JP2008527028A5 - - Google Patents

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Publication number
JP2008527028A5
JP2008527028A5 JP2007551726A JP2007551726A JP2008527028A5 JP 2008527028 A5 JP2008527028 A5 JP 2008527028A5 JP 2007551726 A JP2007551726 A JP 2007551726A JP 2007551726 A JP2007551726 A JP 2007551726A JP 2008527028 A5 JP2008527028 A5 JP 2008527028A5
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JP
Japan
Prior art keywords
synthase
leukotriene
activating protein
mpges
compounds
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
JP2007551726A
Other languages
English (en)
Japanese (ja)
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JP2008527028A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/GB2005/004980 external-priority patent/WO2006077365A1/en
Publication of JP2008527028A publication Critical patent/JP2008527028A/ja
Publication of JP2008527028A5 publication Critical patent/JP2008527028A5/ja
Withdrawn legal-status Critical Current

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JP2007551726A 2005-01-19 2005-12-22 炎症の治療に有用なインドール類 Withdrawn JP2008527028A (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US64451905P 2005-01-19 2005-01-19
PCT/GB2005/004980 WO2006077365A1 (en) 2005-01-19 2005-12-22 Indoles useful in the treatment of inflammation

Publications (2)

Publication Number Publication Date
JP2008527028A JP2008527028A (ja) 2008-07-24
JP2008527028A5 true JP2008527028A5 (enExample) 2009-02-19

Family

ID=34956617

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2007551726A Withdrawn JP2008527028A (ja) 2005-01-19 2005-12-22 炎症の治療に有用なインドール類

Country Status (5)

Country Link
US (1) US20090042949A1 (enExample)
EP (1) EP1838669A1 (enExample)
JP (1) JP2008527028A (enExample)
CA (1) CA2594773A1 (enExample)
WO (1) WO2006077365A1 (enExample)

Families Citing this family (29)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2008527030A (ja) * 2005-01-19 2008-07-24 バイオリポックス エービー 炎症の治療に有用なインドール類
US20080249091A1 (en) * 2005-01-19 2008-10-09 Benjamin Pelcman Indoles Useful in the Treatment of Inflammation
ATE501119T1 (de) 2005-01-19 2011-03-15 Biolipox Ab Entzündungshemmende indol-derivate
EP1854011A2 (en) * 2005-02-15 2007-11-14 Koninklijke Philips Electronics N.V. Enhancing performance of a memory unit of a data processing device by separating reading and fetching functionalities
US7977359B2 (en) 2005-11-04 2011-07-12 Amira Pharmaceuticals, Inc. 5-lipdxygenase-activating protein (FLAP) inhibitors
GB2431927B (en) 2005-11-04 2010-03-17 Amira Pharmaceuticals Inc 5-Lipoxygenase-activating protein (FLAP) inhibitors
US8399666B2 (en) 2005-11-04 2013-03-19 Panmira Pharmaceuticals, Llc 5-lipoxygenase-activating protein (FLAP) inhibitors
TW200920369A (en) 2007-10-26 2009-05-16 Amira Pharmaceuticals Inc 5-lipoxygenase activating protein (flap) inhibitor
CN102137858B (zh) 2008-05-23 2014-07-23 潘米拉制药有限责任公司 5-脂氧合酶-活化蛋白抑制剂
US8546431B2 (en) 2008-10-01 2013-10-01 Panmira Pharmaceuticals, Llc 5-lipoxygenase-activating protein (FLAP) inhibitors
WO2010076566A2 (en) 2008-12-30 2010-07-08 Biolipox Ab Indoles useful in the treatment of inflammation
JP2012530758A (ja) 2009-06-24 2012-12-06 ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング 新規化合物、医薬組成物及びそれに関する方法
NZ596445A (en) 2009-06-24 2013-04-26 Boehringer Ingelheim Int New compounds, pharmaceutical composition and methods relating thereto
JP2012211085A (ja) * 2009-08-12 2012-11-01 Kyowa Hakko Kirin Co Ltd ヘッジホッグシグナル阻害剤
GB201006846D0 (en) 2010-04-23 2010-06-09 Glaxo Group Ltd Novel compounds
WO2012145069A2 (en) * 2011-02-24 2012-10-26 The University Of Toledo Materials and methods useful to induce cell death via methuosis
JOP20130213B1 (ar) 2012-07-17 2021-08-17 Takeda Pharmaceuticals Co معارضات لمستقبلht3-5
DK2935302T3 (en) 2012-12-18 2018-08-13 Vertex Pharma MANNOS DERIVATIVES FOR TREATING BACTERIAL INFECTIONS
PL2970353T3 (pl) 2013-03-12 2018-10-31 Vertex Pharmaceuticals Incorporated Pochodne mannozy do leczenia infekcji bakteryjnych
CN106795172B (zh) 2014-09-29 2020-07-28 武田药品工业株式会社 1-(1-甲基-1h-吡唑-4-基)-n-((1r,5s,7s)-9-甲基-3-氧杂-9-氮杂双环[3.3.1]壬-7-基)-1h-吲哚-3-甲酰胺的晶型
PL3240785T3 (pl) 2014-12-29 2021-12-06 The United States Of America, As Represented By The Secretary, Department Of Health And Human Services Inhibitory drobnocząsteczkowe dehydrogenazy mleczanowej i sposoby ich wykorzystania
CN107098846B (zh) * 2016-02-26 2020-10-09 中国医学科学院药物研究所 N-酰基磺酰胺类FBPase抑制剂、其制备方法、药物组合物及用途
US10774064B2 (en) 2016-06-02 2020-09-15 Cadent Therapeutics, Inc. Potassium channel modulators
BR112019014814B1 (pt) 2017-01-23 2024-03-12 Novartis Ag Compostos, composições farmacêuticas dos mesmos e seus usos no tratamento de doenças associadas à disfunção de canais iônicos de potássio
PL3461819T3 (pl) 2017-09-29 2020-11-30 Probiodrug Ag Inhibitory cyklazy glutaminylowej
AU2019366312B2 (en) 2018-10-22 2025-04-24 Novartis Ag Crystalline forms of potassium channel modulators
WO2021040393A1 (ko) 2019-08-26 2021-03-04 국제약품 주식회사 인돌 카복사미드 유도체 및 그를 포함하는 약제학적 조성물
CN119950495A (zh) * 2020-07-24 2025-05-09 上海交通大学医学院附属瑞金医院 一种干扰整合素β3/Src相互作用的化合物的用途
CN116283946B (zh) * 2023-03-27 2024-05-07 武汉工程大学 5-(n-取代吲哚-5-基)异噁唑-3-甲酸衍生物及其合成方法和应用

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JP2004529855A (ja) * 2000-10-10 2004-09-30 スミスクライン ビーチャム コーポレーション 置換インドール類、そのような置換インドール類を含む医薬組成物及びＰＰＡＲ−γ結合剤としてのそれらの使用

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