|
US7550470B2
(en)
*
|
2002-12-11 |
2009-06-23 |
Merck & Co. Inc. |
Substituted pyrazolo[1,5-A]pyrimidines as tyrosine kinase inhibitors
|
|
TWI377198B
(en)
|
2005-08-24 |
2012-11-21 |
Eisai R&D Man Co Ltd |
Novel pyridine derivatives and pyrimidine derivatives (3)
|
|
RU2419620C2
(ru)
*
|
2005-11-30 |
2011-05-27 |
Вертекс Фармасьютикалз Инкорпорейтед |
Ингибиторы с-мет и их применение
|
|
US7728017B2
(en)
*
|
2005-11-30 |
2010-06-01 |
Vertex Pharmaceuticals Incorporated |
Inhibitors of c-Met and uses thereof
|
|
ZA200804681B
(en)
*
|
2005-11-30 |
2009-11-25 |
Vertex Pharma Inc |
Inhibitors of C-Met and uses thereof
|
|
RS55630B1
(sr)
*
|
2005-12-21 |
2017-06-30 |
Janssen Pharmaceutica Nv |
Triazolopiridazini kao modulatori tirozin kinaze
|
|
US7723330B2
(en)
|
2006-03-07 |
2010-05-25 |
Array Biopharma Inc. |
Heterobicyclic pyrazole compounds and methods of use
|
|
US20110053931A1
(en)
*
|
2006-06-08 |
2011-03-03 |
John Gaudino |
Quinoline compounds and methods of use
|
|
US8198448B2
(en)
|
2006-07-14 |
2012-06-12 |
Amgen Inc. |
Fused heterocyclic derivatives and methods of use
|
|
US8217177B2
(en)
|
2006-07-14 |
2012-07-10 |
Amgen Inc. |
Fused heterocyclic derivatives and methods of use
|
|
PE20121506A1
(es)
*
|
2006-07-14 |
2012-11-26 |
Amgen Inc |
Compuestos triazolopiridinas como inhibidores de c-met
|
|
US7683060B2
(en)
*
|
2006-08-07 |
2010-03-23 |
Incyte Corporation |
Triazolotriazines as kinase inhibitors
|
|
ATE535520T1
(de)
|
2006-08-23 |
2011-12-15 |
Eisai R&D Man Co Ltd |
Salz eines phenoxypyridinderivats oder kristall davon und verfahren zu dessen herstellung
|
|
US7790885B2
(en)
|
2006-08-31 |
2010-09-07 |
Eisai R&D Management Co., Ltd. |
Process for preparing phenoxypyridine derivatives
|
|
WO2008030744A2
(en)
*
|
2006-09-05 |
2008-03-13 |
Board Of Regents, The University Of Texas System |
Inhibitors of c-met and uses thereof
|
|
NZ575548A
(en)
*
|
2006-09-18 |
2011-09-30 |
Vertex Pharma |
Heterocyclic inhibitors of c-Met and uses thereof
|
|
BRPI0717320A2
(pt)
*
|
2006-10-23 |
2013-10-22 |
Sgx Pharmaceuticals Inc |
Triazóis bicíclicos como moduladores de proteína cinase
|
|
MX2009004426A
(es)
|
2006-10-23 |
2009-08-12 |
Cephalon Inc |
Derivados biciclicos fusionados de 2,4-diaminopirimidina como inhibidores alk y c-met.
