JP2008528886A - 温度制御された可変流体抵抗装置 - Google Patents

温度制御された可変流体抵抗装置 Download PDF

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Publication number
JP2008528886A
JP2008528886A JP2007552210A JP2007552210A JP2008528886A JP 2008528886 A JP2008528886 A JP 2008528886A JP 2007552210 A JP2007552210 A JP 2007552210A JP 2007552210 A JP2007552210 A JP 2007552210A JP 2008528886 A JP2008528886 A JP 2008528886A
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Japan
Prior art keywords
fluid
cooling
heating
flow
fluid path
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Pending
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JP2007552210A
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English (en)
Japanese (ja)
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JP2008528886A5 (enExample
Inventor
ゲルハルト，ジエフ・シー
チヤールトン，クリストフアー・シー
Original Assignee
ウオーターズ・インベストメンツ・リミテツド
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Application filed by ウオーターズ・インベストメンツ・リミテツド filed Critical ウオーターズ・インベストメンツ・リミテツド
Publication of JP2008528886A publication Critical patent/JP2008528886A/ja
Publication of JP2008528886A5 publication Critical patent/JP2008528886A5/ja
Pending legal-status Critical Current

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    • F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F16—ENGINEERING ELEMENTS AND UNITS; GENERAL MEASURES FOR PRODUCING AND MAINTAINING EFFECTIVE FUNCTIONING OF MACHINES OR INSTALLATIONS; THERMAL INSULATION IN GENERAL
    • F16K—VALVES; TAPS; COCKS; ACTUATING-FLOATS; DEVICES FOR VENTING OR AERATING
    • F16K99/00—Subject matter not provided for in other groups of this subclass
    • F16K99/0001—Microvalves
    • F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F15—FLUID-PRESSURE ACTUATORS; HYDRAULICS OR PNEUMATICS IN GENERAL
    • F15C—FLUID-CIRCUIT ELEMENTS PREDOMINANTLY USED FOR COMPUTING OR CONTROL PURPOSES
    • F15C1/00—Circuit elements having no moving parts
    • F15C1/02—Details, e.g. special constructional devices for circuits with fluid elements, such as resistances, capacitive circuit elements; devices preventing reaction coupling in composite elements ; Switch boards; Programme devices
    • F15C1/04—Means for controlling fluid streams to fluid devices, e.g. by electric signals or other signals, no mixing taking place between the signal and the flow to be controlled
    • F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F16—ENGINEERING ELEMENTS AND UNITS; GENERAL MEASURES FOR PRODUCING AND MAINTAINING EFFECTIVE FUNCTIONING OF MACHINES OR INSTALLATIONS; THERMAL INSULATION IN GENERAL
    • F16K—VALVES; TAPS; COCKS; ACTUATING-FLOATS; DEVICES FOR VENTING OR AERATING
    • F16K13/00—Other constructional types of cut-off apparatus; Arrangements for cutting-off
    • F16K13/08—Arrangements for cutting-off not used
    • F16K13/10—Arrangements for cutting-off not used by means of liquid or granular medium
    • F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F16—ENGINEERING ELEMENTS AND UNITS; GENERAL MEASURES FOR PRODUCING AND MAINTAINING EFFECTIVE FUNCTIONING OF MACHINES OR INSTALLATIONS; THERMAL INSULATION IN GENERAL
    • F16K—VALVES; TAPS; COCKS; ACTUATING-FLOATS; DEVICES FOR VENTING OR AERATING
    • F16K99/00—Subject matter not provided for in other groups of this subclass
    • F16K99/0001—Microvalves
    • F16K99/0003—Constructional types of microvalves; Details of the cutting-off member
    • F16K99/0021—No-moving-parts valves
    • F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F16—ENGINEERING ELEMENTS AND UNITS; GENERAL MEASURES FOR PRODUCING AND MAINTAINING EFFECTIVE FUNCTIONING OF MACHINES OR INSTALLATIONS; THERMAL INSULATION IN GENERAL
    • F16K—VALVES; TAPS; COCKS; ACTUATING-FLOATS; DEVICES FOR VENTING OR AERATING
    • F16K99/00—Subject matter not provided for in other groups of this subclass
    • F16K99/0001—Microvalves
    • F16K99/0003—Constructional types of microvalves; Details of the cutting-off member
    • F16K99/0032—Constructional types of microvalves; Details of the cutting-off member using phase transition or influencing viscosity
    • F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F16—ENGINEERING ELEMENTS AND UNITS; GENERAL MEASURES FOR PRODUCING AND MAINTAINING EFFECTIVE FUNCTIONING OF MACHINES OR INSTALLATIONS; THERMAL INSULATION IN GENERAL
    • F16K—VALVES; TAPS; COCKS; ACTUATING-FLOATS; DEVICES FOR VENTING OR AERATING
    • F16K99/00—Subject matter not provided for in other groups of this subclass
    • F16K99/0001—Microvalves
    • F16K99/0034—Operating means specially adapted for microvalves
    • F16K99/0036—Operating means specially adapted for microvalves operated by temperature variations
    • F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F16—ENGINEERING ELEMENTS AND UNITS; GENERAL MEASURES FOR PRODUCING AND MAINTAINING EFFECTIVE FUNCTIONING OF MACHINES OR INSTALLATIONS; THERMAL INSULATION IN GENERAL
    • F16K—VALVES; TAPS; COCKS; ACTUATING-FLOATS; DEVICES FOR VENTING OR AERATING
    • F16K99/00—Subject matter not provided for in other groups of this subclass
    • F16K2099/0082—Microvalves adapted for a particular use
    • F16K2099/0084—Chemistry or biology, e.g. "lab-on-a-chip" technology
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02—Column chromatography
    • G01N30/26—Conditioning of the fluid carrier; Flow patterns
    • G01N30/28—Control of physical parameters of the fluid carrier
    • G01N30/30—Control of physical parameters of the fluid carrier of temperature
    • G01N2030/3038—Control of physical parameters of the fluid carrier of temperature temperature control of column exit, e.g. of restrictors
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02—Column chromatography
    • G01N30/26—Conditioning of the fluid carrier; Flow patterns
    • G01N30/28—Control of physical parameters of the fluid carrier
    • G01N30/32—Control of physical parameters of the fluid carrier of pressure or speed
    • G01N2030/324—Control of physical parameters of the fluid carrier of pressure or speed speed, flow rate
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02—Column chromatography
    • G01N30/60—Construction of the column
    • G01N30/6095—Micromachined or nanomachined, e.g. micro- or nanosize
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T137/00—Fluid handling
    • Y10T137/0318—Processes
    • Y10T137/0391—Affecting flow by the addition of material or energy
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T137/00—Fluid handling
    • Y10T137/6416—With heating or cooling of the system

