JP2007535930A5 - - Google Patents
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- JP2007535930A5 JP2007535930A5 JP2007511437A JP2007511437A JP2007535930A5 JP 2007535930 A5 JP2007535930 A5 JP 2007535930A5 JP 2007511437 A JP2007511437 A JP 2007511437A JP 2007511437 A JP2007511437 A JP 2007511437A JP 2007535930 A5 JP2007535930 A5 JP 2007535930A5
- Authority
- JP
- Japan
- Prior art keywords
- skin
- subject
- expression
- antagonist
- level
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 238000000034 method Methods 0.000 claims 12
- 102000013691 Interleukin-17 Human genes 0.000 claims 11
- 201000004624 Dermatitis Diseases 0.000 claims 9
- 239000005557 antagonist Substances 0.000 claims 6
- 201000004681 Psoriasis Diseases 0.000 claims 4
- 230000037311 normal skin Effects 0.000 claims 4
- 230000002757 inflammatory effect Effects 0.000 claims 3
- 208000017520 skin disease Diseases 0.000 claims 3
- 230000001747 exhibiting effect Effects 0.000 claims 2
- 230000001185 psoriatic effect Effects 0.000 claims 2
- 238000003753 real-time PCR Methods 0.000 claims 2
- 108020004459 Small interfering RNA Proteins 0.000 claims 1
- 239000012634 fragment Substances 0.000 claims 1
- 239000003112 inhibitor Substances 0.000 claims 1
- 230000003902 lesion Effects 0.000 claims 1
- 108020004999 messenger RNA Proteins 0.000 claims 1
- 150000003384 small molecules Chemical class 0.000 claims 1
- 208000024891 symptom Diseases 0.000 claims 1
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US56774704P | 2004-05-03 | 2004-05-03 | |
| PCT/US2005/014720 WO2005108616A1 (en) | 2004-05-03 | 2005-05-02 | Use of il-17 expression to predict skin inflammation; methods of treatment |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2007535930A JP2007535930A (ja) | 2007-12-13 |
| JP2007535930A5 true JP2007535930A5 (enExample) | 2008-06-19 |
Family
ID=34967584
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2007511437A Pending JP2007535930A (ja) | 2004-05-03 | 2005-05-02 | 皮膚の炎症を予測するためのil−17発現の使用;処置方法 |
Country Status (11)
| Country | Link |
|---|---|
| US (2) | US7501247B2 (enExample) |
| EP (1) | EP1761643A1 (enExample) |
| JP (1) | JP2007535930A (enExample) |
| CN (1) | CN1993480A (enExample) |
| AU (1) | AU2005241020B2 (enExample) |
| BR (1) | BRPI0510617A (enExample) |
| CA (1) | CA2565566A1 (enExample) |
| MX (1) | MXPA06012754A (enExample) |
| NO (1) | NO20065560L (enExample) |
| WO (1) | WO2005108616A1 (enExample) |
| ZA (1) | ZA200609140B (enExample) |
Families Citing this family (45)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7422743B2 (en) * | 2000-05-10 | 2008-09-09 | Schering Corporation | Mammalian receptor protein DCRS5;methods of treatment |
| US20070160576A1 (en) * | 2001-06-05 | 2007-07-12 | Genentech, Inc. | IL-17A/F heterologous polypeptides and therapeutic uses thereof |
| DK1576011T3 (da) | 2002-10-30 | 2009-11-30 | Genentech Inc | Inhibering af IL-17 produktion |
| US7247711B2 (en) * | 2003-05-09 | 2007-07-24 | Centocor, Inc. | IL-23p40 specific antibody |
