JP2008530171A - 新規なジアザ二環系アリール誘導体及びそれらの医療上の使用 - Google Patents
新規なジアザ二環系アリール誘導体及びそれらの医療上の使用 Download PDFInfo
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- JP2008530171A JP2008530171A JP2007555581A JP2007555581A JP2008530171A JP 2008530171 A JP2008530171 A JP 2008530171A JP 2007555581 A JP2007555581 A JP 2007555581A JP 2007555581 A JP2007555581 A JP 2007555581A JP 2008530171 A JP2008530171 A JP 2008530171A
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- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
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Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Animal Behavior & Ethology (AREA)
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- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Neurosurgery (AREA)
- Pain & Pain Management (AREA)
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- Heart & Thoracic Surgery (AREA)
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- Child & Adolescent Psychology (AREA)
- Anesthesiology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Physical Education & Sports Medicine (AREA)
- Rheumatology (AREA)
- Obesity (AREA)
- Hematology (AREA)
- Pregnancy & Childbirth (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DKPA200500229 | 2005-02-16 | ||
| US65351205P | 2005-02-17 | 2005-02-17 | |
| PCT/EP2006/050873 WO2006087305A1 (en) | 2005-02-16 | 2006-02-13 | Novel diazabicyclic aryl derivatives and their medical use |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2008530171A true JP2008530171A (ja) | 2008-08-07 |
| JP2008530171A5 JP2008530171A5 (enExample) | 2009-04-02 |
Family
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2007555581A Abandoned JP2008530171A (ja) | 2005-02-16 | 2006-02-13 | 新規なジアザ二環系アリール誘導体及びそれらの医療上の使用 |
Country Status (6)
| Country | Link |
|---|---|
| US (1) | US7750011B2 (enExample) |
| EP (1) | EP1866314B1 (enExample) |
| JP (1) | JP2008530171A (enExample) |
| AT (1) | ATE481407T1 (enExample) |
| DE (1) | DE602006016926D1 (enExample) |
| WO (1) | WO2006087305A1 (enExample) |
Families Citing this family (22)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB0220581D0 (en) | 2002-09-04 | 2002-10-09 | Novartis Ag | Organic Compound |
| PE20060437A1 (es) * | 2004-06-18 | 2006-06-08 | Novartis Ag | COMPUESTOS AZA-BICICLONONANOS COMO LIGANDOS COLINERGICOS DE nAChR |
| GB0415746D0 (en) * | 2004-07-14 | 2004-08-18 | Novartis Ag | Organic compounds |
| GB0521508D0 (en) * | 2005-10-21 | 2005-11-30 | Novartis Ag | Organic compounds |
| GB0525672D0 (en) | 2005-12-16 | 2006-01-25 | Novartis Ag | Organic compounds |
| GB0525673D0 (en) * | 2005-12-16 | 2006-01-25 | Novartis Ag | Organic compounds |
| GEP20125425B (en) * | 2006-10-18 | 2012-03-26 | Pfizer Prod Inc | Biaryl ether urea compounds |
| JP2011504909A (ja) * | 2007-11-30 | 2011-02-17 | ノイロサーチ アクティーゼルスカブ | 新規なカルボン酸４−フェニルアゾ−フェニルエステル誘導体及びモノアミン神経伝達物質再取り込み阻害薬としてのそれらの使用 |
| EP2670744B1 (en) | 2011-02-03 | 2015-05-27 | Lupin Limited | Pyrrole derivatives used as modulators of alpha7 nachr |
| AU2012221800B2 (en) | 2011-02-23 | 2016-10-27 | Lupin Limited | Heteroaryl derivatives as alpha7 nAChR modulators |
| AU2012235779B2 (en) | 2011-03-31 | 2017-03-02 | Lupin Limited | Pyrrole derivatives as nicotinic acetylcholine receptor modulators for use in the treatment of neurodegenerative disorders such as Alzheimer's and Parkinson's disease |
