JP2008013204A - Liquid container - Google Patents

Abstract

<P>PROBLEM TO BE SOLVED: To provide a novel liquid container capable of separately filling liquid agents into a plurality of sections of the inside of the container separated by sealing means and capable of safely and sufficiently mixing the liquid agents aseptically when the liquid agents are mixed. <P>SOLUTION: The liquid container 1 comprises a container body 10, the sealing means 20, an injection opening 30, and a delivery opening 40. The container body 10 is cylindrical and has two sealing means 20 formed inside the container body 10 along a lengthwise direction. By closing the sealing means 20, the inside of the cylindrical container body 10 can be divided into three sections A, B, and C. Such a structure makes it possible to store liquids in sections A and C from the injection opening 30. By opening the sealing means 20 by a predetermined pulling force, the liquids stored in the sections A and C flow into the section B, and safely mixed in the section B aseptically without being contaminated in the section B. Accordingly, the mixed liquids can be delivered from the delivery opening 40 attached to the section B. <P>COPYRIGHT: (C)2008,JPO&INPIT

Description

The present invention relates to a liquid container used for mixing a plurality of chemical solutions such as dialysate used for peritoneal dialysis.

At present, a two-liquid mixed type chemical is mainly used as a dialysate used for peritoneal dialysis. Since one of these two liquids is a liquid having different properties such as acidic and the other is alkaline, the two liquids are mixed and used immediately before treatment. The liquid container used at that time is formed by heat-sealing a partition portion for dividing a sheet of a polymer material such as a vinyl chloride material into a plurality of sections, and also heats the inlet and the outlet for each section. Fused and assembled.

As a means for communicating a plurality of compartments of such a liquid container, first, in order to cut off the partition portion, if the pressure is applied by a means such as hitting the compartment, the heat fusion part is peeled off. is there. Examples thereof include US Pat. No. 4,458,811 (see Patent Document 1), US Pat. No. 4,608,043 (see Patent Document 2), US Pat. No. 5,577,369 (Japanese Patent Laid-Open No. 7-51342: Patent). Reference 3).

Secondly, there is one in which a break valve is attached to the partition part. Examples thereof include Japanese Patent Application Laid-Open No. 57-52455 (see Patent Document 4), US Pat. No. 4,396,383 (Japanese Patent Publication No. 58-501855: Patent Document 5), and US Pat. No. 4,465,488. (See Patent Document 6), US Pat. No. 5,431,496 (Japanese Patent Publication No. 7-505080: see Patent Document 7), and the like.
U.S. Pat. No. 4,458,811 US Pat. No. 4,608,043 US Pat. No. 5,577,369 JP-A-57-52455 US Pat. No. 4,396,383 U.S. Pat. No. 4,465,488 US Pat. No. 5,431,496

However, in the liquid container described above, if the delivery port is opened before the drug is sufficiently mixed in the process of mixing two liquids, only one component of the drug will be injected into the body. Could happen.

In addition, when incinerated in a mixed state with a polymer material containing a benzene ring in disposal after use of a liquid container made of a polymer material, organic chlorine compounds are discharged, causing an increase in environmental impact. Furthermore, it has become a cause of high cost in the manufacturing process. Furthermore, in the case of a vinyl chloride material, there has been a problem in that elution of additives such as phthalate ester occurs when the state of the polymer is changed by high-temperature steam sterilization, ultraviolet irradiation, or the like in the manufacturing process.

Therefore, the liquid container according to the present invention includes a plurality of solution storage compartments and a mixing compartment provided adjacent to the solution storage compartment, and the solution storage compartment and the mixing compartment are partitioned by a sealing means, An object of the present invention is to provide a novel liquid container that can be safely and sufficiently mixed in an aseptic state when mixing each liquid agent by opening the sealing means by an external pulling force.

In order to solve the above-described problems, a liquid container according to the present invention includes a plurality of solution storage compartments for storing a solution in a sealed manner, and a mixing compartment adjacent to the solution storage compartment for mixing a plurality of solutions. Because
The solution storage section and the mixing section are partitioned by a sealing means that can be opened by an external force.
By doing so, it is possible to open the sealing means that can be opened by external force as necessary, to feed the solutions in the plurality of solution storage compartments into the mixing compartment, and to mix each solution in the mixing compartment. (Claim 1).

