JP2008285464A5 - - Google Patents

Download PDF

Info

Publication number
JP2008285464A5
JP2008285464A5 JP2007175769A JP2007175769A JP2008285464A5 JP 2008285464 A5 JP2008285464 A5 JP 2008285464A5 JP 2007175769 A JP2007175769 A JP 2007175769A JP 2007175769 A JP2007175769 A JP 2007175769A JP 2008285464 A5 JP2008285464 A5 JP 2008285464A5
Authority
JP
Japan
Prior art keywords
group
chlorophenyl
alkyl
carbamoyl
substituted
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP2007175769A
Other languages
English (en)
Japanese (ja)
Other versions
JP2008285464A (ja
JP4846665B2 (ja
Filing date
Publication date
Application filed filed Critical
Priority to JP2007175769A priority Critical patent/JP4846665B2/ja
Priority claimed from JP2007175769A external-priority patent/JP4846665B2/ja
Publication of JP2008285464A publication Critical patent/JP2008285464A/ja
Publication of JP2008285464A5 publication Critical patent/JP2008285464A5/ja
Application granted granted Critical
Publication of JP4846665B2 publication Critical patent/JP4846665B2/ja
Expired - Fee Related legal-status Critical Current
Anticipated expiration legal-status Critical

Links

JP2007175769A 2006-07-05 2007-07-04 ピラゾロ［１，５−ａ］ピリミジン化合物 Expired - Fee Related JP4846665B2 (ja)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP2007175769A JP4846665B2 (ja) 2006-07-05 2007-07-04 ピラゾロ［１，５−ａ］ピリミジン化合物

Applications Claiming Priority (9)

Application Number Priority Date Filing Date Title
JP2006185036 2006-07-05
JP2006185036 2006-07-05
JP2007009706 2007-01-19
JP2007009706 2007-01-19
JP2007059332 2007-03-09
JP2007059332 2007-03-09
JP2007111340 2007-04-20
JP2007111340 2007-04-20
JP2007175769A JP4846665B2 (ja) 2006-07-05 2007-07-04 ピラゾロ［１，５−ａ］ピリミジン化合物

Publications (3)

Publication Number Publication Date
JP2008285464A JP2008285464A (ja) 2008-11-27
JP2008285464A5 true JP2008285464A5 (enExample) 2009-04-09
JP4846665B2 JP4846665B2 (ja) 2011-12-28

Family

ID=40145540

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2007175769A Expired - Fee Related JP4846665B2 (ja) 2006-07-05 2007-07-04 ピラゾロ［１，５−ａ］ピリミジン化合物

Country Status (2)

Country Link
JP (1) JP4846665B2 (enExample)
TW (2) TW201345908A (enExample)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
UY30090A1 (es) * 2006-01-16 2007-08-31 Syngenta Participations Ag Insecticidas novedosos
SI2350075T1 (sl) 2008-09-22 2014-06-30 Array Biopharma, Inc. Substituirane imidazo (1,2b)piridazinske spojine kot Trk kinazni inhibitorji
CN102264736B (zh) 2008-10-22 2013-08-14 阵列生物制药公司 作为TRK激酶抑制剂的取代的吡唑并[1,5-a]嘧啶化合物
BRPI0914404A2 (pt) * 2008-10-31 2019-03-06 Genentech Inc "compostos, composição farmacêutica e método para tratar ou atenuar a gravidade de uma doença ou condição responsiva à inibição da atividade jak quinase em um paciente"
AR077468A1 (es) * 2009-07-09 2011-08-31 Array Biopharma Inc Compuestos de pirazolo (1,5 -a) pirimidina sustituidos como inhibidores de trk- quinasa
BR122019024201B1 (pt) * 2010-05-20 2021-08-03 Array Biopharma Inc Composto macrocíclico como inibidores de trk quinase, seu uso, e composição farmacêutica
WO2012030170A2 (ko) * 2010-08-31 2012-03-08 (주)아모레퍼시픽 카나비노이드 1 수용체 저해제로 작용하는 신규 화합물
US8796305B2 (en) * 2012-11-05 2014-08-05 Bayer Pharma Aktiengesellschaft Carboxy-substituted imidazo[1,2-a]pyridinecarboxamides and their use
TWI746426B (zh) 2014-11-16 2021-11-21 美商亞雷生物製藥股份有限公司 (S)-N-(5-((R)-2-(2,5-二氟苯基)-吡咯啶-1-基)-吡唑并[1,5-a]嘧啶-3-基)-3-羥基吡咯啶-1-甲醯胺硫酸氫鹽結晶型
CN114230571B (zh) * 2015-09-14 2025-07-08 无限药品股份有限公司 异喹啉酮的固体形式、其制备方法、包含其的组合物及其使用方法
EP3156405A1 (en) 2015-10-13 2017-04-19 Boehringer Ingelheim International GmbH Spirocyclic ether derivatives of pyrazolo[1,5-a]pyrimidine-3-carboxamide
EP3368039A1 (en) 2015-10-26 2018-09-05 The Regents of The University of Colorado, A Body Corporate Point mutations in trk inhibitor-resistant cancer and methods relating to the same
UA125026C2 (uk) 2016-04-04 2021-12-29 Локсо Онколоджі, Інк. РІДКІ КОМПОЗИЦІЇ (S)-N-(5-((R)-2-(2,5-ДИФТОРФЕНІЛ)ПІРОЛІДИН-1-ІЛ)ПІРАЗОЛО[1,5-a]ПІРИМІДИН-3-ІЛ)-3-ГІДРОКСИПІРОЛІДИН-1-КАРБОКСАМІДУ
UA125025C2 (uk) 2016-04-04 2021-12-29 Локсо Онколоджі, Інк. Способи лікування дитячих ракових захворювань
MX392604B (es) 2016-05-18 2025-03-24 Array Biopharma Inc Procesos para la preparacion de (s)-n-(5-((r)-2-(2,5-difluorofenil)pirrolidin-1-il)-pirazolo[1,5-a]pirimidin-3-il)-3-hidroxipirrolidin-1-carboxamida y sales del mismo.
JOP20190092A1 (ar) 2016-10-26 2019-04-25 Array Biopharma Inc عملية لتحضير مركبات بيرازولو[1، 5-a]بيريميدين وأملاح منها
JOP20190213A1 (ar) 2017-03-16 2019-09-16 Array Biopharma Inc مركبات حلقية ضخمة كمثبطات لكيناز ros1

