CA2602676A1 - Seneca valley virus based compositions and methods for treating disease - Google Patents

Seneca valley virus based compositions and methods for treating disease Download PDF

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Publication number
CA2602676A1
CA2602676A1 CA002602676A CA2602676A CA2602676A1 CA 2602676 A1 CA2602676 A1 CA 2602676A1 CA 002602676 A CA002602676 A CA 002602676A CA 2602676 A CA2602676 A CA 2602676A CA 2602676 A1 CA2602676 A1 CA 2602676A1
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CA
Canada
Prior art keywords
svv
virus
seq
sequence
cell
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Abandoned
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CA002602676A
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English (en)
French (fr)
Inventor
Paul Hallenbeck
Seshidhar Reddy Police
Laura M. Hales
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NEOTROPIX Inc
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NEOTROPIX Inc
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Publication of CA2602676A1 publication Critical patent/CA2602676A1/en
Abandoned legal-status Critical Current

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/66—Microorganisms or materials therefrom
    • A61K35/76—Viruses; Subviral particles; Bacteriophages
    • A61K35/768—Oncolytic viruses not provided for in groups A61K35/761 - A61K35/766
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/08—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from viruses
    • C07K16/10—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from viruses from RNA viruses
    • C07K16/1009—Picornaviridae, e.g. hepatitis A virus
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N7/00—Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
    • G01N33/5008—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
    • G01N33/5011—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics for testing antineoplastic activity
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/525—Virus
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2770/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
    • C12N2770/00011—Details
    • C12N2770/32011—Picornaviridae
    • C12N2770/32021—Viruses as such, e.g. new isolates, mutants or their genomic sequences
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2770/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
    • C12N2770/00011—Details
    • C12N2770/32011—Picornaviridae
    • C12N2770/32022—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2770/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
    • C12N2770/00011—Details
    • C12N2770/32011—Picornaviridae
    • C12N2770/32032—Use of virus as therapeutic agent, other than vaccine, e.g. as cytolytic agent
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2770/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
    • C12N2770/00011—Details
    • C12N2770/32011—Picornaviridae
    • C12N2770/32033—Use of viral protein as therapeutic agent other than vaccine, e.g. apoptosis inducing or anti-inflammatory
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2770/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
    • C12N2770/00011—Details
    • C12N2770/32011—Picornaviridae
    • C12N2770/32061—Methods of inactivation or attenuation
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/005—Assays involving biological materials from specific organisms or of a specific nature from viruses
    • G01N2333/08—RNA viruses
    • G01N2333/085—Picornaviridae, e.g. coxsackie virus, echovirus, enterovirus

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Virology (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Microbiology (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • Biotechnology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • General Engineering & Computer Science (AREA)
  • Oncology (AREA)
  • Mycology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Epidemiology (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • General Physics & Mathematics (AREA)
  • Communicable Diseases (AREA)
  • Cell Biology (AREA)
  • Pathology (AREA)
  • Toxicology (AREA)
  • Food Science & Technology (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
CA002602676A 2005-03-23 2006-03-13 Seneca valley virus based compositions and methods for treating disease Abandoned CA2602676A1 (en)

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
US66444205P 2005-03-23 2005-03-23
US60/664,442 2005-03-23
US72631305P 2005-10-13 2005-10-13
US60/726,313 2005-10-13
US11/335,891 US7638318B2 (en) 2003-09-26 2006-01-19 Seneca Valley virus based compositions and methods for treating disease
US11/335,891 2006-01-19
PCT/US2006/009142 WO2006101841A2 (en) 2005-03-23 2006-03-13 Seneca valley virus based compositions and methods for treating disease

Publications (1)

Publication Number Publication Date
CA2602676A1 true CA2602676A1 (en) 2006-09-28

Family

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Family Applications (1)

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CA002602676A Abandoned CA2602676A1 (en) 2005-03-23 2006-03-13 Seneca valley virus based compositions and methods for treating disease

Country Status (5)

Country Link
US (4) US7638318B2 (enExample)
EP (1) EP1868654A4 (enExample)
JP (1) JP2008533988A (enExample)
CA (1) CA2602676A1 (enExample)
WO (1) WO2006101841A2 (enExample)

