JP2008508279A - 腎疾患を治療するためのビタミンdの使用 - Google Patents

腎疾患を治療するためのビタミンdの使用 Download PDF

Info

Publication number
JP2008508279A
JP2008508279A JP2007523596A JP2007523596A JP2008508279A JP 2008508279 A JP2008508279 A JP 2008508279A JP 2007523596 A JP2007523596 A JP 2007523596A JP 2007523596 A JP2007523596 A JP 2007523596A JP 2008508279 A JP2008508279 A JP 2008508279A
Authority
JP
Japan
Prior art keywords
pharmaceutical composition
vitamin
composition according
dosage form
paricalcitol
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
JP2007523596A
Other languages
English (en)
Japanese (ja)
Other versions
JP2008508279A5 (OSRAM
Inventor
メルニツク,ジヨエル
テン,チン
ウイリアムズ,ローラ
デルガド−ハーレラ,レテイツイア
チユイ,ピン
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Abbott Laboratories
Original Assignee
Abbott Laboratories
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US10/901,660 external-priority patent/US20050148557A1/en
Application filed by Abbott Laboratories filed Critical Abbott Laboratories
Publication of JP2008508279A publication Critical patent/JP2008508279A/ja
Publication of JP2008508279A5 publication Critical patent/JP2008508279A5/ja
Withdrawn legal-status Critical Current

Links

Images

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/401Proline; Derivatives thereof, e.g. captopril
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/59Compounds containing 9, 10- seco- cyclopenta[a]hydrophenanthrene ring systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/59Compounds containing 9, 10- seco- cyclopenta[a]hydrophenanthrene ring systems
    • A61K31/5929,10-Secoergostane derivatives, e.g. ergocalciferol, i.e. vitamin D2
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/59Compounds containing 9, 10- seco- cyclopenta[a]hydrophenanthrene ring systems
    • A61K31/5939,10-Secocholestane derivatives, e.g. cholecalciferol, i.e. vitamin D3
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00Drugs for disorders of the urinary system
    • A61P13/12Drugs for disorders of the urinary system of the kidneys
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0019Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A61K9/0024Solid, semi-solid or solidifying implants, which are implanted or injected in body tissue
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/70Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7023Transdermal patches and similar drug-containing composite devices, e.g. cataplasms

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Urology & Nephrology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
JP2007523596A 2004-07-28 2005-07-08 腎疾患を治療するためのビタミンdの使用 Withdrawn JP2008508279A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US10/901,660 US20050148557A1 (en) 2003-07-29 2004-07-28 Use of Vitamin Ds to treat kidney disease
US10/974,243 US20050124591A1 (en) 2003-07-29 2004-10-27 Use of vitamin Ds to treat kidney disease
PCT/US2005/024446 WO2006019659A1 (en) 2004-07-28 2005-07-08 Use of vitamin ds to treat kidney disease

Publications (2)

Publication Number Publication Date
JP2008508279A true JP2008508279A (ja) 2008-03-21
JP2008508279A5 JP2008508279A5 (OSRAM) 2008-10-02

Family

ID=34982541

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2007523596A Withdrawn JP2008508279A (ja) 2004-07-28 2005-07-08 腎疾患を治療するためのビタミンdの使用

Country Status (5)

Country Link
US (1) US20050124591A1 (OSRAM)
EP (1) EP1786407A1 (OSRAM)
JP (1) JP2008508279A (OSRAM)
CA (1) CA2575155A1 (OSRAM)
WO (1) WO2006019659A1 (OSRAM)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2015536301A (ja) * 2012-10-09 2015-12-21 レグルス セラピューティクス インコーポレイテッド アルポート症候群の処置方法
JP2016523890A (ja) * 2013-06-27 2016-08-12 ヴィルバク 進行性腎疾患の治療のための組成物

