JP2007530226A5 - - Google Patents
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- Publication number
- JP2007530226A5 JP2007530226A5 JP2007506237A JP2007506237A JP2007530226A5 JP 2007530226 A5 JP2007530226 A5 JP 2007530226A5 JP 2007506237 A JP2007506237 A JP 2007506237A JP 2007506237 A JP2007506237 A JP 2007506237A JP 2007530226 A5 JP2007530226 A5 JP 2007530226A5
- Authority
- JP
- Japan
- Prior art keywords
- composition
- viscoelastic
- maximum
- minimum
- composition according
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 239000000203 mixture Substances 0.000 claims 46
- 229920000642 polymer Polymers 0.000 claims 7
- 229920005862 polyol Polymers 0.000 claims 7
- 150000003077 polyols Chemical class 0.000 claims 7
- FHVDTGUDJYJELY-UHFFFAOYSA-N 6-{[2-carboxy-4,5-dihydroxy-6-(phosphanyloxy)oxan-3-yl]oxy}-4,5-dihydroxy-3-phosphanyloxane-2-carboxylic acid Chemical compound O1C(C(O)=O)C(P)C(O)C(O)C1OC1C(C(O)=O)OC(OP)C(O)C1O FHVDTGUDJYJELY-UHFFFAOYSA-N 0.000 claims 6
- 229940072056 alginate Drugs 0.000 claims 6
- 235000010443 alginic acid Nutrition 0.000 claims 6
- 229920000615 alginic acid Polymers 0.000 claims 6
- KIUKXJAPPMFGSW-DNGZLQJQSA-N (2S,3S,4S,5R,6R)-6-[(2S,3R,4R,5S,6R)-3-Acetamido-2-[(2S,3S,4R,5R,6R)-6-[(2R,3R,4R,5S,6R)-3-acetamido-2,5-dihydroxy-6-(hydroxymethyl)oxan-4-yl]oxy-2-carboxy-4,5-dihydroxyoxan-3-yl]oxy-5-hydroxy-6-(hydroxymethyl)oxan-4-yl]oxy-3,4,5-trihydroxyoxane-2-carboxylic acid Chemical group CC(=O)N[C@H]1[C@H](O)O[C@H](CO)[C@@H](O)[C@@H]1O[C@H]1[C@H](O)[C@@H](O)[C@H](O[C@H]2[C@@H]([C@@H](O[C@H]3[C@@H]([C@@H](O)[C@H](O)[C@H](O3)C(O)=O)O)[C@H](O)[C@@H](CO)O2)NC(C)=O)[C@@H](C(O)=O)O1 KIUKXJAPPMFGSW-DNGZLQJQSA-N 0.000 claims 5
- 229920002674 hyaluronan Polymers 0.000 claims 5
- 229960003160 hyaluronic acid Drugs 0.000 claims 5
- 239000001866 hydroxypropyl methyl cellulose Substances 0.000 claims 5
- 229920003088 hydroxypropyl methyl cellulose Polymers 0.000 claims 5
- 235000010979 hydroxypropyl methyl cellulose Nutrition 0.000 claims 5
- UFVKGYZPFZQRLF-UHFFFAOYSA-N hydroxypropyl methyl cellulose Chemical compound OC1C(O)C(OC)OC(CO)C1OC1C(O)C(O)C(OC2C(C(O)C(OC3C(C(O)C(O)C(CO)O3)O)C(CO)O2)O)C(CO)O1 UFVKGYZPFZQRLF-UHFFFAOYSA-N 0.000 claims 5
- 150000003839 salts Chemical class 0.000 claims 5
- LENZDBCJOHFCAS-UHFFFAOYSA-N tris Chemical compound OCC(N)(CO)CO LENZDBCJOHFCAS-UHFFFAOYSA-N 0.000 claims 4
- 150000001298 alcohols Chemical class 0.000 claims 3
- SQDAZGGFXASXDW-UHFFFAOYSA-N 5-bromo-2-(trifluoromethoxy)pyridine Chemical compound FC(F)(F)OC1=CC=C(Br)C=N1 SQDAZGGFXASXDW-UHFFFAOYSA-N 0.000 claims 2
- 229920002134 Carboxymethyl cellulose Polymers 0.000 claims 2
- 229920001287 Chondroitin sulfate Polymers 0.000 claims 2
- 102000008186 Collagen Human genes 0.000 claims 2
- 108010035532 Collagen Proteins 0.000 claims 2
- 229920002307 Dextran Polymers 0.000 claims 2
- 239000001856 Ethyl cellulose Substances 0.000 claims 2
- ZZSNKZQZMQGXPY-UHFFFAOYSA-N Ethyl cellulose Chemical compound CCOCC1OC(OC)C(OCC)C(OCC)C1OC1C(O)C(O)C(OC)C(CO)O1 ZZSNKZQZMQGXPY-UHFFFAOYSA-N 0.000 claims 2
- 229920000663 Hydroxyethyl cellulose Polymers 0.000 claims 2
- 239000004354 Hydroxyethyl cellulose Substances 0.000 claims 2
- 229920002153 Hydroxypropyl cellulose Polymers 0.000 claims 2
- 229920002125 Sokalan® Polymers 0.000 claims 2
- 239000001768 carboxy methyl cellulose Substances 0.000 claims 2
- 235000010948 carboxy methyl cellulose Nutrition 0.000 claims 2
