JP2007518801A5 - - Google Patents
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- Publication number
- JP2007518801A5 JP2007518801A5 JP2006551170A JP2006551170A JP2007518801A5 JP 2007518801 A5 JP2007518801 A5 JP 2007518801A5 JP 2006551170 A JP2006551170 A JP 2006551170A JP 2006551170 A JP2006551170 A JP 2006551170A JP 2007518801 A5 JP2007518801 A5 JP 2007518801A5
- Authority
- JP
- Japan
- Prior art keywords
- composition according
- atiii
- composition
- lung injury
- administered
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 239000000203 mixture Substances 0.000 claims 28
- 102000004411 Antithrombin III Human genes 0.000 claims 24
- 108090000935 Antithrombin III Proteins 0.000 claims 24
- 229960005348 antithrombin iii Drugs 0.000 claims 24
- 208000004852 Lung Injury Diseases 0.000 claims 10
- 206010069363 Traumatic lung injury Diseases 0.000 claims 10
- 231100000515 lung injury Toxicity 0.000 claims 10
- 206010069351 acute lung injury Diseases 0.000 claims 3
- 230000037396 body weight Effects 0.000 claims 3
- 239000000126 substance Substances 0.000 claims 3
- 208000019693 Lung disease Diseases 0.000 claims 2
- 230000001580 bacterial effect Effects 0.000 claims 2
- 239000003937 drug carrier Substances 0.000 claims 2
- 210000004072 lung Anatomy 0.000 claims 2
- 206010001052 Acute respiratory distress syndrome Diseases 0.000 claims 1
- 208000005623 Carcinogenesis Diseases 0.000 claims 1
- 208000029523 Interstitial Lung disease Diseases 0.000 claims 1
- 206010035610 Pleural Neoplasms Diseases 0.000 claims 1
- 241000589517 Pseudomonas aeruginosa Species 0.000 claims 1
- 208000021063 Respiratory fume inhalation disease Diseases 0.000 claims 1
- FAPWRFPIFSIZLT-UHFFFAOYSA-M Sodium chloride Chemical compound [Na+].[Cl-] FAPWRFPIFSIZLT-UHFFFAOYSA-M 0.000 claims 1
- 239000000443 aerosol Substances 0.000 claims 1
- 125000003158 alcohol group Chemical group 0.000 claims 1
- KXNPVXPOPUZYGB-XYVMCAHJSA-N argatroban Chemical compound OC(=O)[C@H]1C[C@H](C)CCN1C(=O)[C@H](CCCN=C(N)N)NS(=O)(=O)C1=CC=CC2=C1NC[C@H](C)C2 KXNPVXPOPUZYGB-XYVMCAHJSA-N 0.000 claims 1
- 229960003856 argatroban Drugs 0.000 claims 1
- 239000010425 asbestos Substances 0.000 claims 1
- 230000036952 cancer formation Effects 0.000 claims 1
- 231100000504 carcinogenesis Toxicity 0.000 claims 1
- 229940112141 dry powder inhaler Drugs 0.000 claims 1
- 231100000516 lung damage Toxicity 0.000 claims 1
- 239000008267 milk Substances 0.000 claims 1
- 210000004080 milk Anatomy 0.000 claims 1
- 235000013336 milk Nutrition 0.000 claims 1
- 239000006199 nebulizer Substances 0.000 claims 1
- 201000003437 pleural cancer Diseases 0.000 claims 1
- 208000008423 pleurisy Diseases 0.000 claims 1
- 108090000623 proteins and genes Proteins 0.000 claims 1
- 230000002685 pulmonary effect Effects 0.000 claims 1
- 229910052895 riebeckite Inorganic materials 0.000 claims 1
- 239000011780 sodium chloride Substances 0.000 claims 1
- 230000005740 tumor formation Effects 0.000 claims 1
- 230000008728 vascular permeability Effects 0.000 claims 1
- 230000003612 virological effect Effects 0.000 claims 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims 1
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US53867804P | 2004-01-23 | 2004-01-23 | |
| US60/538,678 | 2004-01-23 | ||
| US11/034,590 US20050169908A1 (en) | 2004-01-23 | 2005-01-13 | Use of aerosolized antithrombin to treat acute lung injury |
| US11/034,590 | 2005-01-13 | ||
| PCT/US2005/001238 WO2005072139A2 (en) | 2004-01-23 | 2005-01-14 | Use of aerosolized antithrombin to treat acute lung injury |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2007518801A JP2007518801A (ja) | 2007-07-12 |
| JP2007518801A5 true JP2007518801A5 (https=) | 2008-10-16 |
| JP4854519B2 JP4854519B2 (ja) | 2012-01-18 |
Family
ID=34810485
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2006551170A Expired - Fee Related JP4854519B2 (ja) | 2004-01-23 | 2005-01-14 | 急性肺損傷の治療におけるエアロゾル化アンチトロンビンの使用法 |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US20050169908A1 (https=) |
| EP (1) | EP1713500A2 (https=) |
| JP (1) | JP4854519B2 (https=) |
| KR (1) | KR20060127992A (https=) |
| AU (1) | AU2005208552A1 (https=) |
| CA (1) | CA2553758A1 (https=) |
| IL (1) | IL177028A0 (https=) |
