JP2007527409A5 - - Google Patents
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- Publication number
- JP2007527409A5 JP2007527409A5 JP2006534354A JP2006534354A JP2007527409A5 JP 2007527409 A5 JP2007527409 A5 JP 2007527409A5 JP 2006534354 A JP2006534354 A JP 2006534354A JP 2006534354 A JP2006534354 A JP 2006534354A JP 2007527409 A5 JP2007527409 A5 JP 2007527409A5
- Authority
- JP
- Japan
- Prior art keywords
- pharmaceutical composition
- composition according
- group
- inverse agonist
- adrenergic
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 0 COc1c(CC(C(*)C2)O*)c2ccc1 Chemical compound COc1c(CC(C(*)C2)O*)c2ccc1 0.000 description 2
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US51025003P | 2003-10-09 | 2003-10-09 | |
| US55579704P | 2004-03-23 | 2004-03-23 | |
| PCT/US2004/033157 WO2005034871A2 (en) | 2003-10-09 | 2004-10-08 | Methods for treating diseases and conditions with inverse agonists |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2007527409A JP2007527409A (ja) | 2007-09-27 |
| JP2007527409A5 true JP2007527409A5 (https=) | 2008-01-17 |
Family
ID=34437322
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2006534354A Pending JP2007527409A (ja) | 2003-10-09 | 2004-10-08 | β−アドレナリンインバースアゴニストを用いて気道疾患を治療する方法 |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US9539221B2 (https=) |
| EP (2) | EP1684764A2 (https=) |
| JP (1) | JP2007527409A (https=) |
| AU (2) | AU2004279438A1 (https=) |
| CA (2) | CA2544733A1 (https=) |
| IL (1) | IL174765A0 (https=) |
| WO (2) | WO2005034871A2 (https=) |
Families Citing this family (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| MY140561A (en) | 2002-02-20 | 2009-12-31 | Nycomed Gmbh | Dosage form containing pde 4 inhibitor as active ingredient |
| PT1606261E (pt) | 2003-03-10 | 2010-01-11 | Nycomed Gmbh | Novo processo para a preparação de roflumilast |
| EP1725226A2 (en) * | 2004-03-17 | 2006-11-29 | Sosei R&D Ltd. | The treatment of inflammatory disorders and pain using beta-aminoalcohols |
| EP1755595A1 (en) * | 2004-05-10 | 2007-02-28 | Altana Pharma AG | Use of roflumilast for the prophylaxis or treatment of emphysema |
| US8691877B2 (en) | 2004-10-15 | 2014-04-08 | Palo Alto Investors | Methods and compositions for treating a disease condition in a subject |
| US8663694B2 (en) | 2005-03-16 | 2014-03-04 | Takeda Gmbh | Taste masked dosage form containing roflumilast |
| AU2006269944A1 (en) * | 2005-07-19 | 2007-01-25 | Inverseon, Inc. | Improved pharmacokinetic profile of beta-adrenergic inverse agonists for the treatment of pulmonary airway diseases |
| CA2807854A1 (en) * | 2009-08-12 | 2011-02-17 | Pulmosonix Pty Ltd | Determining dynamic airway response in a subject |
| WO2012096866A2 (en) * | 2011-01-10 | 2012-07-19 | Inverseon, Inc. | Use of beta-adrenergic inverse agonists for smoking cessation |
| US11382513B2 (en) | 2016-11-08 | 2022-07-12 | Palo Alto Investors | Methods and compositions for treating a condition in a subject |
| ES3040411T3 (en) | 2018-03-22 | 2025-10-30 | Incarda Therapeutics Inc | A novel method to slow ventricular rate |
| WO2020198466A1 (en) | 2019-03-27 | 2020-10-01 | Curasen Therapeutics, Inc. | Beta adrenergic agonist and methods of using the same |
| EP4076422A4 (en) | 2019-12-18 | 2024-01-24 | Curasen Therapeutics, Inc. | Methods for improving neurological diseases and disorders |
| WO2022192252A1 (en) * | 2021-03-09 | 2022-09-15 | Chronic Airway Therapeutics Limited | Use of nadolol to treat chronic obstructive pulmonary disease by blockage of the arrestin-2 pathway |
| WO2023250334A1 (en) * | 2022-06-21 | 2023-12-28 | Curasen Therapeutics, Inc. | Compositions and methods involving isolated compounds |
| WO2023250332A1 (en) * | 2022-06-21 | 2023-12-28 | Curasen Therapeutics, Inc. | Compositions and methods involving isolated compounds |
