JP2007520565A5 - - Google Patents
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- JP2007520565A5 JP2007520565A5 JP2006552282A JP2006552282A JP2007520565A5 JP 2007520565 A5 JP2007520565 A5 JP 2007520565A5 JP 2006552282 A JP2006552282 A JP 2006552282A JP 2006552282 A JP2006552282 A JP 2006552282A JP 2007520565 A5 JP2007520565 A5 JP 2007520565A5
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- JP
- Japan
- Prior art keywords
- animal
- human
- pharmaceutical composition
- pharmaceutical
- composition
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 239000008194 pharmaceutical composition Substances 0.000 claims 1
- 0 CC(*(C)I)C=C(C(N(**)C1=C)=C)N(C)C1=I Chemical compound CC(*(C)I)C=C(C(N(**)C1=C)=C)N(C)C1=I 0.000 description 2
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US54207304P | 2004-02-04 | 2004-02-04 | |
US62426204P | 2004-11-01 | 2004-11-01 | |
PCT/US2005/003636 WO2005077940A1 (en) | 2004-02-04 | 2005-02-04 | Dehydrophenylahistins and analogs thereof and the synthesis of dehydrophenylahistins and analogs thereof |
Publications (2)
Publication Number | Publication Date |
---|---|
JP2007520565A JP2007520565A (ja) | 2007-07-26 |
JP2007520565A5 true JP2007520565A5 (enrdf_load_stackoverflow) | 2008-04-03 |
Family
ID=34864489
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP2006552282A Pending JP2007520565A (ja) | 2004-02-04 | 2005-02-04 | デヒドロフェニラヒスチン及びそれらの類似体、並びにデヒドロフェニラヒスチン及びそれらの類似体の合成 |
Country Status (9)
Families Citing this family (21)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US7935704B2 (en) | 2003-08-01 | 2011-05-03 | Nereus Pharmaceuticals, Inc. | Dehydrophenylahistins and analogs thereof and the synthesis of dehydrophenylahistins and analogs thereof |
US7919497B2 (en) | 2002-08-02 | 2011-04-05 | Nereus Pharmaceuticals, Inc. | Analogs of dehydrophenylahistins and their therapeutic use |
JP4616649B2 (ja) | 2002-08-02 | 2011-01-19 | ネレアス ファーマシューティカルズ インコーポレイテッド | デヒドロフェニラヒスチンおよびそれらの類似体、ならびにデヒドロフェニラヒスチンおよびそれらの類似体の合成 |
WO2007035841A1 (en) * | 2005-09-21 | 2007-03-29 | Nereus Pharmaceuticals, Inc. | Analogs of dehydrophenylahistins and their therapeutic use |
US8129527B2 (en) | 2006-11-03 | 2012-03-06 | Nereus Pharmacuticals, Inc. | Analogs of dehydrophenylahistins and their therapeutic use |
RU2662298C2 (ru) * | 2013-10-11 | 2018-07-25 | Бьёндспринг Инк. | Лечение рака комбинацией плинабулина и таксана |
SG11201706281YA (en) * | 2015-02-12 | 2017-09-28 | Beyondspring Pharmaceuticals Inc | Use of plinabulin in combination with immune checkpoint inhibitors |
SG10202008673WA (en) | 2015-03-06 | 2020-10-29 | Beyondspring Pharmaceuticals Inc | Method of treating cancer associated with a ras mutation |
US10076518B2 (en) * | 2015-03-06 | 2018-09-18 | Beyondspring Pharmaceuticals, Inc. | Method of treating a brain tumor |
EP3334726B1 (en) * | 2015-07-13 | 2022-03-16 | Beyondspring Pharmaceuticals, Inc. | Plinabulin compositions |