Landscapes

  • Engineering & Computer Science (AREA)
  • General Engineering & Computer Science (AREA)
  • Mechanical Engineering (AREA)
  • Chemical & Material Sciences (AREA)
  • Dispersion Chemistry (AREA)
  • Theoretical Computer Science (AREA)
  • Physics & Mathematics (AREA)
  • Fluid Mechanics (AREA)
  • Flow Control (AREA)
  • Fluid-Pressure Circuits (AREA)
  • Control Of Temperature (AREA)
JP2007552210A 2005-01-21 2006-01-18 温度制御された可変流体抵抗装置 Pending JP2008528886A (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US64580405P 2005-01-21 2005-01-21
PCT/US2006/001564 WO2006078634A2 (en) 2005-01-21 2006-01-18 Temperature-controlled variable fluidic resistance device

Publications (2)

Publication Number Publication Date
JP2008528886A true JP2008528886A (ja) 2008-07-31
JP2008528886A5 JP2008528886A5 (enExample) 2012-10-04

Family

ID=36692781

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2007552210A Pending JP2008528886A (ja) 2005-01-21 2006-01-18 温度制御された可変流体抵抗装置

Country Status (4)

Country Link
US (1) US20080302423A1 (enExample)
EP (1) EP1838967B1 (enExample)
JP (1) JP2008528886A (enExample)
WO (1) WO2006078634A2 (enExample)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR101573573B1 (ko) * 2013-06-07 2015-12-07 성균관대학교산학협력단 유압액추에이터의 제어장치

