JP2008526372A - 三次元の移植可能な骨支持体 - Google Patents
三次元の移植可能な骨支持体 Download PDFInfo
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- JP2008526372A JP2008526372A JP2007550516A JP2007550516A JP2008526372A JP 2008526372 A JP2008526372 A JP 2008526372A JP 2007550516 A JP2007550516 A JP 2007550516A JP 2007550516 A JP2007550516 A JP 2007550516A JP 2008526372 A JP2008526372 A JP 2008526372A
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
- A61F2/30—Joints
- A61F2/32—Joints for the hip
- A61F2/34—Acetabular cups
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
- A61B17/56—Surgical instruments or methods for treatment of bones or joints; Devices specially adapted therefor
- A61B17/58—Surgical instruments or methods for treatment of bones or joints; Devices specially adapted therefor for osteosynthesis, e.g. bone plates, screws, setting implements or the like
- A61B17/68—Internal fixation devices, including fasteners and spinal fixators, even if a part thereof projects from the skin
- A61B17/70—Spinal positioners or stabilisers ; Bone stabilisers comprising fluid filler in an implant
- A61B17/7097—Stabilisers comprising fluid filler in an implant, e.g. balloon; devices for inserting or filling such implants
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
- A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/04—Antineoplastic agents specific for metastasis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
Abstract
Description
本出願は、2005年1月7日に出願された米国仮特許出願第60/641,968号の米国特許法第119条(e)の下の利益を主張し、その開示は、本明細書中に参考として援用される。
哺乳動物中の疾患海綿質組織または損傷海綿質組織のために広範な範囲の処置が当該技術分野で現在知られている。海綿質またはスポンジ状骨は、小柱(ハニカム構造)および皮質骨に対して高いレベルの間隙率を有する。これら小柱間のスペースは、スポンジ状骨を養う血管を含む赤色骨髄で充填されている。スポンジ状骨は、骨盤、肋骨、胸骨、脊椎、頭蓋、および腕骨および脚骨の端部の骨中に見出される。
本発明は、疾患または損傷骨組織を処置する方法に関し、処置されるべき骨組織中の内部領域を選択する工程、この処置されるべき骨組織の内部領域中にデバイスを挿入する工程、および処置の間にこのデバイスを用いて骨組織を内部で支持する工程を包含する。
本発明は、整形外科の外科用デバイスおよび技法の分野に関する。本発明の処置の方法は、除去可能なファスナー、好ましくはスクリューデバイスによって、好ましくは離脱可能な半伸展性構造に連結されるカテーテル67を用いる工程を含む。このファスナーは、カテーテル67を半伸展性構造49に離脱可能に連結し、そして半伸展性デバイス49をカテーテル67に連結し得、そしてこの半伸展性デバイス49をカテーテル67から外し得る。
調節され得る。あるいは、適切な温度は、選択された骨支持材料83の触媒反応によって達成され得る。骨組織17の再処置は、本明細書中に記載される選択された処置レジメの引き続く引き抜き、および再導入によってなされ得る。
Claims (29)
- 疾患または損傷骨組織を処置する方法であって:
処置されるべき骨組織中の内部領域を選択する工程;
該処置されるべき骨組織の内部領域中にデバイスを挿入する工程;および
処置の間に該デバイスを用いて該骨組織を内部で支持する工程、を包含する、方法。 - 最小侵襲的画像案内技法を用いて、前記内部領域を選択する工程をさらに包含する、請求項1に記載の方法。
- 前記デバイスが、置換可能である、請求項1に記載の方法。
- 前記デバイスが、前記骨組織を支持し得る構造を有するカテーテルである、請求項3に記載の方法。
