JP2007516169A5 - - Google Patents
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- Publication number
- JP2007516169A5 JP2007516169A5 JP2006516555A JP2006516555A JP2007516169A5 JP 2007516169 A5 JP2007516169 A5 JP 2007516169A5 JP 2006516555 A JP2006516555 A JP 2006516555A JP 2006516555 A JP2006516555 A JP 2006516555A JP 2007516169 A5 JP2007516169 A5 JP 2007516169A5
- Authority
- JP
- Japan
- Prior art keywords
- alkyl
- optionally substituted
- heteroaryl
- cycloalkyl
- aryl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US48348903P | 2003-06-27 | 2003-06-27 | |
| PCT/IB2004/001989 WO2005000303A1 (en) | 2003-06-27 | 2004-06-14 | Pyrazolo`3,4-b!pyridin-6-ones as gsk-3 inhibitors |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2007516169A JP2007516169A (ja) | 2007-06-21 |
| JP2007516169A5 true JP2007516169A5 (https=) | 2007-08-02 |
| JP4680897B2 JP4680897B2 (ja) | 2011-05-11 |
Family
ID=33552061
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2006516555A Expired - Fee Related JP4680897B2 (ja) | 2003-06-27 | 2004-06-14 | Ｇｓｋ−３阻害薬としてのピラゾロ［３，４−ｂ］ピリジン−６−オン類 |
Country Status (11)
| Country | Link |
|---|---|
| US (1) | US7300943B2 (https=) |
| EP (1) | EP1641454B1 (https=) |
| JP (1) | JP4680897B2 (https=) |
| AT (1) | ATE409480T1 (https=) |
| BR (1) | BRPI0411891A (https=) |
| CA (1) | CA2529083A1 (https=) |
| DE (1) | DE602004016850D1 (https=) |
| DK (1) | DK1641454T3 (https=) |
| ES (1) | ES2313014T3 (https=) |
| MX (1) | MXPA05014201A (https=) |
| WO (1) | WO2005000303A1 (https=) |
Families Citing this family (22)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2006130673A1 (en) | 2005-05-31 | 2006-12-07 | Janssen Pharmaceutica, N.V. | 3-benzoimidazolyl-pyrazolopyridines useful in treating kinase disorders |
| EP2258358A3 (en) | 2005-08-26 | 2011-09-07 | Braincells, Inc. | Neurogenesis with acetylcholinesterase inhibitor |
| EP2275095A3 (en) | 2005-08-26 | 2011-08-17 | Braincells, Inc. | Neurogenesis by muscarinic receptor modulation |
| EP1940389A2 (en) | 2005-10-21 | 2008-07-09 | Braincells, Inc. | Modulation of neurogenesis by pde inhibition |
| AU2006308889A1 (en) | 2005-10-31 | 2007-05-10 | Braincells, Inc. | GABA receptor mediated modulation of neurogenesis |
| WO2007076055A2 (en) * | 2005-12-22 | 2007-07-05 | Entremed, Inc. | Compositions and methods comprising proteinase activated receptor antagonists |
| US8193238B2 (en) * | 2006-03-08 | 2012-06-05 | University Of Maryland, Baltimore | Inhibition of microtubule protrusion in cancer cells |
| US20100216734A1 (en) | 2006-03-08 | 2010-08-26 | Braincells, Inc. | Modulation of neurogenesis by nootropic agents |
| EP2382975A3 (en) | 2006-05-09 | 2012-02-29 | Braincells, Inc. | Neurogenesis by modulating angiotensin |
| US20100184806A1 (en) | 2006-09-19 | 2010-07-22 | Braincells, Inc. | Modulation of neurogenesis by ppar agents |
| JP2008074788A (ja) * | 2006-09-22 | 2008-04-03 | Rohto Pharmaceut Co Ltd | エラスチン産生促進剤 |
| WO2008136948A1 (en) * | 2007-05-07 | 2008-11-13 | Amgen Inc. | Pyrazolo-pyridinone and pyrazolo-pyrazinone compounds as p38 modulators, process for their preparation, and their pharmaceutical use |
