JP2007516327A - 反応性親水性オリゴマー - Google Patents
反応性親水性オリゴマー Download PDFInfo
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- JP2007516327A JP2007516327A JP2006543809A JP2006543809A JP2007516327A JP 2007516327 A JP2007516327 A JP 2007516327A JP 2006543809 A JP2006543809 A JP 2006543809A JP 2006543809 A JP2006543809 A JP 2006543809A JP 2007516327 A JP2007516327 A JP 2007516327A
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- 239000003039 volatile agent Substances 0.000 description 1
- 239000002759 woven fabric Substances 0.000 description 1
- 229920001285 xanthan gum Polymers 0.000 description 1
- 235000010493 xanthan gum Nutrition 0.000 description 1
- 239000000230 xanthan gum Substances 0.000 description 1
- 229940082509 xanthan gum Drugs 0.000 description 1
- 239000008096 xylene Substances 0.000 description 1
- 229910052727 yttrium Inorganic materials 0.000 description 1
- 239000010457 zeolite Substances 0.000 description 1
- UHVMMEOXYDMDKI-JKYCWFKZSA-L zinc;1-(5-cyanopyridin-2-yl)-3-[(1s,2s)-2-(6-fluoro-2-hydroxy-3-propanoylphenyl)cyclopropyl]urea;diacetate Chemical compound [Zn+2].CC([O-])=O.CC([O-])=O.CCC(=O)C1=CC=C(F)C([C@H]2[C@H](C2)NC(=O)NC=2N=CC(=CC=2)C#N)=C1O UHVMMEOXYDMDKI-JKYCWFKZSA-L 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L15/00—Chemical aspects of, or use of materials for, bandages, dressings or absorbent pads
- A61L15/16—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons
- A61L15/22—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons containing macromolecular materials
- A61L15/26—Macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds; Derivatives thereof
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08F—MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
- C08F257/00—Macromolecular compounds obtained by polymerising monomers on to polymers of aromatic monomers as defined in group C08F12/00
- C08F257/02—Macromolecular compounds obtained by polymerising monomers on to polymers of aromatic monomers as defined in group C08F12/00 on to polymers of styrene or alkyl-substituted styrenes
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08F—MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
- C08F265/00—Macromolecular compounds obtained by polymerising monomers on to polymers of unsaturated monocarboxylic acids or derivatives thereof as defined in group C08F20/00
- C08F265/04—Macromolecular compounds obtained by polymerising monomers on to polymers of unsaturated monocarboxylic acids or derivatives thereof as defined in group C08F20/00 on to polymers of esters
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08F—MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
- C08F291/00—Macromolecular compounds obtained by polymerising monomers on to macromolecular compounds according to more than one of the groups C08F251/00 - C08F289/00
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08L—COMPOSITIONS OF MACROMOLECULAR COMPOUNDS
- C08L33/00—Compositions of homopolymers or copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and only one being terminated by only one carboxyl radical, or of salts, anhydrides, esters, amides, imides or nitriles thereof; Compositions of derivatives of such polymers
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08L—COMPOSITIONS OF MACROMOLECULAR COMPOUNDS
- C08L39/00—Compositions of homopolymers or copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and at least one being terminated by a single or double bond to nitrogen or by a heterocyclic ring containing nitrogen; Compositions of derivatives of such polymers
