JP2008514551A - ジベンゾジアゼピノンアナログ、その製造方法及び医薬品としての使用 - Google Patents

ジベンゾジアゼピノンアナログ、その製造方法及び医薬品としての使用 Download PDF

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Publication number
JP2008514551A
JP2008514551A JP2007532739A JP2007532739A JP2008514551A JP 2008514551 A JP2008514551 A JP 2008514551A JP 2007532739 A JP2007532739 A JP 2007532739A JP 2007532739 A JP2007532739 A JP 2007532739A JP 2008514551 A JP2008514551 A JP 2008514551A
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JP
Japan
Prior art keywords
compound
pharmaceutically acceptable
compound according
prodrug
compounds
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2007532739A
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English (en)
Japanese (ja)
Other versions
JP2008514551A5 (de
Inventor
ジェイムス ビー. マックアルパイン
アルジュン エイチ. バンスコタ
Original Assignee
エコピア バイオサイエンシーズ インク
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Priority claimed from US10/951,436 external-priority patent/US7186713B2/en
Priority claimed from CA 2497031 external-priority patent/CA2497031A1/en
Application filed by エコピア バイオサイエンシーズ インク filed Critical エコピア バイオサイエンシーズ インク
Publication of JP2008514551A publication Critical patent/JP2008514551A/ja
Publication of JP2008514551A5 publication Critical patent/JP2008514551A5/ja
Pending legal-status Critical Current

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Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D243/00Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms
    • C07D243/06Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4
    • C07D243/10Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems
    • C07D243/38[b, e]- or [b, f]-condensed with six-membered rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
JP2007532739A 2004-09-27 2005-09-26 ジベンゾジアゼピノンアナログ、その製造方法及び医薬品としての使用 Pending JP2008514551A (ja)

Applications Claiming Priority (6)

Application Number Priority Date Filing Date Title
US10/951,436 US7186713B2 (en) 2003-01-21 2004-09-27 Farnesyl dibenzodiazepinones and methods of treating cancer using same
US62565304P 2004-11-08 2004-11-08
US64738105P 2005-01-28 2005-01-28
CA 2497031 CA2497031A1 (en) 2004-11-08 2005-02-11 Farnesyl dibenzodiazepinones, processes for their production and their use as pharmaceuticals
US70147205P 2005-07-22 2005-07-22
PCT/CA2005/001467 WO2006034574A1 (en) 2004-09-27 2005-09-26 Dibenzodiazepinone analogues, processes for their production and their use as pharmaceuticals

Publications (2)

Publication Number Publication Date
JP2008514551A true JP2008514551A (ja) 2008-05-08
JP2008514551A5 JP2008514551A5 (de) 2008-11-13

Family

ID=36118533

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2007532739A Pending JP2008514551A (ja) 2004-09-27 2005-09-26 ジベンゾジアゼピノンアナログ、その製造方法及び医薬品としての使用

Country Status (4)

Country Link
EP (1) EP1809612A4 (de)
JP (1) JP2008514551A (de)
AU (1) AU2005289317A1 (de)
WO (1) WO2006034574A1 (de)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2008542308A (ja) * 2005-06-02 2008-11-27 タリオン ファーマシューティカルズ インク. ファルネシルジベンゾジアゼピノン製剤
US20090170837A1 (en) * 2007-08-17 2009-07-02 Thallion Pharmaceuticals Inc. Methods for treating ras driven cancer in a subject
JP5068209B2 (ja) * 2008-03-27 2012-11-07 学校法人金城学院 高速向流クロマトグラフィーによるターメリックパウダー(ウコン粉末)からのクルクミン類の分離精製法

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2466340A1 (en) * 2003-01-21 2004-08-09 Ecopia Biosciences Inc. Farnesyl dibenzodiazepinone, processes for its production and its use as a pharmaceutical
WO2006128288A1 (en) * 2005-06-02 2006-12-07 Thallion Pharmaceuticals Inc. Formulation comprising farnesyl dibenzodiazepinone and a pharmaceutically acceptable surfactant

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5541181A (en) * 1994-05-26 1996-07-30 Bristol-Myers Squibb Company Compound produced by a strain of micromonospora

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2466340A1 (en) * 2003-01-21 2004-08-09 Ecopia Biosciences Inc. Farnesyl dibenzodiazepinone, processes for its production and its use as a pharmaceutical
WO2006128288A1 (en) * 2005-06-02 2006-12-07 Thallion Pharmaceuticals Inc. Formulation comprising farnesyl dibenzodiazepinone and a pharmaceutically acceptable surfactant

Also Published As

Publication number Publication date
EP1809612A4 (de) 2009-05-27
WO2006034574A1 (en) 2006-04-06
AU2005289317A1 (en) 2006-04-06
EP1809612A1 (de) 2007-07-25

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