| WO2008137176A1 (en) * | 2007-05-07 | 2008-11-13 | Amgen Inc. | Pyrazolo-pyridinone compounds, process for their preparation, and their pharmaceutical use |
| US20100210644A1 (en) * | 2007-06-25 | 2010-08-19 | Boehringer Ingelheim International Gmbh | Chemical compounds |
| WO2009017453A1 (en) * | 2007-07-30 | 2009-02-05 | Astrazeneca Ab | New therapeutic combination of an antipsychotic and a gsk3 inhibitor 958 |
| MX2010002692A (es) | 2007-09-13 | 2010-06-01 | Concert Pharmaceuticals Inc | Sintesis de catecoles deuterados y derivados de benzo[d][1,3]dioxoles de los mismos. |
| GB0719299D0 (en) | 2007-10-03 | 2007-11-14 | Optinose As | Nasal delivery devices |
| FR2931677B1 (fr) * | 2008-06-02 | 2010-08-20 | Sanofi Aventis | Association d'un agoniste partiel des recepteurs nicotiniques et d'un inhibiteur d'acetylcholinesterase, composition la contenant et son utilisation dans le traitement des troubles cognitifs |
| WO2010099217A1 (en) | 2009-02-25 | 2010-09-02 | Braincells, Inc. | Modulation of neurogenesis using d-cycloserine combinations |
| US20140206667A1 (en) | 2012-11-14 | 2014-07-24 | Michela Gallagher | Methods and compositions for treating schizophrenia |
| CA2945263A1 (en) | 2014-04-09 | 2015-10-15 | Christopher Rudd | Use of gsk-3 inhibitors or activators which modulate pd-1 or t-bet expression to modulate t cell immunity |
| WO2023011456A1 (en) * | 2021-08-03 | 2023-02-09 | Beigene, Ltd. | Pyrazolopyridinone compounds |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE138773C (https=) | ||||
| US4020072A (en) * | 1976-05-04 | 1977-04-26 | E. R. Squibb & Sons, Inc. | 5-Aminomethyl-1H-pyrazolo[3,4-b]pyridines |
| DD138773A1 (de) * | 1978-09-15 | 1979-11-21 | Helmut Dorn | Verfahren zur herstellung von 6,7-dihydro-6-oxo-pyr&zolo eckige klammer auf 3,4-b eckige klammer zu-pyridinen |
| US7109199B2 (en) * | 2000-09-22 | 2006-09-19 | Smithkline Beecham Corporation | Pyrazolopyridines and pyrazolopyridazines as antidiabetics |
| AU2002222293A1 (en) * | 2000-12-19 | 2002-07-01 | Smithkline Beecham P.L.C. | Pyrazolo(3,4-c)pyridines as gsk-3 inhibitors |
| GB0128287D0 (en) * | 2001-11-26 | 2002-01-16 | Smithkline Beecham Plc | Novel method and compounds |
-
2004
- 2004-06-14 AT AT04736777T patent/ATE409480T1/de not_active IP Right Cessation
- 2004-06-14 BR BRPI0411891-0A patent/BRPI0411891A/pt not_active IP Right Cessation
- 2004-06-14 ES ES04736777T patent/ES2313014T3/es not_active Expired - Lifetime
- 2004-06-14 EP EP04736777A patent/EP1641454B1/en not_active Expired - Lifetime
- 2004-06-14 DK DK04736777T patent/DK1641454T3/da active
- 2004-06-14 CA CA002529083A patent/CA2529083A1/en not_active Abandoned
- 2004-06-14 DE DE602004016850T patent/DE602004016850D1/de not_active Expired - Lifetime
- 2004-06-14 WO PCT/IB2004/001989 patent/WO2005000303A1/en not_active Ceased
- 2004-06-14 MX MXPA05014201A patent/MXPA05014201A/es not_active Application Discontinuation
- 2004-06-14 JP JP2006516555A patent/JP4680897B2/ja not_active Expired - Fee Related
- 2004-06-23 US US10/874,962 patent/US7300943B2/en not_active Expired - Fee Related
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