JP2007516227A5 - - Google Patents
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- Publication number
- JP2007516227A5 JP2007516227A5 JP2006533150A JP2006533150A JP2007516227A5 JP 2007516227 A5 JP2007516227 A5 JP 2007516227A5 JP 2006533150 A JP2006533150 A JP 2006533150A JP 2006533150 A JP2006533150 A JP 2006533150A JP 2007516227 A5 JP2007516227 A5 JP 2007516227A5
- Authority
- JP
- Japan
- Prior art keywords
- compound
- disease
- formula
- group
- pharmaceutically acceptable
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
Links
Applications Claiming Priority (9)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US47142503P | 2003-05-16 | 2003-05-16 | |
| US48047503P | 2003-06-20 | 2003-06-20 | |
| US48028903P | 2003-06-20 | 2003-06-20 | |
| US48817803P | 2003-07-16 | 2003-07-16 | |
| US48817203P | 2003-07-16 | 2003-07-16 | |
| US51661603P | 2003-10-30 | 2003-10-30 | |
| US51665103P | 2003-10-30 | 2003-10-30 | |
| US51661003P | 2003-10-30 | 2003-10-30 | |
| PCT/US2004/015444 WO2004110998A1 (en) | 2003-05-16 | 2004-05-17 | Pyrrole compounds and uses thereof |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2007516227A JP2007516227A (ja) | 2007-06-21 |
| JP2007516227A5 true JP2007516227A5 (https=) | 2007-08-02 |
Family
ID=33479880
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2006533154A Pending JP2007500219A (ja) | 2003-05-16 | 2004-05-17 | 複素環化合物およびその使用法 |
| JP2006533150A Withdrawn JP2007516227A (ja) | 2003-05-16 | 2004-05-17 | ピロール化合物およびその使用 |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2006533154A Pending JP2007500219A (ja) | 2003-05-16 | 2004-05-17 | 複素環化合物およびその使用法 |
Country Status (6)
| Country | Link |
|---|---|
| US (3) | US20040242673A1 (https=) |
| EP (2) | EP1636183A1 (https=) |
| JP (2) | JP2007500219A (https=) |
| AU (2) | AU2004247023A1 (https=) |
| CA (2) | CA2523858A1 (https=) |
| WO (4) | WO2004110357A2 (https=) |
Families Citing this family (48)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB0302094D0 (en) | 2003-01-29 | 2003-02-26 | Pharmagene Lab Ltd | EP4 receptor antagonists |
| GB0324269D0 (en) * | 2003-10-16 | 2003-11-19 | Pharmagene Lab Ltd | EP4 receptor antagonists |
| ES2311986T3 (es) * | 2004-04-26 | 2009-02-16 | Alcon, Inc. | Estatinas para el tratamiento de la hipertension ocular y del glaucoma. |
| EP1671947A1 (en) * | 2004-12-20 | 2006-06-21 | Ratiopharm GmbH | Process for preparing pyrrole derivatives and intermediates |
| TWI444187B (zh) | 2005-01-25 | 2014-07-11 | Synta Pharmaceuticals Corp | 用於炎症及免疫相關用途之噻吩化合物 |
| BRPI0610283A2 (pt) | 2005-05-13 | 2010-10-19 | Virochem Pharma Inc | composto, uso do mesmo na preparação de um medicamento para o tratamento ou prevenção de uma infecção por vìrus de hepatite c, composição farmacêutica e combinação farmacêutica |
| KR20080064956A (ko) | 2005-09-27 | 2008-07-10 | 미리어드 제네틱스, 인크. | 치료학적 화합물로서의 피롤 유도체 |
| WO2007056457A2 (en) | 2005-11-09 | 2007-05-18 | Combinatorx, Incorporated | Methods, compositions, and kits for the treatment of medical conditions |
| US7592362B2 (en) | 2006-01-19 | 2009-09-22 | Pfizer Limited | Substituted imidazoles |
