JP2008110944A - Deodorant composition - Google Patents

Abstract

<P>PROBLEM TO BE SOLVED: To provide a new deodorant composition that has an excellent deodorization function and is obtained at a low cost. <P>SOLUTION: The deodorant composition contains Quercus salicina extract and peroxidase. The blending ratio of the peroxidase to the Quercus salicina extract (peroxidase/Quercus salicina extract) is preferably 0.001 to 1 by weight. <P>COPYRIGHT: (C)2008,JPO&INPIT

Description

  The present invention relates to a deodorant composition containing an extract of Vulgaris.

  Bad breath is mainly caused by volatile sulfur compounds such as methyl mercaptan, which causes discomfort to many people. Conventionally, various deodorants have been developed and proposed to remove bad breath. Among these, various deodorizers using plant extracts have been proposed in consideration of safety to the human body (for example, see Patent Documents 1 and 2).

  However, the deodorant has a problem that the deodorizing power is weak and the effect is insufficient, and if the deodorant is blended in a large amount in the food, the flavor and color tone are adversely affected.

  Therefore, as a deodorant having a strong deodorizing power and safe to use, a deodorant (see Patent Document 3) using a plant extract as an active ingredient for bad breath and an oxidoreductase in combination with a specific plant extract and a phenolic compound A deodorant (see Patent Document 4) that uses an enzyme that oxidizes odorase has been proposed.

JP-A-57-204278 JP-A 61-240960 JP-A 63-309269 JP 10-212221 A

  However, although the deodorizer described in Patent Document 4 exhibits a certain degree of deodorizing action, it cannot be said that the amount of enzyme used for the plant extract is large and is sufficiently satisfactory in terms of cost.

  This invention is made | formed in view of the said situation, The objective is to provide the novel deodorant composition excellent in the deodorizing effect | action at low cost.

  Among the plant extracts, the present inventors pay attention to the extract of the moth beetle, and when used together with the extract of the moth beetle and peroxidase, even if the oxidase extract contains only a small amount of peroxidase, it has an excellent deodorizing effect. As a result, the present invention was completed.

That is, the gist of the present invention is as follows.
[1] A deodorant composition comprising an extract of radish and peroxidase,
[2] The deodorant composition according to the above [1], wherein the peroxidase / back beetle extract (weight ratio) is 0.001-1.
[3] A food containing the deodorant composition according to [1] or [2],
[4] The food according to [3], wherein the food is chewing gum.

  ADVANTAGE OF THE INVENTION According to this invention, the deodorant composition excellent in the deodorizing effect | action at low cost can be provided.

  The deodorant composition of the present invention is characterized in that it contains a mulberry extract and peroxidase.

  Vulgaris are evergreen trees of the beech family, and the leaves and twigs dried and ground are usually used as raw materials for extraction. Vulgaris extract can be produced by extracting the above extraction raw material using an extraction solvent.

  The extraction solvent is preferably a polar solvent, and examples thereof include water, lower aliphatic alcohols, and mixtures thereof. Examples of the lower aliphatic alcohol include ethanol, propanol, isopropanol, butanol, 1,3-butylene glycol, ethylene glycol, propylene glycol, and isoprene glycol. Of the above, water is particularly preferred. When water-containing lower aliphatic alcohol is used as the extraction solvent, the amount of alcohol contained therein can be 10 to 90% by weight.

  The water used as the extraction solvent is not particularly limited. For example, pure water, tap water, well water, or those subjected to various treatments such as ion exchange, membrane treatment, filtration, heat sterilization, distillation, and pH adjustment should be used. Can do.

  Various extraction methods can be appropriately employed depending on the nature of the extraction raw material. As an example, there may be mentioned a method of adding 3 to 20 times as much polar solvent to dried crumpled leaves and twigs, impregnating or stirring, and performing extraction. The extraction time is preferably 30 minutes to 1 day, and the extraction temperature is preferably room temperature to 100 ° C.

  The extraction operation may be performed once, but a polar solvent may be further added to the residue of crumpled leaves and twigs collected after extraction, and the extraction operation may be performed again. Extracts obtained by a plurality of extraction operations can be combined as one extract, or any one of the extracts can be used as the extract.

  The form of the extract of Vulgaris is not particularly limited, and examples thereof include, in addition to the extract itself, a diluted solution of the extract, a concentrated solution, a lyophilized product, or a purified product obtained through fractionation or purification treatment.

  In addition, before extracting with a polar solvent, a nonpolar solvent (for example, hexane, benzene, toluene, etc.) may be added to the extraction raw material, and the fat-soluble component may be dissolved in the nonpolar solvent and removed.

  In order to further enhance the functionality of the extract of moths, for example, purification treatment such as activated carbon treatment, adsorption resin treatment, ion exchange resin treatment, etc. can be carried out alone or in combination as appropriate. Moreover, in order to handle the extract easily, processing such as formulation can be performed.

