JP2008508313A5 - - Google Patents
Download PDFInfo
- Publication number
- JP2008508313A5 JP2008508313A5 JP2007523858A JP2007523858A JP2008508313A5 JP 2008508313 A5 JP2008508313 A5 JP 2008508313A5 JP 2007523858 A JP2007523858 A JP 2007523858A JP 2007523858 A JP2007523858 A JP 2007523858A JP 2008508313 A5 JP2008508313 A5 JP 2008508313A5
- Authority
- JP
- Japan
- Prior art keywords
- antigen
- molecular complex
- human
- antibody
- cell
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US10/903,191 US9259459B2 (en) | 2003-01-31 | 2004-07-30 | Antibody vaccine conjugates and uses therefor |
| US10/903,191 | 2004-07-30 | ||
| PCT/US2005/027044 WO2006073493A2 (en) | 2004-07-30 | 2005-07-28 | Vaccine conjugates comprising a monoclonal antibody binding to human dentritic cells and beta human chronic gonadotropin |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2008508313A JP2008508313A (ja) | 2008-03-21 |
| JP2008508313A5 true JP2008508313A5 (enExample) | 2008-09-18 |
| JP4846718B2 JP4846718B2 (ja) | 2011-12-28 |
Family
ID=36647929
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2007523858A Expired - Fee Related JP4846718B2 (ja) | 2004-07-30 | 2005-07-28 | ヒト樹状細胞に結合するモノクローナル抗体とβヒト絨毛性性腺刺激ホルモンを含むワクチン結合体 |
Country Status (7)
| Country | Link |
|---|---|
| US (3) | US9259459B2 (enExample) |
| EP (1) | EP1789093B1 (enExample) |
| JP (1) | JP4846718B2 (enExample) |
| CN (1) | CN101039700B (enExample) |
| AU (1) | AU2005323472B2 (enExample) |
| CA (1) | CA2575248A1 (enExample) |
| WO (1) | WO2006073493A2 (enExample) |
Families Citing this family (24)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2007103048A2 (en) * | 2006-03-01 | 2007-09-13 | Regents Of The University Of Colorado | Tlr agonist (flagellin)/cd40 agonist/antigen protein and dna conjugates and use thereof for inducing synergistic enhancement in immunity |
| MX2008013993A (es) * | 2006-05-03 | 2009-05-11 | Univ Colorado | Combinación adyuvante sinergistica de anticuerpo agonista de cd40/interferona tipo 1, conjugados que la contienen y uso de los mismos como un terapeutico para aumentar la inmunidad celular. |
| ES2429407T3 (es) * | 2006-06-08 | 2013-11-14 | Chugai Seiyaku Kabushiki Kaisha | Agente preventivo o remedio para enfermedades inflamatorias |
| WO2008039432A1 (en) * | 2006-09-26 | 2008-04-03 | Alexion Pharmaceuticals, Inc. | Compositions and methods for enhancing an adjuvant |
| MX2009003306A (es) | 2006-10-02 | 2009-04-23 | Medarex Inc | Anticuerpos humanos que se unen a cxcr4 y sus usos. |
| US8426565B2 (en) * | 2007-08-30 | 2013-04-23 | Walter And Eliza Hall Institute Of Medical Research | Dendritic cell marker and uses thereof |
| DK2406289T3 (en) * | 2009-03-10 | 2017-05-01 | Baylor Res Inst | ANTIGEN PRESENTING CELL TARGETED ANTIVIRUS VACCINES |
| BR112012028522A2 (pt) * | 2010-05-07 | 2016-07-19 | Baylor Res Inst | sensibilização cruzada mediada por imunorreceptores de células dendríticas (dcir) de células t humanas cd8+ |
| KR20130108295A (ko) * | 2010-08-13 | 2013-10-02 | 베일러 리서치 인스티튜트 | 항원-제시 세포에 항체에 대한 보조제를 직접 표적화함을 기초로 하는 신규 백신 보조제 |
| JP2013542928A (ja) * | 2010-09-30 | 2013-11-28 | フランバックス ソチエタ レスポンサビリタ リミテ | ビロソーム粒子の生成 |
| CN112587671A (zh) | 2012-07-18 | 2021-04-02 | 博笛生物科技有限公司 | 癌症的靶向免疫治疗 |
| DK3092256T3 (da) | 2014-01-10 | 2022-06-20 | Birdie Biopharmaceuticals Inc | Forbindelser og sammensætninger til immunterapi |
