JP2008527032A5 - - Google Patents
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- Publication number
- JP2008527032A5 JP2008527032A5 JP2007551738A JP2007551738A JP2008527032A5 JP 2008527032 A5 JP2008527032 A5 JP 2008527032A5 JP 2007551738 A JP2007551738 A JP 2007551738A JP 2007551738 A JP2007551738 A JP 2007551738A JP 2008527032 A5 JP2008527032 A5 JP 2008527032A5
- Authority
- JP
- Japan
- Prior art keywords
- synthase
- leukotriene
- activating protein
- family members
- lipoxygenase activating
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
Links
- 102000004023 5-Lipoxygenase-Activating Proteins Human genes 0.000 claims description 3
- 108090000411 5-Lipoxygenase-Activating Proteins Proteins 0.000 claims description 3
- GWNVDXQDILPJIG-NXOLIXFESA-N leukotriene C4 Chemical compound CCCCC\C=C/C\C=C/C=C/C=C/[C@H]([C@@H](O)CCCC(O)=O)SC[C@@H](C(=O)NCC(O)=O)NC(=O)CC[C@H](N)C(O)=O GWNVDXQDILPJIG-NXOLIXFESA-N 0.000 claims description 3
- 102000042256 MAPEG family Human genes 0.000 claims 2
- 108091077604 MAPEG family Proteins 0.000 claims 2
- 102100033076 Prostaglandin E synthase Human genes 0.000 claims 2
- 101710096361 Prostaglandin E synthase Proteins 0.000 claims 2
- 150000001875 compounds Chemical class 0.000 description 3
- 230000000694 effects Effects 0.000 description 2
- 206010061218 Inflammation Diseases 0.000 description 1
- 230000004054 inflammatory process Effects 0.000 description 1
- 230000005764 inhibitory process Effects 0.000 description 1
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US64455905P | 2005-01-19 | 2005-01-19 | |
| PCT/GB2006/000188 WO2006077412A1 (en) | 2005-01-19 | 2006-01-19 | Thienopyrroles useful in the treatment of inflammation |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2008527032A JP2008527032A (ja) | 2008-07-24 |
| JP2008527032A5 true JP2008527032A5 (enExample) | 2009-04-02 |
Family
ID=34956613
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2007551738A Withdrawn JP2008527032A (ja) | 2005-01-19 | 2006-01-19 | 炎症の治療に有用なチエノピロール |
Country Status (5)
| Country | Link |
|---|---|
| US (1) | US20090069384A1 (enExample) |
| EP (1) | EP1844051A1 (enExample) |
| JP (1) | JP2008527032A (enExample) |
| CA (1) | CA2594665A1 (enExample) |
| WO (1) | WO2006077412A1 (enExample) |
Families Citing this family (25)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1922149A (zh) | 2003-12-29 | 2007-02-28 | 塞普拉科公司 | 吡咯和吡唑daao抑制剂 |
| ATE501119T1 (de) | 2005-01-19 | 2011-03-15 | Biolipox Ab | Entzündungshemmende indol-derivate |
| JP2008527030A (ja) * | 2005-01-19 | 2008-07-24 | バイオリポックス エービー | 炎症の治療に有用なインドール類 |
| EP1976513B1 (en) | 2006-01-06 | 2016-08-24 | Sunovion Pharmaceuticals Inc. | Cycloalkylamines as monoamine reuptake inhibitors |
| KR101381768B1 (ko) | 2006-01-06 | 2014-04-07 | 선오비온 파마슈티컬스 인코포레이티드 | 테트랄론-기재 모노아민 재흡수 저해제 |
| PT2816024T (pt) | 2006-03-31 | 2017-10-20 | Sunovion Pharmaceuticals Inc | Aminas quirais |
| JP2009542683A (ja) * | 2006-06-30 | 2009-12-03 | セプラコア インコーポレーテッド | Ｄ−アミノ酸オキシダーゼの縮合ヘテロ環式阻害剤 |
| US7579370B2 (en) | 2006-06-30 | 2009-08-25 | Sepracor Inc. | Fused heterocycles |
| US7884124B2 (en) | 2006-06-30 | 2011-02-08 | Sepracor Inc. | Fluoro-substituted inhibitors of D-amino acid oxidase |
| US8492405B2 (en) | 2006-10-18 | 2013-07-23 | Takeda Pharmaceutical Company Limited | Glucokinase-activating fused heterocyclic compounds and methods of treating diabetes and obesity |
| US7902252B2 (en) | 2007-01-18 | 2011-03-08 | Sepracor, Inc. | Inhibitors of D-amino acid oxidase |
| WO2008151156A1 (en) | 2007-05-31 | 2008-12-11 | Sepracor Inc. | Phenyl substituted cycloalkylamines as monoamine reuptake inhibitors |
| GB0821913D0 (en) | 2008-12-02 | 2009-01-07 | Price & Co | Antibacterial compounds |
| WO2010076566A2 (en) | 2008-12-30 | 2010-07-08 | Biolipox Ab | Indoles useful in the treatment of inflammation |
| EP2473056A4 (en) | 2009-09-04 | 2013-02-13 | Glaxosmithkline Llc | CHEMICAL COMPOUNDS |
| WO2011079105A1 (en) * | 2009-12-23 | 2011-06-30 | Abbott Laboratories | Novel thienopyrrole compounds |
| GB201006846D0 (en) | 2010-04-23 | 2010-06-09 | Glaxo Group Ltd | Novel compounds |
| GB2480815A (en) * | 2010-06-01 | 2011-12-07 | Summit Corp Plc | Compounds for the treatment of clostridium difficile-associated disease |
