JP2008050292A - Cosmetic composition - Google Patents

Cosmetic composition Download PDF

Info

Publication number
JP2008050292A
JP2008050292A JP2006227268A JP2006227268A JP2008050292A JP 2008050292 A JP2008050292 A JP 2008050292A JP 2006227268 A JP2006227268 A JP 2006227268A JP 2006227268 A JP2006227268 A JP 2006227268A JP 2008050292 A JP2008050292 A JP 2008050292A
Authority
JP
Japan
Prior art keywords
acid
flower
salt
oil
cosmetic composition
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2006227268A
Other languages
Japanese (ja)
Inventor
Akio Odera
章夫 大寺
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Croda Japan KK
Original Assignee
Croda Japan KK
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Croda Japan KK filed Critical Croda Japan KK
Priority to JP2006227268A priority Critical patent/JP2008050292A/en
Publication of JP2008050292A publication Critical patent/JP2008050292A/en
Pending legal-status Critical Current

Links

Landscapes

  • Cosmetics (AREA)

Abstract

<P>PROBLEM TO BE SOLVED: To provide a cosmetic excellent in a whitening effect. <P>SOLUTION: This cosmetic composition comprises (A) an extract of at least one kind selected from a Morus Nigra leaf, a Magnolia Biondii flower, Trifolium Pratense, a Lupinus Albus seed, Hypericum Perforatum, an Origanum Vulgare flower, Viola Tricolor, a Centaurea Cyanus flower, Melissa Officinalis, and a Calendula Officinalis flower and/or (B) an oil purified by column adsorption purification and/or (C) a whitening component. <P>COPYRIGHT: (C)2008,JPO&INPIT

Description

本発明は、化粧料に関し、さらに詳しくは、美白効果の高い化粧料に関する。本発明の化粧料は、基礎化粧品をはじめ、メイクアップ化粧品、浴剤などに好適に使用しうるものである。 The present invention relates to a cosmetic, and more particularly to a cosmetic having a high whitening effect. The cosmetic of the present invention can be suitably used for basic cosmetics, makeup cosmetics, bath preparations and the like.

従来、美白化粧料としては、様々なものが提案されている。たとえば、アスコルビン酸やコウジ酸、アルブチン等の美白成分を用いた化粧料である。(特許文献1参照)
特開2002−145759 特開昭62−205005 特開2004−89786
Conventionally, various skin whitening cosmetics have been proposed. For example, cosmetics using whitening ingredients such as ascorbic acid, kojic acid, and arbutin. (See Patent Document 1)
JP 2002-145759 A JP 62-205005 JP2004-89786

しかし、これらの美白化粧料は、美白効果の点で、必ずしも満足できるものではなかった。本発明者等は上記の事情に鑑み、鋭意研究した結果、本発明に到達したものであって、その目的とするところは、美白効果の高い化粧料を提供するところにある。 However, these whitening cosmetics are not always satisfactory in terms of the whitening effect. As a result of intensive studies in view of the above circumstances, the present inventors have reached the present invention, and the object of the present invention is to provide a cosmetic with a high whitening effect.

上述の目的は(A)クロミグワ葉(Morus Nigra Leaf)、ボウシュンカ花(Magnolia Biondii Flower)、アカツメクサ(Trifolium Pratense)、シロバナルーピン種子(Lupinus Albus Seed)、セイヨウオトギリソウ(Hypericum Perforatum)、ハナハッカ花(Origanum Vulgare Flower)、パンジー(Viola Tricolor)、ヤグルマギク花(Centaurea Cyanus Flower)、メリッサ(Melissa Officinalis)、トウキンセンカ花(Calendula Officinalis Flower)からなる群より選択される1種または2種以上の抽出物および/または(B)カラム吸着精製により精製された油剤および/または(C)美白成分を含有することを特徴とする化粧料によって達成される。 The above objectives are: (A) Morus Nigra Leaf, Bowshunka flower (Magnolia Biondii Flower), Red clover (Trifolium Pratense), White-spotted lupine seed (Lupinus Albus Seed), Hypericum Perforatum, Red-tailed flower (Origanum Vulgare) One or more extracts selected from the group consisting of Flower, Pansy (Viola Tricolor), Cornflower Cyanus Flower, Melissa Officinalis, Calendula Officinalis Flower and / or This is achieved by a cosmetic comprising (B) an oil agent purified by column adsorption purification and / or (C) a whitening component.

