JP2007533657A5 - - Google Patents
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- Publication number
- JP2007533657A5 JP2007533657A5 JP2006554156A JP2006554156A JP2007533657A5 JP 2007533657 A5 JP2007533657 A5 JP 2007533657A5 JP 2006554156 A JP2006554156 A JP 2006554156A JP 2006554156 A JP2006554156 A JP 2006554156A JP 2007533657 A5 JP2007533657 A5 JP 2007533657A5
- Authority
- JP
- Japan
- Prior art keywords
- composition
- antithrombin iii
- administered
- heparin
- lung
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 239000000203 mixture Substances 0.000 claims 25
- 102000004411 Antithrombin III Human genes 0.000 claims 17
- 108090000935 Antithrombin III Proteins 0.000 claims 17
- 229960005348 antithrombin iii Drugs 0.000 claims 17
- HTTJABKRGRZYRN-UHFFFAOYSA-N Heparin Chemical compound OC1C(NC(=O)C)C(O)OC(COS(O)(=O)=O)C1OC1C(OS(O)(=O)=O)C(O)C(OC2C(C(OS(O)(=O)=O)C(OC3C(C(O)C(O)C(O3)C(O)=O)OS(O)(=O)=O)C(CO)O2)NS(O)(=O)=O)C(C(O)=O)O1 HTTJABKRGRZYRN-UHFFFAOYSA-N 0.000 claims 8
- 229960002897 heparin Drugs 0.000 claims 8
- 229920000669 heparin Polymers 0.000 claims 8
- 208000019693 Lung disease Diseases 0.000 claims 5
- 230000037396 body weight Effects 0.000 claims 4
- 208000004852 Lung Injury Diseases 0.000 claims 2
- 206010069363 Traumatic lung injury Diseases 0.000 claims 2
- 230000001580 bacterial effect Effects 0.000 claims 2
- 239000003937 drug carrier Substances 0.000 claims 2
- 231100000515 lung injury Toxicity 0.000 claims 2
- 239000006199 nebulizer Substances 0.000 claims 2
- 239000000126 substance Substances 0.000 claims 2
- 230000005740 tumor formation Effects 0.000 claims 2
- 206010001052 Acute respiratory distress syndrome Diseases 0.000 claims 1
- 208000029523 Interstitial Lung disease Diseases 0.000 claims 1
- 206010035610 Pleural Neoplasms Diseases 0.000 claims 1
- 206010035664 Pneumonia Diseases 0.000 claims 1
- 241000589516 Pseudomonas Species 0.000 claims 1
- 208000021063 Respiratory fume inhalation disease Diseases 0.000 claims 1
- FAPWRFPIFSIZLT-UHFFFAOYSA-M Sodium chloride Chemical compound [Na+].[Cl-] FAPWRFPIFSIZLT-UHFFFAOYSA-M 0.000 claims 1
- 230000001154 acute effect Effects 0.000 claims 1
- 206010069351 acute lung injury Diseases 0.000 claims 1
- 239000010425 asbestos Substances 0.000 claims 1
- 210000004072 lung Anatomy 0.000 claims 1
- 208000020816 lung neoplasm Diseases 0.000 claims 1
- 208000037841 lung tumor Diseases 0.000 claims 1
- 201000003437 pleural cancer Diseases 0.000 claims 1
- 208000008423 pleurisy Diseases 0.000 claims 1
- 239000000843 powder Substances 0.000 claims 1
- 108090000623 proteins and genes Proteins 0.000 claims 1
- 230000002685 pulmonary effect Effects 0.000 claims 1
- 229910052895 riebeckite Inorganic materials 0.000 claims 1
- 239000000779 smoke Substances 0.000 claims 1
- 239000011780 sodium chloride Substances 0.000 claims 1
- 230000008728 vascular permeability Effects 0.000 claims 1
- 230000003612 virological effect Effects 0.000 claims 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US54623604P | 2004-02-20 | 2004-02-20 | |
| US11/057,522 US20050192226A1 (en) | 2004-02-20 | 2005-02-14 | Method of preventing fibrin clots in pulmonary tissue through the use of aerosolized anticoagulants |
| PCT/US2005/004604 WO2005081816A2 (en) | 2004-02-20 | 2005-02-15 | Method of preventing fibrin clots in pulmonary tissue through the use of aerosolized anticoagulants |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2011109632A Division JP2011162555A (ja) | 2004-02-20 | 2011-05-16 | エアロゾル化抗凝固薬を用いて肺組織におけるフィブリンクロットの形成を防ぐ方法 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2007533657A JP2007533657A (ja) | 2007-11-22 |
| JP2007533657A5 true JP2007533657A5 (https=) | 2010-06-17 |
Family
ID=34889863
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2006554156A Pending JP2007533657A (ja) | 2004-02-20 | 2005-02-15 | エアロゾル化抗凝固薬を用いて肺組織におけるフィブリンクロットの形成を防ぐ方法 |
| JP2011109632A Pending JP2011162555A (ja) | 2004-02-20 | 2011-05-16 | エアロゾル化抗凝固薬を用いて肺組織におけるフィブリンクロットの形成を防ぐ方法 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2011109632A Pending JP2011162555A (ja) | 2004-02-20 | 2011-05-16 | エアロゾル化抗凝固薬を用いて肺組織におけるフィブリンクロットの形成を防ぐ方法 |
Country Status (10)
| Country | Link |
|---|---|
| US (2) | US20050192226A1 (https=) |
| EP (2) | EP1725244B1 (https=) |
| JP (2) | JP2007533657A (https=) |
| KR (3) | KR20060130661A (https=) |
| AT (1) | ATE493135T1 (https=) |
| AU (1) | AU2005216044B2 (https=) |
| CA (1) | CA2557411A1 (https=) |
| DE (1) | DE602005025610D1 (https=) |
| IL (1) | IL177588A0 (https=) |