| CN121243402A (zh) | 2014-07-09 | 2026-01-02 | 博笛生物科技有限公司 | 用于治疗肿瘤的抗-pd-l1组合 |
| CN112587672A (zh) | 2014-09-01 | 2021-04-02 | 博笛生物科技有限公司 | 用于治疗肿瘤的抗-pd-l1结合物 |
| EP3368092B9 (en) | 2015-10-29 | 2020-07-29 | Novartis AG | Antibody conjugates comprising toll-like receptor agonist |
| CN115350279A (zh) | 2016-01-07 | 2022-11-18 | 博笛生物科技有限公司 | 用于治疗肿瘤的抗-her2组合 |
| CN106943597A (zh) | 2016-01-07 | 2017-07-14 | 博笛生物科技(北京)有限公司 | 用于治疗肿瘤的抗-egfr组合 |
| CN106943596A (zh) | 2016-01-07 | 2017-07-14 | 博笛生物科技(北京)有限公司 | 用于治疗肿瘤的抗-cd20组合 |
| CN116284392A (zh) | 2016-03-10 | 2023-06-23 | 艾科赛扬制药股份有限公司 | 活化素2型受体结合蛋白及其用途 |
| CN108794467A (zh) | 2017-04-27 | 2018-11-13 | 博笛生物科技有限公司 | 2-氨基-喹啉衍生物 |
| CA3067268A1 (en) | 2017-06-23 | 2018-12-27 | Birdie Biopharmaceuticals, Inc. | Crystalline resiquimod monosulfate anhydrate and its preparation and uses |
| CN109517066A (zh) * | 2018-11-08 | 2019-03-26 | 深圳容金科技有限公司 | 一种抗hCGβ-CTP单克隆抗体及其制备方法 |
| CN114836389B (zh) * | 2022-07-05 | 2022-09-30 | 山东硕景生物科技有限公司 | 分泌抗hcg单克隆抗体的杂交瘤细胞株、抗hcg单克隆抗体及应用 |
| WO2025250964A1 (en) * | 2024-05-31 | 2025-12-04 | Aro Biotherapeutics Company | Cd206 binding human fibronectin type iii protein scaffolds |
Family Cites Families (45)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4474893A (en) * | 1981-07-01 | 1984-10-02 | The University of Texas System Cancer Center | Recombinant monoclonal antibodies |
| GB8422238D0 (en) | 1984-09-03 | 1984-10-10 | Neuberger M S | Chimeric proteins |
| US4954617A (en) * | 1986-07-07 | 1990-09-04 | Trustees Of Dartmouth College | Monoclonal antibodies to FC receptors for immunoglobulin G on human mononuclear phagocytes |
| US4946778A (en) * | 1987-09-21 | 1990-08-07 | Genex Corporation | Single polypeptide chain binding molecules |
| US5260203A (en) * | 1986-09-02 | 1993-11-09 | Enzon, Inc. | Single polypeptide chain binding molecules |
| ATE243754T1 (de) * | 1987-05-21 | 2003-07-15 | Micromet Ag | Multifunktionelle proteine mit vorbestimmter zielsetzung |
| GB8823869D0 (en) * | 1988-10-12 | 1988-11-16 | Medical Res Council | Production of antibodies |
| ATE158021T1 (de) | 1990-08-29 | 1997-09-15 | Genpharm Int | Produktion und nützung nicht-menschliche transgentiere zur produktion heterologe antikörper |
| WO1993012227A1 (en) | 1991-12-17 | 1993-06-24 | Genpharm International, Inc. | Transgenic non-human animals capable of producing heterologous antibodies |
| US6300129B1 (en) | 1990-08-29 | 2001-10-09 | Genpharm International | Transgenic non-human animals for producing heterologous antibodies |
| AU9040591A (en) | 1990-11-06 | 1992-05-26 | Children's Medical Center Corporation | Soluble mannose receptor peptides |
| GB9117522D0 (en) | 1991-08-14 | 1991-10-02 | Medical Res Council | Ligands for dendritic cells, their uses and production |
| GB9223377D0 (en) | 1992-11-04 | 1992-12-23 | Medarex Inc | Humanized antibodies to fc receptors for immunoglobulin on human mononuclear phagocytes |
| AU8068694A (en) * | 1993-11-04 | 1995-05-23 | Canterbury Health Limited | Dendritic cell-specific antibodies and methods for their preparation |
| WO1995015340A1 (en) | 1993-12-03 | 1995-06-08 | The Board Of Trustees Of Leland Stanford Junior University | Monoclonal antibodies to antigens expressed by human dendritic cells |
| US5541110A (en) * | 1994-05-17 | 1996-07-30 | Bristol-Myers Squibb | Cloning and expression of a gene encoding bryodin 1 from Bryonia dioica |