  Peroxidase can be extracted from cruciferous horseradish (Armoracia rusticana), cruciferous radish (Rahpauns acanthiformis) or cucumber cucumber (Cucumis sativus), or fungi (Alternaria, Aspergillus oryzae, Coprinus cinereus, Oidiodendron) From a culture solution of Bacillus), it is obtained by extraction with water from cold to room temperature, or concentrated and purified from cold to room temperature. Since peroxidase is easily available, it is preferable to use a commercially available product.

  The above-described extract of mulberry or peroxidase alone does not exhibit an excellent deodorizing effect, and an excellent deodorizing effect is exhibited by using both in combination. Such an excellent deodorizing effect can be achieved by blending a very small amount of peroxidase with the extract of Vulgaris. Specifically, the blending amount of peroxidase with respect to the extract of moths is preferably 0.001 to 1, more preferably 0.001 to 0.1, and more preferably 0.001 to 0.1. 01 is particularly preferred. When the peroxidase / backspoil extract (weight ratio) is less than 0.001, the deodorizing action is weakened. On the other hand, if the peroxidase / backspoil extract (weight ratio) exceeds 1, the cost increases, which is not preferable.

  In the deodorant composition of the present invention, in order to prevent dental caries, etc., the oral cavity which generates glucosyltransferase inhibitor, plaque formation inhibitor, dental caries, periodontal disease, etc. in addition to the extract of radish and peroxidase Antimicrobial agents, anti-inflammatory agents or other deodorizing agents against endopathogenic bacteria can be included.

  Examples of the glucosyltransferase inhibitor and the plaque formation inhibitor include radish, sorghum, burdock, lobster, elephant, turmeric, shinyi, kouka, sesame, pheasant, licorice, gentian, senna, assembly, glaze, cocoon, kemponashi, loquat, Examples include various extracts such as Maikai, Hermanus, Tamarind, Orange, Eucalyptus, Jujube, Grape Seed, and Grape Leaf.

  Examples of the antibacterial agent against the oral pathogenic bacteria include cetylpyridinium chloride, triclosan, benzalkonium chloride, benzethonium chloride, cocophosphatidyl-dimonium, trichlorocarbanide, zinc pyrithione, isopropylmethylphenol, applephenone, hinokitiol, polylysine, Examples include green tea extract, catechin, mulberry bark extract, ginkgo biloba extract, thymol, methyl salicylate, eugenol, 1,8-shioner, menthol and the like.

  As an anti-inflammatory agent, for example, Asenyak, Vulture, Ogon, Licorice, Psycho, Hawthorn, Perilla, Glaze, Mulberry white skin, Kyonin, Taiso, Clove, Tonin, Nutmeg, Mace, Thyme, Thyme, Buttonpi, Azulene, Allantoin, Glycyrrhizin, And tranexamic acid.

  Examples of other deodorants include cinnamon, clove, nutmeg, mace, thyme, perilla, ginkgo biloba, persimmon leaf, oolong tea, copper chlorophyllin sodium, maltol and the like.

  In addition to the above-mentioned optional components, the deodorant composition of the present invention includes known additions such as surfactants, binders, wetting agents, sweeteners, preservatives, fragrances, and pigments, depending on applications. An agent can be included. Examples of the surfactant include sucrose fatty acid esters. Examples of the binder include carboxymethyl cellulose, hydroxyethyl cellulose, sodium alginate, carrageenan, gum arabic and the like. Examples of the wetting agent include polyethylene glycol, sorbitol, glycerin, propylene glycol and the like. Examples of the sweetener include saccharin, stevioside, glycyrrhizin, thaumatin, aspartame, acesulfame K, sucralose and the like. Examples of the preservative include dehydroacetic acid, benzoic acid, and parabens. Examples of the fragrance include menthol, menthone, carvone, eugenol, thymol, anethole, peppermint oil, peppermint oil, spearmint oil, eucalyptus oil, ginger oil, anise oil and the like.

  The deodorant composition of the present invention can remove malodor, but examples of the malodorous substance include methyl mercaptan which causes bad breath.

  The deodorant composition of this invention is normally mix | blended as an additive raw material of a foodstuff. Although the kind of foodstuff is not specifically limited, For example, confectionery (for example, chewing gum, (gummy) candy, tablet confectionery, etc.), a film-like foodstuff, etc. can be illustrated. The amount added to the food can be appropriately changed depending on the release rate when ingested, the dissolution concentration, and the preference, but usually, the food contains 0.0001 to 10% by weight of the extract of velvet leaf, Preferably, 0.005 to 1% by weight is contained.

  Hereinafter, the present invention will be described in more detail with reference to test examples and the like, but the present invention is not limited thereto.

1. Example of Production of Vulgaris Extract 50 g of dried ground pulverized leaf containing twigs of Vulgaris was added to 300 g of 300 g of distilled water and heated to reflux for 2 hours. The obtained extraction mixture was allowed to stand at room temperature and cooled, followed by filtration to separate into an extract and a residue. 300 g of distilled water was added to the residue, and heating under reflux, cooling and filtration were performed under the same conditions as described above. The obtained extract and the previously obtained extract were combined into one, and then concentrated under reduced pressure to obtain 4.2 g of an extract of moths.

