JP2007520565A5 - - Google Patents
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- Publication number
- JP2007520565A5 JP2007520565A5 JP2006552282A JP2006552282A JP2007520565A5 JP 2007520565 A5 JP2007520565 A5 JP 2007520565A5 JP 2006552282 A JP2006552282 A JP 2006552282A JP 2006552282 A JP2006552282 A JP 2006552282A JP 2007520565 A5 JP2007520565 A5 JP 2007520565A5
- Authority
- JP
- Japan
- Prior art keywords
- animal
- human
- pharmaceutical composition
- pharmaceutical
- composition
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 239000008194 pharmaceutical composition Substances 0.000 claims 1
- 0 CC(*(C)I)C=C(C(N(**)C1=C)=C)N(C)C1=I Chemical compound CC(*(C)I)C=C(C(N(**)C1=C)=C)N(C)C1=I 0.000 description 2
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US54207304P | 2004-02-04 | 2004-02-04 | |
| US62426204P | 2004-11-01 | 2004-11-01 | |
| PCT/US2005/003636 WO2005077940A1 (en) | 2004-02-04 | 2005-02-04 | Dehydrophenylahistins and analogs thereof and the synthesis of dehydrophenylahistins and analogs thereof |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2007520565A JP2007520565A (ja) | 2007-07-26 |
| JP2007520565A5 true JP2007520565A5 (enrdf_load_stackoverflow) | 2008-04-03 |
Family
ID=34864489
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2006552282A Pending JP2007520565A (ja) | 2004-02-04 | 2005-02-04 | デヒドロフェニラヒスチン及びそれらの類似体、並びにデヒドロフェニラヒスチン及びそれらの類似体の合成 |
Country Status (9)
Families Citing this family (21)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2004054498A2 (en) | 2002-08-02 | 2004-07-01 | Nereus Pharmaceuticals, Inc. | Dehydrophenylahistins and analogs thereof and the synthesis of dehydrophenylahistins and analogs thereof |
| US7935704B2 (en) | 2003-08-01 | 2011-05-03 | Nereus Pharmaceuticals, Inc. | Dehydrophenylahistins and analogs thereof and the synthesis of dehydrophenylahistins and analogs thereof |
| US7919497B2 (en) | 2002-08-02 | 2011-04-05 | Nereus Pharmaceuticals, Inc. | Analogs of dehydrophenylahistins and their therapeutic use |
| WO2007035841A1 (en) * | 2005-09-21 | 2007-03-29 | Nereus Pharmaceuticals, Inc. | Analogs of dehydrophenylahistins and their therapeutic use |
| US8129527B2 (en) | 2006-11-03 | 2012-03-06 | Nereus Pharmacuticals, Inc. | Analogs of dehydrophenylahistins and their therapeutic use |
| WO2015051543A1 (en) | 2013-10-11 | 2015-04-16 | Dalian Wanchun Biotechnology Co., Ltd. | Cancer treatment with combination of plinabulin and taxane |
| CA2975729A1 (en) * | 2015-02-12 | 2016-08-18 | Beyondspring Pharmaceuticals, Inc. | Use of plinabulin in combination with immune checkpoint inhibitors |
| JP6904570B2 (ja) * | 2015-03-06 | 2021-07-21 | ビヨンドスプリング ファーマシューティカルズ,インコーポレイテッド | 脳腫瘍の治療方法 |
| RU2736045C2 (ru) | 2015-03-06 | 2020-11-11 | Бейондспринг Фармасьютикалс, Инк. | Способ лечения рака, ассоциированного с мутацией ras |
| CA2991059C (en) | 2015-07-13 | 2024-01-16 | Beyondspring Pharmaceuticals, Inc. | Plinabulin monohydrate polymorphs |