- 239000008112 carboxymethyl-cellulose Substances 0.000 claims 2
- 229940059329 chondroitin sulfate Drugs 0.000 claims 2
- 229920001436 collagen Polymers 0.000 claims 2
- 229920001249 ethyl cellulose Polymers 0.000 claims 2
- 235000019325 ethyl cellulose Nutrition 0.000 claims 2
- 150000004676 glycans Chemical class 0.000 claims 2
- 235000019447 hydroxyethyl cellulose Nutrition 0.000 claims 2
- 239000001863 hydroxypropyl cellulose Substances 0.000 claims 2
- 235000010977 hydroxypropyl cellulose Nutrition 0.000 claims 2
- 229920000609 methyl cellulose Polymers 0.000 claims 2
- 239000001923 methylcellulose Substances 0.000 claims 2
- 235000010981 methylcellulose Nutrition 0.000 claims 2
- 229920001277 pectin Polymers 0.000 claims 2
- 239000001814 pectin Substances 0.000 claims 2
- 235000010987 pectin Nutrition 0.000 claims 2
- 229920001282 polysaccharide Polymers 0.000 claims 2
- 239000005017 polysaccharide Substances 0.000 claims 2
- 229920000036 polyvinylpyrrolidone Polymers 0.000 claims 2
- 239000001267 polyvinylpyrrolidone Substances 0.000 claims 2
- 235000013855 polyvinylpyrrolidone Nutrition 0.000 claims 2
- LNAZSHAWQACDHT-XIYTZBAFSA-N (2r,3r,4s,5r,6s)-4,5-dimethoxy-2-(methoxymethyl)-3-[(2s,3r,4s,5r,6r)-3,4,5-trimethoxy-6-(methoxymethyl)oxan-2-yl]oxy-6-[(2r,3r,4s,5r,6r)-4,5,6-trimethoxy-2-(methoxymethyl)oxan-3-yl]oxyoxane Chemical compound CO[C@@H]1[C@@H](OC)[C@H](OC)[C@@H](COC)O[C@H]1O[C@H]1[C@H](OC)[C@@H](OC)[C@H](O[C@H]2[C@@H]([C@@H](OC)[C@H](OC)O[C@@H]2COC)OC)O[C@@H]1COC LNAZSHAWQACDHT-XIYTZBAFSA-N 0.000 claims 1
- FBPFZTCFMRRESA-FSIIMWSLSA-N D-Glucitol Natural products OC[C@H](O)[C@H](O)[C@@H](O)[C@H](O)CO FBPFZTCFMRRESA-FSIIMWSLSA-N 0.000 claims 1
- FBPFZTCFMRRESA-KVTDHHQDSA-N D-Mannitol Chemical compound OC[C@@H](O)[C@@H](O)[C@H](O)[C@H](O)CO FBPFZTCFMRRESA-KVTDHHQDSA-N 0.000 claims 1
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 claims 1
- 102000011782 Keratins Human genes 0.000 claims 1
- 108010076876 Keratins Proteins 0.000 claims 1
- 229930195725 Mannitol Natural products 0.000 claims 1
- 229920003171 Poly (ethylene oxide) Polymers 0.000 claims 1
- 229920000148 Polycarbophil calcium Polymers 0.000 claims 1
- 239000004372 Polyvinyl alcohol Substances 0.000 claims 1
- 102000016611 Proteoglycans Human genes 0.000 claims 1
- 108010067787 Proteoglycans Proteins 0.000 claims 1
- 239000007864 aqueous solution Substances 0.000 claims 1
- 229920001525 carrageenan Polymers 0.000 claims 1
- 235000010418 carrageenan Nutrition 0.000 claims 1
- 230000000052 comparative effect Effects 0.000 claims 1
- 230000002779 inactivation Effects 0.000 claims 1
- 239000000594 mannitol Substances 0.000 claims 1
- 235000010355 mannitol Nutrition 0.000 claims 1
- 229960000292 pectin Drugs 0.000 claims 1
- 239000004584 polyacrylic acid Substances 0.000 claims 1
- 229950005134 polycarbophil Drugs 0.000 claims 1
- -1 polyoxyethylenes Polymers 0.000 claims 1
- 229920002451 polyvinyl alcohol Polymers 0.000 claims 1
- 239000000600 sorbitol Substances 0.000 claims 1
- 239000000230 xanthan gum Substances 0.000 claims 1
- 235000010493 xanthan gum Nutrition 0.000 claims 1
- 229920001285 xanthan gum Polymers 0.000 claims 1
- 229940082509 xanthan gum Drugs 0.000 claims 1
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US10/812,551 US20050215516A1 (en) | 2004-03-29 | 2004-03-29 | New free-radical scavenger containing viscoelastic composition, methods of use and package |
