JP2008516996A - 抗ウイルス性オリゴヌクレオチド - Google Patents

抗ウイルス性オリゴヌクレオチド Download PDF

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Publication number
JP2008516996A
JP2008516996A JP2007537092A JP2007537092A JP2008516996A JP 2008516996 A JP2008516996 A JP 2008516996A JP 2007537092 A JP2007537092 A JP 2007537092A JP 2007537092 A JP2007537092 A JP 2007537092A JP 2008516996 A JP2008516996 A JP 2008516996A
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JP
Japan
Prior art keywords
oligonucleotide
virus
antiviral
rep
oligonucleotides
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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Application number
JP2007537092A
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English (en)
Japanese (ja)
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JP2008516996A5 (fr
Inventor
アンドリュー バイヤン
ジャン−マルク ジュトー
Original Assignee
レプリコール インコーポレーティッド
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Filing date
Publication date
Priority claimed from US10/969,812 external-priority patent/US20050196382A1/en
Application filed by レプリコール インコーポレーティッド filed Critical レプリコール インコーポレーティッド
Publication of JP2008516996A publication Critical patent/JP2008516996A/ja
Publication of JP2008516996A5 publication Critical patent/JP2008516996A5/ja
Withdrawn legal-status Critical Current

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    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2121/00Preparations for use in therapy
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2710/00MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
    • C12N2710/00011Details
    • C12N2710/16011Herpesviridae
    • C12N2710/16611Simplexvirus, e.g. human herpesvirus 1, 2
    • C12N2710/16622New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2760/00MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
    • C12N2760/00011Details
    • C12N2760/16011Orthomyxoviridae
    • C12N2760/16111Influenzavirus A, i.e. influenza A virus
    • C12N2760/16122New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Virology (AREA)
  • Biochemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
JP2007537092A 2004-10-19 2005-10-19 抗ウイルス性オリゴヌクレオチド Withdrawn JP2008516996A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US10/969,812 US20050196382A1 (en) 2002-09-13 2004-10-19 Antiviral oligonucleotides targeting viral families
US66898305P 2005-04-07 2005-04-07
PCT/CA2005/001623 WO2006042418A1 (fr) 2004-10-19 2005-10-19 Oligonucleotides antiviraux

Publications (2)

Publication Number Publication Date
JP2008516996A true JP2008516996A (ja) 2008-05-22
JP2008516996A5 JP2008516996A5 (fr) 2008-08-21

Family

ID=36202655

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2007537092A Withdrawn JP2008516996A (ja) 2004-10-19 2005-10-19 抗ウイルス性オリゴヌクレオチド

Country Status (5)

Country Link
EP (1) EP1802643A1 (fr)
JP (1) JP2008516996A (fr)
AU (1) AU2005297376A1 (fr)
CA (1) CA2584207A1 (fr)
WO (1) WO2006042418A1 (fr)

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20150013309A (ko) * 2012-05-18 2015-02-04 레플리코르 인코포레이티드 올리고뉴클레오타이드 킬레이트 복합체-폴리펩타이드 조성물 및 방법
JP2015517503A (ja) * 2012-05-18 2015-06-22 レプリコール インコーポレーティッド オリゴヌクレオチドキレート錯体方法
JP2016520312A (ja) * 2013-05-22 2016-07-14 アルナイラム ファーマシューティカルズ, インコーポレイテッドAlnylam Pharmaceuticals, Inc. SERPINA1 iRNA組成物およびその使用方法

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PL2308514T3 (pl) 2007-03-23 2013-11-29 To Bbb Holding B V Koniugaty do ukierunkowanego dostarczania leku poprzez barierę krew-mózg
WO2016030863A1 (fr) * 2014-08-29 2016-03-03 Glaxosmithkline Intellectual Property Development Limited Composés et méthodes de traitement des infections virales
TWI788312B (zh) 2016-11-23 2023-01-01 美商阿尼拉製藥公司 絲胺酸蛋白酶抑制因子A1 iRNA組成物及其使用方法
US11166976B2 (en) 2018-11-08 2021-11-09 Aligos Therapeutics, Inc. S-antigen transport inhibiting oligonucleotide polymers and methods
WO2021119325A1 (fr) * 2019-12-12 2021-06-17 Aligos Therapeutics, Inc. Polymères oligonucléotidiques inhibant le transport de l'antigène s et méthodes
WO2022109129A1 (fr) * 2020-11-20 2022-05-27 Aligos Therapeutics, Inc. Conjugués de polymères oligonucléotidiques inhibant le transport de l'antigène s présentant un ciblage amélioré du foie
WO2022229350A2 (fr) 2021-04-30 2022-11-03 Tirmed Pharma Ab Oligonucléotides monocaténaires pouvant être utilisés dans le traitement médical et/ou la prophylaxie d'infections virales
EP4108771A1 (fr) * 2021-06-24 2022-12-28 Johann-Wolfgang-Goethe-Universität Frankfurt am Main Oligonucléotides contenant un quadruplex g pour le traitement préventif et thérapeutique

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1993004204A1 (fr) * 1991-08-23 1993-03-04 Isis Pharmaceuticals, Inc. Derandomisation synthetique de fragments oligomeres
IL107150A0 (en) * 1992-09-29 1993-12-28 Isis Pharmaceuticals Inc Oligonucleotides having a conserved g4 core sequence
EP2330194A3 (fr) * 2002-09-13 2011-10-12 Replicor, Inc. Oligonucléotides antiviraux non complémentaires de séquence

Cited By (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20150013309A (ko) * 2012-05-18 2015-02-04 레플리코르 인코포레이티드 올리고뉴클레오타이드 킬레이트 복합체-폴리펩타이드 조성물 및 방법
JP2015517504A (ja) * 2012-05-18 2015-06-22 レプリコール インコーポレーティッド オリゴヌクレオチドキレート錯体−ポリペプチド組成物および方法
JP2015517503A (ja) * 2012-05-18 2015-06-22 レプリコール インコーポレーティッド オリゴヌクレオチドキレート錯体方法
JP2018058853A (ja) * 2012-05-18 2018-04-12 レプリコール インコーポレーティッド オリゴヌクレオチドキレート錯体方法
KR102068109B1 (ko) * 2012-05-18 2020-01-21 레플리코르 인코포레이티드 올리고뉴클레오타이드 킬레이트 복합체-폴리펩타이드 조성물 및 방법
JP2016520312A (ja) * 2013-05-22 2016-07-14 アルナイラム ファーマシューティカルズ, インコーポレイテッドAlnylam Pharmaceuticals, Inc. SERPINA1 iRNA組成物およびその使用方法
JP2019107029A (ja) * 2013-05-22 2019-07-04 アルナイラム ファーマシューティカルズ, インコーポレイテッドAlnylam Pharmaceuticals, Inc. SERPINA1 iRNA組成物およびその使用方法
JP2021191278A (ja) * 2013-05-22 2021-12-16 アルナイラム ファーマシューティカルズ, インコーポレイテッドAlnylam Pharmaceuticals, Inc. SERPINA1 iRNA組成物およびその使用方法

Also Published As

Publication number Publication date
CA2584207A1 (fr) 2006-04-27
WO2006042418A9 (fr) 2007-05-31
EP1802643A1 (fr) 2007-07-04
WO2006042418A1 (fr) 2006-04-27
AU2005297376A1 (en) 2006-04-27

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