| WO (1) | WO2005072139A2 (https=) |
Families Citing this family (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2480790A1 (en) * | 2002-04-01 | 2003-10-16 | Kazunori Murakami | Use of antithrombin iii in treating acute lung injury |
| US20050192226A1 (en) * | 2004-02-20 | 2005-09-01 | Perenlei Enkhbaatar | Method of preventing fibrin clots in pulmonary tissue through the use of aerosolized anticoagulants |
| US20050245444A1 (en) * | 2004-04-30 | 2005-11-03 | Yann Echelard | Method of using recombinant human antithrombin for neurocognitive disorders |
| US20060121004A1 (en) * | 2004-12-07 | 2006-06-08 | Yann Echelard | Methods of reducing the incidence of rejection in tissue transplantation through the use of recombinant human antithrombin |
| ES2811526T3 (es) | 2010-12-30 | 2021-03-12 | Lab Francais Du Fractionnement | Glicoles como agentes de inactivación de patógenos |
| WO2014089327A1 (en) * | 2012-12-05 | 2014-06-12 | National Jewish Health | Treatment for airway cast obstruction |
| US10034921B2 (en) | 2013-02-13 | 2018-07-31 | Laboratoire Français Du Fractionnement Et Des Biotechnologies | Proteins with modified glycosylation and methods of production thereof |
| EP3594230A1 (en) | 2013-02-13 | 2020-01-15 | Laboratoire Français du Fractionnement et des Biotechnologies | Highly galactosylated anti-tnf-alpha antibodies and uses thereof |
| EP3016729B1 (fr) | 2013-07-05 | 2020-03-25 | Laboratoire Francais du Fractionnement et des Biotechnologies Societe Anonyme | Matrice de chromatographie d'affinité |
| PE20160789A1 (es) | 2013-11-04 | 2016-08-17 | Univ Texas | Composiciones y metodos para admistracion de una enzima a las vias respiratorias de un sujeto |
| WO2016118625A1 (en) * | 2015-01-20 | 2016-07-28 | Incarda Therapeutics, Inc. | Unit aerosol doses for anticoagulation |
| WO2016179447A1 (en) * | 2015-05-06 | 2016-11-10 | Board Of Regents, The University Of Texas System | Compositions and methods for administration of an enzyme to a subject's airway |
| FR3038517B1 (fr) | 2015-07-06 | 2020-02-28 | Laboratoire Francais Du Fractionnement Et Des Biotechnologies | Utilisation de fragments fc modifies en immunotherapie |
| US11654036B2 (en) | 2020-05-26 | 2023-05-23 | Elixir Medical Corporation | Anticoagulant compounds and methods and devices for their use |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6127347A (en) * | 1994-01-12 | 2000-10-03 | Univ Michigan | Non-anticoagulant chemically modified heparinoids for treating hypovolemic shock and related shock syndromes |
| US5843705A (en) * | 1995-02-21 | 1998-12-01 | Genzyme Transgenic Corporation | Transgenically produced antithrombin III |
| US7045585B2 (en) * | 1995-11-30 | 2006-05-16 | Hamilton Civic Hospital Research Development Inc. | Methods of coating a device using anti-thrombin heparin |
| US6063593A (en) * | 1996-11-12 | 2000-05-16 | University Of Southern California University Park Campus | TGFβ1 responsive bone marrow derived cells to express a recombinant protein |
| US6124257A (en) * | 1997-08-28 | 2000-09-26 | Lezdey; John | Method of treatment |
| DE10132307A1 (de) * | 2001-07-06 | 2003-01-30 | Aventis Behring Gmbh | Arzneizubereitung zur Inhalation von Antithrombin bei entzündlichen Lungenerkrankungen und ARDS |
| CA2480790A1 (en) * | 2002-04-01 | 2003-10-16 | Kazunori Murakami | Use of antithrombin iii in treating acute lung injury |
| US20050192226A1 (en) * | 2004-02-20 | 2005-09-01 | Perenlei Enkhbaatar | Method of preventing fibrin clots in pulmonary tissue through the use of aerosolized anticoagulants |
-
2005
- 2005-01-13 US US11/034,590 patent/US20050169908A1/en not_active Abandoned
- 2005-01-14 JP JP2006551170A patent/JP4854519B2/ja not_active Expired - Fee Related
- 2005-01-14 AU AU2005208552A patent/AU2005208552A1/en not_active Abandoned
- 2005-01-14 CA CA002553758A patent/CA2553758A1/en not_active Abandoned
- 2005-01-14 KR KR1020067016937A patent/KR20060127992A/ko not_active Abandoned
- 2005-01-14 WO PCT/US2005/001238 patent/WO2005072139A2/en not_active Ceased
- 2005-01-14 EP EP05705713A patent/EP1713500A2/en not_active Withdrawn
-
2006
- 2006-07-23 IL IL177028A patent/IL177028A0/en unknown
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