JP2008507529A - 抗サイトカインレセプター抗体を用いる診断のための方法 - Google Patents
抗サイトカインレセプター抗体を用いる診断のための方法 Download PDFInfo
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- 210000000952 spleen Anatomy 0.000 description 1
- 238000010186 staining Methods 0.000 description 1
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- 208000023516 stroke disease Diseases 0.000 description 1
- 238000004809 thin layer chromatography Methods 0.000 description 1
- 210000000115 thoracic cavity Anatomy 0.000 description 1
- 210000001541 thymus gland Anatomy 0.000 description 1
- 239000005495 thyroid hormone Substances 0.000 description 1
- 229940036555 thyroid hormone Drugs 0.000 description 1
- 229960001479 tosylchloramide sodium Drugs 0.000 description 1
- 231100000765 toxin Toxicity 0.000 description 1
- 239000003053 toxin Substances 0.000 description 1
- 108700012359 toxins Proteins 0.000 description 1
- 238000013518 transcription Methods 0.000 description 1
- 230000035897 transcription Effects 0.000 description 1
- 238000001890 transfection Methods 0.000 description 1
- 238000011282 treatment Methods 0.000 description 1
- YNJBWRMUSHSURL-UHFFFAOYSA-N trichloroacetic acid Chemical compound OC(=O)C(Cl)(Cl)Cl YNJBWRMUSHSURL-UHFFFAOYSA-N 0.000 description 1
- RYFMWSXOAZQYPI-UHFFFAOYSA-K trisodium phosphate Chemical compound [Na+].[Na+].[Na+].[O-]P([O-])([O-])=O RYFMWSXOAZQYPI-UHFFFAOYSA-K 0.000 description 1
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- 230000008673 vomiting Effects 0.000 description 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 1
- 230000004584 weight gain Effects 0.000 description 1
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- 208000016261 weight loss Diseases 0.000 description 1
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Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
- A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
- A61K51/04—Organic compounds
- A61K51/08—Peptides, e.g. proteins, carriers being peptides, polyamino acids, proteins
- A61K51/10—Antibodies or immunoglobulins; Fragments thereof, the carrier being an antibody, an immunoglobulin or a fragment thereof, e.g. a camelised human single domain antibody or the Fc fragment of an antibody
- A61K51/1027—Antibodies or immunoglobulins; Fragments thereof, the carrier being an antibody, an immunoglobulin or a fragment thereof, e.g. a camelised human single domain antibody or the Fc fragment of an antibody against receptors, cell-surface antigens or cell-surface determinants
- A61K51/1033—Antibodies or immunoglobulins; Fragments thereof, the carrier being an antibody, an immunoglobulin or a fragment thereof, e.g. a camelised human single domain antibody or the Fc fragment of an antibody against receptors, cell-surface antigens or cell-surface determinants against receptors for cytokines, lymphokines or interferons
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
- A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
- A61K51/04—Organic compounds
- A61K51/08—Peptides, e.g. proteins, carriers being peptides, polyamino acids, proteins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
- A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
- A61K51/04—Organic compounds
- A61K51/08—Peptides, e.g. proteins, carriers being peptides, polyamino acids, proteins
- A61K51/10—Antibodies or immunoglobulins; Fragments thereof, the carrier being an antibody, an immunoglobulin or a fragment thereof, e.g. a camelised human single domain antibody or the Fc fragment of an antibody
- A61K51/1021—Antibodies or immunoglobulins; Fragments thereof, the carrier being an antibody, an immunoglobulin or a fragment thereof, e.g. a camelised human single domain antibody or the Fc fragment of an antibody against cytokines, e.g. growth factors, VEGF, TNF, lymphokines or interferons