NZ744854A (en) | 2016-02-08 | 2020-01-31 | Beyondspring Pharmaceuticals Inc | Compositions containing tucaresol or its analogs |
AU2017278245B2 (en) | 2016-06-06 | 2022-09-15 | Beyondspring Pharmaceuticals, Inc. | Composition and method for reducing neutropenia |
CN109563079B (zh) * | 2016-08-12 | 2021-10-26 | 深圳华大海洋科技有限公司 | 脱氢苯基阿夕斯丁类化合物的多晶型及其制备纯化方法和应用 |
JP2020503363A (ja) | 2017-01-06 | 2020-01-30 | ビヨンドスプリング ファーマシューティカルズ,インコーポレイテッド | チューブリン結合化合物およびその治療的使用 |
KR20190109479A (ko) | 2017-02-01 | 2019-09-25 | 비욘드스프링 파마수티컬스, 인코포레이티드. | 호중구감소증의 감소 방법 |
AU2018236168B2 (en) * | 2017-03-13 | 2024-02-29 | Beyondspring Pharmaceuticals, Inc. | Compositions of plinabulin and use thereof |
JP7350015B2 (ja) | 2018-01-24 | 2023-09-25 | ビヨンドスプリング ファーマシューティカルズ,インコーポレイテッド | プリナブリンの投与による血小板減少症を軽減するための組成物および方法 |
CN108524442B (zh) * | 2018-06-05 | 2022-01-28 | 深圳海王医药科技研究院有限公司 | 一种抗肿瘤药物的注射剂及其制备方法 |
JP2018199726A (ja) * | 2018-09-26 | 2018-12-20 | ビヨンドスプリング インコーポレイテッド | プリナブリン及びタキサンの組合せがん治療 |
JP2024513505A (ja) | 2021-04-09 | 2024-03-25 | ビヨンドスプリング ファーマシューティカルズ,インコーポレイテッド | 腫瘍を治療するための組成物及び方法 |
WO2023060200A1 (en) * | 2021-10-07 | 2023-04-13 | Beyondspring Pharmaceuticals, Inc. | Methods for treating cancers and tumors |
Family Cites Families (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE3318789C2 (de) * | 1983-05-24 | 1987-04-02 | Eduard Gerlach GmbH Chemische Fabrik, 4990 Lübbecke | Deodorant |
GB9402807D0 (en) * | 1994-02-14 | 1994-04-06 | Xenova Ltd | Pharmaceutical compounds |
US6069146A (en) * | 1998-03-25 | 2000-05-30 | The Regents Of The University Of California | Halimide, a cytotoxic marine natural product, and derivatives thereof |
US6358957B1 (en) * | 1998-11-12 | 2002-03-19 | Nereus Pharmaceuticals, Inc. | Phenylahistin and the phenylahistin analogs, a new class of anti-tumor compounds |
BRPI0017067B8 (pt) * | 2000-01-18 | 2021-05-25 | Beyondspring Pharmaceuticals Inc | inibidor de divisão de célula, desidrogenase, método para a produção de um inibidor de divisão de célula e composto |
DE60137037D1 (de) * | 2000-05-09 | 2009-01-29 | Angiorx Corp | Piperazindion-verbindungen |
JP4616649B2 (ja) * | 2002-08-02 | 2011-01-19 | ネレアス ファーマシューティカルズ インコーポレイテッド | デヒドロフェニラヒスチンおよびそれらの類似体、ならびにデヒドロフェニラヒスチンおよびそれらの類似体の合成 |
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2005
- 2005-02-04 BR BRPI0506655-7A patent/BRPI0506655A/pt not_active IP Right Cessation
- 2005-02-04 CA CA002553630A patent/CA2553630A1/en not_active Abandoned
- 2005-02-04 KR KR1020067017883A patent/KR101228104B1/ko not_active Expired - Lifetime
- 2005-02-04 NZ NZ548659A patent/NZ548659A/en not_active IP Right Cessation
- 2005-02-04 JP JP2006552282A patent/JP2007520565A/ja active Pending
- 2005-02-04 AU AU2005212399A patent/AU2005212399B2/en not_active Ceased
- 2005-02-04 EP EP05712910A patent/EP1711487A1/en not_active Withdrawn
- 2005-02-04 WO PCT/US2005/003636 patent/WO2005077940A1/en active Application Filing
-
2006
- 2006-07-18 IL IL176932A patent/IL176932A0/en unknown