| PCT/US2005/009512 WO2005097226A1 (en) | 2004-03-29 | 2005-03-22 | New free-radical scavenger containing viscoelastic composition, methods of use and package |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2007530226A JP2007530226A (ja) | 2007-11-01 |
| JP2007530226A5 true JP2007530226A5 (https=) | 2008-05-08 |
Family
ID=34963427
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2007506237A Pending JP2007530226A (ja) | 2004-03-29 | 2005-03-22 | 遊離基スカベンジャーを含有する新しい粘弾性組成物及びその使用方法とパッケージ |
Country Status (11)
| Country | Link |
|---|---|
| US (2) | US20050215516A1 (https=) |
| EP (1) | EP1732620B1 (https=) |
| JP (1) | JP2007530226A (https=) |
| KR (1) | KR20060131938A (https=) |
| CN (2) | CN101485906A (https=) |
| AT (1) | ATE401915T1 (https=) |
| AU (1) | AU2005231687B2 (https=) |
| CA (1) | CA2560943C (https=) |
| DE (1) | DE602005008413D1 (https=) |
| ES (1) | ES2309735T3 (https=) |
| WO (1) | WO2005097226A1 (https=) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2918276B1 (fr) | 2007-07-02 | 2010-01-22 | Anteis Sa | "utilisation d'un gel de polysaccharide(s)naturel(s)pour la preparation d'une formulation injectable de traitement des degenerescences articulaires" |
| US10028976B2 (en) | 2007-07-02 | 2018-07-24 | Aptissen Sa | Injectable formulation of natural polysaccharide and polyol for treatment of osteoarthritis |
| GB2501943B (en) * | 2012-05-10 | 2020-09-23 | Zeiss Carl Meditec Ag | Ophthalmic viscoelastic device |
| AT514540A1 (de) | 2013-06-18 | 2015-01-15 | Apomedica Pharmazeutische Produkte Gmbh | Ophthalmische Zusammensetzung |
| PL3193832T3 (pl) * | 2015-06-17 | 2019-12-31 | Al.Chi.Mi.A. S.R.L. | Lepkosprężysty preparat do stosowania w metodach chirurgicznych w chirurgii ocznej |
| WO2017131130A1 (ja) * | 2016-01-29 | 2017-08-03 | 生化学工業株式会社 | コンドロイチン硫酸及びヒアルロン酸を含有する安定化された水性組成物 |
| EP3713617A1 (en) * | 2017-11-22 | 2020-09-30 | Bausch & Lomb Incorporated | Ophthalmic viscoelastic compositions |
| CN108371729A (zh) * | 2018-05-22 | 2018-08-07 | 上海建华精细生物制品有限公司 | 有自由基清除功能的眼科手术粘弹剂及其制备方法和应用 |
| WO2020005416A1 (en) | 2018-06-27 | 2020-01-02 | Bausch & Lomb Incorporated | Packaging solutions |
Family Cites Families (30)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| NL145136C (https=) * | 1967-07-25 | 1900-01-01 | ||
| US3693613A (en) * | 1970-12-09 | 1972-09-26 | Cavitron Corp | Surgical handpiece and flow control system for use therewith |
| US4287175A (en) * | 1978-06-22 | 1981-09-01 | Merck & Co., Inc. | Contact lens wetting agents |
| US4713375A (en) * | 1985-08-01 | 1987-12-15 | Lindstrom Richard L | Viscoelastic solution |
| CA1284250C (en) * | 1985-09-06 | 1991-05-14 | Dale P. Devore | Viscoelastic collagen solution for ophthalmic use and method of preparation |
| US4819617A (en) * | 1986-09-04 | 1989-04-11 | University Of Florida | Viscoelastic material for ophthalmic surgery |
| JPS6419024A (en) * | 1987-07-15 | 1989-01-23 | Tosoh Corp | Separation of immunoglobulin g subclass |
| US5597599A (en) * | 1987-09-08 | 1997-01-28 | Pakor, Inc. | Method for processing a perishable product |
| US5252557A (en) * | 1988-07-25 | 1993-10-12 | Kiyoshi Kita | Administration method of antithrombin |
| US5013714A (en) * | 1988-12-15 | 1991-05-07 | Lindstrom Richard L | Viscoelastic solution |
| US5204325A (en) * | 1988-12-15 | 1993-04-20 | Lindstrom Richard L | Viscoelastic solution |