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DE102008032098A1 (de) * 2008-07-08 2010-02-25 Hte Ag The High Throughput Experimentation Company Teststand mit steuerbaren oder regelbaren Restriktoren
DE102008032097A1 (de) * 2008-07-08 2010-01-14 Hte Ag The High Throughput Experimentation Company Teststand mit Gruppen von Restriktoren
EP2349569A1 (de) 2008-07-08 2011-08-03 HTE Aktiengesellschaft The High Throughput Experimentation Company Teststand mit steuerbaren oder regelbaren restriktoren
EP2409204A2 (en) * 2009-03-20 2012-01-25 Avantium Holding B.v. Flow controller assembly for microfluidic applications and system for performing a plurality of experiments in parallel
WO2013028450A1 (en) 2011-08-19 2013-02-28 Waters Technologies Corporation Column manager with a multi-zone thermal system for use in liquid chromatography
CN103149949B (zh) * 2013-01-09 2016-08-03 上海空间推进研究所 一种基于帕尔贴效应的气体微流量控制器
WO2014158340A1 (en) * 2013-03-12 2014-10-02 Waters Technologies Corporation Matching thermally modulated variable restrictors to chromatography separation columns
EP2972291A4 (en) * 2013-03-12 2016-10-26 Waters Technologies Corp VARIABLE RESTRICTOR WITH THERMAL MODULATION
WO2014189738A2 (en) 2013-05-22 2014-11-27 Waters Technologies Corporation Thermally modulated variable restrictor for normalization of dynamic split ratios
CN103807502A (zh) * 2013-12-16 2014-05-21 浙江大学 热控可变流阻
WO2015183290A1 (en) 2014-05-29 2015-12-03 Agilent Technologies, Inc. Apparatus and method for introducing a sample into a separation unit of a chromatography system
US9764323B2 (en) 2014-09-18 2017-09-19 Waters Technologies Corporation Device and methods using porous media in fluidic devices
US11406916B2 (en) * 2015-03-18 2022-08-09 Francois Parmentier Method of power-efficient chromatographic separation
CN105954448B (zh) * 2016-06-22 2020-06-26 山东省计量科学研究院 一种恒温电导检测装置及检测方法
US10935149B2 (en) * 2018-03-15 2021-03-02 University Of Washington Temperature-actuated valve, fluidic device, and related methods of use

Citations (3)

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Publication number Priority date Publication date Assignee Title
JPH02134480A (ja) * 1988-11-11 1990-05-23 Hitachi Ltd 流体自体の相変化を利用した流路の開閉制御弁及び開閉制御方法
JP2002215241A (ja) * 2001-01-22 2002-07-31 National Institute Of Advanced Industrial & Technology 流量の制御方法及びそれに用いるマイクロバルブ
JP2003240757A (ja) * 2002-02-19 2003-08-27 Ngk Insulators Ltd マイクロ化学チップ

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US5316262A (en) * 1992-01-31 1994-05-31 Suprex Corporation Fluid restrictor apparatus and method for making the same
US5975856A (en) * 1997-10-06 1999-11-02 The Aerospace Corporation Method of pumping a fluid through a micromechanical valve having N-type and P-type thermoelectric elements for heating and cooling a fluid between an inlet and an outlet
DE19847952C2 (de) * 1998-09-01 2000-10-05 Inst Physikalische Hochtech Ev Fluidstromschalter
US6672076B2 (en) * 2001-02-09 2004-01-06 Bsst Llc Efficiency thermoelectrics utilizing convective heat flow
US6557575B1 (en) * 2001-11-19 2003-05-06 Waters Investments Limited Fluid flow control freeze/thaw valve for narrow bore capillaries or microfluidic devices
US6622746B2 (en) * 2001-12-12 2003-09-23 Eastman Kodak Company Microfluidic system for controlled fluid mixing and delivery
GB2414287B (en) * 2002-12-09 2007-08-15 Waters Investments Ltd Peltier based freeze-thaw valves and method of use

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH02134480A (ja) * 1988-11-11 1990-05-23 Hitachi Ltd 流体自体の相変化を利用した流路の開閉制御弁及び開閉制御方法
JP2002215241A (ja) * 2001-01-22 2002-07-31 National Institute Of Advanced Industrial & Technology 流量の制御方法及びそれに用いるマイクロバルブ
JP2003240757A (ja) * 2002-02-19 2003-08-27 Ngk Insulators Ltd マイクロ化学チップ

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR101573573B1 (ko) * 2013-06-07 2015-12-07 성균관대학교산학협력단 유압액추에이터의 제어장치

Also Published As

Publication number Publication date
WO2006078634A3 (en) 2007-08-30
EP1838967A2 (en) 2007-10-03
WO2006078634A2 (en) 2006-07-27
EP1838967B1 (en) 2017-12-13
EP1838967A4 (en) 2011-11-02
US20080302423A1 (en) 2008-12-11

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