JP2008069133A - Composition for slimming body - Google Patents

Abstract

<P>PROBLEM TO BE SOLVED: To provide a composition for slimming bodies, which combinedly uses Ilex paraguarienesis to synergistically improve the slimming effect. <P>SOLUTION: This composition for slimming the bodies comprises Ilex paraguarienesis, and one or more selected from bittern, Fucus evanescens and Zingiber officinale to synergistically improve the slimming effect. The composition for slimming the bodies can be used for all of external uses and oral uses. <P>COPYRIGHT: (C)2008,JPO&INPIT

Description

  The present invention relates to a slimming composition that exhibits an excellent slimming effect.

  Conventionally, for the purpose of slimming effect, medicinal ingredients such as caffeine, evergreen ivy extract, hamamelis extract, green tea extract, black tea extract, oolong tea extract, seaweed extract and the like are blended in the slimming composition. Recently, an aldose reductase inhibitor (see Patent Document 1) that prevents various complications of diabetes containing mate tea as an active ingredient, a gel-like thermal massage material containing ginger tincture (see Patent Document 2), and a kizuta extract Furthermore, slimming cosmetics (see Patent Document 3) containing Hibamata extract and parsley extract are known.

JP 2002-255837 A Japanese Patent Laid-Open No. 11-12126 JP 2004-59520 A

  However, slimming compositions containing these medicinal ingredients are not effective enough, or if a sufficient amount is added to obtain medicinal effects, the feeling of use may be impaired, or the odor / discoloration There was a problem in the stability of the dosage form, and the improvement was desired.

  As a result of intensive studies to achieve the above object, the present inventors have found that the above problem can be solved by using mate and a specific slimming active ingredient in combination, and the present invention has been completed. It was.

  That is, the present invention provides a slimming composition containing one or more selected from bittern, hibamata, and ginger and mate.

  ADVANTAGE OF THE INVENTION According to this invention, the composition for slimming which has the outstanding slimming effect and can be applied in wide field | areas, such as a skin external preparation and food-drinks, can be provided.

  An embodiment of the present invention will be described.

  The slimming composition of the present invention contains one or more selected from bittern, hibamata and ginger and mate.

  Next, the above components will be described.

  The bitter melon uses a liquid obtained by crystallization of salt from seawater, a dried product thereof, or an artificially mixed mineral. The composition of bittern varies depending on the production area, salt production method (ion exchange membrane method, sun method, salt field method or evaporation method), temperature at the time of salt crystallization, salt concentration and pressure at the time of salt crystallization, and other conditions. However, bittern prepared using seawater as a raw material is highly effective.

  Hibamata is a kind of brown algae belonging to the family Hibamata, and any type of algae belonging to the genus Hibamata can be used. It is convenient to use whole algae as the site of use.

Ginger ( Zingiber officinale ROSCOE) used in the present invention is a plant belonging to the family Ginger, and its rhizome is used.

The yerba mate ( Ilex paraguariensis ) used in the present invention is a plant belonging to the family Viraceae, and yerba mate is produced from its leaves and used for drinking.

  In the present invention, the above plants and algae are used. The plant and algae can be used after being pulverized as they are, but an extract can also be used. In the extraction, the raw material may be used as it is. However, in consideration of the extraction efficiency, it is preferable to perform the extraction after performing processing such as shredding, drying, and pulverization. The extraction can be performed by immersing in an extraction solvent or by an extraction method using a supercritical fluid or a subcritical fluid. In order to increase the extraction efficiency, homogenization may be performed in stirring or an extraction solvent. The extraction temperature is suitably about 5 ° C. to the boiling point of the extraction solvent. The extraction time varies depending on the type of extraction solvent and the extraction temperature, but it is appropriate to set it to about 1 hour to 14 days.

  Extraction solvents include water, lower alcohols such as methanol, ethanol, propanol and isopropanol, polyhydric alcohols such as 1,3-butylene glycol, propylene glycol, dipropylene glycol and glycerin, ethers such as ethyl ether and propyl ether. , Solvents such as esters such as butyl acetate and ethyl acetate, and ketones such as acetone and ethyl methyl ketone can be used, and one or more of these can be selected and used. Further, physiological saline, phosphate buffer, phosphate buffered saline, or the like may be used. Furthermore, you may use 1 type, or 2 or more types of supercritical fluids and subcritical fluids, such as water, a carbon dioxide, ethylene, propylene, ethanol, methanol, ammonia. It is also possible to extract under pressure using an autoclave or the like.