In the liquid container according to the present invention, the mixing compartment is provided with a delivery outlet for sending the mixed solution to the outside, and the solution mixed in the mixing compartment is delivered from the delivery outlet ( Claim 2).

In the liquid container according to the present invention, the external force is a tension in the outward direction, and the solution can be mixed in the mixing compartment by opening the sealing means that can be opened by the external force as necessary. (Claim 3).

In the liquid container according to the present invention, the sealing means is configured such that a protruding strip portion and a recessed groove portion that are arranged to face the inner surface of the container are detachably fitted.

In the liquid container according to the present invention, a plurality of opening means that can be opened simultaneously are provided in the sealing means.

According to the present invention, since the procedure for mixing a plurality of liquids constituting the dialysate is clear, it is possible to prevent medical accidents caused by liquid mixing failure. In addition, since it is not necessary to develop a sealing means having a multi-stage open pressure threshold, the manufacturing process is simplified, and it becomes possible to form the entire container with a single material made of elastomers with different molded shapes, Therefore, it is possible to provide a medical device made of a low environmental load material that is free from the concern of causing pollution due to disposal.

FIG. 1 is a perspective view before completion of the assembly of the liquid container 1 according to the present invention. The illustrated liquid container 1 includes a container body 10, a sealing means 20, an inlet 30, and an outlet 40. The container main body 10 has a cylindrical shape, and has two sealing means 20 formed along the length direction inside. The inlet 30 and the outlet 40 can be attached by thermal fusion when closing the openings 11 and 12 of the cylindrical container body 10. The material of the container body 10 is a polymer sheet, and the material of the inlet 30 and the outlet 40 is a soft elastomer.

FIG. 2A is a perspective view after the assembly of the liquid container 1 shown in FIG. 1 is completed. The illustrated liquid container 1 includes a container body 10, a sealing means 20, an inlet 30, and an outlet 40. The container main body 10 has two sealing means 20 formed along the length direction inside. By closing the sealing means 20, the inside of the cylindrical container body 10 is divided into three sections A, B, and C. In FIG. 1, sections A and C are solution storage sections, and section B is a mixing section. Reference numeral 25 denotes an opening means by an external force of the sealing means 20, which indicates a sheet-like fusion piece having one end fused to the two sealing means 20 and the other end being a free end. It is possible to apply a force by pinching 25 and pulling from the outside. Of course, as long as it is an opening means by the external force of the sealing means 20, not only a sheet-like fusion piece but also various knob pieces, hooks, finger-holding structures and the like can be adopted.
And when closing the opening parts 11 and 12 of the cylindrical container main body 10 shown in FIG. 1, the inlet 30 is attached to the welding part 13 of the solution storage section A and the solution storage section C in the opening part 11 by thermal fusion. The outlet 40 is attached to the welding portion 14 of the mixing section B at the opening 12 by heat sealing. With such a structure, the liquid can be stored in the solution storage section A and the solution storage section C from the inlet 30.
Then, when the sealing means 20 is opened by a predetermined pulling force by operating the opening means 25 as shown in FIG. 2B, the liquid stored in the solution storage section A and the solution storage section C is mixed with the mixing section B. And mixed safely in an aseptic state without being contaminated in the mixing section B, and the liquid mixture can be delivered from the outlet 40 attached to the mixing section B.
In addition, since the internal pressure of the container main body 10 decreases by opening the sealing means 20, the pressure applied to the delivery port 40 is reduced. Therefore, it is possible to prevent a medical error / accident caused by the liquid breaking the valve of the delivery port 40 and flowing out when the mixing is not completed.

3 is a cross-sectional view of the sealing means 20 shown in FIG. The illustrated sealing means 20 is a chuck composed of a concave groove portion 21 and a convex strip portion 22 respectively formed on opposing inner side surfaces of the container main body 10 and brought into close contact with each other by meshing with each other. The sealing means 20 can be easily opened and closed by a predetermined pressure and pulling force.

