JP2007526891A5 - - Google Patents
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- Publication number
- JP2007526891A5 JP2007526891A5 JP2006518502A JP2006518502A JP2007526891A5 JP 2007526891 A5 JP2007526891 A5 JP 2007526891A5 JP 2006518502 A JP2006518502 A JP 2006518502A JP 2006518502 A JP2006518502 A JP 2006518502A JP 2007526891 A5 JP2007526891 A5 JP 2007526891A5
- Authority
- JP
- Japan
- Prior art keywords
- antibody
- amino acid
- fzd10
- seq
- acid sequence
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 125000003275 alpha amino acid group Chemical group 0.000 claims 8
- 125000000539 amino acid group Chemical group 0.000 claims 8
- 239000012634 fragment Substances 0.000 claims 8
- 108090000765 processed proteins & peptides Proteins 0.000 claims 8
- 201000010099 disease Diseases 0.000 claims 6
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 claims 6
- 239000008194 pharmaceutical composition Substances 0.000 claims 5
- 208000031261 Acute myeloid leukaemia Diseases 0.000 claims 2
- 208000032791 BCR-ABL1 positive chronic myelogenous leukemia Diseases 0.000 claims 2
- 208000010833 Chronic myeloid leukaemia Diseases 0.000 claims 2
- 206010009944 Colon cancer Diseases 0.000 claims 2
- 208000001333 Colorectal Neoplasms Diseases 0.000 claims 2
- 208000033761 Myelogenous Chronic BCR-ABL Positive Leukemia Diseases 0.000 claims 2
- 208000033776 Myeloid Acute Leukemia Diseases 0.000 claims 2
- 208000005718 Stomach Neoplasms Diseases 0.000 claims 2
- 206010017758 gastric cancer Diseases 0.000 claims 2
- 238000004519 manufacturing process Methods 0.000 claims 2
- 108090000623 proteins and genes Proteins 0.000 claims 2
- 102000004169 proteins and genes Human genes 0.000 claims 2
- 201000011549 stomach cancer Diseases 0.000 claims 2
- 206010042863 synovial sarcoma Diseases 0.000 claims 2
- 239000003937 drug carrier Substances 0.000 claims 1
- 210000004408 hybridoma Anatomy 0.000 claims 1
- 239000000203 mixture Substances 0.000 claims 1
- 239000000546 pharmaceutical excipient Substances 0.000 claims 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US48619503P | 2003-07-11 | 2003-07-11 | |
| US60/486,195 | 2003-07-11 | ||
| PCT/JP2004/002144 WO2005004912A1 (en) | 2003-07-11 | 2004-02-24 | Method for treating synovial sarcoma |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2007526891A JP2007526891A (ja) | 2007-09-20 |
| JP2007526891A5 true JP2007526891A5 (enExample) | 2007-12-06 |
| JP4691626B2 JP4691626B2 (ja) | 2011-06-01 |
Family
ID=34062116
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2006518502A Expired - Lifetime JP4691626B2 (ja) | 2003-07-11 | 2004-02-24 | 滑膜肉腫の治療方法 |
Country Status (5)
| Country | Link |
|---|---|
| EP (1) | EP1648506B1 (enExample) |
| JP (1) | JP4691626B2 (enExample) |
| AT (1) | ATE545658T1 (enExample) |
| ES (1) | ES2381841T3 (enExample) |
| WO (1) | WO2005004912A1 (enExample) |
Families Citing this family (19)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7803370B2 (en) | 2002-08-30 | 2010-09-28 | Oncotherapy Science, Inc. | Method for treating synovial sarcoma |
| EP1561759B9 (en) | 2002-10-11 | 2009-08-26 | Chugai Seiyaku Kabushiki Kaisha | Cell death-inducing agent |
| JP5085322B2 (ja) | 2005-06-10 | 2012-11-28 | 中外製薬株式会社 | ｓｃ（Ｆｖ）２を含有する医薬組成物 |
| WO2006132363A1 (ja) | 2005-06-10 | 2006-12-14 | Chugai Seiyaku Kabushiki Kaisha | メグルミンを含有するタンパク質製剤の安定化剤、およびその利用 |