  Extracts of the above-mentioned solvents of plants and algae can be used as they are, but the concentrated and dried solids can be used again by dissolving them in water or a polar solvent, and their physiological effects are not impaired. It may be used after performing purification treatment such as decolorization, deodorization and desalting, and fractionation treatment by column chromatography. The above-mentioned extract of the genus Planta, its processed product and fractions thereof can be freeze-dried after each treatment and fractionation and dissolved in a solvent at the time of use.

  The slimming effect of the slimming composition of the present invention is synergistically improved by using mate with one or more selected from bittern, hibamata and ginger. In the composition for slimming of the present invention, the compounding ratio of one kind or two or more kinds selected from mate, bittern, hibamata, ginger is not particularly limited, and is selected from bittern, hibamata, ginger with respect to 1 part by mass of mate. 1 type or 2 types or more are 0.01-100 mass parts.

  The slimming composition of the present invention can be used as a slimming oral preparation in addition to a slimming skin external preparation.

  The dosage form of the external preparation for slimming is arbitrary, and can be provided as a solubilizing system such as lotion, an emulsifying system such as cream or milky lotion, or a dispersing system such as calamine lotion. Furthermore, it can also be provided in various dosage forms such as aerosols, ointments, powders and granules filled with a propellant. The blending amount of the slimming composition of the present invention when blended with an external preparation can be adjusted depending on the type of external preparation and the purpose of use. 0001-50.0 mass% is preferable, More preferably, it is 0.001-25.0 mass%.

  In addition to the slimming composition, the external preparation for blending the slimming composition is usually blended with pharmaceuticals, quasi-drugs, skin cosmetics, hair cosmetics and cleaning agents as necessary. Oily ingredients, moisturizers, powders, pigments, emulsifiers, solubilizers, detergents, UV absorbers, thickeners, drugs, fragrances, resins, antibacterial / antifungal agents, alcohols, etc. it can. Moreover, in the range which does not impair the effect of this invention, combined use with another moisturizer, a cell activator, or an antioxidant is also possible.

  The slimming composition of the present invention can be used as a slimming oral preparation by using it as a quasi-drug, a component of food or drink, a food additive, or the like. The use enables daily and continuous intake of the slimming composition having the slimming effect of the present invention. Examples of use of the slimming composition of the present invention as a food material include functional foods having a slimming effect or a preventive effect, health foods, general foods (juices, confectionery, processed foods, etc.), nutritional supplements (nutrient drinks) Etc.).

  Although the production example of the plant / algae extract used in the slimming composition of the present invention, the test for evaluating each action, the formulation example as a skin external preparation or food, and the use test will be described in more detail below. The technical scope of the present invention is not limited at all by this.

[Extraction method 1]
100 g of a dry pulverized product of plants and algae was dispersed in 2.0 kg of 50 vol% ethanol aqueous solution and extracted at room temperature for 2 hours with stirring. The extract supernatant was filtered off, concentrated under reduced pressure, and then lyophilized to obtain an extract.

[Extraction method 2]
100 g of dried pulverized plant / algae was extracted by heating with 2.0 kg of hot water for 20 minutes. The extract supernatant was filtered and lyophilized to obtain an extract.

  Production examples of plant / algae extracts are summarized in Table 1.

  The formulation example which mix | blended the composition for slimming using the said manufacture example is shown.

[Prescription Example 1] Massage pack
(1) Concentrated glycerin The total amount becomes 100 (mass%)
(2) Purified water 0.80
(3) Acrylic acid / alkyl methacrylate copolymer 0.33
(4) Carboxyvinyl polymer 0.08
(5) Paraoxybenzoic acid ester 0.10
(6) Polyethylene glycol 400 8.00
(7) Dimethylpolysiloxane 3.00
(8) Polyoxyethylene sorbitan monolaurate
(20 EO) 2.50
(9) Sodium hydroxide (10 mass% aqueous solution) 0.40
(10) Fragrance 0.05
(11) Production Example 1 (mate) 0.05
(12) Components shown in Table 2 0.05
Production method: Components (1) to (11) are mixed and homogenized to prepare a massage pack.

  In the massage pack formulation shown in Formulation Example 1, the components shown in Table 2 were blended to prepare massage packs according to Examples 1-8. At the same time, in the same formulation, a comparative example was prepared in which components (11) and (12) were replaced with the components shown in Table 2.

