JP2008504255A - 結晶塩酸バラシクロビル中の残留アルコールを低減する方法 - Google Patents

結晶塩酸バラシクロビル中の残留アルコールを低減する方法 Download PDF

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Publication number
JP2008504255A
JP2008504255A JP2007518020A JP2007518020A JP2008504255A JP 2008504255 A JP2008504255 A JP 2008504255A JP 2007518020 A JP2007518020 A JP 2007518020A JP 2007518020 A JP2007518020 A JP 2007518020A JP 2008504255 A JP2008504255 A JP 2008504255A
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JP
Japan
Prior art keywords
valaciclovir hydrochloride
storage
formylvalacyclovir
hydrochloride
valaciclovir
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2007518020A
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English (en)
Japanese (ja)
Inventor
ドリツキー，ベンジオン
リフシッツ，イゴア
Original Assignee
テバ ファーマシューティカル インダストリーズ リミティド
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
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Application filed by テバ ファーマシューティカル インダストリーズ リミティド filed Critical テバ ファーマシューティカル インダストリーズ リミティド
Publication of JP2008504255A publication Critical patent/JP2008504255A/ja
Pending legal-status Critical Current

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D473/00—Heterocyclic compounds containing purine ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/20—Antivirals for DNA viruses
    • A61P31/22—Antivirals for DNA viruses for herpes viruses
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D473/00—Heterocyclic compounds containing purine ring systems
    • C07D473/02—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6
    • C07D473/18—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 one oxygen and one nitrogen atom, e.g. guanine

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Virology (AREA)
  • Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Molecular Biology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
JP2007518020A 2004-06-30 2004-06-30 結晶塩酸バラシクロビル中の残留アルコールを低減する方法 Pending JP2008504255A (ja)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/US2004/020903 WO2006011874A1 (fr) 2004-06-30 2004-06-30 Procédé pour réduire les alcools résiduels dans l'hydrochlorure de valacyclovir cristallin

Publications (1)

Publication Number Publication Date
JP2008504255A true JP2008504255A (ja) 2008-02-14

Family

ID=34958221

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2007518020A Pending JP2008504255A (ja) 2004-06-30 2004-06-30 結晶塩酸バラシクロビル中の残留アルコールを低減する方法

Country Status (6)

Country Link
EP (1) EP1761535A1 (fr)
JP (1) JP2008504255A (fr)
CN (1) CN1976933A (fr)
CA (1) CA2572268A1 (fr)
IL (1) IL180351A0 (fr)
WO (1) WO2006011874A1 (fr)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2009049648A2 (fr) * 2007-10-17 2009-04-23 Pharmathen S.A. Composition pharmaceutique améliorée contenant un agent antiviral et procédé de préparation de celle-ci

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH11503718A (ja) * 1995-01-20 1999-03-30 ザ、ウェルカム、ファンデーション、リミテッド グアニン誘導体
WO2004035583A1 (fr) * 2002-10-16 2004-04-29 Teva Pharmaceutical Industries Ltd. Procede pour reduire la quantite d'alcools residuels dans de l'hydrochlorure de valacyclovir cristallin
JP2005508993A (ja) * 2001-11-14 2005-04-07 テバ ファーマシューティカル インダストリーズ リミティド バラシクロビルの合成及び精製
JP2005526694A (ja) * 2001-09-07 2005-09-08 テバ ファーマシューティカル インダストリーズ リミティド バラシクロビル塩酸塩の結晶型

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR100871621B1 (ko) * 2003-06-02 2008-12-02 테바 파마슈티컬 인더스트리즈 리미티드 발라시클로비르 히드로클로라이드의 신규한 결정질 형태

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH11503718A (ja) * 1995-01-20 1999-03-30 ザ、ウェルカム、ファンデーション、リミテッド グアニン誘導体
JP2005526694A (ja) * 2001-09-07 2005-09-08 テバ ファーマシューティカル インダストリーズ リミティド バラシクロビル塩酸塩の結晶型
JP2005508993A (ja) * 2001-11-14 2005-04-07 テバ ファーマシューティカル インダストリーズ リミティド バラシクロビルの合成及び精製
WO2004035583A1 (fr) * 2002-10-16 2004-04-29 Teva Pharmaceutical Industries Ltd. Procede pour reduire la quantite d'alcools residuels dans de l'hydrochlorure de valacyclovir cristallin

Also Published As

Publication number Publication date
IL180351A0 (en) 2007-06-03
WO2006011874A1 (fr) 2006-02-02
EP1761535A1 (fr) 2007-03-14
CA2572268A1 (fr) 2006-02-02
CN1976933A (zh) 2007-06-06

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