| BRPI0510617A (pt) * | 2004-05-03 | 2007-10-30 | Schering Corp | uso de expressão de il-17 para prever inflamação de pele; processos de tratamento |
| GB0417487D0 (en) | 2004-08-05 | 2004-09-08 | Novartis Ag | Organic compound |
| AR051444A1 (es) * | 2004-09-24 | 2007-01-17 | Centocor Inc | Proteinas derivadas de inmunoglobulina especifica de il-23p40, composiciones, epitopos, metodos y usos |
| US10080779B2 (en) | 2004-12-15 | 2018-09-25 | Universite D'angers | Method for increasing the expression of anti-microbial peptides by keratinocytes comprising administering a composition comprising IL-17, TNF-alpha and OSM |
| EP1671642A1 (en) * | 2004-12-15 | 2006-06-21 | Universite D'angers | Compositions comprising (ant)agonists of oncostatin M (OSM), IL-31 and IFN-gamma for modulating keratinocyte migration and functions via a receptor containing OSMRbeta as a subunit, and applications thereof. |
| US7704503B2 (en) * | 2005-02-14 | 2010-04-27 | Wyeth Llc | Use of IL-17F in diagnosis and therapy of airway inflammation |
| PT1896073E (pt) | 2005-06-30 | 2013-05-28 | Janssen Biotech Inc | Composições, métodos e aplicações de anticorpos anti-il-23 |
| CN101296706B (zh) * | 2005-09-01 | 2011-11-30 | 先灵公司 | Il-23和il-17拮抗剂治疗自身免疫性眼部炎性疾病的用途 |
| AU2006330411B2 (en) | 2005-12-29 | 2012-07-12 | Janssen Biotech, Inc. | Human anti-IL-23 antibodies, compositions, methods and uses |
| US7910703B2 (en) | 2006-03-10 | 2011-03-22 | Zymogenetics, Inc. | Antagonists to IL-17A, IL-17F, and IL-23P19 and methods of use |
| WO2007147019A2 (en) | 2006-06-13 | 2007-12-21 | Zymogenetics, Inc. | Il-17 and il-23 antagonists and methods of using the same |
| AU2007261019A1 (en) * | 2006-06-19 | 2007-12-27 | Wyeth | Methods of modulating IL-22 and IL-17 |
| US7846443B2 (en) | 2006-08-11 | 2010-12-07 | Schering Corporation | Antibodies to IL-17A |
| EP2417974A1 (en) * | 2007-02-28 | 2012-02-15 | Schering Corporation | Combination therapy for treatment of immune disorders |
| WO2008134659A2 (en) * | 2007-04-27 | 2008-11-06 | Zymogenetics, Inc. | Antagonists to il-17a, il-17f, and il-23p19 and methods of use |
| WO2009082624A2 (en) * | 2007-12-10 | 2009-07-02 | Zymogenetics, Inc. | Antagonists of il-17a, il-17f, and il-23 and methods of using the same |
| KR20170023209A (ko) | 2008-05-05 | 2017-03-02 | 노비뮨 에스 에이 | 항-il-17a/il-17f 교차-반응성 항체 및 그의 사용 방법 |
| EP2294216A4 (en) | 2008-05-14 | 2011-11-23 | Dermtech Int | DIAGNOSIS OF MELANOMA AND SOLAR LENTIGO BY ANALYSIS OF NUCLEIC ACIDS |
| US20100233270A1 (en) | 2009-01-08 | 2010-09-16 | Northwestern University | Delivery of Oligonucleotide-Functionalized Nanoparticles |
| CN108451968A (zh) * | 2009-04-15 | 2018-08-28 | 西北大学 | 寡核苷酸功能化的纳米颗粒的递送 |
| PE20120815A1 (es) | 2009-05-05 | 2012-07-08 | Novimmune Sa | Anticuerpos anti il-17f y metodos de uso de los mismos |
| JO3244B1 (ar) | 2009-10-26 | 2018-03-08 | Amgen Inc | بروتينات ربط مستضادات il – 23 البشرية |