Families Citing this family (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7638318B2 (en) 2003-09-26 2009-12-29 Norvartis Ag Seneca Valley virus based compositions and methods for treating disease
AU2012216555B2 (en) * 2006-06-13 2013-10-17 Helix Biomedix Inc. Peptide fragments for inducing synthesis of extracellular matrix proteins
EP3002294B8 (en) 2006-06-13 2018-05-16 Helix Biomedix Inc. Peptide fragments for inducing synthesis of extracellular matrix proteins
WO2008112891A2 (en) * 2007-03-13 2008-09-18 Neotropix, Inc. Monoclonal antibody that recognizes a seneca valley virus (svv) cellular receptor and uses thereof
US8980545B2 (en) 2008-03-20 2015-03-17 Blood Systems, Inc. Divergent picornavirus: cosavirus
WO2011041788A2 (en) * 2009-10-02 2011-04-07 The Trustees Of Columbia University In The City Of New York Turkey viral hepatitis virus and uses thereof
CA3045771A1 (en) 2015-12-02 2017-06-08 Memorial Sloan-Kettering Cancer Center Seneca valley virus (svv) cellular receptor targeted oncotherapy
WO2017181070A1 (en) * 2016-04-15 2017-10-19 Kansas State University Research Foundation Vaccine against seneca valley virus
CN107034313A (zh) * 2017-05-10 2017-08-11 广东温氏食品集团股份有限公司 一对塞尼卡谷病毒的rt‑pcr检测引物及rt‑pcr检测方法
EP3651797A1 (en) * 2017-07-12 2020-05-20 Boehringer Ingelheim Animal Health USA Inc. Senecavirus a immunogenic compositions and methods thereof
CN107513524B (zh) * 2017-09-30 2021-02-09 中牧实业股份有限公司 一株猪塞内加谷病毒毒株及其应用
CN107937617A (zh) * 2017-12-28 2018-04-20 广州维佰生物科技有限公司 检测塞内加谷病毒的rt‑lamp引物组合物及其试剂盒和方法
CN108300811A (zh) * 2018-04-18 2018-07-20 滕建芬 一种猪塞尼卡谷病毒的rt-pcr检测试剂盒及其检测方法
CN110551694B (zh) * 2018-06-01 2021-03-19 金宇保灵生物药品有限公司 塞尼卡谷病毒svv/ch/zz/2016
SG11202107282VA (en) * 2019-01-04 2021-07-29 Oncorus Inc Encapsulated rna polynucleotides and methods of use
CN109679927B (zh) * 2019-02-25 2021-04-09 中国农业科学院兰州兽医研究所 猪塞内加谷病毒、猪塞内加谷病毒灭活疫苗的制备方法、猪塞内加谷病毒灭活疫苗和应用
CN111733144A (zh) * 2019-03-25 2020-10-02 金宇保灵生物药品有限公司 一种塞内卡病毒的纯化方法及病毒液的浓缩纯化方法
BR112022000928A2 (pt) 2019-07-19 2022-03-08 Seneca Therapeutics Inc Terapia oncolítica do vírus seneca valley de segunda geração: composições e métodos da mesma
CN111202029A (zh) * 2020-02-26 2020-05-29 金宇保灵生物药品有限公司 一种塞内卡病毒家兔动物模型的建立方法及其应用
CN116782941A (zh) * 2021-01-11 2023-09-19 塞内卡治疗公司 用于治疗检查点抑制剂难治性癌症的塞尼卡谷病毒组合治疗
CA3207261A1 (en) * 2021-01-19 2022-07-28 Seneca Therapeutics, Inc. Armed seneca valley virus oncolytic therapy compositions and methods thereof
CN113504369B (zh) * 2021-06-23 2024-07-05 阳普医疗科技股份有限公司 一种消除标本溶血所致血清神经特异性烯醇化酶检测阳性干扰的个体化纠正公式及其应用
CN114164179A (zh) * 2021-11-29 2022-03-11 河南省动物疫病预防控制中心 分泌抗sva抗体的杂交瘤细胞及其分泌的抗体与应用
WO2023223183A1 (en) * 2022-05-16 2023-11-23 Crispr Therapeutics Ag Picornaviral vectors for gene editing
CN117281824B (zh) * 2023-08-11 2025-10-21 华南农业大学 Trim基因的过表达剂在制备抑制猪塞内卡病毒复制的产品中的应用
CN118812726B (zh) * 2024-06-26 2025-05-16 西北民族大学 脑心肌炎多抗原表位重组蛋白及其在制备脑心肌炎疫苗中的应用

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US7638318B2 (en) * 2003-09-26 2009-12-29 Norvartis Ag Seneca Valley virus based compositions and methods for treating disease
EP1668025B1 (en) 2003-09-26 2014-06-25 Novartis AG Seneca valley virus based compositions and methods for treating disease

Also Published As

Publication number Publication date
US7638318B2 (en) 2009-12-29
US20140348798A1 (en) 2014-11-27
WO2006101841A3 (en) 2008-01-24
EP1868654A4 (en) 2009-07-08
WO2006101841A2 (en) 2006-09-28
US20100129325A1 (en) 2010-05-27
US8039606B2 (en) 2011-10-18
US20120034676A1 (en) 2012-02-09
JP2008533988A (ja) 2008-08-28
US20060159659A1 (en) 2006-07-20
US8753622B2 (en) 2014-06-17
EP1868654A2 (en) 2007-12-26

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