JP2007523093A - 非CpG核酸を使用した全身性免疫活性化法 - Google Patents

非CpG核酸を使用した全身性免疫活性化法 Download PDF

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JP2007523093A
JP2007523093A JP2006553373A JP2006553373A JP2007523093A JP 2007523093 A JP2007523093 A JP 2007523093A JP 2006553373 A JP2006553373 A JP 2006553373A JP 2006553373 A JP2006553373 A JP 2006553373A JP 2007523093 A JP2007523093 A JP 2007523093A
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nucleic acid
tumor
cells
cldc
composition
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JP2007523093A5 (https=
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ダブリュ. ダウ,スティーブン
フェアマン,ジェフェリー
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ジュバリス バイオセラピューティクス,インコーポレイティド
コロラド ステイト ユニバーシティ リサーチ ファウンデイション
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/10Dispersions; Emulsions
    • A61K9/127Synthetic bilayered vehicles, e.g. liposomes or liposomes with cholesterol as the only non-phosphatidyl surfactant
    • A61K9/1271Non-conventional liposomes, e.g. PEGylated liposomes or liposomes coated or grafted with polymers
    • A61K9/1272Non-conventional liposomes, e.g. PEGylated liposomes or liposomes coated or grafted with polymers comprising non-phosphatidyl surfactants as bilayer-forming substances, e.g. cationic lipids or non-phosphatidyl liposomes coated or grafted with polymers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • A61P37/04Immunostimulants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/08Antiallergic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Immunology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Dispersion Chemistry (AREA)
  • Epidemiology (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Virology (AREA)
  • Pulmonology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
JP2006553373A 2004-02-17 2005-02-17 非CpG核酸を使用した全身性免疫活性化法 Pending JP2007523093A (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US10/780,294 US20050181035A1 (en) 2004-02-17 2004-02-17 Systemic immune activation method using non CpG nucleic acids
PCT/US2005/005336 WO2005079511A2 (en) 2004-02-17 2005-02-17 SYSTEM IMMUNE ACTIVATION METHOD USING NON CpG NUCLEIC ACIDS

Publications (2)

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JP2007523093A true JP2007523093A (ja) 2007-08-16
JP2007523093A5 JP2007523093A5 (https=) 2008-04-03

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Family Applications (1)

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JP2006553373A Pending JP2007523093A (ja) 2004-02-17 2005-02-17 非CpG核酸を使用した全身性免疫活性化法

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US (1) US20050181035A1 (https=)
EP (1) EP1718149A4 (https=)
JP (1) JP2007523093A (https=)
AU (1) AU2005215020A1 (https=)
CA (1) CA2556229A1 (https=)
WO (1) WO2005079511A2 (https=)

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2011515490A (ja) * 2008-03-25 2011-05-19 ジュバリス・バイオセラピューティクス・インコーポレイテッド カチオン性脂質−dna複合体(cldc)の投与による免疫応答の増強
JP2012526734A (ja) * 2009-05-14 2012-11-01 バイエル・アニマル・ヘルス・ゲゼルシャフト・ミット・ベシュレンクテル・ハフツング 鳥類において増強された免疫応答
JP2020509039A (ja) * 2017-03-02 2020-03-26 ダンディ バイオサイエンス インコーポレイテッドDandi Bioscience Inc 免疫抑制因子制御物質を含む多重ドメインカプセル、その製造方法、及びこれを含む免疫調節組成物

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US6207646B1 (en) 1994-07-15 2001-03-27 University Of Iowa Research Foundation Immunostimulatory nucleic acid molecules
US20030026782A1 (en) 1995-02-07 2003-02-06 Arthur M. Krieg Immunomodulatory oligonucleotides
EP0855184A1 (en) * 1997-01-23 1998-07-29 Grayson B. Dr. Lipford Pharmaceutical composition comprising a polynucleotide and an antigen especially for vaccination
US20030022854A1 (en) 1998-06-25 2003-01-30 Dow Steven W. Vaccines using nucleic acid-lipid complexes
ES2572834T3 (es) 1999-02-17 2016-06-02 Csl Limited Complejos inmunogénicos y métodos relacionados con los mismos
NZ517929A (en) * 1999-09-25 2004-02-27 Univ Iowa Res Found Immunostimulatory nucleic acids
US11576958B2 (en) 2013-02-07 2023-02-14 Children's Medical Center Corporation Protein antigens that provide protection against pneumococcal colonization and/or disease
KR20160122849A (ko) 2014-02-28 2016-10-24 바이엘 애니멀 헬스 게엠베하 면역자극성 플라스미드
CN108064176A (zh) 2015-04-22 2018-05-22 库瑞瓦格股份公司 用于治疗肿瘤疾病的含有rna的组合物
SG10202000891UA (en) 2015-07-31 2020-03-30 Bayer Animal Health Gmbh Enhanced immune response in porcine species

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WO1999066879A2 (en) * 1998-06-25 1999-12-29 National Jewish Medical And Research Center Systemic immune activation method using nucleic acid-lipid complexes
WO2003101375A2 (en) * 2002-05-30 2003-12-11 Immunotech S.A. Immunostimulatory oligonucleotides and uses thereof

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US5703055A (en) * 1989-03-21 1997-12-30 Wisconsin Alumni Research Foundation Generation of antibodies through lipid mediated DNA delivery
US5693622A (en) * 1989-03-21 1997-12-02 Vical Incorporated Expression of exogenous polynucleotide sequences cardiac muscle of a mammal
US5399346A (en) * 1989-06-14 1995-03-21 The United States Of America As Represented By The Department Of Health And Human Services Gene therapy
US5013556A (en) * 1989-10-20 1991-05-07 Liposome Technology, Inc. Liposomes with enhanced circulation time
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US5705187A (en) * 1989-12-22 1998-01-06 Imarx Pharmaceutical Corp. Compositions of lipids and stabilizing materials
US5858784A (en) * 1991-12-17 1999-01-12 The Regents Of The University Of California Expression of cloned genes in the lung by aerosol- and liposome-based delivery
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Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1999066879A2 (en) * 1998-06-25 1999-12-29 National Jewish Medical And Research Center Systemic immune activation method using nucleic acid-lipid complexes
WO2003101375A2 (en) * 2002-05-30 2003-12-11 Immunotech S.A. Immunostimulatory oligonucleotides and uses thereof

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2011515490A (ja) * 2008-03-25 2011-05-19 ジュバリス・バイオセラピューティクス・インコーポレイテッド カチオン性脂質−dna複合体(cldc)の投与による免疫応答の増強
JP2012526734A (ja) * 2009-05-14 2012-11-01 バイエル・アニマル・ヘルス・ゲゼルシャフト・ミット・ベシュレンクテル・ハフツング 鳥類において増強された免疫応答
JP2020509039A (ja) * 2017-03-02 2020-03-26 ダンディ バイオサイエンス インコーポレイテッドDandi Bioscience Inc 免疫抑制因子制御物質を含む多重ドメインカプセル、その製造方法、及びこれを含む免疫調節組成物
JP2020510663A (ja) * 2017-03-02 2020-04-09 ダンディ バイオサイエンス インコーポレイテッドDandi Bioscience Inc 免疫活性物質を含む多重ドメインカプセル、その製造方法、及びこれを含む免疫調節組成物

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US20050181035A1 (en) 2005-08-18
AU2005215020A1 (en) 2005-09-01
EP1718149A2 (en) 2006-11-08
WO2005079511A3 (en) 2006-01-19
CA2556229A1 (en) 2005-09-01
EP1718149A4 (en) 2010-06-09
WO2005079511A2 (en) 2005-09-01

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