12 베링거 인겔하임 애니멀 헬스 유에스에이 인크. 세네카바이러스 a 면역원성 조성물 및 이의 방법

Families Citing this family (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7638318B2 (en) 2003-09-26 2009-12-29 Norvartis Ag Seneca Valley virus based compositions and methods for treating disease
AU2012216555B2 (en) * 2006-06-13 2013-10-17 Helix Biomedix Inc. Peptide fragments for inducing synthesis of extracellular matrix proteins
EP3002294B8 (en) 2006-06-13 2018-05-16 Helix Biomedix Inc. Peptide fragments for inducing synthesis of extracellular matrix proteins
WO2008112891A2 (en) * 2007-03-13 2008-09-18 Neotropix, Inc. Monoclonal antibody that recognizes a seneca valley virus (svv) cellular receptor and uses thereof
US8980545B2 (en) 2008-03-20 2015-03-17 Blood Systems, Inc. Divergent picornavirus: cosavirus
WO2011041788A2 (en) * 2009-10-02 2011-04-07 The Trustees Of Columbia University In The City Of New York Turkey viral hepatitis virus and uses thereof
CA3045771A1 (en) 2015-12-02 2017-06-08 Memorial Sloan-Kettering Cancer Center Seneca valley virus (svv) cellular receptor targeted oncotherapy
WO2017181070A1 (en) * 2016-04-15 2017-10-19 Kansas State University Research Foundation Vaccine against seneca valley virus
CN107034313A (zh) * 2017-05-10 2017-08-11 广东温氏食品集团股份有限公司 一对塞尼卡谷病毒的rt‑pcr检测引物及rt‑pcr检测方法
CN107513524B (zh) * 2017-09-30 2021-02-09 中牧实业股份有限公司 一株猪塞内加谷病毒毒株及其应用
CN107937617A (zh) * 2017-12-28 2018-04-20 广州维佰生物科技有限公司 检测塞内加谷病毒的rt‑lamp引物组合物及其试剂盒和方法
CN108300811A (zh) * 2018-04-18 2018-07-20 滕建芬 一种猪塞尼卡谷病毒的rt-pcr检测试剂盒及其检测方法
CN110551694B (zh) * 2018-06-01 2021-03-19 金宇保灵生物药品有限公司 塞尼卡谷病毒svv/ch/zz/2016
SG11202107282VA (en) * 2019-01-04 2021-07-29 Oncorus Inc Encapsulated rna polynucleotides and methods of use
CN109679927B (zh) * 2019-02-25 2021-04-09 中国农业科学院兰州兽医研究所 猪塞内加谷病毒、猪塞内加谷病毒灭活疫苗的制备方法、猪塞内加谷病毒灭活疫苗和应用
CN111733144A (zh) * 2019-03-25 2020-10-02 金宇保灵生物药品有限公司 一种塞内卡病毒的纯化方法及病毒液的浓缩纯化方法
BR112022000928A2 (pt) 2019-07-19 2022-03-08 Seneca Therapeutics Inc Terapia oncolítica do vírus seneca valley de segunda geração: composições e métodos da mesma
CN111202029A (zh) * 2020-02-26 2020-05-29 金宇保灵生物药品有限公司 一种塞内卡病毒家兔动物模型的建立方法及其应用
CN116782941A (zh) * 2021-01-11 2023-09-19 塞内卡治疗公司 用于治疗检查点抑制剂难治性癌症的塞尼卡谷病毒组合治疗
CA3207261A1 (en) * 2021-01-19 2022-07-28 Seneca Therapeutics, Inc. Armed seneca valley virus oncolytic therapy compositions and methods thereof
CN113504369B (zh) * 2021-06-23 2024-07-05 阳普医疗科技股份有限公司 一种消除标本溶血所致血清神经特异性烯醇化酶检测阳性干扰的个体化纠正公式及其应用
CN114164179A (zh) * 2021-11-29 2022-03-11 河南省动物疫病预防控制中心 分泌抗sva抗体的杂交瘤细胞及其分泌的抗体与应用
WO2023223183A1 (en) * 2022-05-16 2023-11-23 Crispr Therapeutics Ag Picornaviral vectors for gene editing
CN117281824B (zh) * 2023-08-11 2025-10-21 华南农业大学 Trim基因的过表达剂在制备抑制猪塞内卡病毒复制的产品中的应用
CN118812726B (zh) * 2024-06-26 2025-05-16 西北民族大学 脑心肌炎多抗原表位重组蛋白及其在制备脑心肌炎疫苗中的应用

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5708157A (en) * 1996-07-26 1998-01-13 Genetics Institute, Inc. Secreted proteins and polynucleotides encoding them

