JP2007522094A5 - - Google Patents
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- Publication number
- JP2007522094A5 JP2007522094A5 JP2006527154A JP2006527154A JP2007522094A5 JP 2007522094 A5 JP2007522094 A5 JP 2007522094A5 JP 2006527154 A JP2006527154 A JP 2006527154A JP 2006527154 A JP2006527154 A JP 2006527154A JP 2007522094 A5 JP2007522094 A5 JP 2007522094A5
- Authority
- JP
- Japan
- Prior art keywords
- kinase
- drug
- hexokinase
- complex
- optionally
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
Links
- 102000001253 Protein Kinase Human genes 0.000 claims 2
- 239000003814 drug Substances 0.000 claims 2
- 229940079593 drug Drugs 0.000 claims 2
- 108060006633 protein kinase Proteins 0.000 claims 2
- 102000005548 Hexokinase Human genes 0.000 claims 1
- 108700040460 Hexokinases Proteins 0.000 claims 1
- 108091000080 Phosphotransferase Proteins 0.000 claims 1
- 150000002632 lipids Chemical class 0.000 claims 1
- 102000020233 phosphotransferase Human genes 0.000 claims 1
- 239000000758 substrate Substances 0.000 claims 1
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US50532503P | 2003-09-22 | 2003-09-22 | |
US58183504P | 2004-06-22 | 2004-06-22 | |
PCT/US2004/031147 WO2005030258A2 (en) | 2003-09-22 | 2004-09-22 | Small molecule compositions and methods for increasing drug efficiency using compositions thereof |
Publications (2)
Publication Number | Publication Date |
---|---|
JP2007522094A JP2007522094A (ja) | 2007-08-09 |
JP2007522094A5 true JP2007522094A5 (es) | 2007-12-06 |
Family
ID=34396244
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP2006527154A Abandoned JP2007522094A (ja) | 2003-09-22 | 2004-09-22 | 小分子組成物、及びその組成物を使用して薬物効率を高めるための方法 |
Country Status (5)
Country | Link |
---|---|
EP (1) | EP1689439A2 (es) |
JP (1) | JP2007522094A (es) |
AU (1) | AU2004275770A1 (es) |
CA (1) | CA2539914A1 (es) |
WO (1) | WO2005030258A2 (es) |
Families Citing this family (33)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
MY164523A (en) | 2000-05-23 | 2017-12-29 | Univ Degli Studi Cagliari | Methods and compositions for treating hepatitis c virus |
KR20030036189A (ko) | 2000-05-26 | 2003-05-09 | 이데닉스(케이만)리미티드 | 플라비바이러스 및 페스티바이러스의 치료방법 및 조성물 |
KR20050088079A (ko) | 2002-11-15 | 2005-09-01 | 이데닉스 (케이만) 리미티드 | 2'-분지형 뉴클레오시드 및 플라비비리다에 돌연변이 |
US8138361B2 (en) | 2005-12-28 | 2012-03-20 | The Trustees Of The University Of Pennsylvania | C-10 carbamates of taxanes |
US7960139B2 (en) | 2007-03-23 | 2011-06-14 | Academia Sinica | Alkynyl sugar analogs for the labeling and visualization of glycoconjugates in cells |
CN102105135B (zh) * | 2008-05-23 | 2016-08-24 | 英属哥伦比亚大学 | 用于脂质体纳米颗粒的修饰的药物 |
EP2318832B1 (en) | 2008-07-15 | 2013-10-09 | Academia Sinica | Glycan arrays on ptfe-like aluminum coated glass slides and related methods |
US10087236B2 (en) | 2009-12-02 | 2018-10-02 | Academia Sinica | Methods for modifying human antibodies by glycan engineering |
US11377485B2 (en) | 2009-12-02 | 2022-07-05 | Academia Sinica | Methods for modifying human antibodies by glycan engineering |
US10338069B2 (en) | 2010-04-12 | 2019-07-02 | Academia Sinica | Glycan arrays for high throughput screening of viruses |
US10130714B2 (en) | 2012-04-14 | 2018-11-20 | Academia Sinica | Enhanced anti-influenza agents conjugated with anti-inflammatory activity |