以上説明してきたように、本発明の化粧料は、美白効果を発揮することができる。  As described above, the cosmetic of the present invention can exhibit a whitening effect.

以下、本発明の実施の形態について詳細に説明する。本発明に用いられる植物抽出物は、抽出溶媒と共に浸漬または加熱還流した後、濾過し、濃縮して得られる。本発明に用いられる抽出溶媒は、通常抽出に用いられる物質であれば何でもよく、水、多価アルコールから選択される1種または2種以上の溶媒、特にグリセリン、プロピレングリコール、ブチレングリコール、ポリエチレングリコール、ジエチレングリコールモノエチルエーテル、ヘキシレングリコール等が望ましい。抽出物の配合量は、外用剤全量中、乾燥物として0.0005〜20.0重量%、好ましくは0.001〜10.0重量%である。0.0005重量%未満であると、本発明でいう効果が十分に発揮されず、20.0重量%を超えると製剤化が難しいので好ましくない。また、10.0重量%以上配合してもさほど大きな効果の向上はみられない。 Hereinafter, embodiments of the present invention will be described in detail. The plant extract used in the present invention is obtained by immersion or heating under reflux with an extraction solvent, followed by filtration and concentration. The extraction solvent used in the present invention is not particularly limited as long as it is a substance usually used for extraction, and one or more solvents selected from water and polyhydric alcohols, particularly glycerin, propylene glycol, butylene glycol, polyethylene glycol. Diethylene glycol monoethyl ether, hexylene glycol and the like are desirable. The blending amount of the extract is 0.0005 to 20.0% by weight, preferably 0.001 to 10.0% by weight as a dry product in the total amount of the external preparation. If the amount is less than 0.0005% by weight, the effect referred to in the present invention is not sufficiently exerted, and if it exceeds 20.0% by weight, it is difficult to make a preparation. Moreover, even if it mix | blends 10.0 weight% or more, the improvement of the big effect is not seen.

本発明の植物抽出物は通常の加熱抽出法で調製してもよいが、本発明者らの考案したマイクロ波抽出法(特開2004−89786)によって調製すると、着色の少なく、透明性に優れた、経時的に安定な植物抽出物を得ることができる。 The plant extract of the present invention may be prepared by a usual heat extraction method, but when prepared by the microwave extraction method devised by the present inventors (Japanese Patent Application Laid-Open No. 2004-89786), it is less colored and excellent in transparency. In addition, a plant extract that is stable over time can be obtained.

本発明に用いられる植物抽出物は、ヒトの肌に対してすぐれた美白効果を奏するものであるので、該植物抽出物が配合された化粧料も、すぐれた美白効果を示すことができる。 Since the plant extract used in the present invention has an excellent whitening effect on human skin, a cosmetic containing the plant extract can also show an excellent whitening effect.

(B)のカラム吸着精製された油剤がアボガド油、マカデミアナッツ油、シア脂、ユチャ油、テオブロマグランディフロルム種子脂、オリーブ油、メドフォーム油、ミツロウ、オレイン酸オレイル、パルミチン酸オクチル、イソノナン酸イソトリデシル、ミリスチン酸ミリスチル、エイコセン酸カプリリル、ラウリン酸ヘキシル、ラノリン、ワセリン、流動パラフィン、ミツロウ、スクワランから選ばれた1種または2種以上であることを特徴とする請求項1記載の老化防止用化粧料組成物。 (B) The oils purified by column adsorption are avocado oil, macadamia nut oil, shea fat, yucha oil, theobroma grandiflorum seed fat, olive oil, medoform oil, beeswax, oleyl oleate, octyl palmitate, isotridecyl isononanoate, myristic acid 2. The anti-aging cosmetic composition according to claim 1, wherein the cosmetic composition is one or more selected from myristyl, capryryl eicosenoate, hexyl laurate, lanolin, petrolatum, liquid paraffin, beeswax and squalane.