| CN116199596B (zh) * | 2023-03-06 | 2025-03-25 | 梯尔希(南京)药物研发有限公司 | 一种特布他林代谢物的制备方法 |
| WO2024189434A1 (en) * | 2023-03-13 | 2024-09-19 | Chronic Airway Therapeutics Limited | USE OF NADOLOL TO TREAT PULMONARY SYMPTOMS ASSOCIATED WITH INFECTIONS WITH SARS-CoV-2 |
Family Cites Families (39)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US36547A (en) * | 1862-09-23 | Improvement in locks | ||
| US4428926A (en) * | 1981-12-18 | 1984-01-31 | Key Pharmaceuticals, Inc. | Sustained release propranolol system |
| US5316759A (en) * | 1986-03-17 | 1994-05-31 | Robert J. Schaap | Agonist-antagonist combination to reduce the use of nicotine and other drugs |
| US4769372A (en) * | 1986-06-18 | 1988-09-06 | The Rockefeller University | Method of treating patients suffering from chronic pain or chronic cough |
| US5116867A (en) * | 1989-06-30 | 1992-05-26 | The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services | D-propranolol as a selective adenosine antagonist |
| US5352680A (en) * | 1992-07-15 | 1994-10-04 | Regents Of The University Of Minnesota | Delta opioid receptor antagonists to block opioid agonist tolerance and dependence |
| US5580876A (en) * | 1992-09-21 | 1996-12-03 | Albert Einstein College Of Medicine Of Yeshiva University, A Division Of Yeshiva University | Method of simultaneously enhancing analgesic potency and attenuating dependence liability caused by morphine and other bimodally-acting opioid agonists |
| USRE36547E (en) | 1992-09-21 | 2000-02-01 | Albert Einstein College Of Medicine Of Yeshiva University | Method of simultaneously enhancing analgesic potency and attenuating dependence liability caused by exogenous and endogenous opioid agonists |
| US5633259A (en) * | 1992-09-21 | 1997-05-27 | United Biomedical, Inc. | Method for identification of low/non-addictive opioid analgesics and the use of said analgesics for treatment of opioid addiction |
| US6096756A (en) * | 1992-09-21 | 2000-08-01 | Albert Einstein College Of Medicine Of Yeshiva University | Method of simultaneously enhancing analgesic potency and attenuating dependence liability caused by morphine and other bimodally-acting opioid agonists |
| US20010006967A1 (en) * | 1992-09-21 | 2001-07-05 | Stanley M. Crain | Method of simultaneously enhancing analgesic potency and attenuating adverse side effects caused by tramadol and other bimodally-acting opioid agonists |
| US5472943A (en) * | 1992-09-21 | 1995-12-05 | Albert Einstein College Of Medicine Of Yeshiva University, | Method of simultaneously enhancing analgesic potency and attenuating dependence liability caused by morphine and other opioid agonists |
| US6593094B2 (en) * | 1992-09-30 | 2003-07-15 | Richard G. Lanzara | Compositions to enhance the efficacy and safety of bio-pharmaceutical drugs |
| US6673558B1 (en) * | 1992-09-30 | 2004-01-06 | Richard G. Lanzara | Drug compositions to prevent desensitization of cellular receptors |
| US5597699A (en) * | 1992-09-30 | 1997-01-28 | Lanzara; Richard G. | Method for determining drug compositions to prevent desensitization of cellular receptors |
| US5585348A (en) * | 1993-02-10 | 1996-12-17 | Albert Einstein College Of Medicine Of Yeshiva University, A Division Of Yeshiva University | Use of excitatory opioid receptor antagonists to prevent growth factor-induced hyperalgesia |
| AU2068797A (en) * | 1996-01-29 | 1997-08-20 | Edward Mendell Co. Inc. | Sustained release excipient |
| JPH10251147A (ja) | 1997-03-06 | 1998-09-22 | Akira Matsumori | 炎症性疾患の予防・治療剤 |
| US6284800B1 (en) * | 1997-03-13 | 2001-09-04 | Baker Norton Pharmaceuticals, Inc. | Methods and compositions for treatment of asthma |
| US6555339B1 (en) * | 1997-04-14 | 2003-04-29 | Arena Pharmaceuticals, Inc. | Non-endogenous, constitutively activated human protein-coupled receptors |