US9914956B2 (en) | 2012-08-18 | 2018-03-13 | Academia Sinica | Cell-permeable probes for identification and imaging of sialidases |
US9556216B2 (en) | 2012-08-31 | 2017-01-31 | Novartis Ag | 2′-Ethynyl nucleoside derivatives for treatment of viral infections |
CA2891125A1 (en) | 2012-11-19 | 2014-05-22 | Merck Sharp & Dohme Corp. | 2 -alkynyl substituted nucleoside derivatives for treating viral diseases |
EP3013365B1 (en) | 2013-06-26 | 2019-06-05 | Academia Sinica | Rm2 antigens and use thereof |
WO2014210564A1 (en) | 2013-06-27 | 2014-12-31 | Academia Sinica | Glycan conjugates and use thereof |
US9782476B2 (en) | 2013-09-06 | 2017-10-10 | Academia Sinica | Human iNKT cell activation using glycolipids with altered glycosyl groups |
JP2017507118A (ja) | 2014-01-16 | 2017-03-16 | アカデミア シニカAcademia Sinica | がんの処置および検出のための組成物および方法 |
US10150818B2 (en) | 2014-01-16 | 2018-12-11 | Academia Sinica | Compositions and methods for treatment and detection of cancers |
TWI687428B (zh) | 2014-03-27 | 2020-03-11 | 中央研究院 | 反應性標記化合物及其用途 |
EP3149045B1 (en) | 2014-05-27 | 2023-01-18 | Academia Sinica | Compositions and methods relating to universal glycoforms for enhanced antibody efficacy |
US10118969B2 (en) | 2014-05-27 | 2018-11-06 | Academia Sinica | Compositions and methods relating to universal glycoforms for enhanced antibody efficacy |
KR102512592B1 (ko) | 2014-05-27 | 2023-03-21 | 아카데미아 시니카 | 항-her2 글리코항체 및 이의 용도 |
CA2950415A1 (en) | 2014-05-27 | 2015-12-03 | Academia Sinica | Anti-cd20 glycoantibodies and uses thereof |
KR102494193B1 (ko) | 2014-05-28 | 2023-01-31 | 아카데미아 시니카 | 항-tnf-알파 글리코항체 및 이의 용도 |
KR102422375B1 (ko) | 2014-09-08 | 2022-07-18 | 아카데미아 시니카 | 당지질을 사용한 인간 iNKT 세포 활성화 |
US9975965B2 (en) | 2015-01-16 | 2018-05-22 | Academia Sinica | Compositions and methods for treatment and detection of cancers |
US10495645B2 (en) | 2015-01-16 | 2019-12-03 | Academia Sinica | Cancer markers and methods of use thereof |
EP3248005B1 (en) | 2015-01-24 | 2020-12-09 | Academia Sinica | Novel glycan conjugates and methods of use thereof |
JP2019515876A (ja) | 2016-03-08 | 2019-06-13 | アカデミア シニカAcademia Sinica | N−グリカンおよびそのアレイのモジュール合成のための方法 |
CN109963868B (zh) | 2016-08-22 | 2023-11-14 | 醣基生医股份有限公司 | 抗体、结合片段及使用方法 |
KR20210021984A (ko) * | 2018-05-15 | 2021-03-02 | 인터크 펩타이드 테라퓨틱스 리미티드 | 펩타이드 활성화 제제 |
AU2019268411B2 (en) * | 2018-05-15 | 2024-03-14 | Interk Peptide Therapeutics Limited | Activating agents |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
IL59083A (en) * | 1979-01-10 | 1983-12-30 | Israel Marcus | Pharmaceutical composition containing thymidine and a salicyclic acid derivative as a solubilizing agent therefor |
US5608049A (en) * | 1995-03-10 | 1997-03-04 | Bristol-Myers Squibb Company | Preparation of d4T from 5-methyluridine |
US5723589A (en) * | 1995-12-21 | 1998-03-03 | Icn Pharmaceuticals | Carbohydrate conjugated bio-active compounds |
-
2004
- 2004-09-22 AU AU2004275770A patent/AU2004275770A1/en not_active Abandoned
- 2004-09-22 EP EP04784836A patent/EP1689439A2/en not_active Withdrawn
- 2004-09-22 CA CA002539914A patent/CA2539914A1/en not_active Abandoned
- 2004-09-22 WO PCT/US2004/031147 patent/WO2005030258A2/en not_active Application Discontinuation
- 2004-09-22 JP JP2006527154A patent/JP2007522094A/ja not_active Abandoned
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