JP2008531189A - ステント用金属合金 - Google Patents
ステント用金属合金 Download PDFInfo
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- JP2008531189A JP2008531189A JP2007558001A JP2007558001A JP2008531189A JP 2008531189 A JP2008531189 A JP 2008531189A JP 2007558001 A JP2007558001 A JP 2007558001A JP 2007558001 A JP2007558001 A JP 2007558001A JP 2008531189 A JP2008531189 A JP 2008531189A
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- 229910001092 metal group alloy Inorganic materials 0.000 title claims abstract description 280
- QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical compound [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 claims abstract description 54
- 229910052760 oxygen Inorganic materials 0.000 claims abstract description 54
- 239000001301 oxygen Substances 0.000 claims abstract description 54
- OKTJSMMVPCPJKN-UHFFFAOYSA-N Carbon Chemical compound [C] OKTJSMMVPCPJKN-UHFFFAOYSA-N 0.000 claims abstract description 48
- 229910052799 carbon Inorganic materials 0.000 claims abstract description 48
- 239000006104 solid solution Substances 0.000 claims abstract description 17
- 229910052702 rhenium Inorganic materials 0.000 claims description 39
- 229910052750 molybdenum Inorganic materials 0.000 claims description 36
- WUAPFZMCVAUBPE-UHFFFAOYSA-N rhenium atom Chemical compound [Re] WUAPFZMCVAUBPE-UHFFFAOYSA-N 0.000 claims description 35
- ZOKXTWBITQBERF-UHFFFAOYSA-N Molybdenum Chemical compound [Mo] ZOKXTWBITQBERF-UHFFFAOYSA-N 0.000 claims description 33
- 239000011733 molybdenum Substances 0.000 claims description 33
- IJGRMHOSHXDMSA-UHFFFAOYSA-N Atomic nitrogen Chemical compound N#N IJGRMHOSHXDMSA-UHFFFAOYSA-N 0.000 claims description 32
- 239000002245 particle Substances 0.000 claims description 18
- 229910052757 nitrogen Inorganic materials 0.000 claims description 16
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- 208000027418 Wounds and injury Diseases 0.000 description 2
- QCWXUUIWCKQGHC-UHFFFAOYSA-N Zirconium Chemical compound [Zr] QCWXUUIWCKQGHC-UHFFFAOYSA-N 0.000 description 2
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- WAIPAZQMEIHHTJ-UHFFFAOYSA-N [Cr].[Co] Chemical class [Cr].[Co] WAIPAZQMEIHHTJ-UHFFFAOYSA-N 0.000 description 1
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- 229910017052 cobalt Inorganic materials 0.000 description 1
- 238000004891 communication Methods 0.000 description 1
- 229910052802 copper Inorganic materials 0.000 description 1
- 239000010949 copper Substances 0.000 description 1
- 230000007547 defect Effects 0.000 description 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 1
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- PCHJSUWPFVWCPO-UHFFFAOYSA-N gold Chemical compound [Au] PCHJSUWPFVWCPO-UHFFFAOYSA-N 0.000 description 1
- 229910052737 gold Inorganic materials 0.000 description 1
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- 208000010125 myocardial infarction Diseases 0.000 description 1
- 210000003928 nasal cavity Anatomy 0.000 description 1
- 229910052759 nickel Inorganic materials 0.000 description 1