Use tests were conducted using Examples 1 to 8 and Comparative Examples 1 to 9. In the use test, a total of 10 males and females aged 20 to 50 who care about obesity were used as a group, and the examples or comparative examples were used blind once a day for 2 weeks, and the waist before and after use was measured. The results are summarized in Table 3.
Judgment standard average reduced by more than 3.0cm: ◎
Average decrease from 1.0 cm to less than 3.0 cm: ○
Average change in size before and after use is less than 1.0 cm: Δ
Average increase over 1.0 cm: ×

  As shown in Table 3, all the examples of the present invention exhibited a good slimming effect. On the other hand, although the comparative example contained 3 times the amount of the active ingredient as the corresponding example, its slimming effect was not as good as that of the example. That is, in the slimming composition of the present invention, it is clear that the slimming effect is synergistically improved by using guarana and a specific component in combination.

[Prescription Example 2] Warm massage
(1) Glycerin 88.97 (mass%)
(2) Ethanol 0.12
(3) Carrageenan 0.23
(4) Xanthan gum 0.23
(5) Methyl paraoxybenzoate 0.05
(6) Fragrance 0.20
(7) Silicic anhydride 10.00
(8) Production Example 1 (mate) 0.10
(9) Production Example 2 (Hibamata) 0.10
Manufacturing method: All ingredients are mixed and homogenized to prepare a warm massage.

[Prescription Example 3] Aerosol-type massage fee
(1) 2-alkyl-N-carboxymethyl 0.375 (mass%)
-N-hydroxyethylimidazolinium betaine
(2) l-menthyl glyceryl ether 0.025
(3) Allantoin 0.005
(4) Ethanol 3.750
(5) Citric acid 0.005
(6) Dipotassium glycyrrhizinate 0.005
(7) Production Example 1 (mate) 0.007
(8) Production Example 2 (Ginger) 0.005
(9) Purified water 20.823
(10) Isobutane (propellant) 75.000
Production method: All components other than isobutane are mixed and homogenized, and then filled into an aerosol container together with isobutane.

[Prescription Example 4] Body Gel
(1) 1,3-butylene glycol 2.00 (mass%)
(2) 2-Amino-2-methyl-1-propanol 0.30
(3) l-menthyl glyceryl ether 0.01
(4) Xanthan gum 0.50
(5) Polyethylene glycol 1540 1.00
(6) Polyoxyethylene (50EO) hydrogenated castor oil 0.20
(7) Production Example 1 (mate) 0.05
(8) Bittern 0.05
(9) Fragrance 0.10
(10) Ethanol 40.00
(11) Purified water 55.79
Manufacturing method: A body gel is prepared by mixing and homogenizing all ingredients.

[Formulation Example 5] Bar soap
(1) Soap base 96.000 (mass%)
(2) Sodium alginate 0.004
(3) Edetate tetrasodium tetrahydrate 0.200
(4) Citric acid 0.020
(5) Lactic acid 0.010
(6) Production Example 1 (mate) 0.010
(7) Production Example 2 (Hibamata) 0.010
(8) Purified water 3.746
Manufacturing method: After mixing and homogenizing all components, solid soap is prepared by press molding.

[Prescription Example 12] Bath salt
(1) Fragrance 0.300 (mass%)
(2) Production Example 1 (mate) 0.010
(3) Production Example 3 (Ginger) 0.010
(4) Sodium bicarbonate 49.000
(5) Sodium sulfate 50.680
Manufacturing method: All components are mixed uniformly.

[Prescription Example 15] Beverage
(1) Production Example 1 (mate) 0.01 (mass%)
(2) Production Example 3 (Ginger) 0.01
(3) bittern 0.01
(4) Erythritol 1.00
(5) Citric acid 0.10
(6) Stevia 0.05
(7) Purified water 98.82
Manufacturing method: All components are mixed uniformly.

[Prescription Example 16] Tablet
(1) Production Example 1 (mate) 0.01 (mass%)
(2) Production Example 3 (Ginger) 0.01
(3) bittern 0.01
(4) Magnesium stearate 0.01
(5) Lactose 0.26
Production method: All components are mixed and tableted with a tableting machine to obtain a tablet having a diameter of 10 mm and a weight of 300 mg.

[Prescription Example 17] Powder
(1) Production Example 1 (mate) 0.01 (mass%)
(2) Production Example 3 (Ginger) 0.01
(3) bittern 0.01
(7) Reduced lactose 3.00
(8) Soybean oligosaccharide 3.00
(9) Erythritol 3.00
(10) Dextrin 81.00
(11) Purified water 9.97
Manufacturing method: Mix all ingredients and spray dry to make a powder.

Claims (1)

A slimming composition containing one or more selected from bittern, hibamata and ginger and mate.