JP2007516169A5 - - Google Patents
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- Publication number
- JP2007516169A5 JP2007516169A5 JP2006516555A JP2006516555A JP2007516169A5 JP 2007516169 A5 JP2007516169 A5 JP 2007516169A5 JP 2006516555 A JP2006516555 A JP 2006516555A JP 2006516555 A JP2006516555 A JP 2006516555A JP 2007516169 A5 JP2007516169 A5 JP 2007516169A5
- Authority
- JP
- Japan
- Prior art keywords
- alkyl
- optionally substituted
- heteroaryl
- cycloalkyl
- aryl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US48348903P | 2003-06-27 | 2003-06-27 | |
| PCT/IB2004/001989 WO2005000303A1 (en) | 2003-06-27 | 2004-06-14 | Pyrazolo`3,4-b!pyridin-6-ones as gsk-3 inhibitors |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2007516169A JP2007516169A (ja) | 2007-06-21 |
| JP2007516169A5 true JP2007516169A5 (enExample) | 2007-08-02 |
| JP4680897B2 JP4680897B2 (ja) | 2011-05-11 |
Family
ID=33552061
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2006516555A Expired - Fee Related JP4680897B2 (ja) | 2003-06-27 | 2004-06-14 | Ｇｓｋ−３阻害薬としてのピラゾロ［３，４−ｂ］ピリジン−６−オン類 |
Country Status (11)
| Country | Link |
|---|---|
| US (1) | US7300943B2 (enExample) |
| EP (1) | EP1641454B1 (enExample) |
| JP (1) | JP4680897B2 (enExample) |
| AT (1) | ATE409480T1 (enExample) |
| BR (1) | BRPI0411891A (enExample) |
| CA (1) | CA2529083A1 (enExample) |
| DE (1) | DE602004016850D1 (enExample) |
| DK (1) | DK1641454T3 (enExample) |
| ES (1) | ES2313014T3 (enExample) |
| MX (1) | MXPA05014201A (enExample) |
| WO (1) | WO2005000303A1 (enExample) |
Families Citing this family (22)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7541367B2 (en) | 2005-05-31 | 2009-06-02 | Janssen Pharmaceutica, N.V. | 3-benzoimidazolyl-pyrazolopyridines useful in treating kinase disorders |
| EP2258357A3 (en) | 2005-08-26 | 2011-04-06 | Braincells, Inc. | Neurogenesis with acetylcholinesterase inhibitor |
| AU2006282896A1 (en) | 2005-08-26 | 2007-03-01 | Braincells, Inc. | Neurogenesis by muscarinic receptor modulation |
| WO2007047978A2 (en) | 2005-10-21 | 2007-04-26 | Braincells, Inc. | Modulation of neurogenesis by pde inhibition |
| JP2009513672A (ja) | 2005-10-31 | 2009-04-02 | ブレインセルス，インコーポレイティド | 神経発生のｇａｂａ受容体媒介調節 |
| WO2007076055A2 (en) * | 2005-12-22 | 2007-07-05 | Entremed, Inc. | Compositions and methods comprising proteinase activated receptor antagonists |
| EP2001462A4 (en) * | 2006-03-08 | 2010-02-24 | Univ Maryland | INHIBITION OF MICROTUBULUS PROTRUSION IN CANCER CELLS |
| US20100216734A1 (en) | 2006-03-08 | 2010-08-26 | Braincells, Inc. | Modulation of neurogenesis by nootropic agents |
| EP2377531A2 (en) | 2006-05-09 | 2011-10-19 | Braincells, Inc. | Neurogenesis by modulating angiotensin |
| US20100184806A1 (en) | 2006-09-19 | 2010-07-22 | Braincells, Inc. | Modulation of neurogenesis by ppar agents |
| JP2008074788A (ja) * | 2006-09-22 | 2008-04-03 | Rohto Pharmaceut Co Ltd | エラスチン産生促進剤 |
| US8022085B2 (en) * | 2007-05-07 | 2011-09-20 | Amgen Inc. | Pyrazolo-pyridinone and pyrazolo-pyrazinone compounds as P38 modulators and methods of use thereof |