Families Citing this family (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2007001969A1 (en) * 2005-06-27 2007-01-04 The General Hospital Corporation Vitamin d deficiency and dialysis
CA2624897C (en) * 2005-10-12 2017-02-14 Proventiv Therapeutics, Llc Methods and articles for treating 25-hydroxyvitamin d insufficiency and deficiency
SI1993559T1 (sl) 2006-02-03 2017-01-31 Opko Renal, Llc Zdravljenje nezadostnosti in pomanjkanja vitamina D s 25-hidroksivitaminon D2 in 25-hidroksivitaminom D3
PT2679228T (pt) 2006-06-21 2018-04-16 Opko Ireland Global Holdings Ltd Terapia utilizando um agente de repleção de vitamina d e um agente de substituição hormonal de vitamina d
US10716798B2 (en) * 2007-02-21 2020-07-21 The Regents Of The University Of Michigan Compositions and methods for tranquilizing heart muscle
CA2684778C (en) * 2007-04-25 2017-09-05 Cytochroma Inc. Methods and compounds for vitamin d therapy
KR101959952B1 (ko) 2007-04-25 2019-03-19 사이토크로마 인코포레이티드 비타민 d 화합물과 밀랍성 담체를 포함하는 경구 조절성 방출 조성물
CN104257667B (zh) * 2007-04-25 2019-06-04 欧普科Ip 控股Ii 有限公司 治疗维生素d不足和缺乏、继发性甲状旁腺功能亢进症和维生素d-响应疾病的方法和组合物
EP3225243B1 (en) 2007-04-25 2025-09-03 Opko Renal, LLC Method of safely and effectively treating and preventing secondary hyperparathyroidism in chronic kidney disease
US8318708B2 (en) * 2007-11-06 2012-11-27 Salk Institute For Biological Studies Use of vitamin D receptor agonists, ligands, and precursors to treat pancreatic fibrosis
CA2963341A1 (en) * 2007-11-06 2009-05-14 University Of Sydney Use of vitamin d receptor agonists and precursors to treat fibrosis
CN106853250A (zh) 2008-04-02 2017-06-16 赛特克罗公司 用于维生素d缺乏症和相关障碍的方法、组合物、用途和试剂盒
JP5908402B2 (ja) * 2009-08-03 2016-04-26 ウィスコンシン・アルムニ・リサーチ・ファウンデーションWisconsin Alumni Research Foundation 腎疾患の予防方法およびその症状を処置する方法
ES2783980T3 (es) 2010-03-29 2020-09-21 Opko Ireland Global Holdings Ltd Métodos y composiciones para la reducción de niveles de paratiroides
CN103620035B (zh) 2011-04-25 2021-04-23 赛诺菲 用于调节mir-21活性的微rna化合物以及方法
BR112014026639A8 (pt) 2012-04-25 2018-01-16 Regulus Therapeutics Inc compostos , métodos de inibição da atividade de mir-21 , método para diminuir a expressão de colágeno , método para tratar , prevenir ou atrasar o início de uma doença , método de tratamento de um distúrbio fibroproliferativo e usos de um composto.
US9205096B2 (en) 2012-06-29 2015-12-08 Wisconsin Alumni Research Foundation Use of 2-methylene-19-nor-(20S)-1α,25-dihydroxyvitamin D3 to treat secondary hyperparathyroidism
KR101847947B1 (ko) 2013-03-15 2018-05-28 옵코 아이피 홀딩스 Ⅱ 인코포레이티드 안정화되고 변형된 비타민 d 방출 제형
MX2015014701A (es) 2013-04-24 2016-08-08 Salk Inst For Biological Studi Circuito genomico del receptor de vitamina d/smad que regula la compuerta de la respuesta fibrotica.
CN105451818A (zh) 2013-06-05 2016-03-30 萨克生物研究学院 治疗涉及cxcl12活性的疾病的维生素d受体激动剂
US10220047B2 (en) 2014-08-07 2019-03-05 Opko Ireland Global Holdings, Ltd. Adjunctive therapy with 25-hydroxyvitamin D and articles therefor
US9539264B2 (en) 2014-12-30 2017-01-10 Wisconsin Alumni Research Foundation Use of 2-methylene-19-nor-(20S)-1-alpha,25-dihydroxyvitamin D3 to treat secondary hyperparathyroidism in patients previously treated with calcimimetics
US10369161B2 (en) 2014-12-30 2019-08-06 Wisconsin Alumni Research Foundation Use of 2-methylene-19-NOR-(20S)-1-alpha,25-dihydroxyvitamin D3 to treat primary hyperparathyroidism
MY198547A (en) 2016-03-28 2023-09-04 Opko Ireland Global Holdings Ltd Methods of vitamin d treatment
WO2019023149A1 (en) 2017-07-24 2019-01-31 Salk Institute For Biological Studies USE OF BROMODOMAIN-CONTAINING PROTEIN-9 ANTAGONISTS IN ASSOCIATION WITH VITAMIN D RECEPTOR AGONISTS IN THE TREATMENT OF DIABETES
ES2968898T3 (es) * 2019-06-06 2024-05-14 Fundacion Instituto De Investig Sanitaria Fundacion Jimenez Diaz Método in vitro para detectar enfermedad renal