- C08L39/04—Homopolymers or copolymers of monomers containing heterocyclic rings having nitrogen as ring member
- C08L39/06—Homopolymers or copolymers of N-vinyl-pyrrolidones
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08L—COMPOSITIONS OF MACROMOLECULAR COMPOUNDS
- C08L51/00—Compositions of graft polymers in which the grafted component is obtained by reactions only involving carbon-to-carbon unsaturated bonds; Compositions of derivatives of such polymers
- C08L51/003—Compositions of graft polymers in which the grafted component is obtained by reactions only involving carbon-to-carbon unsaturated bonds; Compositions of derivatives of such polymers grafted on to macromolecular compounds obtained by reactions only involving unsaturated carbon-to-carbon bonds
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Medicinal Chemistry (AREA)
- Polymers & Plastics (AREA)
- Organic Chemistry (AREA)
- Materials Engineering (AREA)
- Engineering & Computer Science (AREA)
- Hematology (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Macromonomer-Based Addition Polymer (AREA)
- Materials For Medical Uses (AREA)
- Other Resins Obtained By Reactions Not Involving Carbon-To-Carbon Unsaturated Bonds (AREA)
- Addition Polymer Or Copolymer, Post-Treatments, Or Chemical Modifications (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US10/732,715 US7384984B2 (en) | 2003-12-10 | 2003-12-10 | Reactive hydrophilic oligomers |
| PCT/US2004/035720 WO2005061012A1 (en) | 2003-12-10 | 2004-10-28 | Reactive hydrophilic oligomers |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2007516327A true JP2007516327A (ja) | 2007-06-21 |
| JP2007516327A5 JP2007516327A5 (https=) | 2007-12-13 |
Family
ID=34652926
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2006543809A Pending JP2007516327A (ja) | 2003-12-10 | 2004-10-28 | 反応性親水性オリゴマー |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US7384984B2 (https=) |
| EP (1) | EP1691850B1 (https=) |
| JP (1) | JP2007516327A (https=) |
| KR (1) | KR20060121162A (https=) |
| CN (1) | CN100512887C (https=) |
| AT (1) | ATE500853T1 (https=) |
| DE (1) | DE602004031757D1 (https=) |
| WO (1) | WO2005061012A1 (https=) |
Families Citing this family (19)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6635690B2 (en) * | 2001-06-19 | 2003-10-21 | 3M Innovative Properties Company | Reactive oligomers |
| US20050070688A1 (en) * | 2003-09-26 | 2005-03-31 | 3M Innovative Properties Company | Reactive hydrophilic oligomers |
| US7074839B2 (en) * | 2004-03-01 | 2006-07-11 | 3M Innovative Properties Company | Crosslinkable hydrophilic materials from reactive oligomers having pendent photoinitiator groups |
| US7342047B2 (en) * | 2004-03-02 | 2008-03-11 | 3M Innovative Properties Company | Crosslinkable hydrophilic materials from reactive oligomers having pendent unsaturated groups |
| US8224414B2 (en) | 2004-10-28 | 2012-07-17 | Echo Therapeutics, Inc. | System and method for analyte sampling and analysis with hydrogel |
| US7842762B2 (en) * | 2007-08-08 | 2010-11-30 | Ppg Industries Ohio, Inc. | Electrodepositable coating composition containing a cyclic guanidine |
| US8580875B2 (en) * | 2007-12-12 | 2013-11-12 | Ashland Licensing And Intellectual Property Llc | Acrylic emulsion polymers for removable pressure sensitive adhesive applications |