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5270192A (en) * 1991-02-07 1993-12-14 Monsanto Company Biological artificial liver
AUPN720195A0 (en) 1995-12-18 1996-01-18 University Of Melbourne, The Equine rhinovirus 1 proteins
US6110461A (en) 1997-08-13 2000-08-29 Oncolytics Biotech Inc. Reovirus for the treatment of neoplasia
US6821519B2 (en) 2000-06-29 2004-11-23 Corixa Corporation Compositions and methods for the diagnosis and treatment of herpes simplex virus infection
SE0102198D0 (sv) 2001-06-20 2001-06-20 Gun Frisk New sequences
US7638318B2 (en) * 2003-09-26 2009-12-29 Norvartis Ag Seneca Valley virus based compositions and methods for treating disease
EP1668025B1 (en) 2003-09-26 2014-06-25 Novartis AG Seneca valley virus based compositions and methods for treating disease

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5708157A (en) * 1996-07-26 1998-01-13 Genetics Institute, Inc. Secreted proteins and polynucleotides encoding them

Cited By (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20200027479A (ko) * 2017-07-12 2020-03-12 베링거 인겔하임 애니멀 헬스 유에스에이 인크. 세네카바이러스 a 면역원성 조성물 및 이의 방법
JP2020529195A (ja) * 2017-07-12 2020-10-08 ベーリンガー インゲルハイム アニマル ヘルス ユーエスエイ インコーポレイテッド セネカウイルスａ免疫原性組成物およびその方法
JP7083362B2 (ja) 2017-07-12 2022-06-10 ベーリンガー インゲルハイム アニマル ヘルス ユーエスエイ インコーポレイテッド セネカウイルスａ免疫原性組成物およびその方法
JP2022125026A (ja) * 2017-07-12 2022-08-26 ベーリンガー インゲルハイム アニマル ヘルス ユーエスエイ インコーポレイテッド セネカウイルスａ免疫原性組成物およびその方法
JP7413440B2 (ja) 2017-07-12 2024-01-15 ベーリンガー インゲルハイム アニマル ヘルス ユーエスエイ インコーポレイテッド セネカウイルスａ免疫原性組成物およびその方法
KR102768038B1 (ko) * 2017-07-12 2025-02-18 베링거 인겔하임 애니멀 헬스 유에스에이 인크. 세네카바이러스 a 면역원성 조성물 및 이의 방법

Also Published As

Publication number Publication date
US7638318B2 (en) 2009-12-29
US20140348798A1 (en) 2014-11-27
WO2006101841A3 (en) 2008-01-24
EP1868654A4 (en) 2009-07-08
WO2006101841A2 (en) 2006-09-28
US20100129325A1 (en) 2010-05-27
US8039606B2 (en) 2011-10-18
CA2602676A1 (en) 2006-09-28
US20120034676A1 (en) 2012-02-09
US20060159659A1 (en) 2006-07-20
US8753622B2 (en) 2014-06-17
EP1868654A2 (en) 2007-12-26

Similar Documents

Publication Publication Date Title
US8039606B2 (en) Seneca Valley virus based compositions and methods for treating disease
CN1875028B (zh) 基于 Seneca Valley 病毒的组合物以及疾病的治疗方法
Ontiveros et al. Enhanced virulence mediated by the murine coronavirus, mouse hepatitis virus strain JHM, is associated with a glycine at residue 310 of the spike glycoprotein
US20120328575A1 (en) Modified Oncolytic Viruses
DeJesus et al. Mutation of a single conserved nucleotide between the cloverleaf and internal ribosome entry site attenuates poliovirus neurovirulence
Paananen et al. Molecular and biological analysis of echovirus 9 strain isolated from a diabetic child
CN101448526A (zh) 基于西尼加谷病毒的组合物和治疗疾病的方法
Gibson et al. Expression and processing of nonstructural proteins of the human astroviruses
Israelsson et al. Studies of Echovirus 5 interactions with the cell surface: heparan sulfate mediates attachment to the host cell
Ramsingh et al. Evidence suggesting that virulence maps to the P1 region of the coxsackievirus B4 genome
HK1094583B (en) Seneca valley virus based compositions and methods for treating disease
Jia et al. Isolation and molecular characterization of a poliovirus type 1 mutant that replicates in the spinal cords of mice
Chatterjee et al. Isolation and characterization of a membrane-bound population of group B coxsackieviruses
Poirier Preclinical and clinical studies of Seneca Valley Virus, a therapeutically promising oncolytic picornavirus with neuroendocrine tropism
Johnston et al. Theiler’s murine encephalomyelitis virus 3D RNA polymerase: Its expression in the CNS and the specific immune response generated in persistently infected mice
Rames The etiopathogenesis of Theiler's murine encephalomyelitis virus (TMEV)-induced cardiomyopathy, including characterization of new strains of TMEV
McCarthy Thermal Selection of Seneca Valley Virus Gives Rise to a Novel Thermostable Mutant
Wollenberg Tweaking reovirus T3D to boost the oncolytic potency

Legal Events

Date Code Title Description
A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A523

Effective date: 20090313

A621 Written request for application examination

Free format text: JAPANESE INTERMEDIATE CODE: A621

Effective date: 20090313

A131 Notification of reasons for refusal

Free format text: JAPANESE INTERMEDIATE CODE: A131

Effective date: 20111205

A02 Decision of refusal

Free format text: JAPANESE INTERMEDIATE CODE: A02

Effective date: 20120521