| WO2017139231A1 (en) | 2016-02-08 | 2017-08-17 | Beyondspring Pharmaceuticals, Inc. | Compositions containing tucaresol or its analogs |
| KR20190015361A (ko) | 2016-06-06 | 2019-02-13 | 비욘드스프링 파마수티컬스, 인코포레이티드. | 호중구감소증을 줄이는 조성물 및 방법 |
| US10851086B2 (en) | 2016-08-12 | 2020-12-01 | Marine Biomedical Research Institute Of Qingdao Co., Ltd. | Polycrystalline form of dehydrophenylahistin-like compound, and manufacturing and purification method and application thereof |
| WO2018129381A1 (en) | 2017-01-06 | 2018-07-12 | Beyondspring Pharmaceuticals, Inc. | Tubulin binding compounds and therapeutic use thereof |
| AU2018217120B2 (en) | 2017-02-01 | 2024-02-08 | Beyondspring Pharmaceuticals, Inc. | Method of reducing neutropenia |
| EP3595653B1 (en) * | 2017-03-13 | 2023-03-08 | Beyondspring Pharmaceuticals, Inc. | Compositions of plinabulin and use thereof |
| CN112135614A (zh) | 2018-01-24 | 2020-12-25 | 大连万春布林医药有限公司 | 通过施用普那布林减少血小板减少症的组合物和方法 |
| CN108524442B (zh) * | 2018-06-05 | 2022-01-28 | 深圳海王医药科技研究院有限公司 | 一种抗肿瘤药物的注射剂及其制备方法 |
| JP2018199726A (ja) * | 2018-09-26 | 2018-12-20 | ビヨンドスプリング インコーポレイテッド | プリナブリン及びタキサンの組合せがん治療 |
| JP2024513505A (ja) | 2021-04-09 | 2024-03-25 | ビヨンドスプリング ファーマシューティカルズ,インコーポレイテッド | 腫瘍を治療するための組成物及び方法 |
| CN118369101A (zh) * | 2021-10-07 | 2024-07-19 | 大连万春布林医药有限公司 | 治疗癌症和肿瘤的方法 |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE3318789C2 (de) * | 1983-05-24 | 1987-04-02 | Eduard Gerlach GmbH Chemische Fabrik, 4990 Lübbecke | Deodorant |
| GB9402807D0 (en) * | 1994-02-14 | 1994-04-06 | Xenova Ltd | Pharmaceutical compounds |
| US6069146A (en) * | 1998-03-25 | 2000-05-30 | The Regents Of The University Of California | Halimide, a cytotoxic marine natural product, and derivatives thereof |
| US6358957B1 (en) * | 1998-11-12 | 2002-03-19 | Nereus Pharmaceuticals, Inc. | Phenylahistin and the phenylahistin analogs, a new class of anti-tumor compounds |
| NZ519989A (en) * | 2000-01-18 | 2004-05-28 | Nereus Pharmaceuticals Inc | Cell division inhibitors and process for producing the same |
| WO2001095858A2 (en) * | 2000-05-09 | 2001-12-20 | Adpharma, Inc. | Piperazinedione compounds |
| WO2004054498A2 (en) * | 2002-08-02 | 2004-07-01 | Nereus Pharmaceuticals, Inc. | Dehydrophenylahistins and analogs thereof and the synthesis of dehydrophenylahistins and analogs thereof |
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2005
- 2005-02-04 EP EP05712910A patent/EP1711487A1/en not_active Withdrawn
- 2005-02-04 CA CA002553630A patent/CA2553630A1/en not_active Abandoned
- 2005-02-04 JP JP2006552282A patent/JP2007520565A/ja active Pending
- 2005-02-04 NZ NZ548659A patent/NZ548659A/en not_active IP Right Cessation
- 2005-02-04 KR KR1020067017883A patent/KR101228104B1/ko not_active Expired - Lifetime
- 2005-02-04 BR BRPI0506655-7A patent/BRPI0506655A/pt not_active IP Right Cessation
- 2005-02-04 WO PCT/US2005/003636 patent/WO2005077940A1/en not_active Ceased
- 2005-02-04 AU AU2005212399A patent/AU2005212399B2/en not_active Ceased
-
2006
- 2006-07-18 IL IL176932A patent/IL176932A0/en unknown