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Epidemiology (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Optics & Photonics (AREA)
- Pharmacology & Pharmacy (AREA)
- Physics & Mathematics (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Immunology (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US59040004P | 2004-07-22 | 2004-07-22 | |
| PCT/US2005/025588 WO2006014646A2 (en) | 2004-07-22 | 2005-07-20 | Methods for diagnosis using anti-cytokine receptor antibodies |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2008507529A true JP2008507529A (ja) | 2008-03-13 |
| JP2008507529A5 JP2008507529A5 (https=) | 2008-09-11 |
Family
ID=35787681
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2007522656A Pending JP2008507529A (ja) | 2004-07-22 | 2005-07-20 | 抗サイトカインレセプター抗体を用いる診断のための方法 |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US7727528B2 (https=) |
| EP (1) | EP1781818B1 (https=) |
| JP (1) | JP2008507529A (https=) |
| AU (1) | AU2005269820B2 (https=) |
| CA (1) | CA2574496C (https=) |
| DK (1) | DK1781818T3 (https=) |
| WO (1) | WO2006014646A2 (https=) |
Families Citing this family (28)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB0315656D0 (en) * | 2003-07-03 | 2003-08-13 | Oxonica Ltd | Metal oxide formulations |
| US8062864B2 (en) | 2007-05-21 | 2011-11-22 | Alderbio Holdings Llc | Nucleic acids encoding antibodies to IL-6, and recombinant production of anti-IL-6 antibodies |
| US8404235B2 (en) | 2007-05-21 | 2013-03-26 | Alderbio Holdings Llc | Antagonists of IL-6 to raise albumin and/or lower CRP |
| US8178101B2 (en) | 2007-05-21 | 2012-05-15 | Alderbio Holdings Inc. | Use of anti-IL-6 antibodies having specific binding properties to treat cachexia |
| US7906117B2 (en) | 2007-05-21 | 2011-03-15 | Alderbio Holdings Llc | Antagonists of IL-6 to prevent or treat cachexia, weakness, fatigue, and/or fever |
| US9701747B2 (en) | 2007-05-21 | 2017-07-11 | Alderbio Holdings Llc | Method of improving patient survivability and quality of life by anti-IL-6 antibody administration |
| US20090238825A1 (en) * | 2007-05-21 | 2009-09-24 | Kovacevich Brian R | Novel rabbit antibody humanization methods and humanized rabbit antibodies |
| HUE032563T2 (en) | 2007-05-21 | 2017-09-28 | Alderbio Holdings Llc | Antibodies to IL-6 and their use |
| US8252286B2 (en) | 2007-05-21 | 2012-08-28 | Alderbio Holdings Llc | Antagonists of IL-6 to prevent or treat thrombosis |
| KR20170036814A (ko) * | 2007-05-21 | 2017-04-03 | 앨더바이오 홀딩스 엘엘씨 | 신규한 래빗 항체 인간화 방법 및 인간화된 래빗 항체 |
| US8058204B2 (en) * | 2008-10-24 | 2011-11-15 | GM Global Technology Operations LLC | Method for generating a shell of noble metal overlaid on a core of non-noble metal, and catalysts made thereby |
| US8323649B2 (en) | 2008-11-25 | 2012-12-04 | Alderbio Holdings Llc | Antibodies to IL-6 and use thereof |
| US9452227B2 (en) | 2008-11-25 | 2016-09-27 | Alderbio Holdings Llc | Methods of treating or diagnosing conditions associated with elevated IL-6 using anti-IL-6 antibodies or fragments |
| US8992920B2 (en) | 2008-11-25 | 2015-03-31 | Alderbio Holdings Llc | Anti-IL-6 antibodies for the treatment of arthritis |
| US8420089B2 (en) | 2008-11-25 | 2013-04-16 | Alderbio Holdings Llc | Antagonists of IL-6 to raise albumin and/or lower CRP |
| US8337847B2 (en) | 2008-11-25 | 2012-12-25 | Alderbio Holdings Llc | Methods of treating anemia using anti-IL-6 antibodies |
| US9212223B2 (en) | 2008-11-25 | 2015-12-15 | Alderbio Holdings Llc | Antagonists of IL-6 to prevent or treat thrombosis |
| ES2706403T3 (es) | 2008-12-10 | 2019-03-28 | Joslin Diabetes Center Inc | Métodos para diagnosticar y predecir una enfermedad renal |
| US9775921B2 (en) | 2009-11-24 | 2017-10-03 | Alderbio Holdings Llc | Subcutaneously administrable composition containing anti-IL-6 antibody |