2. Deodorization test 1
A deodorization test was conducted on methyl mercaptan, which is a typical malodor component of bad breath. In order to simulate the condition in the oral cavity, 20 ml of 0.1 M phosphate buffer (pH 7.2) was added to a 100 ml vial that can be sealed, and then the deodorization shown in Table 1 was applied to the phosphate buffer. The agent was added to 0.001% (w / v) based on the extract of the velvet leaf extract (in the case of peroxidase alone, based on the peroxidase), and then 0.1 ml of 100 ppm methyl mercaptan solution was added. . The vial was immediately sealed, and each test sample was kept at 37 ° C. for 30 minutes, and then 50 ml of gas in the vial was sucked with a Kitagawa type detection tube (Mercaptans, No. 130U), and the amount of methyl mercaptan was measured. . The deodorization rate (%) was calculated using as a control the test group in which only the phosphate buffer was added without adding the deodorant. The results are shown in Table 1. In addition, as the deodorant component, the extract of the moth beetle used is the one produced in the above-mentioned “1. Production example of the moth beak extract”, and the peroxidase is derived from horseradish manufactured by Oriental Yeast Co. (specific activity: 450 U). / Mg) was used.

  From Table 1, at this test concentration, the deodorizing effect of the extract of the moth bee alone (test group 5) was as weak as 10%, and the deodorizing effect was not seen at all with the peroxidase alone (test group 6). On the other hand, the deodorization effect was enhanced at any combination ratio when the extract of perchase and peroxidase were used in combination. In particular, peroxidase enhanced the deodorizing action with respect to the extract of Vulgaris persimmons with a very small addition amount. Specifically, in test group 3, it was revealed that a high deodorizing effect can be exhibited with a very small amount of peroxidase / backspoiled extract (weight ratio) = 0.001. In addition, the test group 4 (peroxidase / backspoiled extract (weight ratio) = 0.0001) also shows a tendency to enhance the deodorizing effect, and the composition using both the backspoiled extract and a small amount of peroxidase has an excellent deodorizing effect. It became clear to bring about.

3. Production Examples of Chewing Gum Chewing gum was produced according to the following Formulation Example 1 and Formulation Example 2, and as described later, in order to examine the deodorizing effect of the obtained chewing gum extract, flavor and texture when eating the gum Provided.

<Formulation example 1> (Product of the present invention)
Vulture extract 0.01g
Peroxidase 0.0001g
Gum base 35g
Calcium carbonate 2g
Maltitol 55g
Xylitol 5g
Fragrance for gum 1g

<Formulation example 2> (control product)
Vulture extract 0.01g
Gum base 35g
Calcium carbonate 2g
Maltitol 55g
Xylitol 5g
Fragrance for gum 1g

4). Deodorization test 2
In order to examine the deodorizing effect of the chewing gum obtained in “3. Production example of chewing gum”, the deodorizing effect of the chewing gum extract was examined. First, each of the chewing gums of Formulation Example 1 and Formulation Example 2 was chopped and powdered by a pulverizer, and then 50 ml of 0.1 M phosphate buffer (pH 7.2) was added to 10 g of each powdered chewing gum at room temperature. For 1 hour followed by 10 minutes at 37 ° C. Next, the extraction mixture was subjected to solid-liquid separation by filtration to obtain each chewing gum extract. 20 ml of each chewing gum extract was added to a 100 ml capacity sealable vial and 0.1 ml of 100 ppm methyl mercaptan solution was added. The vial was immediately sealed, and each test sample was kept at 37 ° C. for 30 minutes, and then 50 ml of gas in the vial was sucked with a Kitagawa type detection tube (Mercaptans, No. 130U), and the amount of methyl mercaptan was measured. . The deodorization rate (%) was calculated using the test group to which only the phosphate buffer was added without adding the deodorant as a control. Table 2 shows the results.

  From Table 2, it was demonstrated that Formulation Example 1 has a higher deodorizing effect than Formulation Example 2, and that chewing gum (the product of the present invention) using a combination of a maggot extract and peroxidase has a higher deodorizing effect.

5. Flavor and Texture Six chewing gums of Formulation Example 1 and Formulation Example 2 were tasted four times without notifying the chewing gum content and sample timing, and the chewing gum of Formulation Example 1 was almost the same as Formulation Example 2. Taste and texture were exhibited. From this, it was found that the addition of peroxidase had no effect on food.

  INDUSTRIAL APPLICABILITY The present invention can be widely used as a deodorant composition having a low cost and an excellent deodorizing effect.

Claims (4)

  A deodorant composition comprising an extract of radish and peroxidase.   The deodorant composition according to claim 1, wherein the peroxidase / back leaf extract (weight ratio) is 0.001-1.   A food containing the deodorant composition according to claim 1 or 2.   The food according to claim 3, wherein the food is chewing gum.