| US8329469B2 (en) * | 2008-01-30 | 2012-12-11 | Geron Corporation | Swellable (meth)acrylate surfaces for culturing cells in chemically defined media |
| EP2247718B1 (en) | 2008-01-30 | 2019-01-16 | Asterias Biotherapeutics, Inc. | Synthetic surfaces for culturing stem cell derived cardiomyocytes |
| US8354274B2 (en) * | 2008-01-30 | 2013-01-15 | Geron Corporation | Synthetic surfaces for culturing cells in chemically defined media |
| WO2009099539A2 (en) * | 2008-01-30 | 2009-08-13 | Corning Incorporated | (meth)acrylate surfaces for cell culture, methods of making and using the surfaces |
| SG188096A1 (en) | 2008-01-30 | 2013-03-28 | Geron Corp | Synthetic surfaces for culturing stem cell derived oligodendrocyte progenitor cells |
| US8362144B2 (en) * | 2009-05-21 | 2013-01-29 | Corning Incorporated | Monomers for making polymeric cell culture surface |
| US8563560B2 (en) | 2011-02-25 | 2013-10-22 | Ppg Industries Ohio, Inc. | Preparation of bicyclic guanidine salts in an aqueous media |
| US9068089B2 (en) | 2013-03-15 | 2015-06-30 | Ppg Industries Ohio, Inc. | Phenolic admix for electrodepositable coating composition containing a cyclic guanidine |
| US9688874B2 (en) | 2013-10-25 | 2017-06-27 | Ppg Industries Ohio, Inc. | Method of making a bicyclic guanidine-cured acrylic coating |
| WO2021081036A1 (en) * | 2019-10-21 | 2021-04-29 | Biocoat, Inc. | Uv cure coatings for medical devices |
| US12037560B2 (en) | 2019-10-21 | 2024-07-16 | Biocoat, Incorporated | UV cure topcoatings for medical devices |
| US12214146B2 (en) * | 2019-12-11 | 2025-02-04 | Biocoat, Incorporated | Controlled release of a hydrophilic agent from a coated surface |
Citations (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS51109094A (ja) * | 1975-03-20 | 1976-09-27 | Nitto Electric Ind Co | Hidorokishiarukiruakurireeto mataha metakurireetoosuchirenkoorigomaano seizohoho |
| JPH05247175A (ja) * | 1992-03-04 | 1993-09-24 | Kansai Paint Co Ltd | 自己架橋性樹脂 |
| WO2000001424A1 (en) * | 1998-07-07 | 2000-01-13 | Nof Corporation | Wound-covering preparation, wound-covering material, and method of wound healing |
| JP2000297129A (ja) * | 1999-02-08 | 2000-10-24 | Toyota Central Res & Dev Lab Inc | 水分散性樹脂および塗膜の形成方法 |
| JP2002012729A (ja) * | 2000-06-28 | 2002-01-15 | Hitachi Chem Co Ltd | 水溶性樹脂組成物 |
| WO2002102909A1 (en) * | 2001-06-19 | 2002-12-27 | 3M Innovative Properties Company | Reactive oligomers |
Family Cites Families (44)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA677797A (en) * | 1955-11-18 | 1964-01-14 | Minnesota Mining And Manufacturing Company | Sheet material having a pressure-sensitive adhesive coating of acrylate ester copolymer |
| US3121021A (en) * | 1960-04-18 | 1964-02-11 | Minnesota Mining & Mfg | Breathable surgical adhesive tapes |
| US4112213A (en) * | 1964-09-28 | 1978-09-05 | Johnson & Johnson | Pressure sensitive adhesive tapes and method of making same |
| US3389827A (en) * | 1967-04-10 | 1968-06-25 | Minnesota Mining & Mfg | Easy-open container and sealing tape |
| BR7606383A (pt) * | 1975-09-26 | 1977-06-14 | Bayer Ag | Processo para a preparacao de poliuretanos |
| DE2555534C3 (de) * | 1975-12-10 | 1981-01-08 | Bayer Ag, 5090 Leverkusen | In Wasser dispergierbare Polyurethane |
| US4385164A (en) * | 1976-03-10 | 1983-05-24 | The Goodyear Tire & Rubber Company | Block copolymer dispersion stabilizer and aqueous dispersion polymerization therewith |
| DE2642073C2 (de) * | 1976-09-18 | 1984-08-16 | Bayer Ag, 5090 Leverkusen | Verfahren zur Herstellung eines vernetzten Flächengebildes |
