JP2008507961A5 - - Google Patents

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Publication number
JP2008507961A5
JP2008507961A5 JP2007522989A JP2007522989A JP2008507961A5 JP 2008507961 A5 JP2008507961 A5 JP 2008507961A5 JP 2007522989 A JP2007522989 A JP 2007522989A JP 2007522989 A JP2007522989 A JP 2007522989A JP 2008507961 A5 JP2008507961 A5 JP 2008507961A5
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JP
Japan
Prior art keywords
cell
cells
tumor
peripheral blood
necrosis factor
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Application number
JP2007522989A
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English (en)
Japanese (ja)
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JP2008507961A (ja
JP5042826B2 (ja
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Priority claimed from EP04017907A external-priority patent/EP1621550A1/en
Application filed filed Critical
Publication of JP2008507961A publication Critical patent/JP2008507961A/ja
Publication of JP2008507961A5 publication Critical patent/JP2008507961A5/ja
Application granted granted Critical
Publication of JP5042826B2 publication Critical patent/JP5042826B2/ja
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

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JP2007522989A 2004-07-29 2005-07-21 腫瘍壊死因子関連アポトーシス誘導リガンド(trail)を産生するように遺伝子操作された腫瘍帰巣細胞 Expired - Fee Related JP5042826B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP04017907A EP1621550A1 (en) 2004-07-29 2004-07-29 Tumor-homing cells engineered to produce tumor necrosis factor-related apoptosis-inducing ligand (TRAIL)
EP04017907.9 2004-07-29
PCT/EP2005/007957 WO2006010558A1 (en) 2004-07-29 2005-07-21 Tumor-homing cells engineered to produce tumor necrosis factor-related apoptosis-inducing ligand (trail)

Publications (3)

Publication Number Publication Date
JP2008507961A JP2008507961A (ja) 2008-03-21
JP2008507961A5 true JP2008507961A5 (cg-RX-API-DMAC10.html) 2008-09-11
JP5042826B2 JP5042826B2 (ja) 2012-10-03

Family

ID=34925971

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2007522989A Expired - Fee Related JP5042826B2 (ja) 2004-07-29 2005-07-21 腫瘍壊死因子関連アポトーシス誘導リガンド(trail)を産生するように遺伝子操作された腫瘍帰巣細胞

Country Status (24)