カラム吸着精製はクローダジャパン株式会社が考案したカラムクロマトグラフ的手法で(特開昭62−205005)、この方法によれば、上記油剤中の極性不純物を除去でき、無色、無臭で、皮膚刺激性が少なく、経時酸化安定性に優れた油剤を得ることができる。カラムクロマトグラフ的手法とは、原油を非極性溶媒に溶解し、これを吸着剤を充填した吸着塔に通液し、極性不純物を吸着除去し、ついで、非極性溶媒を留去する精製方法である。非極性溶媒としてはn−ヘキサン、n−ヘプタン、石油エーテルのような脂肪族炭化水素、吸着剤としては、例えば、シリカゲル、珪酸マグネシウム、活性白土、ゼオライト等、およびこれらの混合物があげられ、適宜選択できる。 Column adsorption purification is a column chromatographic method devised by Croda Japan Co., Ltd. (Japanese Patent Laid-Open No. Sho 62-205005). According to this method, polar impurities in the oil can be removed, and are colorless, odorless, and skin irritant. Therefore, it is possible to obtain an oil agent having a small amount of oxidation stability over time. The column chromatographic method is a purification method in which crude oil is dissolved in a nonpolar solvent, passed through an adsorption tower packed with an adsorbent, polar impurities are adsorbed and removed, and then the nonpolar solvent is distilled off. is there. Examples of the nonpolar solvent include aliphatic hydrocarbons such as n-hexane, n-heptane, and petroleum ether, and examples of the adsorbent include silica gel, magnesium silicate, activated clay, zeolite, and the like, and mixtures thereof. You can choose.

(C)の美白成分としては、アスコルビン酸、アスコルビン酸塩、アスコルビン酸リン酸マグネシウム塩、アスコルビン酸グルコシド、システイン、グルタチオン、グルタチオンの塩、N−アシルグルタチオン、グルタチオンのエステル、ハイドロキノン、ハイドロキノンの塩、ハイドロキノンの配糖体、フェルラ酸、フェルラ酸の塩、イソフェルラ酸、イソフェルラ酸の塩、カフェー酸、カフェー酸の塩、レゾルシノール類、エルゴ酸、エルゴ酸の塩、プラセンタエキス、カフェイン、タンニン、ベラパミル、トラネキサム酸、グラブリジン、酢酸トコフェロール、グリチルリチン酸、アルブチン、コウジ酸、エラグ酸、リノール酸、オレイン酸、リノレン酸、ジアセチルボルジン等が挙げられる。 As the whitening component of (C), ascorbic acid, ascorbic acid salt, ascorbic acid magnesium phosphate, ascorbic acid glucoside, cysteine, glutathione, glutathione salt, N-acylglutathione, glutathione ester, hydroquinone, hydroquinone salt, Hydroquinone glycoside, ferulic acid, ferulic acid salt, isoferulic acid, isoferulic acid salt, caffeic acid, caffeic acid salt, resorcinols, ergoic acid, ergoic acid salt, placenta extract, caffeine, tannin, verapamil , Tranexamic acid, grabridine, tocopherol acetate, glycyrrhizic acid, arbutin, kojic acid, ellagic acid, linoleic acid, oleic acid, linolenic acid, diacetylbordin and the like.

本発明で用いられる美白成分の含有量は、化粧料の総量を基準として、0.001−20.0%が好ましく、0.01−10.0%がより好ましく、特に、0.1−4.0%が好ましい。0.001%以上で、美白効果が現われ、20.0%以下で、美白効果が高く、コスト的に有利である。 The content of the whitening component used in the present invention is preferably 0.001-20.0%, more preferably 0.01-10.0%, especially 0.1-4 based on the total amount of the cosmetic. 0.0% is preferable. If it is 0.001% or more, the whitening effect appears, and if it is 20.0% or less, the whitening effect is high, which is advantageous in terms of cost.

本発明の化粧料には、上記必須成分以外に、通常化粧品や医薬品等の皮膚外用剤に用いられる成分、例えば、保湿剤、酸化防止剤、紫外線吸収剤、界面活性剤、増粘剤、アルコール類、粉末成分、色材、水性成分、水、各種皮膚栄養剤等を必要に応じて適宜配合することができる。 In addition to the above essential components, the cosmetics of the present invention are usually used in external preparations for skin, such as cosmetics and pharmaceuticals, such as moisturizers, antioxidants, ultraviolet absorbers, surfactants, thickeners, alcohols. , Powder components, coloring materials, aqueous components, water, various skin nutrients, and the like can be appropriately blended as necessary.

