|
US7872133B2
(en)
|
2003-06-23 |
2011-01-18 |
Ono Pharmaceutical Co., Ltd. |
Tricyclic heterocycle compound
|
|
UA92317C2
(ru)
|
2004-03-15 |
2010-10-25 |
Пи-Ти-Си ТЕРАПЬЮТИКС, ИНК. |
Производные карболина, пригодные для ингибирования развития кровеносных сосудов
|
|
US7767689B2
(en)
*
|
2004-03-15 |
2010-08-03 |
Ptc Therapeutics, Inc. |
Carboline derivatives useful in the treatment of cancer
|
|
US8076353B2
(en)
|
2004-03-15 |
2011-12-13 |
Ptc Therapeutics, Inc. |
Inhibition of VEGF translation
|
|
US8076352B2
(en)
|
2004-03-15 |
2011-12-13 |
Ptc Therapeutics, Inc. |
Administration of carboline derivatives useful in the treatment of cancer and other diseases
|
|
EP1829874B1
(en)
|
2004-12-22 |
2014-02-12 |
Ono Pharmaceutical Co., Ltd. |
Tricyclic compound and use thereof
|
|
US8119655B2
(en)
|
2005-10-07 |
2012-02-21 |
Takeda Pharmaceutical Company Limited |
Kinase inhibitors
|
|
SG158147A1
(en)
|
2006-10-09 |
2010-01-29 |
Takeda Pharmaceutical |
Kinase inhibitors
|
|
WO2008103470A2
(en)
|
2007-02-21 |
2008-08-28 |
Trustees Of Columbia University In The City Of New York |
Oncogenic-ras-signal dependent lethal compounds
|
|
US11202775B2
(en)
|
2007-09-25 |
2021-12-21 |
Minerva Biotechnologies Corporation |
Methods for treatment of cancer
|
|
EP2214485B1
(en)
*
|
2007-09-25 |
2016-07-20 |
Minerva Biotechnologies Corp. |
Methods for treatment of cancer
|
|
EP2050747A1
(en)
*
|
2007-10-12 |
2009-04-22 |
BioAlliance Pharma |
Dimers of harmol or of its derivatives and uses thereof
|
|
KR101614723B1
(ko)
|
2008-01-11 |
2016-04-22 |
알바니 몰레큘라 리써치, 인크. |
Ｍｃｈ 길항물질로서 (1-아지논)-치환된 피리도인돌
|
|
CN101591348B
(zh)
*
|
2008-05-30 |
2011-07-27 |
首都医科大学 |
四氢咔啉酰氨基酸苄酯及其制备方法和应用
|
|
CN101597289B
(zh)
*
|
2008-06-02 |
2011-09-21 |
首都医科大学 |
2-色氨酰-β-四氢咔啉-3-甲酰基氨基酸苄酯及其制备方法和应用
|
|
WO2010138685A1
(en)
|
2009-05-27 |
2010-12-02 |
Ptc Therapeutics, Inc. |
Methods for treating prostate conditions
|
|
MX373926B
(es)
|
2009-05-27 |
2020-07-10 |
Ptc Therapeutics Inc |
Metodos para tratar cancer y estados no neoplasicos.