| WO2007087441A2 (en) | 2006-01-25 | 2007-08-02 | Synta Pharmaceuticals Corp. | Substituted aromatic compounds for inflammation and immune-related uses |
| MX2008010187A (es) | 2006-02-10 | 2008-10-31 | Summit Corp Plc | Tratamiento de distrofia muscular de duchenne. |
| US9187485B2 (en) | 2007-02-02 | 2015-11-17 | Baylor College Of Medicine | Methods and compositions for the treatment of cancer and related hyperproliferative disorders |
| EP2120580B1 (en) * | 2007-02-02 | 2017-12-27 | Baylor College Of Medicine | Compositions and methods for the treatment of metabolic disorders |
| US8048880B2 (en) | 2007-05-03 | 2011-11-01 | Anthera Pharmaceuticals, Inc. | Treatment of cardiovascular disease and dyslipidemia using secretory phospholipase A2 (SPLA2) inhibitors and SPLA2 inhibitor combination therapies |
| JP2010535708A (ja) * | 2007-08-03 | 2010-11-25 | ビオマリン アイジーエー リミテッド | デュシェンヌ型筋ジストロフィーの治療のための薬物併用 |
| GB0715937D0 (en) * | 2007-08-15 | 2007-09-26 | Vastox Plc | Method of treatment og duchenne muscular dystrophy |
| JP5567481B2 (ja) | 2007-10-09 | 2014-08-06 | メルク パテント ゲゼルシャフト ミット ベシュレンクテル ハフツング | グルコキナーゼアクチベーターとして有用なピリジン誘導体 |
| US20110009463A1 (en) * | 2007-10-17 | 2011-01-13 | Yuri Karl Petersson | Geranylgeranyl transferase inhibitors and methods of making and using the same |
| AR069126A1 (es) | 2007-10-31 | 2009-12-30 | Janssen Pharmaceutica Nv | Diaminas en puente o fusionadas sustituidas con arilo como moduladores de leucotrieno a4 hidrolasa |
| KR20090070233A (ko) * | 2007-12-27 | 2009-07-01 | 동아제약주식회사 | 피롤릴헵탄산 화합물의 합성 중간체 및 신규 중간체를이용한 제조방법 |
| KR100856133B1 (ko) * | 2008-01-11 | 2008-09-03 | 조동옥 | 아토르바스타틴의 개선된 제조방법 |
| DE102008007400A1 (de) | 2008-02-04 | 2009-08-06 | Bayer Healthcare Ag | Substituierte Furane und ihre Verwendung |
| SI2336125T1 (sl) | 2008-04-11 | 2013-04-30 | Janssen Pharmaceutica N.V. | Tiazolopiridin-2-iloksi-fenil in tiazolopirazin-2-iloksi-fenil amini kot modulatorji levkotrien a4 hidrolaze |
| US9447049B2 (en) * | 2010-03-01 | 2016-09-20 | University Of Tennessee Research Foundation | Compounds for treatment of cancer |
| US9029408B2 (en) | 2008-06-16 | 2015-05-12 | Gtx, Inc. | Compounds for treatment of cancer |
| AU2009330686B2 (en) | 2008-06-16 | 2014-07-03 | The Ohio State University Research Foundation | Compounds for the treatment of cancer |
| WO2010056413A2 (en) * | 2008-11-14 | 2010-05-20 | Parkinson's Institute | COMPOSITIONS AND METHODS FOR THE TREATMENT OF ALTERED α-SYNUCLEIN FUNCTION |
| CN102459251B (zh) | 2009-05-14 | 2015-05-20 | 詹森药业有限公司 | 作为白三烯a4水解酶的调节剂的具有两个稠合双环杂芳基部分的化合物 |
| US11084811B2 (en) | 2010-03-01 | 2021-08-10 | Oncternal Therapeutics, Inc. | Compounds for treatment of cancer |
| MX2012010115A (es) | 2010-03-01 | 2013-02-26 | Gtx Inc | Compuestos para el tratamiento de cancer. |
| MX2012014273A (es) | 2010-06-07 | 2013-03-22 | Novomedix Llc | Compuestos furanilo y su uso. |
| WO2011154677A1 (en) * | 2010-06-09 | 2011-12-15 | Astrazeneca Ab | Substituted n-[1-cyano-2-(phenyl)ethyl] 1-aminocycloalk-1-ylcarboxamide compounds - 760 |
| US20140057953A1 (en) * | 2011-03-03 | 2014-02-27 | Rolf Hartmann | Biaryl derivatives as selective 17beta-hydroxysteroid dehydrogenase type 2 inhibitors |