その他、エデト酸二ナトリウム、エデト酸三ナトリウム、クエン酸ナトリウム、ポリリン酸ナトリウム、メタリン酸ナトリウム、グルコン酸等の金属封鎖剤、各種生薬、グルコース、フルクトース、マンノース、ショ糖、トレハロース等の糖類なども適宜配合することができる。 In addition, there are metal sequestering agents such as disodium edetate, trisodium edetate, sodium citrate, sodium polyphosphate, sodium metaphosphate, gluconic acid, various herbal medicines, sugars such as glucose, fructose, mannose, sucrose, trehalose, etc. It can mix | blend suitably.

本発明は、外皮に適用される化粧料、医薬部外品等、特に好適には化粧料に広く適用することが可能であり、その剤型も水溶液系、可溶化系、乳化系、粉末系、油液系、ゲル系、軟膏系、エアゾール系、水−油2層系、水−油−粉末3層系等、幅広い剤型を採り得る。すなわち、基礎化粧品であれば、洗顔料,化粧水,乳液、クリーム、ジェル、エッセンス(美容液)、パック、マスク等の形態に、上記の多様な剤型において広く適用可能である。また、メーキャップ化粧品であれば、ファンデーション等、トイレタリー製品としてはボディソープ、石けん等の形態に広く適用可能である。さらに、医薬部外品であれば、各種の軟膏剤等の形態に広く適用が可能である。そして、これらの剤型及び形態に、本発明の美白化粧料の採り得る形態が限定されるものではない。 The present invention can be widely applied to cosmetics, quasi-drugs and the like, particularly preferably cosmetics, which are applied to the outer skin, and their dosage forms are also aqueous systems, solubilization systems, emulsification systems, powder systems. A wide range of dosage forms such as oil-liquid, gel-based, ointment-based, aerosol-based, water-oil two-layer system, water-oil-powder three-layer system can be adopted. That is, in the case of basic cosmetics, the above various dosage forms can be widely applied to forms such as face wash, lotion, milky lotion, cream, gel, essence (beauty serum), pack, mask and the like. In addition, makeup cosmetics can be widely applied to foundations and the like, and toiletries such as body soaps and soaps. Furthermore, if it is a quasi-drug, it can be widely applied to various ointment forms. And the form which the whitening cosmetics of this invention can take is not limited to these dosage forms and forms.

次に、本発明の美白化粧料を実施例に基づいてさらに詳細に説明するが、本発明はかかる実施例のみに限定されるものではない。配合量は重量%である。 Next, although the whitening cosmetics of this invention are demonstrated in detail based on an Example, this invention is not limited only to this Example. The blending amount is% by weight.

実施例1−3、比較例1−6
評価例 美白実用試験
表1に示す各組成の乳化型化粧料を常法により調製した。被験者10名を一群として、1MED量に相当する紫外線を左右の前腕内側部の1cmx1cmの面積に照射し、紅班とそれに続く黒化を生じさせた後、片方の黒化部位にコントロールを、もう片方の黒化部位に、各群ごとに実施例、比較例のいずれかの化粧料を、1日2回塗布し、1ヶ月間連用を行なった。コントロール塗布側の美白効果に比べたときの各実施例・比較例の美白効果を表2に示す評価基準に従って、パネラー自身が評価し、全パネラーの合計点数を以って評価結果とした。したがって、点数が高いほどコントロールに対する美白効果に優れていることを示す。結果を表3に示す。
Example 1-3, Comparative Example 1-6
Evaluation Example Whitening Practical Test Emulsified cosmetics having the compositions shown in Table 1 were prepared by a conventional method. A group of 10 test subjects was irradiated with ultraviolet rays equivalent to 1 MED amount to the 1 cm x 1 cm area of the inner part of the left and right forearms to cause erythema and subsequent blackening. The cosmetic material of any of the Examples and Comparative Examples was applied to one blackened portion for each group twice a day and used continuously for one month. According to the evaluation criteria shown in Table 2, the paneler himself evaluated the whitening effect of each of the examples and comparative examples when compared with the whitening effect on the control coating side, and the evaluation result was obtained by using the total score of all panelists. Therefore, it shows that it is excellent in the whitening effect with respect to control, so that a score is high. The results are shown in Table 3.

