JP2007529223A5 - - Google Patents

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Publication number
JP2007529223A5
JP2007529223A5 JP2007504008A JP2007504008A JP2007529223A5 JP 2007529223 A5 JP2007529223 A5 JP 2007529223A5 JP 2007504008 A JP2007504008 A JP 2007504008A JP 2007504008 A JP2007504008 A JP 2007504008A JP 2007529223 A5 JP2007529223 A5 JP 2007529223A5
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JP
Japan
Prior art keywords
vector
polypeptide
cell
antibody
exon
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2007504008A
Other languages
English (en)
Japanese (ja)
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JP2007529223A (ja
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Publication date
Application filed filed Critical
Priority claimed from PCT/US2005/008473 external-priority patent/WO2005089285A2/en
Publication of JP2007529223A publication Critical patent/JP2007529223A/ja
Publication of JP2007529223A5 publication Critical patent/JP2007529223A5/ja
Pending legal-status Critical Current

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JP2007504008A 2004-03-15 2005-03-15 選択的スプライシングを用いて真核細胞においてポリペプチドマルチマーを発現するための方法および構築物 Pending JP2007529223A (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US55347804P 2004-03-15 2004-03-15
PCT/US2005/008473 WO2005089285A2 (en) 2004-03-15 2005-03-15 Methods and constructs for expressing polypeptide multimers in eukaryotic cells using alternative splicing

Publications (2)

Publication Number Publication Date
JP2007529223A JP2007529223A (ja) 2007-10-25
JP2007529223A5 true JP2007529223A5 (enExample) 2008-05-01

Family

ID=34994241

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2007504008A Pending JP2007529223A (ja) 2004-03-15 2005-03-15 選択的スプライシングを用いて真核細胞においてポリペプチドマルチマーを発現するための方法および構築物

Country Status (10)

Country Link
US (2) US7569362B2 (enExample)
EP (1) EP1733034A4 (enExample)
JP (1) JP2007529223A (enExample)
KR (1) KR20070004026A (enExample)
CN (1) CN1961071A (enExample)
AU (1) AU2005222963B2 (enExample)
BR (1) BRPI0508862A (enExample)
CA (1) CA2559280A1 (enExample)
IL (1) IL178051A (enExample)
WO (1) WO2005089285A2 (enExample)

