JP2008500317A - 抗菌剤としての３−’４−｛６−置換アルカノイル）ピリジン−３−イル｝−３−フェニル−５−（１ｈ−１，２，３−トリアゾール−１−イルメチル）−１，３−オキサゾリジン−２−オン - Google Patents
抗菌剤としての３−’４−｛６−置換アルカノイル）ピリジン−３−イル｝−３−フェニル−５−（１ｈ−１，２，３−トリアゾール−１−イルメチル）−１，３−オキサゾリジン−２−オン Download PDFInfo
- Publication number
- JP2008500317A JP2008500317A JP2007514087A JP2007514087A JP2008500317A JP 2008500317 A JP2008500317 A JP 2008500317A JP 2007514087 A JP2007514087 A JP 2007514087A JP 2007514087 A JP2007514087 A JP 2007514087A JP 2008500317 A JP2008500317 A JP 2008500317A
- Authority
- JP
- Japan
- Prior art keywords
- compound
- formula
- mmol
- alkyl
- pharmaceutically acceptable
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 0 CC(C(N(C)N(CC(C*)O1)C1=O)=CC=C)=O Chemical compound CC(C(N(C)N(CC(C*)O1)C1=O)=CC=C)=O 0.000 description 5
- FHBUSSSBPJTBKJ-UHFFFAOYSA-N CC(C)(C)OC(N1CCC(CC(c(nc2)ccc2Br)=O)CC1)=O Chemical compound CC(C)(C)OC(N1CCC(CC(c(nc2)ccc2Br)=O)CC1)=O FHBUSSSBPJTBKJ-UHFFFAOYSA-N 0.000 description 1
- OYTZWPYVHBHOPU-SFHVURJKSA-N CCc1ncc[n]1CC(c(cc1)ncc1-c(ccc(N(C[C@H](C[n]1nncc1)O1)C1=O)c1)c1F)=O Chemical compound CCc1ncc[n]1CC(c(cc1)ncc1-c(ccc(N(C[C@H](C[n]1nncc1)O1)C1=O)c1)c1F)=O OYTZWPYVHBHOPU-SFHVURJKSA-N 0.000 description 1
- MYFGDWAVZIOCKM-MRVPVSSYSA-N CS(OC[C@@H](CN1c(cc2)cc(F)c2I)OC1=O)(=O)=O Chemical compound CS(OC[C@@H](CN1c(cc2)cc(F)c2I)OC1=O)(=O)=O MYFGDWAVZIOCKM-MRVPVSSYSA-N 0.000 description 1
- PVPDCNGXAFKAOT-UHFFFAOYSA-N O=C(CBr)c(nc1)ccc1Br Chemical compound O=C(CBr)c(nc1)ccc1Br PVPDCNGXAFKAOT-UHFFFAOYSA-N 0.000 description 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB0411593A GB0411593D0 (en) | 2004-05-25 | 2004-05-25 | Chemical compounds |
| GB0500054A GB0500054D0 (en) | 2005-01-05 | 2005-01-05 | Chemical compounds |
| PCT/GB2005/002051 WO2005116022A1 (en) | 2004-05-25 | 2005-05-24 | 3- `4- {6-substituted alkanoyl) pyridin-3-yl} -3-phenyl! -5- (1h-1, 2, 3-triazol-1-ylmethyl) -1, 3-oxazolidin-2-ones as antibacterial agents |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2008500317A true JP2008500317A (ja) | 2008-01-10 |
| JP2008500317A5 JP2008500317A5 (enExample) | 2008-06-26 |
Family
ID=34968778
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2007514087A Pending JP2008500317A (ja) | 2004-05-25 | 2005-05-24 | 抗菌剤としての３−’４−｛６−置換アルカノイル）ピリジン−３−イル｝−３−フェニル−５−（１ｈ−１，２，３−トリアゾール−１−イルメチル）−１，３−オキサゾリジン−２−オン |
Country Status (10)
| Country | Link |
|---|---|
| US (1) | US20080021012A1 (enExample) |
| EP (1) | EP1753754A1 (enExample) |
| JP (1) | JP2008500317A (enExample) |
| AU (1) | AU2005247668A1 (enExample) |
| BR (1) | BRPI0511526A (enExample) |
| CA (1) | CA2566963A1 (enExample) |
| IL (1) | IL179349A0 (enExample) |
| MX (1) | MXPA06013537A (enExample) |
| NO (1) | NO20065889L (enExample) |
| WO (1) | WO2005116022A1 (enExample) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR100854211B1 (ko) | 2003-12-18 | 2008-08-26 | 동아제약주식회사 | 신규한 옥사졸리디논 유도체, 그의 제조방법 및 이를유효성분으로 하는 항생제용 약학 조성물 |