| AU2010313304B2 (en) | 2009-10-30 | 2015-08-20 | Janssen Biotech, Inc. | IL-17A antagonists |
| WO2012061448A1 (en) | 2010-11-04 | 2012-05-10 | Boehringer Ingelheim International Gmbh | Anti-il-23 antibodies |
| JP6279467B2 (ja) * | 2011-06-27 | 2018-02-14 | ガルデルマ・リサーチ・アンド・デヴェロップメント | ざ瘡についての新規th17分化マーカーおよびその使用 |
| EP2809660B1 (en) | 2012-02-02 | 2016-01-20 | Ensemble Therapeutics Corporation | Macrocyclic compounds for modulating il-17 |
| US11078265B2 (en) | 2012-05-03 | 2021-08-03 | Boehringer Ingelheim International Gmbh | Anti-IL-23 antibodies |
| CN104884473B (zh) | 2012-05-22 | 2019-12-03 | 百时美施贵宝公司 | Il-17a/f il-23双特异性抗体及其应用 |
| WO2016014775A1 (en) | 2014-07-24 | 2016-01-28 | Boehringer Ingelheim International Gmbh | Biomarkers useful in the treatment of il-23a related diseases |
| WO2016036918A1 (en) | 2014-09-03 | 2016-03-10 | Boehringer Ingelheim International Gmbh | Compound targeting il-23a and tnf-alpha and uses thereof |
| BR112017014684A2 (en) | 2015-02-04 | 2018-01-09 | Boehringer Ingelheim International Gmbh | methods of treatment of inflammatory diseases |
| JP2018521047A (ja) * | 2015-07-16 | 2018-08-02 | イーライ リリー アンド カンパニー | 掻痒の治療 |
| RU2680011C2 (ru) | 2016-04-29 | 2019-02-14 | Закрытое Акционерное Общество "Биокад" | Триспецифические антитела против il-17a, il-17f и другой провоспалительной молекулы |
| KR102617833B1 (ko) | 2016-05-06 | 2023-12-27 | 엑시큐어 오퍼레이팅 컴퍼니 | 인터류킨 17 수용체 mRNA의 특이적 녹다운을 위한 안티센스 올리고뉴클레오티드 (ASO)를 제시하는 리포좀성 구형 핵산 (SNA) 구축물 |
| WO2018209270A1 (en) | 2017-05-11 | 2018-11-15 | Northwestern University | Adoptive cell therapy using spherical nucleic acids (snas) |
| US11976332B2 (en) | 2018-02-14 | 2024-05-07 | Dermtech, Inc. | Gene classifiers and uses thereof in non-melanoma skin cancers |
| CA3092551A1 (en) | 2018-03-05 | 2019-09-12 | Janssen Biotech, Inc. | Methods of treating crohn's disease with anti-il23 specific antibody |
| AU2019266226A1 (en) | 2018-05-09 | 2020-12-03 | Dermtech, Inc. | Novel gene classifiers and uses thereof in autoimmune diseases |
| BR112021009287A2 (pt) | 2018-11-20 | 2021-10-26 | Janssen Biotech, Inc. | Método seguro e eficaz para tratar psoríase com anticorpo específico anti-il-23 |
| CA3138241A1 (en) | 2019-05-23 | 2020-11-26 | Janssen Biotech, Inc. | Method of treating inflammatory bowel disease with a combination therapy of antibodies to il-23 and tnf alpha |
| EP4596046A3 (en) | 2020-05-21 | 2025-10-22 | Janssen Biotech, Inc. | Method of treating inflammatory bowel disease with a combination therapy of antibodies to il-23 and tnf alpha |
Family Cites Families (19)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2001046420A2 (en) * | 1999-12-23 | 2001-06-28 | Genentech, Inc. | Il-17 and il-17r homologous polypeptides and therapeutic uses thereof |
| US6482923B1 (en) * | 1997-09-17 | 2002-11-19 | Human Genome Sciences, Inc. | Interleukin 17-like receptor protein |
| NZ508878A (en) * | 1998-05-15 | 2003-08-29 | Genentech Inc | IL-17B and IL-17Cactive variants of IL-17 which stimulates epithelial, endothelial and fibroblastic cells |