Figure 2008050292
Figure 2008050292


















Figure 2008050292
Figure 2008050292






Figure 2008050292
Figure 2008050292
























表3において、B成分のカラム精製油剤はスクワラン5%、流動パラフィン10%の合計15%を含有し、未精製油剤はカラム精製前の未精製スクワラン5%、流動パラフィン10%の合計15%を含有している。 In Table 3, the B component column refined oil contains 15% total of 5% squalane and 10% liquid paraffin, and the unrefined oil contains 15% total of unrefined squalane 5% and liquid paraffin 10% before column purification. Contains.

表1および表3より、(A)〜(C)の成分を全て含有する本発明の化粧料(実施例1−3)は、相乗的な美白効果を有することがわかる。これに対して、(C)成分のみの比較例1、(B)成分のみの比較例2、(A)成分のみの比較例3は、効果が低く、(A)〜(C)成分のいずれか1つを欠く比較例4−6も、効果が十分ではなかった。これらの比較例から(A)、(B),(C)の成分を組み合わせることが本発明の要件であることが明らかである。 From Table 1 and Table 3, it can be seen that the cosmetic (Example 1-3) of the present invention containing all the components (A) to (C) has a synergistic whitening effect. On the other hand, Comparative Example 1 with only the component (C), Comparative Example 2 with only the component (B), and Comparative Example 3 with only the component (A) have low effects, and any of the components (A) to (C) Comparative Example 4-6 lacking one of these was also not sufficiently effective. From these comparative examples, it is clear that combining the components (A), (B), and (C) is a requirement of the present invention.

Claims (3)

(A)クロミグワ葉(Morus Nigra Leaf)、ボウシュンカ花(Magnolia Biondii Flower)、アカツメクサ(Trifolium Pratense)、シロバナルーピン種子(Lupinus Albus Seed)、セイヨウオトギリソウ(Hypericum Perforatum)、ハナハッカ花(Origanum Vulgare Flower)、パンジー(Viola Tricolor)、ヤグルマギク花(Centaurea Cyanus Flower)、メリッサ(Melissa Officinalis)、トウキンセンカ花(Calendula Officinalis Flower)からなる群より選択される1種または2種以上の抽出物および/または(B)カラム吸着精製により精製された油剤および/または(C)美白成分を含有することを特徴とする化粧料組成物。 (A) Morus Nigra Leaf, Magnolia Biondii Flower, Red clover (Trifolium Pratense), White Pulp (Lupinus Albus Seed), Hypericum Perforatum, Origanum Vulgare Flower (Viola Tricolor), cornflower flower (Centaurea Cyanus Flower), Melissa (Melissa Officinalis), one or more extracts selected from the group consisting of calendula officinalis flower and / or (B) column A cosmetic composition comprising an oil agent purified by adsorptive purification and / or (C) a whitening component. (B)のカラム吸着精製により精製された油剤がアボガド油、マカデミアナッツ油、シア脂、ユチャ油、テオブロマグランディフロルム種子脂、オリーブ油、メドフォーム油、ミツロウ、オレイン酸オレイル、パルミチン酸オクチル、イソノナン酸イソトリデシル、ミリスチン酸ミリスチル、エイコセン酸カプリリル、ラウリン酸ヘキシル、ラノリン、ワセリン、流動パラフィン、ミツロウ、スクワランから選ばれた1種または2種以上であることを特徴とする請求項1記載の化粧料組成物。 Oils purified by column adsorption purification in (B) are avocado oil, macadamia nut oil, shea fat, yucha oil, theobroma grandiflorum seed fat, olive oil, medoform oil, beeswax, oleyl oleate, octyl palmitate, isotridecyl isononanoate, The cosmetic composition according to claim 1, wherein the cosmetic composition is one or more selected from myristyl myristate, caprylyl eicosenoate, hexyl laurate, lanolin, petrolatum, liquid paraffin, beeswax, and squalane. (C)の美白成分がアスコルビン酸、アスコルビン酸塩、アスコルビン酸リン酸マグネシウム塩、アスコルビン酸グルコシド、システイン、グルタチオン、グルタチオンの塩、N−アシルグルタチオン、グルタチオンのエステル、ハイドロキノン、ハイドロキノンの塩、ハイドロキノンの配糖体、フェルラ酸、フェルラ酸の塩、イソフェルラ酸、イソフェルラ酸の塩、カフェー酸、カフェー酸の塩、レゾルシノール類、エルゴ酸、エルゴ酸の塩、プラセンタエキス、カフェイン、タンニン、ベラパミル、トラネキサム酸、グラブリジン、酢酸トコフェロール、グリチルリチン酸、アルブチン、コウジ酸、エラグ酸、リノール酸、オレイン酸、リノレン酸、ジアセチルボルジンからなる群より選択された1種または2種以上であることを特徴とする請求項1記載の化粧料組成物。 The whitening component of (C) is ascorbic acid, ascorbic acid salt, ascorbic acid magnesium phosphate, ascorbic acid glucoside, cysteine, glutathione, glutathione salt, N-acyl glutathione, glutathione ester, hydroquinone, hydroquinone salt, hydroquinone salt Glycoside, ferulic acid, ferulic acid salt, isoferulic acid, isoferulic acid salt, caffeic acid, caffeic acid salt, resorcinols, ergoic acid, ergoic acid salt, placenta extract, caffeine, tannin, verapamil, tranexam It is characterized by being one or more selected from the group consisting of acids, grabrizine, tocopherol acetate, glycyrrhizic acid, arbutin, kojic acid, ellagic acid, linoleic acid, oleic acid, linolenic acid, diacetylbordin That claim 1 cosmetic composition.
JP2006227268A 2006-08-24 2006-08-24 Cosmetic composition Pending JP2008050292A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP2006227268A JP2008050292A (en) 2006-08-24 2006-08-24 Cosmetic composition