| HRP20160397T1 (hr) | 2010-06-01 | 2016-08-12 | Summit Therapeutics Plc | Spojevi za liječenje clostridium difficile povezanih bolesti |
| EP2993175A1 (en) | 2014-09-05 | 2016-03-09 | IEO - Istituto Europeo di Oncologia Srl | Thienopyrroles as histone demethylase inhibitors |
| EP3246330A1 (en) | 2016-05-18 | 2017-11-22 | Istituto Europeo di Oncologia S.r.l. | Imidazoles as histone demethylase inhibitors |
| US10774064B2 (en) | 2016-06-02 | 2020-09-15 | Cadent Therapeutics, Inc. | Potassium channel modulators |
| BR112019014814B1 (pt) | 2017-01-23 | 2024-03-12 | Novartis Ag | Compostos, composições farmacêuticas dos mesmos e seus usos no tratamento de doenças associadas à disfunção de canais iônicos de potássio |
| AU2019366312B2 (en) | 2018-10-22 | 2025-04-24 | Novartis Ag | Crystalline forms of potassium channel modulators |
| US12070455B2 (en) * | 2021-09-10 | 2024-08-27 | Gilead Sciences, Inc. | Thienopyrrole compounds |
Family Cites Families (22)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5081138A (en) * | 1986-12-17 | 1992-01-14 | Merck Frosst Canada, Inc. | 3-hetero-substituted-n-benzyl-indoles and prevention of leucotriene synthesis therewith |
| US4960786A (en) * | 1989-04-24 | 1990-10-02 | Merrell Dow Pharmaceuticals Inc. | Excitatory amino acid antagonists |
| US5081145A (en) * | 1990-02-01 | 1992-01-14 | Merck Frosst Canada, Inc. | Indole-2-alkanoic acids compositions of and anti allergic use thereof |
| US5374615A (en) * | 1990-10-31 | 1994-12-20 | E. R. Squibb & Sons, Inc. | Indole- and benzimidazole-substituted imidazole and benzimidazole derivatives |
| US5189054A (en) * | 1990-11-02 | 1993-02-23 | Merrell Dow Pharmaceuticals Inc. | 3-amidoindolyl derivatives and pharmaceutical compositions thereof |
| US5294722A (en) * | 1992-04-16 | 1994-03-15 | E. R. Squibb & Sons, Inc. | Process for the preparation of imidazoles useful in angiotensin II antagonism |
| US5236916A (en) * | 1992-05-26 | 1993-08-17 | E. R. Squibb & Sons, Inc. | Oxadiazinone substituted indole and benzimidazole derivatives |
| TW229140B (enExample) * | 1992-06-05 | 1994-09-01 | Shell Internat Res Schappej B V | |
| WO1995033748A1 (en) * | 1994-06-09 | 1995-12-14 | Smithkline Beecham Corporation | Endothelin receptor antagonists |
| GB9716656D0 (en) * | 1997-08-07 | 1997-10-15 | Zeneca Ltd | Chemical compounds |
| GB9716657D0 (en) * | 1997-08-07 | 1997-10-15 | Zeneca Ltd | Chemical compounds |
| PT1042287E (pt) * | 1997-12-24 | 2005-08-31 | Aventis Pharma Gmbh | Derivados de indole como inibidores do factor xa |
| GB9803228D0 (en) * | 1998-02-17 | 1998-04-08 | Zeneca Ltd | Chemical compounds |
| US6828344B1 (en) * | 1998-02-25 | 2004-12-07 | Genetics Institute, Llc | Inhibitors of phospholipase enzymes |
| US6500853B1 (en) * | 1998-02-28 | 2002-12-31 | Genetics Institute, Llc | Inhibitors of phospholipase enzymes |
| GB9902452D0 (en) * | 1999-02-05 | 1999-03-24 | Zeneca Ltd | Chemical compounds |
| GB9902453D0 (en) * | 1999-02-05 | 1999-03-24 | Zeneca Ltd | Chemical compounds |
| GB9902455D0 (en) * | 1999-02-05 | 1999-03-24 | Zeneca Ltd | Chemical compounds |
| JP2001069477A (ja) * | 1999-08-31 | 2001-03-16 | Sony Corp | 番組提供システム及び番組提供方法 |
| US6353007B1 (en) * | 2000-07-13 | 2002-03-05 | Boehringer Ingelheim Pharmaceuticals, Inc. | Substituted 1-(4-aminophenyl)indoles and their use as anti-inflammatory agents |
| JP2004529855A (ja) * | 2000-10-10 | 2004-09-30 | スミスクライン ビーチャム コーポレーション | 置換インドール類、そのような置換インドール類を含む医薬組成物及びＰＰＡＲ−γ結合剤としてのそれらの使用 |
| US6630786B2 (en) * | 2001-03-30 | 2003-10-07 | Candescent Technologies Corporation | Light-emitting device having light-reflective layer formed with, or/and adjacent to, material that enhances device performance |
-
2006
- 2006-01-19 CA CA002594665A patent/CA2594665A1/en not_active Abandoned
- 2006-01-19 JP JP2007551738A patent/JP2008527032A/ja not_active Withdrawn
- 2006-01-19 EP EP06703895A patent/EP1844051A1/en not_active Withdrawn
- 2006-01-19 US US11/795,626 patent/US20090069384A1/en not_active Abandoned
- 2006-01-19 WO PCT/GB2006/000188 patent/WO2006077412A1/en not_active Ceased
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