- 前記カテーテルが、拡大可能な三次元半伸展性構造およびファスナーを備え、そしてここで、該ファスナーが、該カテーテルを該半伸展性構造に離脱可能に連結する、請求項4に記載の方法。
- 前記カテーテルが、前記半伸展性構造から離脱可能である、請求項5に記載の方法。
- 前記カテーテルがそれを通る少なくとも1つの内部通路を規定する本体を有し、前記半伸展性構造が内部スペースを規定し、そして該半伸展性構造が、該カテーテルの内部通路と該半伸展性構造の内部スペースとの間の連通を可能にするシール可能なポートを備える、請求項6に記載の方法。
- 前記半伸展性構造中に、前記カテーテル内の通路を通り、前記シール可能なポートを通り、そして該構造の内部スペース中に骨支持材料を注入する工程をさらに包含し、それによって、前記骨組織内の三次元半伸展性構造を拡大する、請求項7に記載の方法。
- 前記骨支持材料が硬化し得、前記骨組織のための永久的支持を提供する、請求項8に記載の方法。
- さらに:放射線学的処置材料を前記骨支持材料と混合して混合物を形成し、そして該混合物を前記半伸展性構造中に導入する工程を包含し、ここで、該半伸展性構造が、処置されるべき領域を該放射線学的処置材料に曝すことを容易にし得る、請求項8に記載の方法。
- さらに、前記放射線学的処置が枯渇されるとき、前記半伸展性構造を、第2の置換三次元半伸展性構造で置換する工程をさらに包含する、請求項10に記載の方法。
- 前記放射線学的処置が時間放出医薬であり、そして該医薬が前記半伸展性構造を脱出し得、そして該半伸展性構造の表面を被覆する、請求項10に記載の方法。
- 前記半伸展性構造が半透過性材料を含み、そして前記医薬が該半透過性材料を通って拡散し、疾患または損傷を処置する、請求項10に記載の方法。
- 前記半透過性材料が、ポリマー材料、再吸収可能合成材料、縫合糸材料、ニチノール、およびそれらの組み合わせからなる群から選択される、請求項13に記載の方法。
- 前記材料が、生体適合性のニチノールである、請求項14に記載の方法。
- 前記ポリマー材料が、ポリエステル、ポリエチレン、ポリ乳酸、およびそれらの組み合わせからなる群から選択される、請求項14に記載の方法。
- 前記疾患または損傷が、骨粗鬆症、骨粗鬆症で骨折した骨幹端および骨端骨、骨粗鬆症椎骨本体、腫瘍に起因する椎骨本体の骨折、円形細胞腫瘍、長骨の骨端の虚血壊死、近位大腿骨、遠位大腿骨および/または近位上腕骨の虚血壊死、内分泌状態、転移性腫瘍から生じる欠陥、およびそれらの組み合わせからなる群から選択される、請求項13に記載の方法。
- 前記半伸展性構造が前記カテーテルから離脱可能である請求項8に記載の方法であって:
該カテーテルを該半伸展性構造から離脱する工程;
前記シール可能なポートをシールする工程;および
加圧環境にある該構造内に前記骨支持材料を維持し、それによって、該骨支持材料が該構造内から押出すことを防ぎ、前記骨組織の一時的支持を提供する工程をさらに包含する、方法。 - 前記骨支持材料が、液体、ペースト、ゲル、セメント、およびそれらの組み合わせからなる群から選択される、請求項8に記載の方法。
- 前記骨支持材料が、セメントである、請求項19に記載の方法。
- 前記セメントが、ポリメチルメタクリレート、デキストラン、ポリエチレン、カーボンファイバー、ポリビニルアルコール、およびポリ(エチレンテレフタレート)からなる群から選択される材料を含む、請求項20に記載の方法。
- 前記骨支持材料が、液体である、請求項9に記載の方法。
- さらに:前記カテーテルを前記シール可能なポートに再取り付けする工程;および
前記骨支持材料を引き抜く工程、をさらに包含する、請求項18に記載の方法。 - 疾患または損傷骨を処置するためのデバイスであって:
カテーテルであって、それを通る少なくとも1つの内部通路を規定する主本体を備えるカテーテル;
拡大可能な半伸展性構造であって、内部スペースを規定する半伸展性構造;および
離脱可能なファスナーであって、該カテーテルを該半伸展性構造に離脱可能に連結するファスナーを備える、デバイス。 - シール可能なポートをさらに備え、該ポートを通って前記カテーテルの内部通路が前記半伸展性構造の内部スペースと連通する、請求項24に記載のデバイス。
- 前記カテーテルが、前記半伸展性構造から離脱可能である、請求項25に記載のデバイス。
- 前記カテーテルが、骨支持材料を受容し得る、請求項26に記載のデバイス。
- 前記ファスナーが、スクリューデバイスである、請求項24に記載のデバイス。
- 前記半伸展性構造が、骨中の処置されるべき領域に適合するために拡大し得る請求項24に記載のデバイス。
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
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US64196805P | 2005-01-07 | 2005-01-07 | |
US60/641,968 | 2005-01-07 | ||
PCT/US2006/000534 WO2006074410A2 (en) | 2005-01-07 | 2006-01-09 | Three-dimensional implantable bone support |
Publications (2)
Publication Number | Publication Date |