| WO2008137176A1 (en) * | 2007-05-07 | 2008-11-13 | Amgen Inc. | Pyrazolo-pyridinone compounds, process for their preparation, and their pharmaceutical use |
| US20100210644A1 (en) * | 2007-06-25 | 2010-08-19 | Boehringer Ingelheim International Gmbh | Chemical compounds |
| WO2009017453A1 (en) * | 2007-07-30 | 2009-02-05 | Astrazeneca Ab | New therapeutic combination of an antipsychotic and a gsk3 inhibitor 958 |
| JP5647519B2 (ja) | 2007-09-13 | 2014-12-24 | コンサート ファーマシューティカルズ インコーポレイテッド | 重水素化カテコールおよびベンゾ［ｄ］［１，３］ジオキソールおよびその誘導体の合成 |
| GB0719299D0 (en) | 2007-10-03 | 2007-11-14 | Optinose As | Nasal delivery devices |
| FR2931677B1 (fr) * | 2008-06-02 | 2010-08-20 | Sanofi Aventis | Association d'un agoniste partiel des recepteurs nicotiniques et d'un inhibiteur d'acetylcholinesterase, composition la contenant et son utilisation dans le traitement des troubles cognitifs |
| WO2010099217A1 (en) | 2009-02-25 | 2010-09-02 | Braincells, Inc. | Modulation of neurogenesis using d-cycloserine combinations |
| EP3610890A1 (en) | 2012-11-14 | 2020-02-19 | The Johns Hopkins University | Methods and compositions for treating schizophrenia |
| US20170165230A1 (en) | 2014-04-09 | 2017-06-15 | Christopher Rudd | Use of gsk-3 inhibitors or activators which modulate pd-1 or t-bet expression to modulate t cell immunity |
| CN117836296A (zh) * | 2021-08-03 | 2024-04-05 | 百济神州有限公司 | 吡唑并吡啶酮化合物 |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE138773C (enExample) | ||||
| US4020072A (en) * | 1976-05-04 | 1977-04-26 | E. R. Squibb & Sons, Inc. | 5-Aminomethyl-1H-pyrazolo[3,4-b]pyridines |
| DD138773A1 (de) * | 1978-09-15 | 1979-11-21 | Helmut Dorn | Verfahren zur herstellung von 6,7-dihydro-6-oxo-pyr&zolo eckige klammer auf 3,4-b eckige klammer zu-pyridinen |
| WO2002024694A1 (en) * | 2000-09-22 | 2002-03-28 | Smithkline Beecham, P.L.C. | Pyrazolopyridines and pyrazolopyridazines as antidiabetics |
| EP1347972A1 (en) * | 2000-12-19 | 2003-10-01 | Smithkline Beecham Plc | Pyrazolo 3,4-c]pyridines as gsk-3 inhibitors |
| GB0128287D0 (en) * | 2001-11-26 | 2002-01-16 | Smithkline Beecham Plc | Novel method and compounds |
-
2004
- 2004-06-14 BR BRPI0411891-0A patent/BRPI0411891A/pt not_active IP Right Cessation
- 2004-06-14 CA CA002529083A patent/CA2529083A1/en not_active Abandoned
- 2004-06-14 ES ES04736777T patent/ES2313014T3/es not_active Expired - Lifetime
- 2004-06-14 EP EP04736777A patent/EP1641454B1/en not_active Expired - Lifetime
- 2004-06-14 AT AT04736777T patent/ATE409480T1/de not_active IP Right Cessation
- 2004-06-14 MX MXPA05014201A patent/MXPA05014201A/es not_active Application Discontinuation
- 2004-06-14 DK DK04736777T patent/DK1641454T3/da active
- 2004-06-14 WO PCT/IB2004/001989 patent/WO2005000303A1/en not_active Ceased
- 2004-06-14 JP JP2006516555A patent/JP4680897B2/ja not_active Expired - Fee Related
- 2004-06-14 DE DE602004016850T patent/DE602004016850D1/de not_active Expired - Lifetime
- 2004-06-23 US US10/874,962 patent/US7300943B2/en not_active Expired - Fee Related
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