| EP2346858B1 (en) * | 2008-10-10 | 2019-08-07 | Merck Sharp & Dohme Corp. | Methods for preparing oxazolidinones and compositions containing them |
| UA114068C2 (xx) | 2009-02-03 | 2017-04-25 | Кристалічні частинки (r)-3-(4-(2-(2-метилтетразол-5-іл)піридин-5-іл)-3-фторфеніл)-5-гідроксиметилоксазолідин-2-ондиводеньфосфату | |
| US8580767B2 (en) * | 2009-05-28 | 2013-11-12 | Trius Therapeutics, Inc. | Oxazolidinone containing dimer compounds, compositions and methods to make and use |
| KR101561964B1 (ko) | 2013-11-15 | 2015-10-20 | 한국과학기술연구원 | 옥사졸리디논 화합물 및 이를 포함하는 c형 간염 예방 또는 치료용 약학 조성물 |
| JP6864379B2 (ja) | 2016-03-31 | 2021-04-28 | オンターナル セラピューティック インコーポレイテッドＯｎｃｔｅｒｎａｌ Ｔｈｅｒａｐｅｕｔｉｃｓ， Ｉｎｃ． | インドール類似体及びその使用 |
| US11555033B2 (en) | 2020-06-18 | 2023-01-17 | Akagera Medicines, Inc. | Oxazolidinone compounds, liposome compositions comprising oxazolidinone compounds and method of use thereof |
Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2003072575A1 (en) * | 2002-02-28 | 2003-09-04 | Astrazeneca Ab | 3-cyclyl-5-(nitrogen-containing 5-membered ring) methyl-oxazolidinone derivatives and their use as antibacterial agents |
| JP2003531211A (ja) * | 2000-04-25 | 2003-10-21 | アストラゼネカ アクチボラグ | 抗生物質活性を持つオキサジリジノン誘導体 |
| JP2003535860A (ja) * | 2000-06-05 | 2003-12-02 | ドン・ア・ファーム・カンパニー・リミテッド | 新規なオキサゾリジノン誘導体及びその製造方法 |
-
2005
- 2005-05-24 BR BRPI0511526-4A patent/BRPI0511526A/pt not_active Application Discontinuation
- 2005-05-24 JP JP2007514087A patent/JP2008500317A/ja active Pending
- 2005-05-24 US US11/569,408 patent/US20080021012A1/en not_active Abandoned
- 2005-05-24 CA CA002566963A patent/CA2566963A1/en not_active Abandoned
- 2005-05-24 MX MXPA06013537A patent/MXPA06013537A/es not_active Application Discontinuation
- 2005-05-24 EP EP05746537A patent/EP1753754A1/en not_active Withdrawn
- 2005-05-24 AU AU2005247668A patent/AU2005247668A1/en not_active Abandoned
- 2005-05-24 WO PCT/GB2005/002051 patent/WO2005116022A1/en not_active Ceased
-
2006
- 2006-11-16 IL IL179349A patent/IL179349A0/en unknown
- 2006-12-19 NO NO20065889A patent/NO20065889L/no not_active Application Discontinuation
Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2003531211A (ja) * | 2000-04-25 | 2003-10-21 | アストラゼネカ アクチボラグ | 抗生物質活性を持つオキサジリジノン誘導体 |
| JP2003535860A (ja) * | 2000-06-05 | 2003-12-02 | ドン・ア・ファーム・カンパニー・リミテッド | 新規なオキサゾリジノン誘導体及びその製造方法 |
| WO2003072575A1 (en) * | 2002-02-28 | 2003-09-04 | Astrazeneca Ab | 3-cyclyl-5-(nitrogen-containing 5-membered ring) methyl-oxazolidinone derivatives and their use as antibacterial agents |
Also Published As
| Publication number | Publication date |
|---|---|
| NO20065889L (no) | 2007-02-20 |
| MXPA06013537A (es) | 2007-01-26 |
| BRPI0511526A (pt) | 2007-12-26 |
| IL179349A0 (en) | 2007-03-08 |
| WO2005116022A1 (en) | 2005-12-08 |
| US20080021012A1 (en) | 2008-01-24 |
| AU2005247668A1 (en) | 2005-12-08 |
| EP1753754A1 (en) | 2007-02-21 |
| CA2566963A1 (en) | 2005-12-08 |
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