CA2553758A1 - Use of aerosolized antithrombin to treat acute lung injury - Google Patents
Use of aerosolized antithrombin to treat acute lung injury Download PDFInfo
- Publication number
- CA2553758A1 CA2553758A1 CA002553758A CA2553758A CA2553758A1 CA 2553758 A1 CA2553758 A1 CA 2553758A1 CA 002553758 A CA002553758 A CA 002553758A CA 2553758 A CA2553758 A CA 2553758A CA 2553758 A1 CA2553758 A1 CA 2553758A1
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- Prior art keywords
- atiii
- lung injury
- protein
- antithrombin iii
- antithrombin
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
- A61K35/14—Blood; Artificial blood
- A61K35/16—Blood plasma; Blood serum
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/55—Protease inhibitors
- A61K38/57—Protease inhibitors from animals; from humans
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/43—Enzymes; Proenzymes; Derivatives thereof
- A61K38/46—Hydrolases (3)
- A61K38/48—Hydrolases (3) acting on peptide bonds (3.4)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Immunology (AREA)
- Epidemiology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Gastroenterology & Hepatology (AREA)
- Zoology (AREA)
- Hematology (AREA)
- Cell Biology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pulmonology (AREA)
- Biomedical Technology (AREA)
- Biotechnology (AREA)
- Developmental Biology & Embryology (AREA)
- Virology (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US53867804P | 2004-01-23 | 2004-01-23 | |
| US60/538,678 | 2004-01-23 | ||
| US11/034,590 | 2005-01-13 | ||
| US11/034,590 US20050169908A1 (en) | 2004-01-23 | 2005-01-13 | Use of aerosolized antithrombin to treat acute lung injury |
| PCT/US2005/001238 WO2005072139A2 (en) | 2004-01-23 | 2005-01-14 | Use of aerosolized antithrombin to treat acute lung injury |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CA2553758A1 true CA2553758A1 (en) | 2005-08-11 |
Family
ID=34810485
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA002553758A Abandoned CA2553758A1 (en) | 2004-01-23 | 2005-01-14 | Use of aerosolized antithrombin to treat acute lung injury |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US20050169908A1 (https=) |
| EP (1) | EP1713500A2 (https=) |
| JP (1) | JP4854519B2 (https=) |
| KR (1) | KR20060127992A (https=) |
| AU (1) | AU2005208552A1 (https=) |
| CA (1) | CA2553758A1 (https=) |
| IL (1) | IL177028A0 (https=) |
| WO (1) | WO2005072139A2 (https=) |
Families Citing this family (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR20100117148A (ko) * | 2002-04-01 | 2010-11-02 | 지티씨바이오쎄라퓨틱스,인크. | 폐 질환의 치료 방법 |
| US20050192226A1 (en) * | 2004-02-20 | 2005-09-01 | Perenlei Enkhbaatar | Method of preventing fibrin clots in pulmonary tissue through the use of aerosolized anticoagulants |
| US20050245444A1 (en) * | 2004-04-30 | 2005-11-03 | Yann Echelard | Method of using recombinant human antithrombin for neurocognitive disorders |
| US20060121004A1 (en) * | 2004-12-07 | 2006-06-08 | Yann Echelard | Methods of reducing the incidence of rejection in tissue transplantation through the use of recombinant human antithrombin |
| KR20140093603A (ko) | 2010-12-30 | 2014-07-28 | 라보라토이레 프란카이즈 듀 프락티온네먼트 에트 데스 바이오테크놀로지스 | 병원체 불활성화제로서의 글리콜 |
| EP2928480B1 (en) | 2012-12-05 | 2019-09-25 | National Jewish Health | Treatment for airway cast obstruction |
| US10034921B2 (en) | 2013-02-13 | 2018-07-31 | Laboratoire Français Du Fractionnement Et Des Biotechnologies | Proteins with modified glycosylation and methods of production thereof |