| US20030083231A1 (en) | 1998-11-24 | 2003-05-01 | Ahlem Clarence N. | Blood cell deficiency treatment method |
| US6914128B1 (en) * | 1999-03-25 | 2005-07-05 | Abbott Gmbh & Co. Kg | Human antibodies that bind human IL-12 and methods for producing |
| US7090847B1 (en) | 1999-09-09 | 2006-08-15 | Schering Corporation | Mammalian cytokines; related reagents and methods |
| JP2003527104A (ja) * | 1999-12-23 | 2003-09-16 | ジェネンテック・インコーポレーテッド | Il−17相同的ポリペプチドとその治療上の用途 |
| EP1287130B2 (en) * | 2000-05-10 | 2017-07-26 | Merck Sharp & Dohme Corp. | Mammalian cytokine receptor subunit proteins, related reagents and methods |
| AU2002326285A1 (en) * | 2001-01-25 | 2003-01-02 | Zymogenetics, Inc. | Method for treating psoriasis by using an il-17d antagonist |
| CA2442134A1 (en) * | 2001-03-29 | 2002-10-10 | Celltech R & D, Inc. | Compositions and methods for diagnosing or treating psoriasis |
| DK1576011T3 (da) * | 2002-10-30 | 2009-11-30 | Genentech Inc | Inhibering af IL-17 produktion |
| WO2004058178A2 (en) * | 2002-12-23 | 2004-07-15 | Schering Corporation | Uses of mammalian cytokine; related reagents |
| DE60336930D1 (de) | 2002-12-31 | 2011-06-09 | Schering Corp | IL-27 et IL-2 pour le traitement du cancer |
| US7247711B2 (en) * | 2003-05-09 | 2007-07-24 | Centocor, Inc. | IL-23p40 specific antibody |
| EP1641822B1 (en) | 2003-07-08 | 2013-05-15 | Genentech, Inc. | Il-17 a/f heterologous polypeptides and therapeutic uses thereof |
| US7501427B2 (en) * | 2003-08-14 | 2009-03-10 | Array Biopharma, Inc. | Quinazoline analogs as receptor tyrosine kinase inhibitors |
| US7183057B2 (en) | 2004-03-31 | 2007-02-27 | Dermtech International | Tape stripping methods for analysis of skin disease and pathological skin state |
| US20050287593A1 (en) * | 2004-05-03 | 2005-12-29 | Schering Corporation | Use of cytokine expression to predict skin inflammation; methods of treatment |
| BRPI0510617A (pt) * | 2004-05-03 | 2007-10-30 | Schering Corp | uso de expressão de il-17 para prever inflamação de pele; processos de tratamento |
-
2005
- 2005-05-02 BR BRPI0510617-6A patent/BRPI0510617A/pt not_active IP Right Cessation
- 2005-05-02 WO PCT/US2005/014720 patent/WO2005108616A1/en not_active Ceased
- 2005-05-02 US US11/120,518 patent/US7501247B2/en active Active
- 2005-05-02 MX MXPA06012754A patent/MXPA06012754A/es unknown
- 2005-05-02 CA CA002565566A patent/CA2565566A1/en not_active Abandoned
- 2005-05-02 JP JP2007511437A patent/JP2007535930A/ja active Pending
- 2005-05-02 EP EP05741769A patent/EP1761643A1/en not_active Withdrawn
- 2005-05-02 AU AU2005241020A patent/AU2005241020B2/en not_active Ceased
- 2005-05-02 CN CNA2005800224849A patent/CN1993480A/zh active Pending
-
2006
- 2006-11-02 ZA ZA200609140A patent/ZA200609140B/xx unknown
- 2006-12-01 NO NO20065560A patent/NO20065560L/no unknown
-
2008
- 2008-09-02 US US12/202,935 patent/US7776540B2/en not_active Expired - Lifetime
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