| US5698679A (en) * | 1994-09-19 | 1997-12-16 | National Jewish Center For Immunology And Respiratory Medicine | Product and process for targeting an immune response |
| JPH10513350A (ja) | 1995-01-31 | 1998-12-22 | ザ ロックフェラー ユニヴァーシティ | DEC(樹状細胞及び上皮細胞、205 kDa)の同定、C型レクチンドメインを有するレセプター、DECをコードする核酸、及びこれらの使用 |
| US20040258688A1 (en) * | 1995-01-31 | 2004-12-23 | Daniel Hawiger | Enhanced antigen delivery and modulation of the immune response therefrom |
| US20020187131A1 (en) * | 1995-01-31 | 2002-12-12 | Daniel Hawiger | Enhanced antigen delivery and modulation of the immune response therefrom |
| US5869057A (en) * | 1995-06-07 | 1999-02-09 | Rock; Edwin P. | Recombinant vaccines to break self-tolerance |
| US6440418B1 (en) * | 1995-11-07 | 2002-08-27 | Idec Pharmaceuticals Corporation | Methods of treating autoimmune diseases with gp39-specific antibodies |
| US6080409A (en) * | 1995-12-28 | 2000-06-27 | Dendreon Corporation | Immunostimulatory method |
| US6117977A (en) * | 1996-04-24 | 2000-09-12 | Genentech, Inc. | Type C lectins |
| JP2000512490A (ja) * | 1996-05-29 | 2000-09-26 | デレク ナイジェル ジョン ハート | 樹状細胞のレセプター |
| US5922845A (en) * | 1996-07-11 | 1999-07-13 | Medarex, Inc. | Therapeutic multispecific compounds comprised of anti-Fcα receptor antibodies |
| WO1998015579A1 (en) | 1996-10-09 | 1998-04-16 | Canterbury Health Limited | Dendritic cell-specific antibodies |
| KR20010021597A (ko) * | 1997-07-09 | 2001-03-15 | 둘락 노먼 씨. | 분리된 덴드라이틱 세포막 단백질 유전자 |
| EP1027063B1 (en) | 1997-09-29 | 2009-02-18 | The Macfarlane Burnet Institute For Medical Research And Public Health Ltd | Mannose receptor bearing cell line and antigen composition |
| WO1999024554A2 (en) | 1997-11-12 | 1999-05-20 | University Of Pittsburgh | Isolation, characterization, and identification of dendritic like cells and methods of using same |
| CA2323083A1 (en) | 1998-03-17 | 1999-09-23 | Schering Corporation | Isolated mammalian membrane protein genes and related reagents |
| ES2230848T3 (es) | 1998-04-28 | 2005-05-01 | Smithkline Beecham Corporation | Anticuerpos monoclonales con inmunogenicidad reducida. |
| EP1078060B1 (en) | 1998-05-11 | 2007-01-10 | E.P. Prof. Dr. Rieber | Antibodies to dendritic cells and human dendritic cell populations and uses thereof |
| AU4954899A (en) | 1998-06-26 | 2000-01-17 | Trustees Of Dartmouth College | Methods and compositions for modulating antigen-specific immunological (humoral)responses by targeting such antigen to apcs in conjunction with anti-cd40 ligan d administration |
| KR100295558B1 (ko) | 1998-06-27 | 2001-07-12 | 김기태 | 1차면역세포들중덴드리틱세포(dendriticcell)표면에특이하게작용하는단클론항체3-6-a |
| EP0997476A3 (en) | 1998-09-25 | 2000-07-19 | Schering-Plough | Antibodies to a mammalian Langerhans cell antigen and their uses |
| EP1046651A1 (en) | 1999-04-19 | 2000-10-25 | Koninklijke Universiteit Nijmegen | Composition and method for modulating dendritic cell-T interaction |
| US6794132B2 (en) | 1999-10-02 | 2004-09-21 | Biosite, Inc. | Human antibodies |
| KR100881471B1 (ko) * | 2000-05-08 | 2009-02-05 | 셀덱스 쎄라퓨틱스, 인크. | 수상세포에 대한 인간 모노클로날 항체 |
| US7560534B2 (en) | 2000-05-08 | 2009-07-14 | Celldex Research Corporation | Molecular conjugates comprising human monoclonal antibodies to dendritic cells |
| GB0105360D0 (en) * | 2001-03-03 | 2001-04-18 | Glaxo Group Ltd | Chimaeric immunogens |