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP2006227268A JP2008050292A (en) 2006-08-24 2006-08-24 Cosmetic composition

Publications (1)

Publication Number Publication Date
JP2008050292A true JP2008050292A (en) 2008-03-06

Family

ID=39234669

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2006227268A Pending JP2008050292A (en) 2006-08-24 2006-08-24 Cosmetic composition

Country Status (1)

Country Link
JP (1) JP2008050292A (en)

Cited By (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2012058711A2 (en) * 2010-11-02 2012-05-10 Maureen Patricia Macnicol Composition
JP2013504607A (en) * 2009-09-16 2013-02-07 ボタニック センチュリー(ベイジン)カンパニー リミテッド Plant extract, composition containing the same, extraction method and use thereof
CN102972119A (en) * 2012-11-05 2013-03-20 溧阳市天目湖保健品有限公司 Magnolia biondii seed cultivation method
JP2013166713A (en) * 2012-02-14 2013-08-29 Ichimaru Pharcos Co Ltd Kinesin inhibitor
JP2014506596A (en) * 2011-02-22 2014-03-17 アクゾ ノーベル ケミカルズ インターナショナル ベスローテン フエンノートシャップ Composition containing bengal body, lotus and clover serum fractions (hyperpigmentation)
CN104095775A (en) * 2013-04-03 2014-10-15 上海珍馨化工科技有限公司 Emulsion for centaurea cyanus mask, centaurea cyanus mask and preparation method of centaurea cyanus mask
CN104306646A (en) * 2014-10-13 2015-01-28 徐艳 Soft capsule for treating nasosinusitiss as well as preparation method and application of soft capsule
KR20180080126A (en) 2016-12-01 2018-07-11 가부시키가이샤 호루스 Availability Method of producing flavant extract
JP2018172292A (en) * 2017-03-31 2018-11-08 株式会社コーセー Cosmetic or skin external preparation

