JP2008506416A - 遺伝子組み換えされた細胞が合胞体の機能を変える効果を監視するための分析システム - Google Patents

遺伝子組み換えされた細胞が合胞体の機能を変える効果を監視するための分析システム Download PDF

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JP2008506416A
JP2008506416A JP2007522698A JP2007522698A JP2008506416A JP 2008506416 A JP2008506416 A JP 2008506416A JP 2007522698 A JP2007522698 A JP 2007522698A JP 2007522698 A JP2007522698 A JP 2007522698A JP 2008506416 A JP2008506416 A JP 2008506416A
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syncytial
cell
rhythm
cells
contacting
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JP2008506416A5 (https=
Inventor
リチャード・ビー・ロビンソン
マイケル・アール・ローゼン
アイラ・エス・コーエン
ピーター・アール・ブリンク
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Columbia University in the City of New York
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Columbia University in the City of New York
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    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
    • G01N33/5008—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
    • G01N33/5044—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics involving specific cell types
    • G01N33/5061—Muscle cells

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Cell Biology (AREA)
  • Biomedical Technology (AREA)
  • Immunology (AREA)
  • Hematology (AREA)
  • Chemical & Material Sciences (AREA)
  • Urology & Nephrology (AREA)
  • Molecular Biology (AREA)
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  • Physics & Mathematics (AREA)
  • Biotechnology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Microbiology (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
JP2007522698A 2004-07-19 2005-07-19 遺伝子組み換えされた細胞が合胞体の機能を変える効果を監視するための分析システム Withdrawn JP2008506416A (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US58941604P 2004-07-19 2004-07-19
PCT/US2005/025735 WO2006020322A2 (en) 2004-07-19 2005-07-19 Assay system for monitoring the effects of genetically engineered cells to alter function of a syncytium

Publications (2)

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JP2008506416A true JP2008506416A (ja) 2008-03-06
JP2008506416A5 JP2008506416A5 (https=) 2008-09-04

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JP2007522698A Withdrawn JP2008506416A (ja) 2004-07-19 2005-07-19 遺伝子組み換えされた細胞が合胞体の機能を変える効果を監視するための分析システム

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US (1) US8192929B2 (https=)
EP (1) EP1781371A4 (https=)
JP (1) JP2008506416A (https=)
WO (1) WO2006020322A2 (https=)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2020501134A (ja) * 2016-11-25 2020-01-16 ウニベルジテート ロストック 心伝導を決定するための方法、デバイス及びキット

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2009120082A2 (en) * 2008-03-27 2009-10-01 Academisch Medisch Centrum Bij De Universiteit Van Amsterdam Means and methods for influencing electrical activity of cells
US20110144028A1 (en) * 2009-12-11 2011-06-16 Vinod Sharma Modulating cellular electrophysiology
SG11201807223UA (en) * 2016-03-23 2018-09-27 Univ Columbia CANCER TREATMENT BASED ON DELIVERY OF OLIGOES VIA GAP JUNCTIONS FROM HUMAN MESENCHYMAL STEM CELLS (hMSC)

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2296704C (en) * 1997-07-14 2010-10-19 Osiris Therapeutics, Inc. Cardiac muscle regeneration using mesenchymal stem cells
US6776987B1 (en) * 1998-01-13 2004-08-17 Massachusetts Institute Of Technology Enhancement of cardiac chronotropy
US6410236B1 (en) * 1999-09-01 2002-06-25 The Regents Of The University Of Michigan Correcting diastolic dysfunction in heart failure
EP1324780A4 (en) * 2000-09-06 2005-06-22 Univ Johns Hopkins METHODS OF TREATING CARDIAC ARRHYTHMIA
EP1379869A4 (en) * 2001-03-15 2004-08-11 Xiao Yong Fu METHOD FOR THERAPEUTICALLY TREATING A CLINICALLY DETECTED CARDIOPATHOLOGICAL FORM IN A MAMMAL
WO2002098287A2 (en) * 2001-06-06 2002-12-12 The Trustees Of Columbia University In The City Of New York A high throughput biological heart rate monitor that is molecularly determined
US20030082153A1 (en) * 2001-10-22 2003-05-01 The Government Of The United States Of America Stem cells that transform to beating cardiomyocytes
US7794702B2 (en) * 2003-01-15 2010-09-14 The Trustees Of Columbia University In The City Of New York Mesenchymal stem cells as a vehicle for ion channel transfer in syncytial structures
US8859273B2 (en) * 2003-12-24 2014-10-14 Medtronic, Inc. Methods of using HCN genes to treat cardiac arrhythmias

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2020501134A (ja) * 2016-11-25 2020-01-16 ウニベルジテート ロストック 心伝導を決定するための方法、デバイス及びキット

Also Published As

Publication number Publication date
EP1781371A2 (en) 2007-05-09
EP1781371A4 (en) 2007-12-19
US20100068699A1 (en) 2010-03-18
US20120028241A2 (en) 2012-02-02
US8192929B2 (en) 2012-06-05
WO2006020322A3 (en) 2006-07-27
WO2006020322A2 (en) 2006-02-23

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