|
|
GEP20125658B
(en)
*
|
2006-11-22 |
2012-10-10 |
Incyte Corp |
Imidazotriazines and imidazo pyrimidines as kinase inhibitors
|
|
AU2007338792B2
(en)
|
2006-12-20 |
2012-05-31 |
Amgen Inc. |
Substituted heterocycles and methods of use
|
|
WO2008079294A1
(en)
*
|
2006-12-20 |
2008-07-03 |
Amgen Inc. |
Substituted heterocycles and methods of use
|
|
US8066118B1
(en)
|
2006-12-25 |
2011-11-29 |
Marty Van Tassell |
Device for using nonwoven towels in the dairy industry
|
|
EP2170894A1
(en)
*
|
2007-06-21 |
2010-04-07 |
Janssen Pharmaceutica N.V. |
Polymorphic and hydrate forms, salts and process for preparing 6-{difluoro[6-(1-methyl-1h-pyrazol-4-yl)[1,2,4]triazolo[4,3-b]pyridazin-3-yl]methyl}quinoline
|
|
JP2009132660A
(ja)
|
2007-11-30 |
2009-06-18 |
Eisai R & D Management Co Ltd |
食道癌治療用組成物
|
|
PE20091468A1
(es)
|
2008-02-28 |
2009-10-22 |
Novartis Ag |
DERIVADOS DE 3-METIL-IMIDAZO-[1,2-b]-PIRIDAZINA
|
|
SI2300455T1
(sl)
|
2008-05-21 |
2017-12-29 |
Incyte Holdings Corporation |
Soli 2-fluoro-n-metil-4-(7-(kinolin-6-il-metil)-imidazo(1,2-b)1,2,4) triazin-2-il)benzamid in postopki v zvezi z njihovo pripravo
|
|
JP2011520986A
(ja)
|
2008-05-22 |
2011-07-21 |
アムジエン・インコーポレーテツド |
タンパク質キナーゼ阻害薬としての複素環類
|
|
EP2321433A2
(en)
*
|
2008-08-29 |
2011-05-18 |
F. Hoffmann-La Roche AG |
Diagnostics and treatments for vegf-independent tumors
|
|
AU2009300328A1
(en)
*
|
2008-10-01 |
2010-04-08 |
Ludwig Institute For Cancer Research |
Methods for the treatment of cancer
|
|
EP2356116A1
(en)
|
2008-11-20 |
2011-08-17 |
OSI Pharmaceuticals, Inc. |
Substituted pyrroloý2,3-b¨-pyridines and-pyrazines
|
|
UA106082C2
(uk)
*
|
2009-05-28 |
2014-07-25 |
Вертекс Фармасьютікалз Інкорпорейтед |
АМІНОПІРАЗОЛ ТРИАЗОЛОТІАДІАЗОЛЬНІ ІНГІБІТОРИ ПРОТЕЇНКІНАЗИ c-МЕТ
|
|
US8389526B2
(en)
|
2009-08-07 |
2013-03-05 |
Novartis Ag |
3-heteroarylmethyl-imidazo[1,2-b]pyridazin-6-yl derivatives
|
|
BR112012003262A8
(pt)
|
2009-08-12 |
2016-05-17 |
Novartis Ag |
compostos de hidrazona heterocíclica e seus usos para tratar câncer e inflamação
|
|
IN2012DN01453A
(cg-RX-API-DMAC10.html)
|
2009-08-20 |
2015-06-05 |
Novartis Ag |
|
|
PT3511330T
(pt)
|
2009-12-31 |
2020-12-24 |
Hutchison Medipharma Ltd |
Intermediário sintético útil na preparação de inibidores de triazolopiridina c-met
|
|
MX2012008898A
(es)
|
2010-02-03 |
2012-11-06 |
Incyte Corp |
Imidazo - [1, 2 - b] [1, 2, 4] triazinas como inhibidores de c - met.
|
|
US20130072495A1
(en)
|
2010-05-14 |
2013-03-21 |
OSI Pharmaceuticals, LLC |
Fused bicyclic kinase inhibitors
|
|
AR081039A1
(es)
|
2010-05-14 |
2012-05-30 |
Osi Pharmaceuticals Llc |
Inhibidores biciclicos fusionados de quinasa
|
|
CN102532141A
(zh)
|
2010-12-08 |
2012-07-04 |
中国科学院上海药物研究所 |
[1,2,4]三唑并[4,3-b][1,2,4]三嗪类化合物、其制备方法和用途
|
|
JP2014513724A
(ja)
|
2011-05-16 |
2014-06-05 |
オーエスアイ・ファーマシューティカルズ,エルエルシー |
融合二環キナーゼ阻害剤
|
|
WO2013152252A1
(en)
|
2012-04-06 |
2013-10-10 |
OSI Pharmaceuticals, LLC |
Combination anti-cancer therapy
|
|
EP3122900A1
(en)
|
2014-03-24 |
2017-02-01 |
F. Hoffmann-La Roche AG |
Cancer treatment with c-met antagonists and correlation of the latter with hgf expression
|
|
CN111205291B
(zh)
*
|
2018-11-22 |
2022-08-23 |
上海科技大学 |
三唑并环类化合物、其制备方法、中间体和应用
|