| US4499896A (en) * | 1982-03-30 | 1985-02-19 | Minnesota Mining And Manufacturing Co. | Reservoir wound dressing |
| US4598004A (en) * | 1985-01-24 | 1986-07-01 | Minnesota Mining And Manufacturing Company | Thin film surgical dressing with delivery system |
| US4680352A (en) * | 1985-03-01 | 1987-07-14 | E. I. Du Pont De Nemours And Company | Cobalt (II) chelates as chain transfer agents in free radical polymerizations |
| US4694054A (en) * | 1985-03-01 | 1987-09-15 | E. I. Du Pont De Nemours And Company | Cobalt(II) chelates as chain transfer agents in free radical polymerizations |
| US4849458A (en) * | 1988-06-17 | 1989-07-18 | Matrix Medica, Inc. | Segmented polyether polyurethane |
| US5264530A (en) * | 1992-05-01 | 1993-11-23 | E. I. Du Pont De Nemours And Company | Process of polymerization in an aqueous system |
| US5773534A (en) * | 1992-05-22 | 1998-06-30 | E. I. Du Pont De Nemours And Company | Preparing crosslinkable polymers employing macromonomer chain transfer agents |
| AU682853B2 (en) * | 1993-03-22 | 1997-10-23 | Minnesota Mining And Manufacturing Company | Windowless frame delivered dressing and method of manufacture |
| US5506279A (en) * | 1993-10-13 | 1996-04-09 | Minnesota Mining And Manufacturing Company | Acrylamido functional disubstituted acetyl aryl ketone photoinitiators |
| KR970704849A (ko) * | 1994-07-29 | 1997-09-06 | 워렌 리차드 보비 | 가교 점탄성 물질로 경화가능한 아크릴 시럽 |
| US5653699A (en) * | 1994-09-13 | 1997-08-05 | Polymedica Industries, Inc. | Spyrosorbent wound dressings for exudate management |
| US5614310A (en) * | 1994-11-04 | 1997-03-25 | Minnesota Mining And Manufacturing Company | Low trauma wound dressing with improved moisture vapor permeability |
| KR100390687B1 (ko) * | 1995-02-10 | 2005-05-31 | 미네소타 마이닝 앤드 매뉴팩춰링 캄파니 | 가교된압력민감성접착제로피복된제품의생산방법 |
| US5587431A (en) * | 1995-04-21 | 1996-12-24 | E. I. Du Pont De Nemours And Company | Synthesis of terminally unsaturated oligomers |
| US5733570A (en) * | 1996-09-05 | 1998-03-31 | Minnesota Mining And Manufacturing Company | Absorbent dressing |
| US5849325A (en) * | 1996-10-07 | 1998-12-15 | Minnesota Mining And Manufacturing Company | Moisture-regulating adhesive dressing |
| ATE216501T1 (de) * | 1997-02-21 | 2002-05-15 | Novartis Erfind Verwalt Gmbh | Opthalmische formmasse |
| US6420622B1 (en) | 1997-08-01 | 2002-07-16 | 3M Innovative Properties Company | Medical article having fluid control film |
| CA2304096C (en) | 1997-09-18 | 2003-09-09 | Pacira Pharmaceuticals, Inc. | Sustained-release liposomal anesthetic compositions |
| FR2768341B1 (fr) | 1997-09-18 | 2000-04-14 | Lab Francais Du Fractionnement | Composition pharmaceutique placebo lyophilisable destinee a imiter un medicament, notamment a base de proteines ou de polypeptides |
| US6171985B1 (en) * | 1997-12-01 | 2001-01-09 | 3M Innovative Properties Company | Low trauma adhesive article |
| US6007833A (en) * | 1998-03-19 | 1999-12-28 | Surmodics, Inc. | Crosslinkable macromers bearing initiator groups |
| US6198016B1 (en) * | 1998-12-01 | 2001-03-06 | 3M Innovative Properties Company | Wet skin adhesive article |
| US6361768B1 (en) * | 1998-12-29 | 2002-03-26 | Pmd Holdings Corp. | Hydrophilic ampholytic polymer |
| TW497165B (en) * | 1999-06-30 | 2002-08-01 | Hitachi Ltd | Method for manufacturing semiconductor integrated circuit device, optical mask used therefor, method for manufacturing the same, and mask blanks used therefor |