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GB2402675B (en) * 2003-05-12 2008-02-20 Oxitec Ltd Resistance dilution
GB2403475B (en) * 2003-07-01 2008-02-06 Oxitec Ltd Stable integrands
GB2404382B (en) 2003-07-28 2008-01-30 Oxitec Ltd Pest control
CN1961071A (zh) * 2004-03-15 2007-05-09 比奥根艾迪克Ma公司 使用可选剪接在真核细胞中表达多肽多聚体的方法和构建物
GB2443186A (en) 2006-10-25 2008-04-30 Oxitec Ltd Expression system for mediating alternative splicing
AU2007213444B2 (en) * 2006-02-10 2013-08-29 Oxitec Limited Gene expression system using alternative splicing in insects
JP2009532027A (ja) 2006-03-28 2009-09-10 バイオジェン・アイデック・エムエイ・インコーポレイテッド 抗ｉｇｆ−１ｒ抗体およびその使用
US20090305343A1 (en) * 2006-05-16 2009-12-10 Millegen Method For Expressing Polypeptides In Eukaryotic Cells Using Alternative Splicing
BRPI0712073B8 (pt) 2006-05-17 2021-05-25 Hoffmann La Roche ácido nucléico para produção de um polipeptídio ou proteína heteróloga
US20080045419A1 (en) * 2006-08-18 2008-02-21 University Of North Texas Health Science Center At Fort Worth Screening Assay
CA2701338C (en) * 2007-10-15 2018-09-18 Chugai Seiyaku Kabushiki Kaisha Method for production of antibody
WO2009059235A2 (en) 2007-11-01 2009-05-07 Facet Biotech Corporation Immunoglobulin display vectors
KR100907221B1 (ko) * 2009-01-22 2009-07-10 한국과학기술원 새로운 조성의 황색 발광 Ｃｅ3+부활 칼슘 실리케이트 황색형광체를 포함하는 백색 발광 다이오드
EP2554681B1 (en) * 2010-03-31 2017-08-16 Tokyo University of Science Foundation Constitution of tool for analyzing biomolecular interaction and analysis method using same
AU2012332593B2 (en) 2011-11-01 2016-11-17 Bionomics, Inc. Anti-GPR49 antibodies
EP2773664A1 (en) 2011-11-01 2014-09-10 Bionomics, Inc. Anti-gpr49 antibodies
AU2012332588B2 (en) 2011-11-01 2017-09-07 Bionomics, Inc. Methods of blocking cancer stem cell growth
CN104053671A (zh) 2011-11-01 2014-09-17 生态学有限公司 治疗癌症的抗体和方法
BR112014012667A2 (pt) 2011-12-22 2018-10-09 F Hoffmann-La Roche Ag vetor de expressão, usos de vetor de expressão, método de transfecção de células eucarióticas, uso de método, uso de célula, métodos de produção de anticorpos e método de transfecção
GB2500113A (en) 2012-03-05 2013-09-11 Oxitec Ltd Arthropod male germline gene expression system
GB201303932D0 (en) 2013-03-05 2013-04-17 Oxitec Ltd Muscle actin promoter
EP2978849A2 (en) * 2013-03-30 2016-02-03 Usha Biotech Limited Methods and constructs for expressing biologically active proteins in mammalian cells
EP3030579A1 (en) * 2013-08-06 2016-06-15 Glenmark Pharmaceuticals S.A. Expression constructs and methods for expressing polypeptides in eukaryotic cells
US9546214B2 (en) 2014-04-04 2017-01-17 Bionomics, Inc. Humanized antibodies that bind LGR5
GB2526867A (en) 2014-06-05 2015-12-09 Oxitec Ltd Gene expression system
EP3432925A4 (en) 2016-03-22 2019-11-06 Bionomics Limited ADMINISTRATION OF A MONOCLONAL ANTI-LGR5 ANTIBODY
WO2018029534A1 (en) 2016-08-12 2018-02-15 Oxitec Ltd. A self-limiting, sex-specific gene and methods of using
EP3472198B1 (en) 2016-09-29 2020-03-04 H. Hoffnabb-La Roche Ag Improved method for selecting polypeptide producing cells
AR117409A1 (es) 2018-03-29 2021-08-04 Oxitec Ltd Noctuidas autolimitantes
SG11202100139VA (en) * 2018-07-17 2021-02-25 Neuromyon Inc Treatment of neuropathy with dna constructs expressing igf-1 isoforms
CA3152513A1 (en) * 2019-08-30 2021-03-04 Baylor College Of Medicine System for regulating gene expression
CN114150021B (zh) * 2021-11-26 2022-10-28 劲帆生物医药科技（武汉）有限公司 一种包含重叠开放阅读框的基因的表达盒及其在昆虫细胞中的应用

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JPS58192900A (ja) * 1982-05-04 1983-11-10 Ajinomoto Co Inc 複合プラスミド
US5043270A (en) * 1989-03-31 1991-08-27 The Board Of Trustees Of The Leland Stanford Junior University Intronic overexpression vectors
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US5587308A (en) * 1992-06-02 1996-12-24 The United States Of America As Represented By The Department Of Health & Human Services Modified adeno-associated virus vector capable of expression from a novel promoter
US5561053A (en) * 1994-08-05 1996-10-01 Genentech, Inc. Method for selecting high-expressing host cells
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US6900010B2 (en) * 1999-01-25 2005-05-31 Musc Foundation For Research Development Compositions and methods for detecting human immunodeficiency virus
EP1103614B1 (en) * 1999-06-04 2010-06-02 Nippon Institute for Biological Science Novel plasmid vector
WO2004046340A2 (en) * 2002-11-14 2004-06-03 Genentech, Inc. Intron fusion construct and method of using for selecting high-expressing production cell lines
WO2004074439A2 (en) * 2003-02-14 2004-09-02 Biogen Idec Ma Inc. An expression cassette and vector for transient or stable expression of exogenous molecules
CN1961071A (zh) * 2004-03-15 2007-05-09 比奥根艾迪克Ma公司 使用可选剪接在真核细胞中表达多肽多聚体的方法和构建物

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