| US20060088520A1 (en) * | 2001-11-30 | 2006-04-27 | Crucell Holland B.V. | Antigen presenting cell targeting conjugate, an antigen presenting cell contacted with such conjugate, their use for vaccination or as medicament, and methods for their production or generation |
| US8029803B2 (en) * | 2002-06-20 | 2011-10-04 | Paladin Labs, Inc. | Chimeric antigens for eliciting an immune response |
| WO2004026326A2 (en) | 2002-09-20 | 2004-04-01 | Stichting Katholieke Universiteit | Antigen uptake receptor for candida albicans on dendritic cells |
| US20050004144A1 (en) * | 2003-04-14 | 2005-01-06 | Regents Of The University Of California | Combined use of IMPDH inhibitors with toll-like receptor agonists |
-
2004
- 2004-07-30 US US10/903,191 patent/US9259459B2/en not_active Expired - Fee Related
-
2005
- 2005-07-28 CN CN2005800324279A patent/CN101039700B/zh not_active Expired - Fee Related
- 2005-07-28 WO PCT/US2005/027044 patent/WO2006073493A2/en not_active Ceased
- 2005-07-28 AU AU2005323472A patent/AU2005323472B2/en not_active Ceased
- 2005-07-28 EP EP05856893.2A patent/EP1789093B1/en not_active Expired - Lifetime
- 2005-07-28 CA CA002575248A patent/CA2575248A1/en not_active Abandoned
- 2005-07-28 JP JP2007523858A patent/JP4846718B2/ja not_active Expired - Fee Related
-
2009
- 2009-07-02 US US12/496,719 patent/US20090324622A1/en not_active Abandoned
-
2016
- 2016-01-12 US US14/993,265 patent/US20160355593A1/en not_active Abandoned
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| JP2008508313A5 (enExample) | ||
| JP7542870B2 (ja) | 免疫療法のためのナノ粒子組成物及び方法 | |
| Liu et al. | Immunostimulatory CpG oligodeoxynucleotides enhance the immune response to vaccine strategies involving granulocyte-macrophage colony-stimulating factor | |
| Guyre et al. | Increased potency of Fc-receptor-targeted antigens | |
| JP4616838B2 (ja) | ヒト4−1bb(cd137)に対する完全ヒト抗体 | |
| Demangel et al. | Interaction of dendritic cells with mycobacteria: where the action starts | |
| JP2011503014A5 (enExample) | ||
| KR102453188B1 (ko) | 면역요법을 위한 조성물 및 방법 | |
| JP2015083010A5 (enExample) | ||
| JP2013525496A (ja) | ヒトcd8+t細胞の樹状細胞免疫受容体(dcir)媒介クロスプライミング | |
| JP2010518024A5 (enExample) | ||
| WO2012099805A2 (en) | Nanoparticle based immunological stimulation | |
| Jemon et al. | An enhanced heterologous virus-like particle for human papillomavirus type 16 tumour immunotherapy | |
| JP2017508797A (ja) | Tエフェクター細胞の調節性t細胞に対する比を増加するための方法および組成物 | |
| CA2807585A1 (en) | Novel vaccine adjuvants based on targeting adjuvants to antibodies directly to antigen-presenting cells | |
| KR20090127886A (ko) | 수지상 세포 렉틴 유사 산화된 ldl 수용체-1(lox-1)을 통한 사람 항원제시세포의 활성화 | |
| JPH0674210B2 (ja) | 抗原の免疫原性の増強 | |
| CN102172397B (zh) | 树突细胞的体内靶向 | |
| Assudani et al. | In vivo Expansion, Persistence, and Function of Peptide Vaccine–Induced CD8 T Cells Occur Independently of CD4 T Cells | |
| US20050191313A1 (en) | Vaccine and immunotherapy for solid nonlymphoid tumor and related immune dysregulation | |
| JP2023528017A5 (enExample) | ||
| Woo et al. | Co‐administration of carcinoembryonic antigen and HIV TAT fusion protein with CpG‐oligodeoxynucleotide induces potent antitumor immunity | |
| Lee et al. | Human ferritin platform and its optimized structures to enhance anti‐cancer immunity | |
| US20210347906A1 (en) | Fusion proteins for immunotherapy against cancer and infectious diseases | |
| WO2008107641A1 (en) | Liposome preparation |