- 229910052758 niobium Inorganic materials 0.000 description 1
- GUCVJGMIXFAOAE-UHFFFAOYSA-N niobium atom Chemical compound [Nb] GUCVJGMIXFAOAE-UHFFFAOYSA-N 0.000 description 1
- 230000000399 orthopedic effect Effects 0.000 description 1
- 210000003101 oviduct Anatomy 0.000 description 1
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- 229910052709 silver Inorganic materials 0.000 description 1
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- 229910052715 tantalum Inorganic materials 0.000 description 1
- GUVRBAGPIYLISA-UHFFFAOYSA-N tantalum atom Chemical compound [Ta] GUVRBAGPIYLISA-UHFFFAOYSA-N 0.000 description 1
- 206010043554 thrombocytopenia Diseases 0.000 description 1
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- 210000003437 trachea Anatomy 0.000 description 1
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- WFKWXMTUELFFGS-UHFFFAOYSA-N tungsten Chemical compound [W] WFKWXMTUELFFGS-UHFFFAOYSA-N 0.000 description 1
- 229910052721 tungsten Inorganic materials 0.000 description 1
- 239000010937 tungsten Substances 0.000 description 1
- 210000002700 urine Anatomy 0.000 description 1
- 210000004291 uterus Anatomy 0.000 description 1
- 210000003462 vein Anatomy 0.000 description 1
- 229910052727 yttrium Inorganic materials 0.000 description 1
- VWQVUPCCIRVNHF-UHFFFAOYSA-N yttrium atom Chemical compound [Y] VWQVUPCCIRVNHF-UHFFFAOYSA-N 0.000 description 1
- 229910052725 zinc Inorganic materials 0.000 description 1
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
- A61L31/02—Inorganic materials
- A61L31/022—Metals or alloys
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
- A61L31/12—Composite materials, i.e. containing one material dispersed in a matrix of the same or different material
- A61L31/121—Composite materials, i.e. containing one material dispersed in a matrix of the same or different material having an inorganic matrix
- A61L31/124—Composite materials, i.e. containing one material dispersed in a matrix of the same or different material having an inorganic matrix of other specific inorganic materials not covered by A61L31/122 or A61L31/123
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
- A61L31/14—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
- A61L31/18—Materials at least partially X-ray or laser opaque
-
- C—CHEMISTRY; METALLURGY
- C22—METALLURGY; FERROUS OR NON-FERROUS ALLOYS; TREATMENT OF ALLOYS OR NON-FERROUS METALS
- C22C—ALLOYS
- C22C27/00—Alloys based on rhenium or a refractory metal not mentioned in groups C22C14/00 or C22C16/00
-
- C—CHEMISTRY; METALLURGY
- C22—METALLURGY; FERROUS OR NON-FERROUS ALLOYS; TREATMENT OF ALLOYS OR NON-FERROUS METALS
- C22C—ALLOYS
- C22C27/00—Alloys based on rhenium or a refractory metal not mentioned in groups C22C14/00 or C22C16/00
- C22C27/04—Alloys based on tungsten or molybdenum
-
- C—CHEMISTRY; METALLURGY
- C22—METALLURGY; FERROUS OR NON-FERROUS ALLOYS; TREATMENT OF ALLOYS OR NON-FERROUS METALS
- C22C—ALLOYS
- C22C30/00—Alloys containing less than 50% by weight of each constituent