Cited By (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2017226675A (en) * 2009-09-16 2017-12-28 ボタニック センチュリー(ベイジン)カンパニー リミテッド Plant extract, composition containing the same, and extraction method and use thereof
JP2013504607A (en) * 2009-09-16 2013-02-07 ボタニック センチュリー(ベイジン)カンパニー リミテッド Plant extract, composition containing the same, extraction method and use thereof
KR102167419B1 (en) * 2009-09-16 2020-10-19 버태닉 센추리 (베이징) 컴퍼니 리미티드 Plant extract, compositions containing same, method of extraction and uses thereof
KR20190044143A (en) * 2009-09-16 2019-04-29 버태닉 센추리 (베이징) 컴퍼니 리미티드 Plant extract, compositions containing same, method of extraction and uses thereof
JP2016102106A (en) * 2009-09-16 2016-06-02 ボタニック センチュリー(ベイジン)カンパニー リミテッド Plant extract, composition containing same, extraction method and uses thereof
WO2012058711A3 (en) * 2010-11-02 2012-11-29 Maureen Patricia Macnicol Composition comprising macadamia and calendula for promoting hair growth
WO2012058711A2 (en) * 2010-11-02 2012-05-10 Maureen Patricia Macnicol Composition
JP2014506596A (en) * 2011-02-22 2014-03-17 アクゾ ノーベル ケミカルズ インターナショナル ベスローテン フエンノートシャップ Composition containing bengal body, lotus and clover serum fractions (hyperpigmentation)
JP2013166713A (en) * 2012-02-14 2013-08-29 Ichimaru Pharcos Co Ltd Kinesin inhibitor
CN102972119A (en) * 2012-11-05 2013-03-20 溧阳市天目湖保健品有限公司 Magnolia biondii seed cultivation method
CN104095775A (en) * 2013-04-03 2014-10-15 上海珍馨化工科技有限公司 Emulsion for centaurea cyanus mask, centaurea cyanus mask and preparation method of centaurea cyanus mask
CN104306646A (en) * 2014-10-13 2015-01-28 徐艳 Soft capsule for treating nasosinusitiss as well as preparation method and application of soft capsule
KR20180080126A (en) 2016-12-01 2018-07-11 가부시키가이샤 호루스 Availability Method of producing flavant extract
JP2018172292A (en) * 2017-03-31 2018-11-08 株式会社コーセー Cosmetic or skin external preparation

Similar Documents

Publication Publication Date Title
JP2008050292A (en) Cosmetic composition
KR100970544B1 (en) Composition for preparation for external use on skin and method of using the same
RU2449782C2 (en) Vesicle applicable in medical product for external application to skin and medical product for external application to skin including vesicle
ES2700784T3 (en) Extract of aerial parts of Gynandropsis gynandra or Cleome gynandra and cosmetic, dermatological or pharmaceutical compositions comprising it
JP2008037812A (en) Cosmetic composition
ES2284870T3 (en) PHARMACEUTICAL AND / OR COSMETIC COMPOSITIONS FOR THE TREATMENT OF LOCATED ADIPOSITIES AND CELLULITIS.
KR20180138399A (en) Inhibitor for NO activator, Anit-inflammation agent containing of the same, Revitalizing cosmetics containing the same and Manufacturing method thereof
JPH0527605B2 (en)
JP2021042241A (en) Composition for external use
JP2008037764A (en) Sebum secretion inhibitor and skin external preparation for ameliorating acne
JP3415200B2 (en) External preparation for skin
JP2004262853A (en) Cosmetic
JP2549127B2 (en) Topical drug for suppressing melanin production
Saidi et al. Tunisian Clematis flammula essential oil enhances wound healing: GC-MS analysis, biochemical and histological assessment
JP2000143479A (en) Skin-bleaching cosmetic
JP2004075645A (en) Cosmetic
JP2003160461A (en) Skin care preparation
JPH01199916A (en) Drug for external use
JP2000169329A (en) Cosmetic composition
JP4035481B2 (en) Skin preparation
JP2009269851A (en) Inhibitor of prostaglandin e2 production and its utilization
KR102278167B1 (en) A cosmetic composition having prevention of lipid peroxidation, improved damaged skin and soothing effect on redness of skin
JP2894715B2 (en) External preparation for skin
JPH03200708A (en) Dermal external agent
KR20030047963A (en) Pore-Minimizing Cosmetic Composition for Controlling Sebum Containing Herb Extract