|
|
CA2763479A1
(en)
|
2009-05-27 |
2010-12-02 |
Ptc Therapeutics, Inc. |
Processes for the preparation of substituted tetrahydro beta-carbolines
|
|
WO2010138652A1
(en)
|
2009-05-27 |
2010-12-02 |
Ptc Therapeutics, Inc. |
Methods for treating kaposi sarcoma
|
|
JP2012532144A
(ja)
|
2009-07-01 |
2012-12-13 |
アルバニー モレキュラー リサーチ， インコーポレイテッド |
アジノン置換アゼピノ［ｂ］インドールおよびピリド−ピロロ−アゼピンｍｃｈ−１拮抗薬、ならびにその作製方法および使用
|
|
US8618299B2
(en)
*
|
2009-07-01 |
2013-12-31 |
Albany Molecular Research, Inc. |
Azinone-substituted azapolycycle MCH-1 antagonists, methods of making, and use thereof
|
|
WO2011003007A1
(en)
*
|
2009-07-01 |
2011-01-06 |
Albany Molecular Research, Inc. |
Azabicycloalkane-indole and azabicycloalkane-pyrrolo-pyridine mch-1 antagonists, methods of making, and use thereof
|
|
US9073925B2
(en)
*
|
2009-07-01 |
2015-07-07 |
Albany Molecular Research, Inc. |
Azinone-substituted azabicycloalkane-indole and azabicycloalkane-pyrrolo-pyridine MCH-1 antagonists, methods of making, and use thereof
|
|
FR2953839A1
(fr)
*
|
2009-12-14 |
2011-06-17 |
Sanofi Aventis |
Nouveaux derives d'(heterocycle-piperidine condensee)-(piperazinyl)-1alcanone ou d'(heterocycle-pyrrolidine condensee)-(piperazinyl)-1alcanone et leur utilisation comme inhibiteurs de p75
|
|
ES2693247T3
(es)
*
|
2010-07-06 |
2018-12-10 |
Ono Pharmaceutical Co., Ltd. |
Derivado de tetrahidrocarbolina
|
|
US8993765B2
(en)
|
2010-12-21 |
2015-03-31 |
Albany Molecular Research, Inc. |
Tetrahydro-azacarboline MCH-1 antagonists, methods of making, and uses thereof
|
|
US8697700B2
(en)
|
2010-12-21 |
2014-04-15 |
Albany Molecular Research, Inc. |
Piperazinone-substituted tetrahydro-carboline MCH-1 antagonists, methods of making, and uses thereof
|
|
WO2012127885A1
(ja)
|
2011-03-18 |
2012-09-27 |
小野薬品工業株式会社 |
テトラヒドロカルボリン誘導体
|
|
EP3366685A1
(en)
*
|
2012-01-09 |
2018-08-29 |
X-Chem, Inc. |
Tryptoline derivatives having kinase inhibitory activity and uses thereof
|
|
CN103087062B
(zh)
*
|
2013-01-19 |
2015-06-03 |
安徽师范大学 |
N-磺酰基取代-β-四氢咔啉衍生物的制备方法
|
|
UY35590A
(es)
*
|
2013-05-28 |
2014-11-28 |
Astrazeneca Ab |
Nuevos compuestos para el tratamiento del cáncer
|
|
US11931347B2
(en)
|
2015-09-23 |
2024-03-19 |
Minerva Biotechnologies Corporation |
Method of screening for agents for differentiating stem cells
|
|
JP2019001715A
(ja)
*
|
2015-10-30 |
2019-01-10 |
協和発酵キリン株式会社 |
三環性化合物
|
|
JP6592197B2
(ja)
*
|
2015-11-12 |
2019-10-16 |
浙江海正薬業股▲ふん▼有限公司Ｚｈｅｊｉａｎｇ Ｈｉｓｕｎ Ｐｈａｒｍａｃｅｕｔｉｃａｌ ＣＯ．，ＬＴＤ． |
アクリル酸誘導体、製造方法、および医薬としてのその使用
|
|
CN106967063B
(zh)
*
|
2017-03-21 |
2019-01-11 |
浙江大学 |
1-三氟甲基-1,2,3,4-四氢-β-咔啉衍生物及其制备方法
|
|
EP3664803A4
(en)
|
2017-08-01 |
2021-05-05 |
PTC Therapeutics, Inc. |
DHODH INHIBITOR FOR USE IN THE TREATMENT OF HEMATOLOGICAL CANCERS
|
|
WO2020072675A1
(en)
|
2018-10-02 |
2020-04-09 |
Northwestern University |
Beta-carbolines as positive allosteric modulators of the human serotonin receptor 2c (5-ht2c)
|
|
CN110791389B
(zh)
*
|
2019-09-30 |
2021-06-01 |
义乌欧风汽车用品有限公司 |
一种除胶剂及其制备方法和应用
|
|
US20250186437A1
(en)
*
|
2021-12-31 |
2025-06-12 |
Ptc Therapeutics, Inc. |
Carboline compounds and use thereof
|
|
CN120265629A
(zh)
*
|
2022-11-07 |
2025-07-04 |
默克专利股份公司 |
被取代的双环和三环hset抑制剂
|