| DK1218437T3 (da) * | 1999-08-27 | 2009-10-19 | Angiodevice Internat Gmbh | Præparater, som danner interpenetrerende polymernetværk, til anvendelse som medicinske tætningsmidler med höj styrke |
| JP2003508605A (ja) | 1999-09-07 | 2003-03-04 | アルコン，インコーポレイテッド | 眼科および耳鼻咽喉科用の装置材料 |
| US6566575B1 (en) | 2000-02-15 | 2003-05-20 | 3M Innovative Properties Company | Patterned absorbent article for wound dressing |
| CA2400228C (en) * | 2000-03-10 | 2008-11-18 | 3M Innovative Properties Company | Medical dressings with multiple adhesives and methods of manufacturing |
| US6448301B1 (en) * | 2000-09-08 | 2002-09-10 | 3M Innovative Properties Company | Crosslinkable polymeric compositions and use thereof |
| US6559223B2 (en) * | 2001-02-22 | 2003-05-06 | Polytechnic University | Hydrogels and methods for their production |
| EP1390084B1 (en) * | 2001-05-01 | 2011-03-23 | A.V. Topchiev Institute of Petrochemical Synthesis | Two-phase, water-absorbent bioadhesive composition |
| US7005143B2 (en) * | 2002-04-12 | 2006-02-28 | 3M Innovative Properties Company | Gel materials, medical articles, and methods |
| US7148265B2 (en) | 2002-09-30 | 2006-12-12 | Rohm And Haas Electronic Materials Llc | Functional polymer |
| US20050070688A1 (en) * | 2003-09-26 | 2005-03-31 | 3M Innovative Properties Company | Reactive hydrophilic oligomers |
| US8609131B2 (en) * | 2005-01-25 | 2013-12-17 | 3M Innovative Properties Company | Absorbent dressing comprising hydrophilic polymer prepared via Michael reaction |
-
2003
- 2003-12-10 US US10/732,715 patent/US7384984B2/en not_active Expired - Lifetime
-
2004
- 2004-10-28 KR KR1020067011367A patent/KR20060121162A/ko not_active Ceased
- 2004-10-28 WO PCT/US2004/035720 patent/WO2005061012A1/en not_active Ceased
- 2004-10-28 CN CNB2004800369398A patent/CN100512887C/zh not_active Expired - Fee Related
- 2004-10-28 EP EP04796589A patent/EP1691850B1/en not_active Expired - Lifetime
- 2004-10-28 DE DE602004031757T patent/DE602004031757D1/de not_active Expired - Lifetime
- 2004-10-28 JP JP2006543809A patent/JP2007516327A/ja active Pending
- 2004-10-28 AT AT04796589T patent/ATE500853T1/de not_active IP Right Cessation
Patent Citations (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS51109094A (ja) * | 1975-03-20 | 1976-09-27 | Nitto Electric Ind Co | Hidorokishiarukiruakurireeto mataha metakurireetoosuchirenkoorigomaano seizohoho |
| JPH05247175A (ja) * | 1992-03-04 | 1993-09-24 | Kansai Paint Co Ltd | 自己架橋性樹脂 |
| WO2000001424A1 (en) * | 1998-07-07 | 2000-01-13 | Nof Corporation | Wound-covering preparation, wound-covering material, and method of wound healing |
| JP2000297129A (ja) * | 1999-02-08 | 2000-10-24 | Toyota Central Res & Dev Lab Inc | 水分散性樹脂および塗膜の形成方法 |
| JP2002012729A (ja) * | 2000-06-28 | 2002-01-15 | Hitachi Chem Co Ltd | 水溶性樹脂組成物 |
| WO2002102909A1 (en) * | 2001-06-19 | 2002-12-27 | 3M Innovative Properties Company | Reactive oligomers |
| JP2004532926A (ja) * | 2001-06-19 | 2004-10-28 | スリーエム イノベイティブ プロパティズ カンパニー | 反応性オリゴマー |
Also Published As
| Publication number | Publication date |
|---|---|
| EP1691850A1 (en) | 2006-08-23 |
| EP1691850B1 (en) | 2011-03-09 |
| KR20060121162A (ko) | 2006-11-28 |
| WO2005061012A1 (en) | 2005-07-07 |
| CN1889982A (zh) | 2007-01-03 |
| US20050131148A1 (en) | 2005-06-16 |
| CN100512887C (zh) | 2009-07-15 |
| DE602004031757D1 (de) | 2011-04-21 |
| US7384984B2 (en) | 2008-06-10 |
| ATE500853T1 (de) | 2011-03-15 |
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