JP2008099602A - 抗体遺伝子の可変領域における変異部位の分布状況の調節法 - Google Patents

抗体遺伝子の可変領域における変異部位の分布状況の調節法 Download PDF

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Publication number
JP2008099602A
JP2008099602A JP2006284624A JP2006284624A JP2008099602A JP 2008099602 A JP2008099602 A JP 2008099602A JP 2006284624 A JP2006284624 A JP 2006284624A JP 2006284624 A JP2006284624 A JP 2006284624A JP 2008099602 A JP2008099602 A JP 2008099602A
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JP
Japan
Prior art keywords
gene
seq
antibody
function
variable region
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JP2006284624A
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English (en)
Japanese (ja)
Inventor
Kunifumi Ota
邦史 太田
Waka Rin
ワカ リン
Hidemune Seo
秀宗 瀬尾
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
SAITAMAKEN CHUSHO KIGYO SHINKO
SAITAMAKEN CHUSHO KIGYO SHINKO KOSHA
Japan Science and Technology Agency
RIKEN Institute of Physical and Chemical Research
Chiome Bioscience Inc
Original Assignee
SAITAMAKEN CHUSHO KIGYO SHINKO
SAITAMAKEN CHUSHO KIGYO SHINKO KOSHA
Japan Science and Technology Agency
RIKEN Institute of Physical and Chemical Research
Chiome Bioscience Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
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Application filed by SAITAMAKEN CHUSHO KIGYO SHINKO, SAITAMAKEN CHUSHO KIGYO SHINKO KOSHA, Japan Science and Technology Agency, RIKEN Institute of Physical and Chemical Research, Chiome Bioscience Inc filed Critical SAITAMAKEN CHUSHO KIGYO SHINKO
Priority to JP2006284624A priority Critical patent/JP2008099602A/ja
Priority to PCT/JP2007/001139 priority patent/WO2008047480A1/fr
Publication of JP2008099602A publication Critical patent/JP2008099602A/ja
Pending legal-status Critical Current

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Immunology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Peptides Or Proteins (AREA)
JP2006284624A 2006-10-19 2006-10-19 抗体遺伝子の可変領域における変異部位の分布状況の調節法 Pending JP2008099602A (ja)

Priority Applications (2)

Application Number Priority Date Filing Date Title
JP2006284624A JP2008099602A (ja) 2006-10-19 2006-10-19 抗体遺伝子の可変領域における変異部位の分布状況の調節法
PCT/JP2007/001139 WO2008047480A1 (fr) 2006-10-19 2007-10-19 Procédé de régulation de la distribution de sites de mutation dans la région variable d'un gène d'anticorps

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP2006284624A JP2008099602A (ja) 2006-10-19 2006-10-19 抗体遺伝子の可変領域における変異部位の分布状況の調節法

Publications (1)

Publication Number Publication Date
JP2008099602A true JP2008099602A (ja) 2008-05-01

Family

ID=39313736

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2006284624A Pending JP2008099602A (ja) 2006-10-19 2006-10-19 抗体遺伝子の可変領域における変異部位の分布状況の調節法

Country Status (2)

Country Link
JP (1) JP2008099602A (fr)
WO (1) WO2008047480A1 (fr)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2015167011A1 (fr) * 2014-05-02 2015-11-05 株式会社カイオム・バイオサイエンス Cellules pour la production d'anticorps humain

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2685714C (fr) 2007-05-31 2016-04-12 University Of Washington Mutagenese inductible de genes cibles
FI3521307T3 (fi) 2016-09-30 2023-04-03 Chiome Bioscience Inc Menetelmä vasta-aineiden saamiseksi
EP3974521A1 (fr) 2017-02-10 2022-03-30 Chiome Bioscience Inc. Procédé favorisant la diversification d'une région variable d'anticorps

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN100379862C (zh) * 2002-07-30 2008-04-09 独立行政法人理化学研究所 增强体细胞同源重组的方法和构建特异抗体的方法

Cited By (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2015167011A1 (fr) * 2014-05-02 2015-11-05 株式会社カイオム・バイオサイエンス Cellules pour la production d'anticorps humain
CN106414717A (zh) * 2014-05-02 2017-02-15 凯奥目生物科学株式会社 产生人抗体的细胞
JPWO2015167011A1 (ja) * 2014-05-02 2017-04-20 株式会社カイオム・バイオサイエンス ヒト抗体を産生する細胞
JP2020099341A (ja) * 2014-05-02 2020-07-02 株式会社カイオム・バイオサイエンス ヒト抗体を産生する細胞
CN112877292A (zh) * 2014-05-02 2021-06-01 凯奥目生物科学株式会社 产生人抗体的细胞
JP7236741B2 (ja) 2014-05-02 2023-03-10 株式会社カイオム・バイオサイエンス ヒト抗体を産生する細胞

Also Published As

Publication number Publication date
WO2008047480A1 (fr) 2008-04-24

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