| WO2011066374A2 (en) | 2009-11-24 | 2011-06-03 | Alder Biopharmaceuticals, Inc. | Antagonists of il-6 to prevent or treat cachexia, weakness, fatigue, and/or fever |
| US9304134B2 (en) | 2010-11-23 | 2016-04-05 | Alderbio Holdings Llc | Anti-IL-6 antibodies for the treatment of anemia |
| US20170038382A1 (en) * | 2014-01-24 | 2017-02-09 | Ntercept, Llc | Methods and compositions for immune dis-inhibition |
| MX2017003903A (es) | 2014-10-03 | 2017-09-15 | Ntercept Llc | Composiciones y metodos para inhibir la actividad biologica de biomoleculas solubles. |
| EA201890391A1 (ru) | 2015-07-29 | 2018-08-31 | НАНОТИКС, ЭлЭлСи | Модульные композиции для утилизации растворимых биомолекул и связанные с этим способы |
| WO2017083525A1 (en) * | 2015-11-11 | 2017-05-18 | Opi Vi- Ip Holdco Llc | Composition and methods for anti-tnfr2 antibodies |
| US10858422B2 (en) | 2016-05-31 | 2020-12-08 | Abcentra, Llc | Methods for treating systemic lupus erythematosus with an anti-apolipoprotein B antibody |
| EP3463416A1 (en) | 2016-05-31 | 2019-04-10 | CardioVax, LLC | Methods for diagnosing and treating systemic lupus erythematosus |
| US11065345B2 (en) | 2017-01-04 | 2021-07-20 | Nanotics, Llc | Methods for assembling scavenging particles |
Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2002516157A (ja) * | 1998-05-22 | 2002-06-04 | エム． リグドン レンツ， | 癌の治療のための方法および組成物 |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
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| US5965132A (en) | 1992-03-05 | 1999-10-12 | Board Of Regents, The University Of Texas System | Methods and compositions for targeting the vasculature of solid tumors |
| US6096289A (en) | 1992-05-06 | 2000-08-01 | Immunomedics, Inc. | Intraoperative, intravascular, and endoscopic tumor and lesion detection, biopsy and therapy |
| JPH0630788A (ja) * | 1992-07-16 | 1994-02-08 | Otsuka Pharmaceut Co Ltd | ヒトインターロイキン−１に対する組換え抗体 |
| US20030138426A1 (en) * | 1997-10-21 | 2003-07-24 | Human Genome Sciences, Inc. | Human tumor necrosis factor receptor-like proteins TR11, TR11SV1, and TR11SV2 |
| US20020039764A1 (en) * | 1999-03-12 | 2002-04-04 | Rosen Craig A. | Nucleic, acids, proteins, and antibodies |
| CN1981868A (zh) * | 2000-03-31 | 2007-06-20 | 拜奥根Idec公司 | 抗细胞因子抗体或拮抗剂与抗－cd20在b细胞淋巴瘤治疗中的联合应用 |
| US7358041B2 (en) * | 2001-11-30 | 2008-04-15 | Short Mary K | Antibodies to magmas and uses thereof |
| US20040072237A1 (en) * | 2001-12-26 | 2004-04-15 | Barry Schweitzer | Use of cytokines secreted by dendritic cells |
| WO2005107802A2 (en) * | 2004-04-30 | 2005-11-17 | Biopheresis Technologies, Llc | Method and system to remove soluble tnfr1, tnfr2, and il2 in patients |
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2005
- 2005-07-20 DK DK05775665.2T patent/DK1781818T3/en active
- 2005-07-20 EP EP05775665.2A patent/EP1781818B1/en not_active Expired - Lifetime
- 2005-07-20 US US11/185,335 patent/US7727528B2/en active Active
- 2005-07-20 AU AU2005269820A patent/AU2005269820B2/en not_active Ceased
- 2005-07-20 CA CA2574496A patent/CA2574496C/en not_active Expired - Fee Related
- 2005-07-20 WO PCT/US2005/025588 patent/WO2006014646A2/en not_active Ceased
- 2005-07-20 JP JP2007522656A patent/JP2008507529A/ja active Pending
Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2002516157A (ja) * | 1998-05-22 | 2002-06-04 | エム． リグドン レンツ， | 癌の治療のための方法および組成物 |
Also Published As
| Publication number | Publication date |
|---|---|
| US7727528B2 (en) | 2010-06-01 |
| DK1781818T3 (en) | 2017-10-16 |
| EP1781818B1 (en) | 2017-09-06 |
| AU2005269820B2 (en) | 2009-03-26 |
| US20060039857A1 (en) | 2006-02-23 |
| EP1781818A4 (en) | 2008-12-03 |
| AU2005269820A1 (en) | 2006-02-09 |
| CA2574496C (en) | 2014-04-22 |
| WO2006014646A2 (en) | 2006-02-09 |
| WO2006014646A3 (en) | 2006-05-04 |
| CA2574496A1 (en) | 2006-02-09 |
| EP1781818A2 (en) | 2007-05-09 |
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