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- Mechanical Engineering (AREA)
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- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Surgery (AREA)
- Veterinary Medicine (AREA)
- Heart & Thoracic Surgery (AREA)
- Organic Chemistry (AREA)
- Inorganic Chemistry (AREA)
- Metallurgy (AREA)
- Vascular Medicine (AREA)
- Optics & Photonics (AREA)
- Physics & Mathematics (AREA)
- Composite Materials (AREA)
- Materials For Medical Uses (AREA)
Abstract
【解決手段】ステントの強さおよび延性を改善する金属合金から少なくとも部分的に形成されるステントであって、該金属合金が少なくとも約99.9重量%の固溶体を含み、該金属合金が炭素および酸素を含みそして少なくとも約2.5:1の炭素対酸素の原子比を有するステント。
【選択図】図1
Description
金属/重量% 例1 例2 例3
C ≦150ppm ≦150ppm ≦150ppm
Ca 0% 0% 0%
Mg 0% 0% 0%
Mo 50−60% 50−60% 50−55%
O ≦100ppm ≦100ppm ≦100ppm
N ≦40ppm ≦40ppm ≦40ppm
Nb 0% ≦5% 0%
希土類金属 0% ≦4% 0%
Re 40−50% 40−50% 45−50%
Ta 0% ≦3% 0%
Ti 0% ≦1% 0%
W 0% ≦3% 0%
Y 0% ≦0.1% 0%
Zn 0% ≦0.1% 0%
Zr 0% ≦2% 0%
C ≦150ppm ≦150ppm ≦150ppm
Ca 0% 0% 0%
Mg 0% 0% 0%
Mo 52−55.5% 51−58% 50−56%
O ≦100ppm ≦100ppm ≦100ppm
N ≦20ppm ≦20ppm ≦20ppm
希土類金属 0% ≦0% 0%
Re 44.5−48% 2−49% 44−50%
Ta 0% 0% 0%
Ti 0% 0% 0%
W 0% 0% 0%
Y 0% 0% 0%
Zn 0% 0% 0%
Zr 0% 0% 0%
C ≦150ppm ≦50ppm ≦50ppm
Mo 51−54% 52.5−55.5% 50.5−52.4%
O ≦50ppm ≦10ppm ≦10ppm
N ≦20ppm ≦10ppm ≦10ppm
Re 46−49% 44.5−47.5% 47.6−49.5%
本発明を限定しない本発明の他のおよび/または代替の目的は、改善された成功率を有する医学用器具の提供である。
本発明を限定しない本発明の他のおよび/または代替の目的は、拡大した強さを有しそしてまたマーカー材料として使用できる新規な金属合金から少なくとも部分的に形成される医学用器具の提供である。
これらの利点および他の利点は、図面を参照しつつ本明細書の記述を読むことにより当業者に明らかになるだろう。
30 ボディ部材
32 第一の末端
34 第二の末端
36 部材構造
40 金属合金
Claims (30)
- ステントの強さおよび延性を改善する金属合金から少なくとも部分的に形成されるステントであって、該金属合金が少なくとも約99.9重量%の固溶体を含み、該金属合金が炭素および酸素を含みそして少なくとも約2.5:1の炭素対酸素の原子比を有することを特徴とするステント。
- 該金属合金が、少なくとも約99.95重量%の固溶体を含む請求項1のステント。
- 該金属合金が、少なくとも約98ksiの平均降伏強さおよび少なくとも約100ksiの平均極限引張り強さを有する請求項1または2のステント。
- 該金属合金が、少なくとも約98ksiの平均降伏強さおよび少なくとも約100ksiの平均極限引張り強さを有する請求項1、2または3のステント。
- 該金属合金が5ASTMを超える平均粒子サイズを有する請求項1−4の何れか1つの項のステント。
- 該金属合金が、少なくとも約25%の平均引張り伸びを有する請求項1−5の何れか1つの項のステント。
- 該金属合金が、約20ppmより少ない窒素含量、約150ppmより少ない炭素含量および約50ppmより少ない酸素含量を有する請求項1−6の何れか1つの項のステント。
- 該金属合金が、少なくとも13.5g/ccの平均密度を有する請求項1−7の何れか1つの項のステント。
- 該金属合金が、約46−49重量%のレニウムおよび約51−54重量%のモリブデンを含む請求項1−8の何れか1つの項のステント。
- ステントの強さおよび延性を改善する金属合金から少なくとも部分的に形成されるステントであって、該金属合金が少なくとも約95重量%の固溶体を含み、該金属合金が炭素および酸素を含みそして少なくとも約2.5:1の炭素対酸素の原子比を有し、該金属合金が少なくとも約98ksiの平均降伏強さおよび少なくとも約100ksiの平均極限引張り強さを有し、該金属合金が5ASTMを超える平均粒子サイズを有し、該金属合金が少なくとも約25%の平均引張り伸びを有することを特徴とするステント。
- 該金属合金が、少なくとも約99重量%の固溶体を含む請求項10のステント。
- 該金属合金が、炭素および酸素を含み、そして約2.5−10:1の炭素対酸素の原子比を有する請求項10または11のステント。
- 該金属合金が、約20ppmより少ない窒素含量、約150ppmより少ない炭素含量および約50ppmより少ない酸素含量を有する請求項10−12の何れか1つの項のステント。
- 該金属合金が少なくとも13.5g/ccの平均密度を有する請求項10−13の何れか1つの項のステント。
- 該金属合金が、約46−49重量%のレニウムおよび約51−54重量%のモリブデンを含む請求項10−14の何れか1つの項のステント。
- ステントの強さおよび延性を改善する金属合金から少なくとも部分的に形成されるステントであって、該金属合金が、少なくとも約95重量%のレニウムおよびモリブデンの固溶体を含み、該金属合金が、少なくとも約40重量%のレニウムおよび少なくとも約50重量%のモリブデンを含み、該合金が約2.5:1の炭素対酸素の原子比を有することを特徴とするステント。
- 該金属合金が、少なくとも約99.9重量%のレニウムおよびモリブデンを含み、該レニウム含量が、該合金の約44−48重量%である請求項16のステント。
- 該金属合金中の該炭素含量が約100ppmより少なくそして該金属合金の該酸素含量が約50ppmより少ない請求項16または17のステント。