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JP2008526372A true JP2008526372A (ja) | 2008-07-24 |
JP5159320B2 JP5159320B2 (ja) | 2013-03-06 |
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Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
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JP2007550516A Active JP5159320B2 (ja) | 2005-01-07 | 2006-01-09 | 三次元の移植可能な骨支持体 |
Country Status (12)
Country | Link |
---|---|
US (1) | US20060155296A1 (ja) |
EP (1) | EP1833426A4 (ja) |
JP (1) | JP5159320B2 (ja) |
KR (1) | KR101303583B1 (ja) |
CN (1) | CN101123920B (ja) |
AR (1) | AR055833A1 (ja) |
AU (1) | AU2006203902B2 (ja) |
BR (1) | BRPI0606473A2 (ja) |
CA (1) | CA2592782C (ja) |
PE (1) | PE20060861A1 (ja) |
TW (1) | TW200640433A (ja) |
WO (1) | WO2006074410A2 (ja) |
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- 2006-01-09 EP EP06717700A patent/EP1833426A4/en not_active Withdrawn
- 2006-01-09 BR BRPI0606473-6A patent/BRPI0606473A2/pt not_active Application Discontinuation
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- 2006-01-09 CA CA2592782A patent/CA2592782C/en active Active
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- 2006-01-09 CN CN2006800019105A patent/CN101123920B/zh not_active Expired - Fee Related
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JP2014506809A (ja) * | 2011-01-17 | 2014-03-20 | ノビタ・セラピューティクス・リミテッド・ライアビリティ・カンパニー | ブロックステントデバイスおよび使用方法 |
JP2014508574A (ja) * | 2011-01-17 | 2014-04-10 | ノビタ・セラピューティクス・リミテッド・ライアビリティ・カンパニー | 離脱式金属バルーン送達デバイスおよび方法 |
JP2014509881A (ja) * | 2011-01-17 | 2014-04-24 | ノビタ・セラピューティクス・リミテッド・ライアビリティ・カンパニー | ボールステントデバイスおよび使用方法 |
JP2011115631A (ja) * | 2011-03-15 | 2011-06-16 | Hiromi Hayashi | 人工関節 |
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AU2006203902A1 (en) | 2006-07-13 |
JP5159320B2 (ja) | 2013-03-06 |
WO2006074410A3 (en) | 2007-10-18 |
TW200640433A (en) | 2006-12-01 |
CA2592782C (en) | 2012-03-27 |
AU2006203902B2 (en) | 2011-09-22 |
WO2006074410A2 (en) | 2006-07-13 |
KR20070114113A (ko) | 2007-11-29 |
CA2592782A1 (en) | 2006-07-13 |
BRPI0606473A2 (pt) | 2009-06-30 |
PE20060861A1 (es) | 2006-10-25 |
EP1833426A2 (en) | 2007-09-19 |
EP1833426A4 (en) | 2013-01-23 |
CN101123920B (zh) | 2012-09-26 |
US20060155296A1 (en) | 2006-07-13 |
AR055833A1 (es) | 2007-09-12 |
CN101123920A (zh) | 2008-02-13 |
KR101303583B1 (ko) | 2013-09-11 |
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