| ES2606043T3 (es) | 2011-07-05 | 2017-03-17 | Lupin Limited | Derivados de biarilo como moduladores de nAChR |
| WO2013132380A1 (en) | 2012-03-06 | 2013-09-12 | Lupin Limited | Thiazole derivatives as alpha 7 nachr modulators |
| WO2014072957A1 (en) | 2012-11-12 | 2014-05-15 | Lupin Limited | Thiazole derivatives as alpha 7 nachr modulators |
| US9617211B2 (en) | 2013-01-16 | 2017-04-11 | Lupin Limited | Pyrrole derivatives as alpha 7 nAChR modulators |
| US9617210B2 (en) | 2013-03-13 | 2017-04-11 | Lupin Limited | Pyrrole derivatives as alpha 7 NACHR modulators |
| TW201446243A (zh) | 2013-06-03 | 2014-12-16 | Lupin Ltd | 4-(5-(4-氯苯基)-2-(2-環丙基乙醯基)-1,4-二甲基-1氫-吡咯-3-基)苯磺醯胺作為α7尼古丁乙醯膽鹼受體調節劑 |
| WO2014203150A1 (en) | 2013-06-17 | 2014-12-24 | Lupin Limited | Pyrrole derivatives as alpha 7 nachr modulators |
| KR102218333B1 (ko) | 2016-06-07 | 2021-02-22 | 자코바이오 파마슈티칼스 컴퍼니 리미티드 | Shp2 억제제로서 유용한 신규한 헤테로환형 유도체 |
| SG11201908820VA (en) | 2017-03-23 | 2019-10-30 | Jacobio Pharmaceuticals Co Ltd | Novel heterocyclic derivatives useful as shp2 inhibitors |
| CN112839935A (zh) | 2018-09-26 | 2021-05-25 | 北京加科思新药研发有限公司 | 可用作shp2抑制剂的新型杂环衍生物 |
| CN114409669B (zh) * | 2022-01-24 | 2023-06-23 | 云南民族大学 | 一种氧杂降冰片烯环上c-5位炔基取代的斑蝥素衍生物及其制备方法与应用 |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5478939A (en) | 1994-07-20 | 1995-12-26 | American Cyanamid Company | (R,R) and (S,S) 2,5-diazabicyclo [2,2,1]heptane derivatives |
| GB9803411D0 (en) | 1998-02-18 | 1998-04-15 | Smithkline Beecham Plc | Novel compounds |
| FR2786769B1 (fr) | 1998-12-04 | 2002-10-25 | Synthelabo | Derives de 2,5-diazabicyclo[2.2.1]heptane, leur preparation et leur application en therapeutique |
| EP1147112B1 (en) | 1999-01-29 | 2003-10-29 | Abbott Laboratories | Diazabicyclic derivatives as nicotinic acetylcholine receptor ligands |
| MXPA04010966A (es) | 2002-05-07 | 2005-01-25 | Neurosearch As | Derivados novedosos de biarilo diazabiciclico. |
| DE60311853T2 (de) | 2002-09-30 | 2007-06-21 | Neurosearch A/S | Neue 1,4-diazabicycloalkanderivate, deren herstellung und verwendung |
| EP1562945B1 (en) | 2002-11-11 | 2006-11-15 | Neurosearch A/S | 1,4-diazabicyclo(3,2,2)nonane derivatives, preparation and therapeutical use thereof |
| WO2005011654A2 (en) * | 2003-07-29 | 2005-02-10 | Xenon Pharmaceuticals Inc. | Pyridyl derivatives and their use as therapeutic agents |
| KR20060037409A (ko) | 2003-07-30 | 2006-05-03 | 제논 파마슈티칼스 인크. | 피페라진 유도체 및 그의 치료제로서의 용도 |
| KR20060125885A (ko) | 2004-02-04 | 2006-12-06 | 뉴로서치 에이/에스 | 콜린 수용체 조절제로서의 디아자바이사이클릭 아릴 유도체 |
-
2006
- 2006-02-13 EP EP06708215A patent/EP1866314B1/en not_active Expired - Lifetime
- 2006-02-13 JP JP2007555581A patent/JP2008530171A/ja not_active Abandoned
- 2006-02-13 AT AT06708215T patent/ATE481407T1/de not_active IP Right Cessation
- 2006-02-13 US US11/884,345 patent/US7750011B2/en not_active Expired - Fee Related
- 2006-02-13 WO PCT/EP2006/050873 patent/WO2006087305A1/en not_active Ceased
- 2006-02-13 DE DE602006016926T patent/DE602006016926D1/de not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| ATE481407T1 (de) | 2010-10-15 |
| EP1866314A1 (en) | 2007-12-19 |
| US7750011B2 (en) | 2010-07-06 |
| DE602006016926D1 (de) | 2010-10-28 |
| US20080161314A1 (en) | 2008-07-03 |
| WO2006087305A1 (en) | 2006-08-24 |
| EP1866314B1 (en) | 2010-09-15 |
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