- 該金属合金中の該炭素含量が約50ppmより少なくそして該金属合金中の該酸素含量が約10ppmより少ない請求項16−18の何れか1つの項のステント。
- 該金属合金中の炭素対酸素の該比が約2.5−10:1である請求項16−19の何れか1つの項のステント。
- 該金属合金が窒素を含み、該金属合金中の該窒素含量が約20ppmより少ない請求項16−20の何れか1つの項のステント。
- 該金属合金が、約5ASTMより大きい平均粒子サイズを有する請求項16−21の何れか1つの項のステント。
- 該金属合金が、約6−9ASTMの平均粒子サイズを有する請求項16−22の何れか1つの項のステント。
- 該金属合金が、少なくとも約25%の平均引張り伸びを有する請求項16−23の何れか1つの項のステント。
- 該金属合金が、該ステントの少なくとも約80重量%を占める請求項16−24の何れか1つの項のステント。
- 該金属合金が、重量%で、
C <150ppm
Mo 51−56%
O <50ppm
N <20ppm
Re 44−49%
を含み、そして約6−8ASTMの粒子サイズ、約2.5−10:1の炭素対酸素の比、約25−35%の平均引張り伸びを有し、そしてレニウム+モリブデンの該含量が少なくとも約99.9重量%である請求項16−25の何れか1つの項のステント。 - 該金属合金が、重量%で、
C <50ppm
Mo 52.5−55.5%
O <10ppm
N <10ppm
Re 44.5−47.5%
を含み、そして約6−7ASTMの粒子サイズ、約2.5−10:1の炭素対酸素の比、約25−35%の平均引張り伸びを有し、そしてレニウム+モリブデンの該含量が少なくとも約99.9重量%である請求項16−26の何れか1つの項のステント。 - 該金属合金が、重量%で、
C <50ppm
Mo 52.5%
O <10ppm
N <10ppm
Re 47.5%
を含み、そして約6−7ASTMの粒子サイズ、約2.5−10:1の炭素対酸素の比、約25−35%の平均引張り伸びを有し、そしてレニウム+モリブデンの該含量が少なくとも約99.9重量%である請求項16−27の何れか1つの項のステント。 - ステントの強さおよび延性を改善する少なくとも約80重量%の金属合金から形成されるステントであって、該金属合金が、少なくとも約99.9重量%のレニウムおよびモリブデンの固溶体を含み、該金属合金は炭素および酸素を含みそして約2.5−10:1の炭素対酸素の比を有し、該金属合金が少なくとも約98−122ksiの平均降伏強さおよび約100−150ksiの平均極限引張り強さを有し、該金属合金が約6−9ASTMの粒子サイズを有し、該金属合金が約25−35%の平均引張り伸びを有し、そして該金属合金が、重量%で、
C ≦150ppm
Mo 51−56%
O ≦50ppm
N ≦20ppm
Re 44−49%
を含むことを特徴とするステント。 - 該金属合金が、重量%で、
C ≦50ppm
Mo 52.5−55.5%
O ≦10ppm
N ≦10ppm
Re 44.5−47.5%
を含み、そして約6−7ASTMの粒子サイズを有する請求項29のステント。
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US65822605P | 2005-03-03 | 2005-03-03 | |
US60/658,226 | 2005-03-03 | ||
US69489105P | 2005-06-29 | 2005-06-29 | |
US69488105P | 2005-06-29 | 2005-06-29 | |
US60/694,881 | 2005-06-29 | ||
US60/694,891 | 2005-06-29 | ||
US11/282,376 | 2005-11-18 | ||
US11/282,461 | 2005-11-18 | ||
US11/282,461 US7452502B2 (en) | 2005-03-03 | 2005-11-18 | Metal alloy for a stent |
US11/282,376 US7452501B2 (en) | 2005-03-03 | 2005-11-18 | Metal alloy for a stent |
PCT/US2006/000693 WO2006096236A2 (en) | 2005-03-03 | 2006-01-09 | Metal alloy for a stent |
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JP2008538933A (ja) * | 2005-03-03 | 2008-11-13 | アイコン メディカル コーポレーション | 医療用部材用の改良された金属合金 |
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EP2104456A4 (en) * | 2007-01-16 | 2012-11-14 | Icon Medical Corp | IMPROVED METAL ALLOYS FOR MEDICAL DEVICES |
JP7184652B2 (ja) * | 2019-01-07 | 2022-12-06 | 日本特殊陶業株式会社 | 保持装置 |
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EP1893780A4 (en) | 2011-03-30 |
AU2006221100B2 (en) | 2011-01-27 |
WO2006096236A3 (en) | 2007-01-25 |
JP5335242B2 (ja) | 2013-11-06 |
EP1866453B1 (en) | 2024-05-01 |
EP1893780B1 (en) | 2024-04-24 |
AU2006221094A1 (en) | 2006-09-14 |
AU2006221100A1 (en) | 2006-09-14 |
JP2008531188A (ja) | 2008-08-14 |
AU2006221094B2 (en) | 2011-01-27 |
EP1893780A2 (en) | 2008-03-05 |
EP1866453A4 (en) | 2011-03-30 |
JP5335243B2 (ja) | 2013-11-06 |
WO2006096236A2 (en) | 2006-09-14 |
WO2006096230A2 (en) | 2006-09-14 |
WO2006096230A3 (en) | 2007-04-12 |
EP1866453A2 (en) | 2007-12-19 |
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