JP2008500363A5 - - Google Patents
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- Publication number
- JP2008500363A5 JP2008500363A5 JP2007515318A JP2007515318A JP2008500363A5 JP 2008500363 A5 JP2008500363 A5 JP 2008500363A5 JP 2007515318 A JP2007515318 A JP 2007515318A JP 2007515318 A JP2007515318 A JP 2007515318A JP 2008500363 A5 JP2008500363 A5 JP 2008500363A5
- Authority
- JP
- Japan
- Prior art keywords
- compound
- pharmaceutical composition
- alkyl
- alkylaryl
- arylalkyl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 150000001875 compounds Chemical class 0.000 claims description 14
- 125000000217 alkyl group Chemical group 0.000 claims description 9
- 125000003342 alkenyl group Chemical group 0.000 claims description 8
- 125000002877 alkyl aryl group Chemical group 0.000 claims description 8
- 125000003710 aryl alkyl group Chemical group 0.000 claims description 8
- 125000003118 aryl group Chemical group 0.000 claims description 8
- 125000000753 cycloalkyl group Chemical group 0.000 claims description 8
- 125000004400 (C1-C12) alkyl group Chemical group 0.000 claims description 5
- 125000005843 halogen group Chemical group 0.000 claims description 4
- 125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 claims description 3
- 239000008194 pharmaceutical composition Substances 0.000 claims 9
- 230000002401 inhibitory effect Effects 0.000 claims 3
- 201000011510 cancer Diseases 0.000 claims 2
- 230000000694 effects Effects 0.000 claims 2
- 239000008024 pharmaceutical diluent Substances 0.000 claims 2
- 125000004169 (C1-C6) alkyl group Chemical group 0.000 claims 1
- 101700074018 CPT1A Proteins 0.000 claims 1
- 102100008329 FASN Human genes 0.000 claims 1
- 101710008102 FASN Proteins 0.000 claims 1
- 102100015978 NPY Human genes 0.000 claims 1
- 108020001430 NPY Proteins 0.000 claims 1
- 230000015572 biosynthetic process Effects 0.000 claims 1
- 230000001939 inductive effect Effects 0.000 claims 1
- 230000000813 microbial Effects 0.000 claims 1
- 230000004936 stimulating Effects 0.000 claims 1
- 238000003786 synthesis reaction Methods 0.000 claims 1
- 230000002194 synthesizing Effects 0.000 claims 1
- 230000004580 weight loss Effects 0.000 claims 1
- 0 CC(C)(C1=*(C2)C2C1(CC=*C)S1)C1=O Chemical compound CC(C)(C1=*(C2)C2C1(CC=*C)S1)C1=O 0.000 description 3
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US57463904P | 2004-05-26 | 2004-05-26 | |
| PCT/US2005/018443 WO2005117590A2 (en) | 2004-05-26 | 2005-05-25 | Novel compounds, pharmaceutical compositions containing same, and methods of use for same |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2008500363A JP2008500363A (ja) | 2008-01-10 |
| JP2008500363A5 true JP2008500363A5 (US20080131398A1-20080605-C00009.png) | 2008-07-17 |
Family
ID=35463277
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2007515318A Pending JP2008500363A (ja) | 2004-05-26 | 2005-05-25 | 新規化合物、該化合物を含む医薬組成物、および該化合物の使用方法 |
Country Status (13)
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2007014248A2 (en) * | 2005-07-26 | 2007-02-01 | Johns Hopkins University | Method of reducing food intake |
| EP2946778A1 (en) * | 2006-09-22 | 2015-11-25 | Merck Sharp & Dohme Corp. | Method of treatment using fatty acid synthesis inhibitors |
| US8912177B2 (en) * | 2007-10-05 | 2014-12-16 | Genzyme Corporation | Method of treating polycystic kidney diseases with ceramide derivatives |
| US8729239B2 (en) | 2009-04-09 | 2014-05-20 | Nuclea Biotechnologies, Inc. | Antibodies against fatty acid synthase |
| CA2884355C (en) * | 2012-09-07 | 2022-05-17 | Janssen Pharmaceutica Nv | Imidazolin-5-one derivative useful as fasn inhobitors for the treatment of cancer |
| CA2968288A1 (en) | 2014-11-20 | 2016-05-26 | Vib Vzw | Means and methods for treatment of early-onset parkinson's disease |
| CN115023139A (zh) | 2020-01-23 | 2022-09-06 | 巴斯夫欧洲公司 | 含有醚硫酸盐的ppo配制剂 |
| US20230397609A1 (en) | 2020-10-27 | 2023-12-14 | Basf Se | Pesticide microemulsion compositions |
| AR124823A1 (es) | 2021-02-05 | 2023-05-10 | Basf Se | Composiciones herbicidas líquidas |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE3427847A1 (de) * | 1983-12-09 | 1985-06-13 | Bayer Ag, 5090 Leverkusen | Thiolan-2,4-dion-3-carboxamide |
| US5759837A (en) * | 1989-01-17 | 1998-06-02 | John Hopkins University | Chemotherapy for cancer by inhibiting the fatty acid biosynthetic pathway |
| US5614551A (en) * | 1994-01-24 | 1997-03-25 | The Johns Hopkins University | Inhibitors of fatty acid synthesis as antimicrobial agents |
| US5981575A (en) * | 1996-11-15 | 1999-11-09 | Johns Hopkins University, The | Inhibition of fatty acid synthase as a means to reduce adipocyte mass |
| BR0307421A (pt) * | 2002-02-08 | 2004-12-28 | Johns Kophkins University Scho | Estimulação do cpt-1 como um freio para reduzir peso |
| CA2491802C (en) * | 2002-07-09 | 2012-04-10 | Fasgen, Inc. | Novel compounds, pharmaceutical compositions containing same, and methods of use for same |
-
2005
- 2005-05-25 RU RU2006146051/04A patent/RU2006146051A/ru not_active Application Discontinuation
- 2005-05-25 CA CA002568639A patent/CA2568639A1/en not_active Abandoned
- 2005-05-25 JP JP2007515318A patent/JP2008500363A/ja active Pending
- 2005-05-25 US US11/597,538 patent/US20090005435A1/en not_active Abandoned
- 2005-05-25 MX MXPA06013687A patent/MXPA06013687A/es not_active Application Discontinuation
- 2005-05-25 ZA ZA200700024A patent/ZA200700024B/en unknown
- 2005-05-25 EP EP05754100A patent/EP1758577A4/en not_active Withdrawn
- 2005-05-25 AU AU2005249437A patent/AU2005249437A1/en not_active Abandoned
- 2005-05-25 BR BRPI0510397-5A patent/BRPI0510397A/pt not_active IP Right Cessation
- 2005-05-25 CN CNA2005800233119A patent/CN101022792A/zh active Pending
- 2005-05-25 WO PCT/US2005/018443 patent/WO2005117590A2/en active Application Filing
- 2005-05-25 KR KR1020067026941A patent/KR20070095754A/ko not_active Application Discontinuation
-
2006
- 2006-11-23 IL IL179530A patent/IL179530A0/en unknown