| US5102653A (en) * | 1990-01-11 | 1992-04-07 | Skelnik Debra L | Non-primate vitreal replacement model |
| US5104787A (en) * | 1990-03-05 | 1992-04-14 | Lindstrom Richard L | Method for apparatus for a defined serumfree medical solution useful for corneal preservation |
| EP0464727B1 (en) * | 1990-06-29 | 1996-01-03 | Santen Pharmaceutical Co., Ltd. | Use of a composition for the preparation of a medicament for debridment of retained lens material |
| CA2086014A1 (en) * | 1990-07-03 | 1992-01-04 | CHARLES D. kELMAN | Collagen-based viscoelastic solution for visco-surgery |
| US5368585A (en) * | 1992-04-07 | 1994-11-29 | Dokken; Glenda K. | Reusable diaper and cover combination |
| TW274516B (https=) * | 1993-11-12 | 1996-04-21 | Ciba Geigy Ag | |
| IT1273011B (it) * | 1994-07-25 | 1997-07-01 | Trhecnopharma S A | Preparato oftalmico per l'uso come lacrima artificiale |
| AUPM784494A0 (en) * | 1994-09-02 | 1994-09-22 | Oversby Pty Ltd | A phacoemulsification needle |
| US5811453A (en) * | 1994-12-23 | 1998-09-22 | Alcon Laboratories, Inc. | Viscoelastic compositions and methods of use |
| US6231608B1 (en) * | 1995-06-07 | 2001-05-15 | Crosscart, Inc. | Aldehyde and glycosidase-treated soft and bone tissue xenografts |
| IT1277707B1 (it) * | 1995-12-22 | 1997-11-11 | Chemedica Sa | Formulazione oftalmica a base di ialuronato di sodio per uso nella chirurgia oculare |
| SE9700827D0 (sv) * | 1997-03-07 | 1997-03-07 | Pharmacia & Upjohn Ab | Ophthalmic composition |
| US6368585B1 (en) * | 1997-03-25 | 2002-04-09 | Pharmacia Ab | Opthalmic compositions and methods |
| ES2203238T3 (es) * | 1998-12-23 | 2004-04-01 | Esparma Gmbh | Agente para la proteccion de la piel que contiene acido hialuronico hidrolizado. |
| AU2001260178B2 (en) * | 2000-04-05 | 2005-12-15 | Schlumberger Technology B.V. | Viscosity reduction of viscoelastic surfactant based fluids |
| WO2002041877A1 (en) * | 2000-10-24 | 2002-05-30 | Clear Solutions Biotech, Inc. | Sodium hyaluronate microspheres |
| US6671903B2 (en) * | 2001-05-17 | 2004-01-06 | Douglas Bowers | Walking bag |
| US6558419B1 (en) * | 2001-11-08 | 2003-05-06 | Bausch & Lomb Incorporated | Intraocular lens |
| MXPA04008171A (es) * | 2002-02-22 | 2004-11-26 | Pharmacia Corp | Formulacion oftalmica con sistema de goma. |
-
2004
- 2004-03-29 US US10/812,551 patent/US20050215516A1/en not_active Abandoned
-
2005
- 2005-03-22 JP JP2007506237A patent/JP2007530226A/ja active Pending
- 2005-03-22 CN CNA2009100083060A patent/CN101485906A/zh active Pending
- 2005-03-22 KR KR1020067020196A patent/KR20060131938A/ko not_active Ceased
- 2005-03-22 CN CNB2005800102038A patent/CN100525847C/zh not_active Expired - Fee Related
- 2005-03-22 ES ES05726035T patent/ES2309735T3/es not_active Expired - Lifetime
- 2005-03-22 AU AU2005231687A patent/AU2005231687B2/en not_active Ceased
- 2005-03-22 AT AT05726035T patent/ATE401915T1/de not_active IP Right Cessation
- 2005-03-22 WO PCT/US2005/009512 patent/WO2005097226A1/en not_active Ceased
- 2005-03-22 EP EP05726035A patent/EP1732620B1/en not_active Expired - Lifetime
- 2005-03-22 DE DE602005008413T patent/DE602005008413D1/de not_active Expired - Lifetime
- 2005-03-22 CA CA2560943A patent/CA2560943C/en not_active Expired - Fee Related
-
2009
- 2009-10-19 US US12/581,242 patent/US20100036387A1/en not_active Abandoned
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