Country Link
US (1) US20070264231A1 (cg-RX-API-DMAC10.html)
EP (2) EP1621550A1 (cg-RX-API-DMAC10.html)
JP (1) JP5042826B2 (cg-RX-API-DMAC10.html)
KR (1) KR20070047757A (cg-RX-API-DMAC10.html)
CN (1) CN101076540B (cg-RX-API-DMAC10.html)
AT (1) ATE455847T1 (cg-RX-API-DMAC10.html)
AU (1) AU2005266543B2 (cg-RX-API-DMAC10.html)
BR (1) BRPI0513855A (cg-RX-API-DMAC10.html)
CA (1) CA2571426A1 (cg-RX-API-DMAC10.html)
DE (1) DE602005019050D1 (cg-RX-API-DMAC10.html)
DK (1) DK1771468T3 (cg-RX-API-DMAC10.html)
ES (1) ES2340400T3 (cg-RX-API-DMAC10.html)
HR (1) HRP20100227T1 (cg-RX-API-DMAC10.html)
IL (1) IL180233A (cg-RX-API-DMAC10.html)
MX (1) MX2007001152A (cg-RX-API-DMAC10.html)
NO (1) NO20070956L (cg-RX-API-DMAC10.html)
NZ (1) NZ552223A (cg-RX-API-DMAC10.html)
PL (1) PL1771468T3 (cg-RX-API-DMAC10.html)
PT (1) PT1771468E (cg-RX-API-DMAC10.html)
RS (1) RS51381B (cg-RX-API-DMAC10.html)
RU (1) RU2390558C2 (cg-RX-API-DMAC10.html)
SI (1) SI1771468T1 (cg-RX-API-DMAC10.html)
WO (1) WO2006010558A1 (cg-RX-API-DMAC10.html)
ZA (1) ZA200701231B (cg-RX-API-DMAC10.html)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20080199423A1 (en) * 2004-06-18 2008-08-21 Genentech, Inc. Methods of Using Apo2l Receptor Agonists and Ink Cell Activators
DE102006020307A1 (de) * 2006-05-03 2007-11-08 Martin-Luther-Universität Halle-Wittenberg TNF-related apoptosis-including (TRAIL)stabil transgen exprimierende mesenchymale Stammzellen, Verfahren zu ihrer Herstellung und zu ihrer Verwendung
JP5339533B2 (ja) * 2007-05-18 2013-11-13 国立大学法人旭川医科大学 血管内皮前駆細胞の移植による抗がん療法
CN102154213B (zh) * 2011-01-19 2012-07-25 郑骏年 一种运载荷载细胞因子的双调控溶瘤腺病毒的新型cik细胞
KR102053385B1 (ko) * 2012-02-01 2019-12-06 포항공과대학교 산학협력단 12량체 trail 및 hsv-tk 자살유전자를 동시에 발현하는 벡터 및 이를 이용한 항암 줄기세포 치료제
CN103288966B (zh) * 2013-05-17 2015-01-21 华侨大学 一种融合受体及其用于治疗大肠癌的基因药物
RU2552609C1 (ru) * 2013-10-28 2015-06-10 Федеральное государственное бюджетное учреждение науки Институт молекулярной биотехнологии им. В.А. Энгельгардта Российской академии наук (ИМБ РАН) Способ получения системы направленной доставки белковых молекул (онколитических белков) в опухолевые ткани на основе активированных лимфоцитов
ES2841075T3 (es) 2014-10-24 2021-07-07 Calidi Biotherapeutics Inc Enfoque de inmunoterapia de combinación para el tratamiento del cáncer
US10906951B2 (en) 2015-07-29 2021-02-02 Onk Therapeutics Limited Modified natural killer cells and natural killer cell lines having increased cytotoxicity
EP3828266B1 (en) * 2015-07-29 2022-11-23 ONK Therapeutics Limited Modified natural killer cells and natural killer cell lines having increased cytotoxicity
US12692308B2 (en) 2018-06-06 2026-07-28 Stemcell Technologies Canada Inc. Kits, compositions and methods for cell enrichment
US12220465B2 (en) 2018-11-28 2025-02-11 Washington University Compositions and methods for targeted treatment and imaging of cancer or tumors
JP2022526504A (ja) * 2019-03-21 2022-05-25 オーエヌケー セラピューティクス リミテッド 細胞死に対する耐性が増大した改変免疫エフェクター細胞
EP3712257A1 (en) 2019-03-21 2020-09-23 ONK Therapeutics Limited Modified natural killer cells with increased resistance to cell death
WO2021209625A1 (en) 2020-04-17 2021-10-21 Onk Therapeutics Limited High potency natural killer cells

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5879672A (en) * 1994-10-07 1999-03-09 Regeneron Pharmaceuticals, Inc. Tie-2 ligand 1
PT1012259E (pt) * 1997-06-04 2009-11-06 Oxford Biomedica Ltd Vector dirigido a tumor
EP1317288A2 (en) * 2000-09-11 2003-06-11 MUSC Foundation For Research Development Method and composition for treating tumors by selective induction of apoptosis
WO2002066044A2 (en) * 2000-10-24 2002-08-29 Immunex Corporation Method for dendritic cells based immunotherapy of tumors using combination therapy
US7235358B2 (en) * 2001-06-08 2007-06-26 Expression Diagnostics, Inc. Methods and compositions for diagnosing and monitoring transplant rejection
JP4493882B2 (ja) * 2001-06-19 2010-06-30 株式会社カネカ 抗原およびこの抗原を識別するモノクローナル抗体

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