FIG. 4 is a perspective view showing a state in which the liquid container 1 according to the present invention is folded in two with the solution stored in the solution storage section A and the solution storage section C. In the illustrated liquid container 1, the delivery port 40 attached to the end of the container body 10 is folded along the mixing section B of the container body 10, and the solution storage section A and the solution storage section C are further connected to the delivery port. The side 15 of the solution storage section A and the side 16 of the solution storage section C are connected and fixed by a seal 50.
Further, in order to unfold the folded state, a traction string 51 having one end connected to the sealing means 20 and an intermediate portion attached to the seal 50 is provided.
The liquid container 1 is transported in the folded state as described above.

FIG. 5 is a perspective view showing a state of the liquid container 1 shown in FIG. 4 at the time of liquid mixing. When the traction string 51 is pulled in the folded liquid container 1 of FIG. 4, the seal 50 is shaken and folded along the solution storage section A, the solution storage section C, and the mixing section B as shown in FIG. The exit 40 which has been opened is developed. Here, when the tow string 51 is further pulled, a part of the sealing means 20 connected to the tow string 51 is opened, and the liquid stored in the solution storage section A and the solution storage section C is aseptically stored in the mixing section B. Inflow. In this case, the tow string 51 also serves as a means for opening the sealing means 20.
In this state, after the liquid is sufficiently mixed in the mixing section B by alternately applying pressure to the solution storage section A and the solution storage section C, the stopper 41 and the pinch cock 42 provided at the delivery port 40 are removed. Allow the liquid to drain.
It should be noted that the pinch cock 42 is used as an example, and any other method will not cause any problem as long as the structure can control the flow of the liquid. Moreover, since the sterility of the liquid container 1 is maintained by the stopper 41, the liquid can be mixed and transported in a sterile state.

FIG. 6 is a perspective view showing a multi-compartment state of the liquid container 1 according to the present invention. The illustrated liquid container 1 includes a container body 10, a sealing means 20, an injection port 30, a delivery port 40, and a heat fusion part 60. The container main body 10 has two sealing means 20 formed along the length direction inside. By closing both of the sealing means 20, the inside of the container body 1 is divided into a solution storage section A, a solution storage section C, and a mixing section B. At this time, the solution storage section C can be divided into the solution storage section D and the solution storage section E by newly providing the heat fusion part 60 in the intermediate part of the solution storage section C. In order to mix the solutions in the solution storage section A, the solution storage section D, and the solution storage section E, it is only necessary to open both of the sealing means 20.
If it does in this way, expansion of a solution storage section will be attained if needed. Therefore, it is possible to store various kinds of liquids and mix them in aseptic conditions.

The present invention can provide a liquid container used for mixing a plurality of drug solutions such as dialysate used for peritoneal dialysis.

It is a perspective view before the completion of the assembly of the liquid container according to the present invention. (A) is a perspective view after completion of the assembly of the liquid container shown in FIG. 1, (b) is a schematic cross-sectional view in the case of performing an opening operation. It is sectional drawing at the time of opening / closing operation | movement of the sealing means shown in FIG. It is a perspective view which shows the state by which the liquid container which concerns on this invention was folded. It is a perspective view which shows the state at the time of liquid mixing of the liquid container shown in FIG. It is a perspective view which shows the multi-compartment state of the liquid container which concerns on this invention.

Explanation of symbols

DESCRIPTION OF SYMBOLS 1 Liquid container 10 Container main body 11 Opening part 12 Opening part 13 Welding part 14 Welding part 15 Side part 16 of division A Side part 20 of division C Sealing means 21 Groove part 22 Convex part 25 Opening means 30 Inlet 40 Outlet 41 Plug 42 Pinch cock 50 Seal 51 Tow string 60 Heat fusion part A Solution storage section B Mixing section C Solution storage section D Solution storage section E Solution storage section

Claims (5)

A liquid container having a plurality of solution storage compartments for storing a solution hermetically, and a mixing compartment adjacent to the solution storage compartment for mixing a plurality of solutions,
The liquid container, wherein the solution storage section and the mixing section are partitioned by a sealing means that can be opened by an external force. The liquid container according to claim 1, wherein the mixing section is provided with a delivery port for sending the mixed solution to the outside. The liquid container according to claim 1, wherein the external force is a tension in an outward direction. The liquid container according to any one of claims 1 to 3, wherein the sealing means has a configuration in which a ridge portion and a groove portion that are arranged to face the inner surface of the container are detachably fitted. The liquid container according to claim 1, wherein a plurality of opening means that can be opened simultaneously are provided in the sealing means.

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