| US20120328526A1 (en) * | 2011-06-27 | 2012-12-27 | University Of Maryland, Baltimore | Modulation of Nad+ Activity in Neuropathophysiological Conditions and Uses Thereof |
| JP6835472B2 (ja) | 2013-03-05 | 2021-02-24 | ユニバーシティ オブ テネシー リサーチ ファウンデーション | 癌の処置のための組成物 |
| WO2014169087A2 (en) * | 2013-04-10 | 2014-10-16 | The Trustees Of Columbia University In The City Of New York | Treatment of proximal spinal muscular atrophy |
| CN107074839A (zh) * | 2013-08-29 | 2017-08-18 | 贝勒医学院 | 用于治疗代谢和体重相关的病症的组合物和方法 |
| WO2016029263A1 (en) * | 2014-08-25 | 2016-03-03 | Wang Bing Hui | Mapk inhibitors |
| ES2977619T3 (es) | 2017-05-11 | 2024-08-27 | Remynd N V | Compuestos para el tratamiento de la epilepsia, trastornos neurodegenerativos y otros trastornos del SNC |
| EP3634407A1 (en) * | 2017-05-11 | 2020-04-15 | Remynd N.V. | Inhibitors of pde6delta for use in the prevention and/or treatment of epilepsy and/or neurodegenerative disorders |
| CN108101891B (zh) * | 2017-12-06 | 2020-08-21 | 浙江科技学院 | 一种阿托伐他汀中间体的制备方法 |
| BR112020022220A2 (pt) * | 2018-06-01 | 2021-02-02 | Autophagysciences Inc. | novo composto e composição farmacêutica compreendendo o mesmo |
| US20220265646A1 (en) * | 2019-07-08 | 2022-08-25 | Itä-Suomen Yliopisto | Piezo agonists for preventing or reverting abnormal amyloid deposition |
| WO2021041744A1 (en) * | 2019-08-30 | 2021-03-04 | University Of Tennessee Research Foundation | Ryl benzoyl imidazole compounds for the treatment of lung cancer |
| WO2023028117A1 (en) * | 2021-08-24 | 2023-03-02 | Yeh, Teng-Kuang | Methods of treating cdgsh iron sulfur domain 2 insufficiency-associated disorders |
| WO2023101556A1 (en) | 2021-12-02 | 2023-06-08 | Rijksuniversiteit Groningen | Novel inhibitors of aspartate transcarbamoylase (atcase) and compositions, methods and uses related thereto. |
| JPWO2023145831A1 (https=) * | 2022-01-28 | 2023-08-03 | ||
| CN117510430B (zh) * | 2024-01-08 | 2024-10-25 | 南昌大学 | 一种噁唑类化合物及其合成方法与应用 |
Family Cites Families (56)
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| US2714082A (en) * | 1955-07-26 | New oxazoline derivatives | ||
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| JPS5612114B2 (https=) * | 1974-06-07 | 1981-03-18 | ||
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| JPS53147073A (en) * | 1977-05-24 | 1978-12-21 | Sankyo Co Ltd | Mevalonolactone derivatives |
| JPS5559180A (en) * | 1978-10-30 | 1980-05-02 | Sankyo Co Ltd | 4-hydroxy-2-pyrone ring compound, its preparation, and remedy for hyperlipemia comprising it as active constituent |
| US4375475A (en) * | 1979-08-17 | 1983-03-01 | Merck & Co., Inc. | Substituted pyranone inhibitors of cholesterol synthesis |
| ATE11770T1 (de) * | 1981-12-14 | 1985-02-15 | Sandoz-Erfindungen Verwaltungsgesellschaft M.B.H. | N,n,disubstituierte alkenamide und phenylaldenamide, verfahren zu deren herstellung und deren verwendung als pharmazeutika. |
| DK161312C (da) * | 1982-03-11 | 1991-12-09 | Pfizer | Analogifremgangsmaade til fremstilling af 2-aminoalkoxymethyl-4-phenyl-6-methyl-1,4-dihydropyridin-3,5-dicarboxylsyreestere eller syreadditionssalte deraf samt phthalimidoderivater til anvendelse som udgangsmateriale ved fremgangsmaaden |