| EP3594231A1 (en) | 2013-02-13 | 2020-01-15 | Laboratoire Français du Fractionnement et des Biotechnologies | Highly galactosylated anti-tnf-alpha antibodies and uses thereof |
| MX384222B (es) | 2013-07-05 | 2025-03-14 | Lab Francais Du Fractionnement | Matriz de cromatografia de afinidad. |
| MX2016005720A (es) | 2013-11-04 | 2016-11-25 | Univ Texas | Composiciones y metodos para administracion de una enzima a las vias respiratorias de un sujeto. |
| US10668015B2 (en) * | 2015-01-20 | 2020-06-02 | Incarda Therapeutics, Inc. | Unit aerosol doses for anticoagulation |
| WO2016179447A1 (en) * | 2015-05-06 | 2016-11-10 | Board Of Regents, The University Of Texas System | Compositions and methods for administration of an enzyme to a subject's airway |
| FR3038517B1 (fr) | 2015-07-06 | 2020-02-28 | Laboratoire Francais Du Fractionnement Et Des Biotechnologies | Utilisation de fragments fc modifies en immunotherapie |
| US11654036B2 (en) | 2020-05-26 | 2023-05-23 | Elixir Medical Corporation | Anticoagulant compounds and methods and devices for their use |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6127347A (en) * | 1994-01-12 | 2000-10-03 | Univ Michigan | Non-anticoagulant chemically modified heparinoids for treating hypovolemic shock and related shock syndromes |
| US5843705A (en) * | 1995-02-21 | 1998-12-01 | Genzyme Transgenic Corporation | Transgenically produced antithrombin III |
| US7045585B2 (en) * | 1995-11-30 | 2006-05-16 | Hamilton Civic Hospital Research Development Inc. | Methods of coating a device using anti-thrombin heparin |
| US6063593A (en) * | 1996-11-12 | 2000-05-16 | University Of Southern California University Park Campus | TGFβ1 responsive bone marrow derived cells to express a recombinant protein |
| US6124257A (en) * | 1997-08-28 | 2000-09-26 | Lezdey; John | Method of treatment |
| DE10132307A1 (de) * | 2001-07-06 | 2003-01-30 | Aventis Behring Gmbh | Arzneizubereitung zur Inhalation von Antithrombin bei entzündlichen Lungenerkrankungen und ARDS |
| KR20100117148A (ko) * | 2002-04-01 | 2010-11-02 | 지티씨바이오쎄라퓨틱스,인크. | 폐 질환의 치료 방법 |
| US20050192226A1 (en) * | 2004-02-20 | 2005-09-01 | Perenlei Enkhbaatar | Method of preventing fibrin clots in pulmonary tissue through the use of aerosolized anticoagulants |
-
2005
- 2005-01-13 US US11/034,590 patent/US20050169908A1/en not_active Abandoned
- 2005-01-14 AU AU2005208552A patent/AU2005208552A1/en not_active Abandoned
- 2005-01-14 WO PCT/US2005/001238 patent/WO2005072139A2/en not_active Ceased
- 2005-01-14 EP EP05705713A patent/EP1713500A2/en not_active Withdrawn
- 2005-01-14 KR KR1020067016937A patent/KR20060127992A/ko not_active Abandoned
- 2005-01-14 JP JP2006551170A patent/JP4854519B2/ja not_active Expired - Fee Related
- 2005-01-14 CA CA002553758A patent/CA2553758A1/en not_active Abandoned
-
2006
- 2006-07-23 IL IL177028A patent/IL177028A0/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| KR20060127992A (ko) | 2006-12-13 |
| JP4854519B2 (ja) | 2012-01-18 |
| JP2007518801A (ja) | 2007-07-12 |
| EP1713500A2 (en) | 2006-10-25 |
| IL177028A0 (en) | 2006-12-10 |
| US20050169908A1 (en) | 2005-08-04 |
| AU2005208552A1 (en) | 2005-08-11 |
| WO2005072139A3 (en) | 2006-01-05 |
| WO2005072139A2 (en) | 2005-08-11 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| EEER | Examination request | ||
| FZDE | Discontinued |