| DK2481756T3 (en) * | 2005-10-31 | 2017-10-09 | Oncomed Pharm Inc | Compositions and Methods for Diagnosing and Treating Cancer |
| US7723477B2 (en) | 2005-10-31 | 2010-05-25 | Oncomed Pharmaceuticals, Inc. | Compositions and methods for inhibiting Wnt-dependent solid tumor cell growth |
| EP2044123B1 (en) * | 2006-06-21 | 2013-03-13 | Oncotherapy Science, Inc. | Tumor-targeting monoclonal antibodies to fzd10 and uses thereof |
| BRPI0718850A2 (pt) * | 2006-11-14 | 2014-02-25 | Novartis Ag | Métodos de tratar, diagnosticar ou detectar câncer |
| CL2008000719A1 (es) * | 2007-03-12 | 2008-09-05 | Univ Tokushima Chugai Seiyaku | Agente terapeutico para cancer resistente a agentes quimioterapeuticos que comprende un anticuerpo que reconoce hla de clase i como ingrediente activo; composicion farmaceutica que comprende dicho anticuerpo; y metodo para tratar cancer resistente a |
| CN105079805A (zh) | 2008-09-26 | 2015-11-25 | 昂考梅德药品有限公司 | 卷曲蛋白结合药剂及其应用 |
| TWI535445B (zh) | 2010-01-12 | 2016-06-01 | 安可美德藥物股份有限公司 | Ｗｎｔ拮抗劑及治療和篩選方法 |
| NZ602700A (en) | 2010-04-01 | 2014-10-31 | Oncomed Pharm Inc | Frizzled-binding agents and uses thereof |
| JP6081995B2 (ja) | 2011-06-17 | 2017-02-15 | プレジデント・アンド・フェロウズ・オブ・ハーバード・カレッジ | 癌の処置における治療抗体の標的としてのＦｒｉｚｚｌｅｄ２ |
| JP5944994B2 (ja) * | 2011-08-12 | 2016-07-05 | オメロス コーポレーション | 抗ｆｚｄ１０モノクローナル抗体およびそれらの使用方法 |
| JP6155255B2 (ja) * | 2012-04-17 | 2017-06-28 | Hoya株式会社 | Ｆｚｄ１０結合性ペプチド |
| WO2014066328A1 (en) | 2012-10-23 | 2014-05-01 | Oncomed Pharmaceuticals, Inc. | Methods of treating neuroendocrine tumors using wnt pathway-binding agents |
| AU2014212081A1 (en) | 2013-02-04 | 2015-08-13 | Oncomed Pharmaceuticals, Inc. | Methods and monitoring of treatment with a Wnt pathway inhibitor |
| US9168300B2 (en) | 2013-03-14 | 2015-10-27 | Oncomed Pharmaceuticals, Inc. | MET-binding agents and uses thereof |
| TWI762516B (zh) * | 2016-10-06 | 2022-05-01 | 日商腫瘤療法 科學股份有限公司 | 針對ｆｚｄ１０之單株抗體及其用途 |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4946778A (en) | 1987-09-21 | 1990-08-07 | Genex Corporation | Single polypeptide chain binding molecules |
| GB9414580D0 (en) * | 1994-07-19 | 1994-09-07 | Cancer Res Campaign Tech | Materials and methods relating to the diagnosis of synovial sarcomas |
| US5994098A (en) * | 1997-06-02 | 1999-11-30 | Smithkline Beecham Corporation | Human 7-TM receptor similar to murine frizzled-6 gene |
| EP0943684A3 (en) * | 1998-03-10 | 2002-01-23 | Smithkline Beecham Plc | Frizzled-like polypeptides and polynucleotides |
| GB9819681D0 (en) * | 1998-09-09 | 1998-11-04 | Smithkline Beecham Plc | Novel compounds |
| JP2005508133A (ja) * | 2001-01-11 | 2005-03-31 | キュラジェン コーポレイション | タンパク質およびそれをコードする核酸 |
| US20030044409A1 (en) * | 2001-05-01 | 2003-03-06 | Carson Dennis A. | Immunologic compositions and methods for studying and treating cancers expressing frizzled antigens |
-
2004
- 2004-02-24 AT AT04713982T patent/ATE545658T1/de active
- 2004-02-24 EP EP04713982A patent/EP1648506B1/en not_active Expired - Lifetime
- 2004-02-24 JP JP2006518502A patent/JP4691626B2/ja not_active Expired - Lifetime
- 2004-02-24 WO PCT/JP2004/002144 patent/WO2005004912A1/en not_active Ceased
- 2004-02-24 ES ES04713982T patent/ES2381841T3/es not_active Expired - Lifetime
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