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2003101993A1 (en) * 2002-06-04 2003-12-11 Neogenesis Pharmaceuticals, Inc. Pyrazolo` 1,5a! pyrimidine compounds as antiviral agents
US7329658B2 (en) * 2003-02-06 2008-02-12 Pfizer Inc Cannabinoid receptor ligands and uses thereof
US7176210B2 (en) * 2003-02-10 2007-02-13 Pfizer Inc. Cannabinoid receptor ligands and uses thereof
DE102004008807A1 (de) * 2004-02-20 2005-09-08 Bayer Cropscience Ag Pyrazolopyrimidine
WO2005103052A1 (en) * 2004-04-21 2005-11-03 Pfizer Products Inc. Pyrazolo [1,5-a] pyrimidin-7-one compounds and uses thereof
US8188097B2 (en) * 2005-10-21 2012-05-29 Mitsubishi Tanabe Pharma Corporation Pyrazolo[1,5-A]pyrimidine compounds
JP4847275B2 (ja) * 2005-10-21 2011-12-28 田辺三菱製薬株式会社 ピラゾロ［１，５−ａ］ピリミジン化合物

Similar Documents

Publication Publication Date Title
JP2026065113A (ja) ジペプチジルペプチダーゼ１阻害剤としての（２ｓ）－ｎ－［（１ｓ）－１－シアノ－２－フェニルエチル］－１，４－オキサゼパン－２－カルボキサミド
JP6218260B2 (ja) Ｊａｋ阻害剤としてのアミノピリミジニル化合物
CN105102451B (zh) N-苯基-氨甲酰衍生物及其作为药物用于治疗乙型肝炎的用途
KR102364134B1 (ko) 디아자비시클릭 치환된 이미다조피리미딘 및 호흡 장애의 치료를 위한 그의 용도
JP5166280B2 (ja) ピリミジン誘導体
CN109476665B (zh) 取代的二氮杂杂双环化合物及其用途
CN104995186B (zh) 经取代的双环二氢嘧啶酮及其作为嗜中性粒细胞弹性蛋白酶活性的抑制剂的用途
US9777002B2 (en) Inhibitors of the renal outer medullary potassium channel
JP4846665B2 (ja) ピラゾロ［１，５−ａ］ピリミジン化合物
ES2807785T3 (es) Compuestos de heteroarilamina bicíclicos como inhibidores de pi3k
RU2009120389A (ru) Гетероциклические соединения в качестве противовоспалительных агентов
TW201619159A (zh) 吡咯并［２，３－ｄ］嘧啶衍生物
WO2013064467A1 (en) Azetidine compounds, compositions and their use as inhibitors of soluble epoxide hydrolase
KR20010113829A (ko) 제약학적 활성 신규 화합물
JP6672288B2 (ja) 腫瘍の治療のためのｍｉｄｈ１阻害剤としての１−シクロヘキシル−２−フェニルアミノベンゾイミダゾール
TW200528440A (en) 2-cyanopyrrolidinecarboxamide compound
ES3037418T3 (en) 3-azabicyclo(3.1.0)hexane derivatives having kdm5 inhibitory activity and use thereof
RU2014106999A (ru) Замещенные производные 3-тиазолоаминопропионовой кислоты и их применение в качестве фармацевтических препаратов
JP2024041835A (ja) 置換テトラヒドロシクロペンタ［ｃ］ピロール、置換ジヒドロピロリジン、その類似体、およびそれらを使用する方法
JP2009514980A5 (enExample)
JP7025542B2 (ja) Ｔｇｆ－ベータ阻害剤としてのオキサジアゾール及びチアジアゾール
HK40122921A (en) Cannabinoid receptor 1 antagonists/inverse agonists and uses thereof
HK40066722A (en) Subsituted diazaheterobicyclic compounds and use thereof
HK40047161B (en) Substituted tetrahydrocyclopenta[c]pyrroles, substituted dihydropyrrolizines, analogues thereof, and methods using same
EA046988B1 (ru) Модуляторы пути интегрированной реакции на стресс