| WO (1) | WO2005081816A2 (https=) |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2480790A1 (en) * | 2002-04-01 | 2003-10-16 | Kazunori Murakami | Use of antithrombin iii in treating acute lung injury |
| US20050169908A1 (en) * | 2004-01-23 | 2005-08-04 | Kazunori Murakami | Use of aerosolized antithrombin to treat acute lung injury |
| US20050192226A1 (en) * | 2004-02-20 | 2005-09-01 | Perenlei Enkhbaatar | Method of preventing fibrin clots in pulmonary tissue through the use of aerosolized anticoagulants |
| US20050245444A1 (en) * | 2004-04-30 | 2005-11-03 | Yann Echelard | Method of using recombinant human antithrombin for neurocognitive disorders |
| US20060121004A1 (en) * | 2004-12-07 | 2006-06-08 | Yann Echelard | Methods of reducing the incidence of rejection in tissue transplantation through the use of recombinant human antithrombin |
| ES2811526T3 (es) | 2010-12-30 | 2021-03-12 | Lab Francais Du Fractionnement | Glicoles como agentes de inactivación de patógenos |
| WO2014089327A1 (en) * | 2012-12-05 | 2014-06-12 | National Jewish Health | Treatment for airway cast obstruction |
| EP3594230A1 (en) | 2013-02-13 | 2020-01-15 | Laboratoire Français du Fractionnement et des Biotechnologies | Highly galactosylated anti-tnf-alpha antibodies and uses thereof |
| US10034921B2 (en) | 2013-02-13 | 2018-07-31 | Laboratoire Français Du Fractionnement Et Des Biotechnologies | Proteins with modified glycosylation and methods of production thereof |
| EP3016729B1 (fr) | 2013-07-05 | 2020-03-25 | Laboratoire Francais du Fractionnement et des Biotechnologies Societe Anonyme | Matrice de chromatographie d'affinité |
| FR3038517B1 (fr) | 2015-07-06 | 2020-02-28 | Laboratoire Francais Du Fractionnement Et Des Biotechnologies | Utilisation de fragments fc modifies en immunotherapie |
Family Cites Families (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6127347A (en) * | 1994-01-12 | 2000-10-03 | Univ Michigan | Non-anticoagulant chemically modified heparinoids for treating hypovolemic shock and related shock syndromes |
| US6355626B1 (en) * | 1994-05-13 | 2002-03-12 | The Trustees Of The University Of Pennsylvania | Antithrombin agents in treatment of asthma |
| US5843705A (en) * | 1995-02-21 | 1998-12-01 | Genzyme Transgenic Corporation | Transgenically produced antithrombin III |
| US7045585B2 (en) * | 1995-11-30 | 2006-05-16 | Hamilton Civic Hospital Research Development Inc. | Methods of coating a device using anti-thrombin heparin |
| US6063593A (en) * | 1996-11-12 | 2000-05-16 | University Of Southern California University Park Campus | TGFβ1 responsive bone marrow derived cells to express a recombinant protein |
| US6124257A (en) * | 1997-08-28 | 2000-09-26 | Lezdey; John | Method of treatment |
| AU2440802A (en) * | 2000-10-18 | 2002-04-29 | Massachusetts Inst Technology | Methods and products related to pulmonary delivery of polysaccharides |
| DE10132307A1 (de) | 2001-07-06 | 2003-01-30 | Aventis Behring Gmbh | Arzneizubereitung zur Inhalation von Antithrombin bei entzündlichen Lungenerkrankungen und ARDS |
| CA2480790A1 (en) * | 2002-04-01 | 2003-10-16 | Kazunori Murakami | Use of antithrombin iii in treating acute lung injury |
| US20050169908A1 (en) * | 2004-01-23 | 2005-08-04 | Kazunori Murakami | Use of aerosolized antithrombin to treat acute lung injury |
| US20050192226A1 (en) * | 2004-02-20 | 2005-09-01 | Perenlei Enkhbaatar | Method of preventing fibrin clots in pulmonary tissue through the use of aerosolized anticoagulants |
-
2005
- 2005-02-14 US US11/057,522 patent/US20050192226A1/en not_active Abandoned
- 2005-02-15 WO PCT/US2005/004604 patent/WO2005081816A2/en not_active Ceased
- 2005-02-15 JP JP2006554156A patent/JP2007533657A/ja active Pending
- 2005-02-15 KR KR1020067019275A patent/KR20060130661A/ko not_active Ceased
- 2005-02-15 EP EP05713495A patent/EP1725244B1/en not_active Expired - Lifetime
- 2005-02-15 CA CA002557411A patent/CA2557411A1/en not_active Abandoned
- 2005-02-15 EP EP10177819A patent/EP2322189A3/en not_active Withdrawn
- 2005-02-15 DE DE602005025610T patent/DE602005025610D1/de not_active Expired - Lifetime
- 2005-02-15 AU AU2005216044A patent/AU2005216044B2/en not_active Ceased
- 2005-02-15 AT AT05713495T patent/ATE493135T1/de not_active IP Right Cessation
- 2005-02-15 KR KR1020097027466A patent/KR20100017971A/ko not_active Abandoned
- 2005-02-15 KR KR1020117015353A patent/KR20110084555A/ko not_active Ceased
-
2006
- 2006-08-20 IL IL177588A patent/IL177588A0/en unknown
-
2010
- 2010-09-10 US US12/879,235 patent/US20110070167A1/en not_active Abandoned
-
2011
- 2011-05-16 JP JP2011109632A patent/JP2011162555A/ja active Pending
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