PT1718340E - Novos conjugados de efectores, processo para a sua produção e sua utilização farmacêutica - Google Patents
Novos conjugados de efectores, processo para a sua produção e sua utilização farmacêutica Download PDFInfo
- Publication number
- PT1718340E PT1718340E PT05707090T PT05707090T PT1718340E PT 1718340 E PT1718340 E PT 1718340E PT 05707090 T PT05707090 T PT 05707090T PT 05707090 T PT05707090 T PT 05707090T PT 1718340 E PT1718340 E PT 1718340E
- Authority
- PT
- Portugal
- Prior art keywords
- production
- pharmaceutical use
- new effector
- effector conjugates
- conjugates
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
- A61K47/68—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an antibody, an immunoglobulin or a fragment thereof, e.g. an Fc-fragment
- A61K47/6835—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an antibody, an immunoglobulin or a fragment thereof, e.g. an Fc-fragment the modifying agent being an antibody or an immunoglobulin bearing at least one antigen-binding site
- A61K47/6849—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an antibody, an immunoglobulin or a fragment thereof, e.g. an Fc-fragment the modifying agent being an antibody or an immunoglobulin bearing at least one antigen-binding site the antibody targeting a receptor, a cell surface antigen or a cell surface determinant
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/02—Antineoplastic agents specific for leukemia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- General Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Neurosurgery (AREA)
- Hematology (AREA)
- Cardiology (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Heart & Thoracic Surgery (AREA)
- Hospice & Palliative Care (AREA)
- Oncology (AREA)
- Ophthalmology & Optometry (AREA)
- Psychiatry (AREA)
- Cell Biology (AREA)
- Immunology (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
- Plural Heterocyclic Compounds (AREA)
- Medicinal Preparation (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US53997704P | 2004-01-30 | 2004-01-30 | |
| DE102004004787A DE102004004787A1 (de) | 2004-01-30 | 2004-01-30 | Neue Effektor-Konjugate, Verfahren zu ihrer Herstellung und ihre pharmazeutische Verwendung |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PT1718340E true PT1718340E (pt) | 2008-02-07 |
Family
ID=34839581
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PT05707090T PT1718340E (pt) | 2004-01-30 | 2005-01-31 | Novos conjugados de efectores, processo para a sua produção e sua utilização farmacêutica |
Country Status (10)
| Country | Link |
|---|---|
| EP (1) | EP1718340B1 (pt) |
| JP (1) | JP2007519681A (pt) |
| CY (1) | CY1107207T1 (pt) |
| DE (1) | DE602005003453T2 (pt) |
| DK (1) | DK1718340T3 (pt) |
| ES (1) | ES2296133T3 (pt) |
| PL (1) | PL1718340T3 (pt) |
| PT (1) | PT1718340E (pt) |
| SI (1) | SI1718340T1 (pt) |
| WO (1) | WO2005074901A2 (pt) |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2006012527A1 (en) | 2004-07-23 | 2006-02-02 | Endocyte, Inc. | Bivalent linkers and conjugates thereof |
| PE20080316A1 (es) | 2006-05-25 | 2008-04-10 | Bristol Myers Squibb Co | Compuestos de aziridinil-epotilona |
| NZ599239A (en) | 2007-03-14 | 2013-10-25 | Endocyte Inc | Binding ligand linked drug delivery conjugates of tubulysins |
| US8143415B2 (en) | 2007-05-25 | 2012-03-27 | Bristol-Myers Squibb Company | Processes for making epothilone compounds and analogs |
| EP2160408A1 (en) * | 2007-06-22 | 2010-03-10 | Bayer Schering Pharma Aktiengesellschaft | Use of antibodies against the cd52 antigen for the treatment of neurological disorders, particularly transmissible spongiform encephalopathy and alzheimer's disease |
| US9877965B2 (en) | 2007-06-25 | 2018-01-30 | Endocyte, Inc. | Vitamin receptor drug delivery conjugates for treating inflammation |
| AU2008268432B2 (en) | 2007-06-25 | 2015-01-15 | Endocyte, Inc. | Conjugates containing hydrophilic spacer linkers |
| JP2011500835A (ja) | 2007-10-25 | 2011-01-06 | エンドサイト，インコーポレイテッド | チューブリシン類および調製プロセス |
| US10080805B2 (en) | 2012-02-24 | 2018-09-25 | Purdue Research Foundation | Cholecystokinin B receptor targeting for imaging and therapy |
| US20140080175A1 (en) | 2012-03-29 | 2014-03-20 | Endocyte, Inc. | Processes for preparing tubulysin derivatives and conjugates thereof |
| CA2887727A1 (en) | 2012-10-16 | 2014-04-24 | Endocyte, Inc. | Drug delivery conjugates containing unnatural amino acids and methods for using |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE10305098A1 (de) * | 2003-02-07 | 2004-08-19 | Schering Ag | Neue Effektor-Konjugate, Verfahren zu ihrer Herstellung und ihre pharmazeutische Verwendung |
| DE10234975A1 (de) * | 2002-07-31 | 2004-02-12 | Schering Ag | Neue Effektor-Konjugate, Verfahren zu ihrer Herstellung und ihre pharmazeutische Verwendung |
| WO2004012735A2 (en) * | 2002-07-31 | 2004-02-12 | Schering Ag | New effector conjugates, process for their production and their pharmaceutical use |
| US20040126379A1 (en) * | 2002-08-21 | 2004-07-01 | Boehringer Ingelheim International Gmbh | Compositions and methods for treating cancer using cytotoxic CD44 antibody immunoconjugates and chemotherapeutic agents |
| WO2004050089A1 (en) * | 2002-12-05 | 2004-06-17 | Schering Ag | Epothilone analogs for site specific delivery in the treatment of proliferative diseases |
| DE10256982A1 (de) * | 2002-12-05 | 2004-06-24 | Schering Ag | Neue Effektor-Konjugate, Verfahren zu Ihrer Herstellung und Ihre Pharmazeutische Verwendung |
-
2005
- 2005-01-31 JP JP2006550125A patent/JP2007519681A/ja not_active Withdrawn
- 2005-01-31 SI SI200530139T patent/SI1718340T1/sl unknown
- 2005-01-31 DE DE602005003453T patent/DE602005003453T2/de not_active Expired - Fee Related
- 2005-01-31 DK DK05707090T patent/DK1718340T3/da active
- 2005-01-31 WO PCT/EP2005/000917 patent/WO2005074901A2/en active IP Right Grant
- 2005-01-31 ES ES05707090T patent/ES2296133T3/es active Active
- 2005-01-31 EP EP05707090A patent/EP1718340B1/en not_active Not-in-force
- 2005-01-31 PT PT05707090T patent/PT1718340E/pt unknown
- 2005-01-31 PL PL05707090T patent/PL1718340T3/pl unknown
-
2008
- 2008-02-21 CY CY20081100203T patent/CY1107207T1/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| WO2005074901A3 (en) | 2006-03-30 |
| EP1718340B1 (en) | 2007-11-21 |
| PL1718340T3 (pl) | 2008-04-30 |
| EP1718340A2 (en) | 2006-11-08 |
| DE602005003453T2 (de) | 2008-09-25 |
| DE602005003453D1 (de) | 2008-01-03 |
| JP2007519681A (ja) | 2007-07-19 |
| SI1718340T1 (sl) | 2008-04-30 |
| CY1107207T1 (el) | 2012-11-21 |
| ES2296133T3 (es) | 2008-04-16 |
| WO2005074901A2 (en) | 2005-08-18 |
| DK1718340T3 (da) | 2008-03-03 |
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