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6747008B1 (en) * 2000-06-19 2004-06-08 University Of Southern California Methods for treating and preventing alopecia
FR2825087B1 (fr) * 2001-05-22 2005-01-14 Galderma Res & Dev Analogues de la vitamine d

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2015536301A (ja) * 2012-10-09 2015-12-21 レグルス セラピューティクス インコーポレイテッド アルポート症候群の処置方法
JP2016523890A (ja) * 2013-06-27 2016-08-12 ヴィルバク 進行性腎疾患の治療のための組成物

Also Published As

Publication number Publication date
CA2575155A1 (en) 2006-02-23
US20050124591A1 (en) 2005-06-09
EP1786407A1 (en) 2007-05-23
WO2006019659A1 (en) 2006-02-23

Similar Documents

Publication Publication Date Title
JP2008508279A (ja) 腎疾患を治療するためのビタミンdの使用
US12171731B2 (en) Methods and compositions for the treatment of steatosis-associated disorders
Cheng et al. Modulation of hypovitaminosis D-induced islet dysfunction and insulin resistance through direct suppression of the pancreatic islet renin–angiotensin system in mice
Lucisano et al. New insights on the role of vitamin D in the progression of renal damage
Petkovich et al. Modified-release oral calcifediol corrects vitamin D insufficiency with minimal CYP24A1 upregulation
US20050148557A1 (en) Use of Vitamin Ds to treat kidney disease
JP6337170B2 (ja) ネコの全身性疾患の予防又は治療の為のアンジオテンシンii受容体アンタゴニスト
Wang et al. Topical calcitriol application promotes diabetic corneal wound healing and reinnervation through inhibiting NLRP3 inflammasome activation
CA2504751C (en) Methods for treating gastroesophageal reflux disease
Xiaowei et al. Comparison of the effects of valsartan plus activated vitamin D versus valsartan alone in IgA nephropathy with moderate proteinuria
US20070093459A1 (en) Use of Vitamin Ds or Vitamin D analogs to treat cardiovascular disease
KR101842295B1 (ko) 관절의 치료를 위한 주사가능한 약학 조성물
TW202339758A (zh) 藉由週期性遏制醛固酮合酶治療高血壓之方法
US20060171983A1 (en) Use of Vitamin D receptor activators or Vitamin D analogs to treat cardiovascular disease
Nakhoul et al. Diabetic nephropathy from RAAS to autophagy: the era for new players
MX2007001136A (es) Uso de vitamina s para tratar enfermedad renal.
US20050192255A1 (en) Use of Vitamin Ds or Vitamin D analogs to treat cardiovascular disease
E Gullo et al. Blockade of renin angiotensin system in heart failure post-myocardial infarction: what is the best therapy?
CN100589806C (zh) 类固醇衍生物在制备治疗血管紧张素ⅱ相关性疾病如心血管性和增生性疾病的药物中的应用
WO2005011660A1 (en) Use of vitamin d to down regulate the renin-angiotensin-aldosterone system
Mendes et al. The role of Paricalcitol in urinary albumin-to-creatinine ratio in patients with type 2 diabetes and chronic kidney disease
MX2007001133A (es) Uso de activadores de receptor de vitamina d o analogos de vitamina d para tratar enfermedades cardiovasculares.
JP2008540448A (ja) 糖尿病性腎症の治療において、スロデキシド及び血圧低下薬を用いた併用療法
WO2025125409A1 (en) Angiotensin ii receptor antagonist for the prevention of systemic diseases in cats
US20170369551A1 (en) METHODS OF TREATING IgA NEPHROPATHY AND HENOCH-SCHONLEIN PURPURA NEPHRITIS USING A B-CELL ACTIVATING FACTOR (BAFF) INHIBITOR

Legal Events

Date Code Title Description
A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A523

Effective date: 20080707

A621 Written request for application examination

Free format text: JAPANESE INTERMEDIATE CODE: A621

Effective date: 20080707

A761 Written withdrawal of application

Free format text: JAPANESE INTERMEDIATE CODE: A761

Effective date: 20110224