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| CA2139442A1 (en) * | 1992-07-03 | 1994-01-20 | David Haigh | Heterocyclic compounds as pharmaceutical |
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| GT199800127A (es) * | 1997-08-29 | 2000-02-01 | Combinaciones terapeuticas. | |
| CA2304505A1 (en) * | 1997-09-24 | 1999-04-01 | Nova Molecular, Inc. | Methods for increasing apoe levels for the treatment of neurodegenerative disease |
| CN1280574A (zh) * | 1997-10-27 | 2001-01-17 | 雷迪研究基金会 | 新的杂环化合物及其在医药中的应用、它们的制备方法和含有它们的药物组合物 |
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| JP4496586B2 (ja) * | 2000-01-24 | 2010-07-07 | 日産化学工業株式会社 | キノリルアクリロニトリルの製造法及びその中間体 |
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| JP2005532982A (ja) | 2001-09-24 | 2005-11-04 | バイエル・フアーマシユーチカルズ・コーポレーシヨン | 肥満の処置のためのピロール誘導体の製造及び使用 |
| CA2464314A1 (en) * | 2001-11-22 | 2003-05-30 | Ciba Specialty Chemicals Holding Inc. | Pyrrole synthesis |
| WO2003055479A1 (en) | 2001-12-21 | 2003-07-10 | Consejo Superior De Investigaciones Cientificas | Compounds and their therapeutic use related to the phosphorylating activity of the enzyme gsk-3 |
| EP1466902A4 (en) | 2001-12-28 | 2005-11-09 | Takeda Pharmaceutical | ANTAGONISTS OF THE ANDROGEN RECEPTOR |
| AU2003203143B2 (en) | 2002-02-01 | 2009-05-14 | High Point Pharmaceuticals, Llc | Amides of aminoalkyl-substituted azetidines, pyrrolidines, piperidines and azepanes |
| HUP0201083A2 (hu) | 2002-03-28 | 2004-06-28 | Richter Gedeon Vegyészeti Gyár Rt. | Új atorvastatinsók és az azokat tartalmazó gyógyszerkészítmények |
| US20030186221A1 (en) * | 2002-04-02 | 2003-10-02 | Lockhart David J. | Phage display affinity filter and forward screen |
| AU2003234089A1 (en) | 2002-04-12 | 2003-10-27 | Henry Ford Health System | Treatment of neural injury and neurodegenerative disease with statins |
| AU2004266232B2 (en) * | 2003-08-15 | 2008-07-03 | Merck Sharp & Dohme Corp. | Mitotic kinesin inhibitors |
-
2004
- 2004-05-17 US US10/847,897 patent/US20040242673A1/en not_active Abandoned
- 2004-05-17 US US10/848,521 patent/US20040248957A1/en not_active Abandoned
- 2004-05-17 JP JP2006533154A patent/JP2007500219A/ja active Pending
- 2004-05-17 JP JP2006533150A patent/JP2007516227A/ja not_active Withdrawn
- 2004-05-17 WO PCT/US2004/015450 patent/WO2004110357A2/en not_active Ceased
- 2004-05-17 AU AU2004247023A patent/AU2004247023A1/en not_active Abandoned
- 2004-05-17 CA CA002523858A patent/CA2523858A1/en not_active Abandoned
- 2004-05-17 EP EP04752457A patent/EP1636183A1/en not_active Withdrawn
- 2004-05-17 WO PCT/US2004/015444 patent/WO2004110998A1/en not_active Ceased
- 2004-05-17 CA CA002523808A patent/CA2523808A1/en not_active Abandoned
- 2004-05-17 EP EP04752463A patent/EP1626713A2/en not_active Withdrawn
- 2004-05-17 WO PCT/US2004/015543 patent/WO2004103960A2/en not_active Ceased
- 2004-05-17 AU AU2004247627A patent/AU2004247627A1/en not_active Abandoned
- 2004-05-17 WO PCT/US2004/015542 patent/WO2004103959A2/en not_active Ceased
- 2004-05-18 US US10/848,584 patent/US7323490B2/en not_active Expired - Fee Related
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