| US6541209B1 (en) * | 1997-04-14 | 2003-04-01 | Arena Pharmaceuticals, Inc. | Non-endogenous, constitutively activated human serotonin receptors and small molecule modulators thereof |
| US6420541B1 (en) * | 1998-04-14 | 2002-07-16 | Arena Pharmaceuticals, Inc. | Non-endogenous, constitutively activated human serotonin receptors and small molecule modulators thereof |
| CA2316273A1 (en) * | 1998-01-16 | 1999-07-22 | Takeda Chemical Industries, Ltd. | Sustained-release composition, method of its production and use thereof |
| US6653086B1 (en) * | 1998-04-14 | 2003-11-25 | Arena Pharmaceuticals, Inc. | Endogenous constitutively activated G protein-coupled orphan receptors |
| MXPA00010060A (es) * | 1998-04-14 | 2004-04-23 | Arena Pharm Inc | Receptores de serotonina humana constitutivamente activados, no endogenos y moduladores de molecula pequenos de los mismos. |
| IL139254A0 (en) * | 1998-06-10 | 2001-11-25 | Arena Pharm Inc | Acetylcholine enhancers |
| US6140509A (en) * | 1998-06-26 | 2000-10-31 | Arena Pharmaceuticals, Inc. | Non-endogenous, constitutively activated human serotonin receptors and small molecule modulators thereof |
| US6420563B1 (en) * | 1998-07-31 | 2002-07-16 | Arena Pharmaceuticals, Inc. | Small molecule modulators of G protein-coupled receptor six |
| US6627632B2 (en) * | 1998-12-14 | 2003-09-30 | Cellegy Pharmaceuticals, Inc. | Compositions and methods for the treatment of anorectal disorders |
| US6150393A (en) * | 1998-12-18 | 2000-11-21 | Arena Pharmaceuticals, Inc. | Small molecule modulators of non-endogenous, constitutively activated human serotonin receptors |
| US6194382B1 (en) * | 1999-03-03 | 2001-02-27 | Albert Einstein College Of Medicine Of Yeshiva University | Method and composition for treating irritable bowel syndrome using low doses of opioid receptor antagonists |
| US6765010B2 (en) * | 1999-05-06 | 2004-07-20 | Pain Therapeutics, Inc. | Compositions and methods for enhancing analgesic potency of tramadol and attenuating its adverse side effects |
| CN1420929A (zh) * | 2000-04-07 | 2003-05-28 | 阿瑞那制药公司 | 非内源性组成型活化的已知g蛋白偶联受体 |
| AU2001292897A1 (en) | 2000-09-21 | 2002-04-02 | Richard Agustin Bond | Novel therapy |
| HUP0301377A3 (en) * | 2000-10-31 | 2005-12-28 | Boehringer Ingelheim Pharma | Combination pharmaceutical composition in form of inhalative solution containing a tiotropium salt |
| US7018812B2 (en) * | 2000-11-03 | 2006-03-28 | Duke University | Modified G-protein coupled receptors |
| AU2002305066B8 (en) * | 2001-03-23 | 2008-04-17 | Albert Einstein College Of Medicine Of Yeshiva University | Methods for increasing analgesic potency and attenuating adverse excitatory effects of bimodally-acting opioid agonists by inhibiting GM1-ganglioside |
| WO2003000735A2 (en) * | 2001-06-26 | 2003-01-03 | Decode Genetics Ehf. | Nucleic acids encoding olfactory receptors |
| US7149574B2 (en) * | 2003-06-09 | 2006-12-12 | Palo Alto Investors | Treatment of conditions through electrical modulation of the autonomic nervous system |
-
2004
- 2004-10-08 EP EP04794796A patent/EP1684764A2/en not_active Withdrawn
- 2004-10-08 US US10/574,677 patent/US9539221B2/en active Active
- 2004-10-08 AU AU2004279438A patent/AU2004279438A1/en not_active Abandoned
- 2004-10-08 WO PCT/US2004/033157 patent/WO2005034871A2/en not_active Ceased
- 2004-10-08 WO PCT/US2004/033530 patent/WO2005035731A2/en not_active Ceased
- 2004-10-08 EP EP04809893A patent/EP1677778A2/en not_active Withdrawn
- 2004-10-08 AU AU2004280638A patent/AU2004280638A1/en not_active Abandoned
- 2004-10-08 JP JP2006534354A patent/JP2007527409A/ja active Pending
- 2004-10-08 CA CA002544733A patent/CA2544733A1/en not_active Abandoned
- 2004-10-08 CA CA002544611A patent/CA2544611A1/en not_active Abandoned
-
2006
- 2006-04-03 IL IL174765A patent/IL174765A0/en unknown
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